Gene Section MAPK12 (mitogen activated protein kinase 12) -
... p38gamma phosphorylates the transciption factor MyoD, which results in a decrease in its transcriptional activity. p38gamma plays a cardinal role in blocking the premature differentiation of skeletal muscle stem cells, the satellite cells. Additionally, p38gamma regulates mitochondrial biogenesis an ...
... p38gamma phosphorylates the transciption factor MyoD, which results in a decrease in its transcriptional activity. p38gamma plays a cardinal role in blocking the premature differentiation of skeletal muscle stem cells, the satellite cells. Additionally, p38gamma regulates mitochondrial biogenesis an ...
Methods S1.
... (http://microrna.sanger.ac.uk/), the PicTar database (http://pictar.bio.nyu.edu/) and ...
... (http://microrna.sanger.ac.uk/), the PicTar database (http://pictar.bio.nyu.edu/) and ...
Biochem SG06
... build up of compounds that are not currently needed, helping the cell to maintain biological balance or _______________________. 4) Transport: Hemoglobin, a protein, carries ____________ through blood. 5) Storage: Protein in milk stores amino acids for use by mammals. 6) Regulation: Many * hormones ...
... build up of compounds that are not currently needed, helping the cell to maintain biological balance or _______________________. 4) Transport: Hemoglobin, a protein, carries ____________ through blood. 5) Storage: Protein in milk stores amino acids for use by mammals. 6) Regulation: Many * hormones ...
REGULATION OF PROTEIN SYNTHESIS I. Bacteria
... There is also a type of regulation (twocomponent) that is similar to phosphorylation regulation of enzymes: activation of a kinase (e.g. by osmotic change) phosphorylates a gene activator. ...
... There is also a type of regulation (twocomponent) that is similar to phosphorylation regulation of enzymes: activation of a kinase (e.g. by osmotic change) phosphorylates a gene activator. ...
Death or Damage of Dopamine neurons
... movement, cognition, learning, and mood, explaining the dementia and difficulty with motor control exhibited by patients with deficits in the production of this key neurotransmitter. The a-synuclein gene was one of the first to be implicated in this disease. It produces a protein that can, in certai ...
... movement, cognition, learning, and mood, explaining the dementia and difficulty with motor control exhibited by patients with deficits in the production of this key neurotransmitter. The a-synuclein gene was one of the first to be implicated in this disease. It produces a protein that can, in certai ...
Document
... Yeast two-hybrid system: a genetic assay for detecting protein-protein interactions Regulation of gene expression in yeast ...
... Yeast two-hybrid system: a genetic assay for detecting protein-protein interactions Regulation of gene expression in yeast ...
Influenza A H3N2 (A/Perth/16/2009) Hemagglutinin / HA
... Protein Construction: A DNA sequence encoding the Influenza A virus (A/Perth/16/2009 (H3N2)) hemagglutinin (ACS71642.1) (Met1-Lys519, with a mutation Tyr 108 Phe), was expressed with a polyhistidine tag at the C-terminus. ...
... Protein Construction: A DNA sequence encoding the Influenza A virus (A/Perth/16/2009 (H3N2)) hemagglutinin (ACS71642.1) (Met1-Lys519, with a mutation Tyr 108 Phe), was expressed with a polyhistidine tag at the C-terminus. ...
Lecture 3 Proteins and Disease Protein structure summary… Recap…
... • Most common malignancy in women • Estrogen receptors are over-expressed in around 70% of breast cancer cases, referred to as "ER-positive". • Constant growth of Breast cells ...
... • Most common malignancy in women • Estrogen receptors are over-expressed in around 70% of breast cancer cases, referred to as "ER-positive". • Constant growth of Breast cells ...
Gene Section EIF4A2 (eukaryotic translation initiation factor 4A, isoform 2)
... Yoshida S, Kaneita Y, Aoki Y, Seto M, Mori S, Moriyama M. Identification of heterologous translocation partner genes fused to the BCL6 gene in diffuse large B-cell lymphomas: 5'-RACE and LA - PCR analyses of biopsy samples. Oncogene. 1999 ...
... Yoshida S, Kaneita Y, Aoki Y, Seto M, Mori S, Moriyama M. Identification of heterologous translocation partner genes fused to the BCL6 gene in diffuse large B-cell lymphomas: 5'-RACE and LA - PCR analyses of biopsy samples. Oncogene. 1999 ...
Biological databases play a central role in bioinformatics.
... – broad biological goals, such as mitosis or purine metabolism, metabolism, that are accomplished by ordered assemblies of molecular functions ...
