BIO CEO Presentation - Trillium Therapeutics Inc.
... This presentation may contain forward-looking statements, which reflect Trillium's current expectation regarding future events. These forward-looking statements involve risks and uncertainties that may cause actual results, events or developments to be materially different from any future results, ...
... This presentation may contain forward-looking statements, which reflect Trillium's current expectation regarding future events. These forward-looking statements involve risks and uncertainties that may cause actual results, events or developments to be materially different from any future results, ...
Pathology, Mechanisms of Pathogenicity and Disease
... phagocytic WBCs including capsules, M-proteins and A-proteins. Microorganisms may produce substances that kill phagocytic WBCs such as leukocidins, or they may cause the lysis of immune cells such as T4 lymphocytes (as does HIV). Sometimes pathogens are taken into WBCs via phagocytosis, but rather t ...
... phagocytic WBCs including capsules, M-proteins and A-proteins. Microorganisms may produce substances that kill phagocytic WBCs such as leukocidins, or they may cause the lysis of immune cells such as T4 lymphocytes (as does HIV). Sometimes pathogens are taken into WBCs via phagocytosis, but rather t ...
Diagnosis
... the area affected into a single score in the range 0 (no disease) to 72 (maximal disease). ...
... the area affected into a single score in the range 0 (no disease) to 72 (maximal disease). ...
No Slide Title
... – ADP causes circulating platelets to become sticky – adhere to the first layer of aggregating platelets – results in the secretion of more ADP by the incoming platelets – release of serotonin, epinephrine and thromboxane act as vasoconstrictors to reinforce the ...
... – ADP causes circulating platelets to become sticky – adhere to the first layer of aggregating platelets – results in the secretion of more ADP by the incoming platelets – release of serotonin, epinephrine and thromboxane act as vasoconstrictors to reinforce the ...
type_III_and_IV_HS_r..
... 4-The TH1 cells secrete IFN-γ, which is the most potent macrophageactivating cytokine known. 5-Macrophages produce substances that cause tissue damage and promote fibrosis, and TH17 secrete IL-17 and other cytokines recruit leukocytes ...
... 4-The TH1 cells secrete IFN-γ, which is the most potent macrophageactivating cytokine known. 5-Macrophages produce substances that cause tissue damage and promote fibrosis, and TH17 secrete IL-17 and other cytokines recruit leukocytes ...
Defense Lecture Study ppt. part 2 File
... • Billions of antibodies result from somatic recombination of gene segments • Hypervariable regions of some genes increase antibody variation through somatic mutations • Each plasma cell can switch the type of H chain produced, making an antibody of a different class ...
... • Billions of antibodies result from somatic recombination of gene segments • Hypervariable regions of some genes increase antibody variation through somatic mutations • Each plasma cell can switch the type of H chain produced, making an antibody of a different class ...
"Immunological Accessory Molecules".
... various immune cells to specific sites in the body. Factors that regulate expression of adhesion molecules can therefore control where and when immune cells travel. Extravasation from the vascular system begins with a process called rolling in which the cells are induced to move more slowly than othe ...
... various immune cells to specific sites in the body. Factors that regulate expression of adhesion molecules can therefore control where and when immune cells travel. Extravasation from the vascular system begins with a process called rolling in which the cells are induced to move more slowly than othe ...
A novel approach to HIV therapy: Highly active antiretroviral therapy
... virus pool in those instances in which patients exhibit no detectable HIV-1 replication during receipt of HAART. In other words, virus evolution is restricted if antiretroviral therapy can maintain virus loads at undetectable levels for a prolonged period [6]. New approaches are now being developed ...
... virus pool in those instances in which patients exhibit no detectable HIV-1 replication during receipt of HAART. In other words, virus evolution is restricted if antiretroviral therapy can maintain virus loads at undetectable levels for a prolonged period [6]. New approaches are now being developed ...
Tolerance - BHS116.3 Physiology III
... • Review mechanisms of T cell tolerance. • Describe the factors involved in the breakdown of tolerance. • Define autoimmunity. • Describe autoimmune diseases, concentrating on the role of immunity in their pathogenesis. • Readings: Robbins, Chapter 5 ...
... • Review mechanisms of T cell tolerance. • Describe the factors involved in the breakdown of tolerance. • Define autoimmunity. • Describe autoimmune diseases, concentrating on the role of immunity in their pathogenesis. • Readings: Robbins, Chapter 5 ...
RA-Conference.-Nov.-6-8-2009ppt-1
... results strongly suggesting they are not ab le to amplify from any endogenous retroviruses in the human genome. Given the phylogenetic distance between HIV and HERV this is not surprising. However, your question is interesting in th at a colleague of mine Dr Robert Gifford has conducted work using c ...
... results strongly suggesting they are not ab le to amplify from any endogenous retroviruses in the human genome. Given the phylogenetic distance between HIV and HERV this is not surprising. However, your question is interesting in th at a colleague of mine Dr Robert Gifford has conducted work using c ...
ppt_ch26_e_body defence mechanisms
... • faster, stronger and lasts longer • memory cells multiply and differentiate quickly into a larger number of plasma cells, killer T cells and memory cells • kills the pathogen before it can multiply and cause a disease ...
