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1 Continue… 2nd part Morphology Primary Tuberculosis. In
1 Continue… 2nd part Morphology Primary Tuberculosis. In

... of successive attacks of relapsing fever and its spontaneous cure in many untreated patients have been attributed to the limited genetic repertoire of Borrelia, enabling the host to build up cross-reactive as well as clone-specific antibodies. Antibiotic treatment of Borrelia infections may cause a ...
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... Actually, it seems that no individual cell is persistently infected at all! In the persistent phase, at any one time, only around 1% of cells are productively infected – but it isn’t always the same 1%. If we sop up virions emitted from cells using antibodies – without affecting virus inside cells – ...
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... Method of Entry - The way or place in which organisms, including infectious agents, enter the host’s body. ...
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... Mediated by IgE binding to the high affinity IgE receptor on mast cells, basophils, and activated eosinophils. Results in degranulation when antigen (allergen) binds to the IgE. This releases mediators of “early phase” responses within a few minutes—changes in vascular permeability, smooth muscle co ...
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Innate immunity in the lung: how epithelial cells fight against

... exact mechanisms and molecules involved in this response were incompletely understood In the last decade much has been learnt about the mechanisms that mediate this © adaptive’ arm of the innate immune system Cells of the innate immune system, including phagocytes, dendritic cells and epithelial cel ...
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Adaptive Immunity from Prokaryotes to Eukaryotes
Adaptive Immunity from Prokaryotes to Eukaryotes

... Fig. 2. Schematic representation of innate and adaptive immune feature development in animals. All immune cells express nonspecific receptors, for example, pattern recognition receptors that recognize pathogen associated molecular patterns (PAMPs). Several clusters of innate receptors are conserved ...
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Innate immune system



The innate immune system, also known as the nonspecific immune system, is an important subsystem of the overall immune system that comprises the cells and mechanisms that defend the host from infection by other organisms. The cells of the innate system recognize and respond to pathogens in a generic way, but, unlike the adaptive immune system (which is found only in vertebrates), it does not confer long-lasting or protective immunity to the host. Innate immune systems provide immediate defense against infection, and are found in all classes of plant and animal life. They include both humoral immunity components and cell-mediated immunity components.The innate immune system is an evolutionarily older defense strategy, and is the dominant immune system found in plants, fungi, insects, and primitive multicellular organisms.The major functions of the vertebrate innate immune system include: Recruiting immune cells to sites of infection, through the production of chemical factors, including specialized chemical mediators, called cytokines Activation of the complement cascade to identify bacteria, activate cells, and promote clearance of antibody complexes or dead cells The identification and removal of foreign substances present in organs, tissues, the blood and lymph, by specialised white blood cells Activation of the adaptive immune system through a process known as antigen presentation Acting as a physical and chemical barrier to infectious agents.↑ ↑ ↑
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