Drug Metabolism • Most metabolic products are less pharmacologically active
... 1. Oxidized (Fe3+) cytochrome P-450 combines with a drug substrate to form a binary complex. 2. NADPH donates an electron to the cytochrome P-450 reductase, which in turn reduces the oxidized cytochrome P-450-drug complex. 3. A second electron is introduced from NADPH via the same cytochrome P-450 r ...
... 1. Oxidized (Fe3+) cytochrome P-450 combines with a drug substrate to form a binary complex. 2. NADPH donates an electron to the cytochrome P-450 reductase, which in turn reduces the oxidized cytochrome P-450-drug complex. 3. A second electron is introduced from NADPH via the same cytochrome P-450 r ...
SYNTHESIS OF FATTY ACID Acetyl
... The formation of D12 and D15 double bonds is not possible in animals Animals cannot synthesize linoleic acid (18:2D9,12), linolenic acid (18:3D9,12,15), or arachidonic acid (20:4 D5,8,11,14), which are used in the synthesis of eicosanoid hormones – Prostaglandins – Leukotrienes These are called esse ...
... The formation of D12 and D15 double bonds is not possible in animals Animals cannot synthesize linoleic acid (18:2D9,12), linolenic acid (18:3D9,12,15), or arachidonic acid (20:4 D5,8,11,14), which are used in the synthesis of eicosanoid hormones – Prostaglandins – Leukotrienes These are called esse ...
The early evolution of biological energy conservation
... as ancient as water on Earth [42] in which Fe2+ in the Earth’s crust reduces water in hydrothermal systems to H2 [42,62], and CO2 to carbon compounds that leave the vent through the effluent. Lost City effluent contains about 1 mM methane of abiogenic origin [49,60,61]. This is important because the t ...
... as ancient as water on Earth [42] in which Fe2+ in the Earth’s crust reduces water in hydrothermal systems to H2 [42,62], and CO2 to carbon compounds that leave the vent through the effluent. Lost City effluent contains about 1 mM methane of abiogenic origin [49,60,61]. This is important because the t ...
2007 Exam 3 1. The goal of the oxidative phase of the pentose
... 46. A patient fasted for approximately 18 hours, then consumed a protein-only meal. What effect would this meal have on gluconeogenesis in the patient’s liver? a. Gluconeogenesis would stop since the patient consumed a meal. b. The dietary amino acids would be used as a starting material for glucone ...
... 46. A patient fasted for approximately 18 hours, then consumed a protein-only meal. What effect would this meal have on gluconeogenesis in the patient’s liver? a. Gluconeogenesis would stop since the patient consumed a meal. b. The dietary amino acids would be used as a starting material for glucone ...
Essential Biology Topic 3 File
... 88. Complete the table below with the functions of the structures of the mitochondrion. ...
... 88. Complete the table below with the functions of the structures of the mitochondrion. ...
biochemistry - Biology Notes Help
... Biochemistry is a branch of medical science that attempt to describe the structure, organization & functions of living matter in molecular terms. Biochemistry also the science concerned with the chemical constituents of living cells & with the reactions & processes ...
... Biochemistry is a branch of medical science that attempt to describe the structure, organization & functions of living matter in molecular terms. Biochemistry also the science concerned with the chemical constituents of living cells & with the reactions & processes ...
Drug Metabolism
... • Products are generally more water soluble • These reactions products are ready for (renal) excretion • There are many complementary, sequential and competing ...
... • Products are generally more water soluble • These reactions products are ready for (renal) excretion • There are many complementary, sequential and competing ...
Magnesium: Mineral Link to Energy
... of magnesium to the body’s key energy form, ATP, is unquestionable. The biochemical paths and energy systems impacted by magnesium are both numerous and startling. Many hundreds of studies have demonstrated the various ways that magnesium imparts a positive influence on the body’s energy. There are ...
... of magnesium to the body’s key energy form, ATP, is unquestionable. The biochemical paths and energy systems impacted by magnesium are both numerous and startling. Many hundreds of studies have demonstrated the various ways that magnesium imparts a positive influence on the body’s energy. There are ...
Warm-Up
... “sugar splitting” Believed to be ancient (early prokaryotes - no O2 available) Occurs in cytosol Partially oxidizes glucose (6C) to 2 pyruvates (3C) ...
... “sugar splitting” Believed to be ancient (early prokaryotes - no O2 available) Occurs in cytosol Partially oxidizes glucose (6C) to 2 pyruvates (3C) ...
fatty acids synthesis
... with elongation.[Note: Humans lack the ability to introduce double bonds at carbon 9 therefore, must have the polyunsaturated linoleic and linolenic acids provided in the diet . Storage of fatty acids as components of triacylglycerols Mono-, di-, and triacylglycerols consist of one, two, or three mo ...
... with elongation.[Note: Humans lack the ability to introduce double bonds at carbon 9 therefore, must have the polyunsaturated linoleic and linolenic acids provided in the diet . Storage of fatty acids as components of triacylglycerols Mono-, di-, and triacylglycerols consist of one, two, or three mo ...
Lab 7 - Creighton Biology
... the sample. If it is less than 0.4 g ask for some additional tissue; if more, use a razor blade to remove some tissue. 2. Mince each muscle sample using a razor blade and petri dish. This step makes the homogenization more effective. 3. Place each sample in a small test tube with roughly ten times i ...