... – broad biological goals, such as mitosis or purine metabolism, metabolism, that are accomplished by ordered assemblies of molecular functions ...
Document
... Based on the cloning and amplification of identified ORFs into homologous (ideally used for bacterial and yeast proteins) or sometimes heterologous systems (insect cells which result in post-translational modifications similar to mammalian cells). A fusion tag (short peptide or protein domain that i ...
... Based on the cloning and amplification of identified ORFs into homologous (ideally used for bacterial and yeast proteins) or sometimes heterologous systems (insect cells which result in post-translational modifications similar to mammalian cells). A fusion tag (short peptide or protein domain that i ...
BioH From DNA to proteins
... May result in only one amino acid mistake – protein may still function correctly ...
... May result in only one amino acid mistake – protein may still function correctly ...
lab 10 - genetics
... • This allele is for a protein (blood antigen) on the outer surface of red blood cells ...
... • This allele is for a protein (blood antigen) on the outer surface of red blood cells ...
Final Presentations Abstract Booklet (4.3 Mb .pdf file)
... billion bases long, and transcribing the entirety of the DNA to get a duplicate of a small section is highly inefficient. To combat this, DNA contains specific sequences that work in conjunction with proteins to signal where to begin and end copying for a specific section. One such sequence of nucle ...
... billion bases long, and transcribing the entirety of the DNA to get a duplicate of a small section is highly inefficient. To combat this, DNA contains specific sequences that work in conjunction with proteins to signal where to begin and end copying for a specific section. One such sequence of nucle ...
Name Chapter 5: The Structure and Function of Large Biological
... Answer the following questions in complete sentences, in your own words. 1. What is a macromolecule? Name four classes of biological macromolecules. 2. What is the relationship between monomers and polymers? 3. Anabolic enzymes catalyze reactions called dehydration synthesis; catabolic enzymes catal ...
... Answer the following questions in complete sentences, in your own words. 1. What is a macromolecule? Name four classes of biological macromolecules. 2. What is the relationship between monomers and polymers? 3. Anabolic enzymes catalyze reactions called dehydration synthesis; catabolic enzymes catal ...
Document
... may prevent transcription factors and/or RNA polymerase from binding to the major groove of the DNA. Second, it may prevent RNA polymerase from forming an open complex, which is necessary to begin transcription. Third, it could prevent looping in the DNA, which may be necessary to activate transcrip ...
... may prevent transcription factors and/or RNA polymerase from binding to the major groove of the DNA. Second, it may prevent RNA polymerase from forming an open complex, which is necessary to begin transcription. Third, it could prevent looping in the DNA, which may be necessary to activate transcrip ...
S1.Describe how the tight packing of chromatin in a closed
... may prevent transcription factors and/or RNA polymerase from binding to the major groove of the DNA. Second, it may prevent RNA polymerase from forming an open complex, which is necessary to begin transcription. Third, it could prevent looping in the DNA, which may be necessary to activate transcrip ...
... may prevent transcription factors and/or RNA polymerase from binding to the major groove of the DNA. Second, it may prevent RNA polymerase from forming an open complex, which is necessary to begin transcription. Third, it could prevent looping in the DNA, which may be necessary to activate transcrip ...
Tutorial 6
... research here was done to reveal the relations ship between these proteins in mammalian spermatozoa. To determine the subcellular localization of MUPP1 and CaMKII in spermatozoa, freshly isolated epididymal mouse sperm were simultaneously probed with a rabbit anti-MUPP1 and a mouse anti-CaMKII ant ...
... research here was done to reveal the relations ship between these proteins in mammalian spermatozoa. To determine the subcellular localization of MUPP1 and CaMKII in spermatozoa, freshly isolated epididymal mouse sperm were simultaneously probed with a rabbit anti-MUPP1 and a mouse anti-CaMKII ant ...
Chemistry Comes Alive: Part B Classes of Compounds • Inorganic
... Fibrous and Globular Proteins • Globular (functional) proteins • Compact, spherical, water-soluble and sensitive to environmental changes • Specific functional regions (active sites) • Examples: antibodies, hormones, molecular chaperones, and enzymes ...
... Fibrous and Globular Proteins • Globular (functional) proteins • Compact, spherical, water-soluble and sensitive to environmental changes • Specific functional regions (active sites) • Examples: antibodies, hormones, molecular chaperones, and enzymes ...