... • faster, stronger and lasts longer • memory cells multiply and differentiate quickly into a larger number of plasma cells, killer T cells and memory cells • kills the pathogen before it can multiply and cause a disease ...
VAN 504 Lecture 06
... The deepest layer of the eye ball is the internal (nervous) tunic or retina. The light- sensitive part of the retina extends from just posterior to the ciliary body to the site at which nerve fibers exit the eyeball near the posterior pole of the globe. ...
... The deepest layer of the eye ball is the internal (nervous) tunic or retina. The light- sensitive part of the retina extends from just posterior to the ciliary body to the site at which nerve fibers exit the eyeball near the posterior pole of the globe. ...
File
... Cytochrome c, well known for its role in mitochondrial respiration. Once released into the cytosol, cytochrome c binds to a protein called Apaf-1 (apoptosis-activating factor-1, homologous to Ced-4 in C. elegans), which forms a wheel-like hexamer that has been called the apoptosome. This complex is ...
... Cytochrome c, well known for its role in mitochondrial respiration. Once released into the cytosol, cytochrome c binds to a protein called Apaf-1 (apoptosis-activating factor-1, homologous to Ced-4 in C. elegans), which forms a wheel-like hexamer that has been called the apoptosome. This complex is ...
Classification of allergens
... • Pathophysiological stage. Usually immune complexes are placed on vessels of cannalicular apparatus of kidneys, inflammation with alteration, exudation and proliferation (glomerulonephritis) develops, in case if the complexes are placed in the lungs alveolitis appears, in skin – dermatitis. The inf ...
... • Pathophysiological stage. Usually immune complexes are placed on vessels of cannalicular apparatus of kidneys, inflammation with alteration, exudation and proliferation (glomerulonephritis) develops, in case if the complexes are placed in the lungs alveolitis appears, in skin – dermatitis. The inf ...
Bio - UNM Internal Medicine
... therapeutics. Dr. Bradfute has also found, through careful review of the literature and his own published work, that many of the Ebola virus vaccines that are protective in monkeys appear to utilize different immune cell subsets to generate protection, strongly suggesting that there is no single me ...
... therapeutics. Dr. Bradfute has also found, through careful review of the literature and his own published work, that many of the Ebola virus vaccines that are protective in monkeys appear to utilize different immune cell subsets to generate protection, strongly suggesting that there is no single me ...
Document
... clinical trials. VLPs represent an exciting new strategy for HIV vaccines but it has been difficult to ...
... clinical trials. VLPs represent an exciting new strategy for HIV vaccines but it has been difficult to ...
The Lymphatic System
... • The skin – Physical barrier to foreign materials – pH of the skin is acidic to inhibit bacterial growth • Sebum is toxic to bacteria • Vaginal secretions are very acidic ...
... • The skin – Physical barrier to foreign materials – pH of the skin is acidic to inhibit bacterial growth • Sebum is toxic to bacteria • Vaginal secretions are very acidic ...
Robert A. Weinberg the biology of
... 13.3 Tumors resemble wounded tissues that do not heal 13.4 Experiments directly demonstrate that stromal cells are active contributors to tumorigenesis 13.5 Macrophages and myeloid cells play important roles in activating the tumor-associated stroma 13.6 Endothelial cells and the vessels that ...
... 13.3 Tumors resemble wounded tissues that do not heal 13.4 Experiments directly demonstrate that stromal cells are active contributors to tumorigenesis 13.5 Macrophages and myeloid cells play important roles in activating the tumor-associated stroma 13.6 Endothelial cells and the vessels that ...
Power Point Presentation
... • Following an injury, mast cells release histamine, which promotes changes in blood vessels; this is part of the inflammatory response • These changes increase local blood supply and allow more phagocytes and antimicrobial proteins to enter tissues • Pus, a fluid rich in white blood cells, dead mic ...
... • Following an injury, mast cells release histamine, which promotes changes in blood vessels; this is part of the inflammatory response • These changes increase local blood supply and allow more phagocytes and antimicrobial proteins to enter tissues • Pus, a fluid rich in white blood cells, dead mic ...
Innate immune system
The innate immune system, also known as the nonspecific immune system, is an important subsystem of the overall immune system that comprises the cells and mechanisms that defend the host from infection by other organisms. The cells of the innate system recognize and respond to pathogens in a generic way, but, unlike the adaptive immune system (which is found only in vertebrates), it does not confer long-lasting or protective immunity to the host. Innate immune systems provide immediate defense against infection, and are found in all classes of plant and animal life. They include both humoral immunity components and cell-mediated immunity components.The innate immune system is an evolutionarily older defense strategy, and is the dominant immune system found in plants, fungi, insects, and primitive multicellular organisms.The major functions of the vertebrate innate immune system include: Recruiting immune cells to sites of infection, through the production of chemical factors, including specialized chemical mediators, called cytokines Activation of the complement cascade to identify bacteria, activate cells, and promote clearance of antibody complexes or dead cells The identification and removal of foreign substances present in organs, tissues, the blood and lymph, by specialised white blood cells Activation of the adaptive immune system through a process known as antigen presentation Acting as a physical and chemical barrier to infectious agents.↑ ↑ ↑