Tumor Necrosis Factor alpha
... Description: TNF-alpha is a homotrimer with a subunit molecular mass of 17 kDa and that it plays a major role in growth regulation, differentiation, inflammation, viral replication, tumorigenesis, and autoimmune diseases; and in viral, bacterial, fungal, and parasitic infections. Besides inducing he ...
... Description: TNF-alpha is a homotrimer with a subunit molecular mass of 17 kDa and that it plays a major role in growth regulation, differentiation, inflammation, viral replication, tumorigenesis, and autoimmune diseases; and in viral, bacterial, fungal, and parasitic infections. Besides inducing he ...
WELCOME TO BIOLOGY 2002 - National Evolutionary Synthesis
... position 193 of the Mc1r gene: A. arose by a mutation in the beach mouse populations in response to a need for protection from predation. B. leads to the failure of melanocytes to make an MC1R protein. C. arose by a mutation, which increased in frequency because it was selectively advantageous in th ...
... position 193 of the Mc1r gene: A. arose by a mutation in the beach mouse populations in response to a need for protection from predation. B. leads to the failure of melanocytes to make an MC1R protein. C. arose by a mutation, which increased in frequency because it was selectively advantageous in th ...
C3G (G-9): sc-393836
... regulation of a wide variety of cellular processes. Ras signals in its GTP-bound form but is “turned off” when bound to GDP. When unregulated or constitutively turned on by mutations, Ras signaling contributes to malignant transformation. The switch between active and inactive Ras is controlled by G ...
... regulation of a wide variety of cellular processes. Ras signals in its GTP-bound form but is “turned off” when bound to GDP. When unregulated or constitutively turned on by mutations, Ras signaling contributes to malignant transformation. The switch between active and inactive Ras is controlled by G ...
Where do pumpkins come from?
... • Translational regulatory proteins – recognize sequences in mRNA and inhibit translation (sometimes at the start codon) • Antisense RNA – a RNA strand that is complementary to mRNA binds to the mRNA and keeps it from being translated ...
... • Translational regulatory proteins – recognize sequences in mRNA and inhibit translation (sometimes at the start codon) • Antisense RNA – a RNA strand that is complementary to mRNA binds to the mRNA and keeps it from being translated ...
ap® biology 2013 scoring guidelines
... Question 6 asks students to work with data about the contribution of cellular structures to specialized cellular functions. Students were presented with experimental observations about the relative amounts of specific organelles in three different cell types and asked to identify a likely function o ...
... Question 6 asks students to work with data about the contribution of cellular structures to specialized cellular functions. Students were presented with experimental observations about the relative amounts of specific organelles in three different cell types and asked to identify a likely function o ...
Protein moonlighting
Protein moonlighting (or gene sharing) is a phenomenon by which a protein can perform more than one function. Ancestral moonlighting proteins originally possessed a single function but through evolution, acquired additional functions. Many proteins that moonlight are enzymes; others are receptors, ion channels or chaperones. The most common primary function of moonlighting proteins is enzymatic catalysis, but these enzymes have acquired secondary non-enzymatic roles. Some examples of functions of moonlighting proteins secondary to catalysis include signal transduction, transcriptional regulation, apoptosis, motility, and structural.Protein moonlighting may occur widely in nature. Protein moonlighting through gene sharing differs from the use of a single gene to generate different proteins by alternative RNA splicing, DNA rearrangement, or post-translational processing. It is also different from multifunctionality of the protein, in which the protein has multiple domains, each serving a different function. Protein moonlighting by gene sharing means that a gene may acquire and maintain a second function without gene duplication and without loss of the primary function. Such genes are under two or more entirely different selective constraints.Various techniques have been used to reveal moonlighting functions in proteins. The detection of a protein in unexpected locations within cells, cell types, or tissues may suggest that a protein has a moonlighting function. Furthermore, sequence or structure homology of a protein may be used to infer both primary function as well as secondary moonlighting functions of a protein.The most well-studied examples of gene sharing are crystallins. These proteins, when expressed at low levels in many tissues function as enzymes, but when expressed at high levels in eye tissue, become densely packed and thus form lenses. While the recognition of gene sharing is relatively recent—the term was coined in 1988, after crystallins in chickens and ducks were found to be identical to separately identified enzymes—recent studies have found many examples throughout the living world. Joram Piatigorsky has suggested that many or all proteins exhibit gene sharing to some extent, and that gene sharing is a key aspect of molecular evolution. The genes encoding crystallins must maintain sequences for catalytic function and transparency maintenance function.Inappropriate moonlighting is a contributing factor in some genetic diseases, and moonlighting provides a possible mechanism by which bacteria may become resistant to antibiotics.