... the sample. If it is less than 0.4 g ask for some additional tissue; if more, use a razor blade to remove some tissue. 2. Mince each muscle sample using a razor blade and petri dish. This step makes the homogenization more effective. 3. Place each sample in a small test tube with roughly ten times i ...
Chapter 9 from Mrs Chou
... “sugar splitting” Believed to be ancient (early prokaryotes - no O2 available) Occurs in cytosol Partially oxidizes glucose (6C) to 2 pyruvates (3C) ...
... “sugar splitting” Believed to be ancient (early prokaryotes - no O2 available) Occurs in cytosol Partially oxidizes glucose (6C) to 2 pyruvates (3C) ...
Metabolic Flux Profiling of Reaction Modules in Liver Drug
... metabolite uptake or output) taken from previously published work. These studies profiled the metabolism of cultured hepatocytes under medium conditions that set up either a fed or fasted state. All data sets included time series measurements on glucose, lactate, ketone bodies, ammonia, and the natu ...
... metabolite uptake or output) taken from previously published work. These studies profiled the metabolism of cultured hepatocytes under medium conditions that set up either a fed or fasted state. All data sets included time series measurements on glucose, lactate, ketone bodies, ammonia, and the natu ...
Organic and Bio Chemistry 16
... 1. Enzymes: are proteins capable of acting as catalysts for biologic reactions. They may be simple or complex & may require cofactors or coenzymes for biologic activity. a. An enzyme enhances the rate of a specific chemical reaction by lowering the activation energy of the reaction. It does not chan ...
... 1. Enzymes: are proteins capable of acting as catalysts for biologic reactions. They may be simple or complex & may require cofactors or coenzymes for biologic activity. a. An enzyme enhances the rate of a specific chemical reaction by lowering the activation energy of the reaction. It does not chan ...
lecture CH23 chem131pikul
... form succinate, releasing energy that converts GDP to GTP. • Step [6] succinate is converted to fumarate with FAD and succinate dehydrogenase; FADH2 is formed. • Step [7], water is added across the C=C; this transforms fumarate into malate, which has a 2o alcohol. • Step [8], the 2o alcohol of malat ...
... form succinate, releasing energy that converts GDP to GTP. • Step [6] succinate is converted to fumarate with FAD and succinate dehydrogenase; FADH2 is formed. • Step [7], water is added across the C=C; this transforms fumarate into malate, which has a 2o alcohol. • Step [8], the 2o alcohol of malat ...
Ch 9 (primary ppt) - Phillips Scientific Methods
... 2. Where in the cell does glycolysis occur? 3. What are the reactants and products of glycolysis? ...
... 2. Where in the cell does glycolysis occur? 3. What are the reactants and products of glycolysis? ...
Fatty acid composition of some common oils and fats from plant
... decarboxylated malonyl esters contributing 2C each 2) Saturated fatty acids of between 12 and 20 C are common; overall shape is straight-chain ...
... decarboxylated malonyl esters contributing 2C each 2) Saturated fatty acids of between 12 and 20 C are common; overall shape is straight-chain ...
Chapter 9 – Cellular Respiration: Harvesting Chemical Energy
... When methane reacts with oxygen to form carbon dioxide, electrons end up farther away from the carbon atom and closer to their new covalent partners, the oxygen atoms, which are very electronegative. ...
... When methane reacts with oxygen to form carbon dioxide, electrons end up farther away from the carbon atom and closer to their new covalent partners, the oxygen atoms, which are very electronegative. ...
2.3 Carbon-Based Molecules
... 2.3 Carbon-Based Molecules • Carbohydrates can be broken down to provide energy for cells. • Some carbohydrates are part of cell structure. Polymer (starch) Starch is a polymer of glucose monomers that often has a branched structure. ...
... 2.3 Carbon-Based Molecules • Carbohydrates can be broken down to provide energy for cells. • Some carbohydrates are part of cell structure. Polymer (starch) Starch is a polymer of glucose monomers that often has a branched structure. ...
Cellular Respiration - Parkway C-2
... glucose is broken into 2 glyceraldehyde 3-phosphates (a 3-carbon compound) “investing” 2 ATP. These are converted into two molecules of pyruvic acid and the ‘investment’ pays out a total of 4 ATP and 2 NADH. The process of glycolysis produces and then captures two pairs of high-energy electrons usin ...
... glucose is broken into 2 glyceraldehyde 3-phosphates (a 3-carbon compound) “investing” 2 ATP. These are converted into two molecules of pyruvic acid and the ‘investment’ pays out a total of 4 ATP and 2 NADH. The process of glycolysis produces and then captures two pairs of high-energy electrons usin ...
chapter 9 cellular respiration: harvesting chemical
... Food is the fuel for respiration. The exhaust is carbon dioxide and water. The overall process is: organic compounds + O2 CO2 + H2O + energy (ATP + heat). Carbohydrates, fats, and proteins can all be used as the fuel, but it is most useful to consider glucose. C6H12O6 + 6O2 6CO2 + 6H2O ...
... Food is the fuel for respiration. The exhaust is carbon dioxide and water. The overall process is: organic compounds + O2 CO2 + H2O + energy (ATP + heat). Carbohydrates, fats, and proteins can all be used as the fuel, but it is most useful to consider glucose. C6H12O6 + 6O2 6CO2 + 6H2O ...
09_DetailLectOut_jkAR
... Food is the fuel for respiration. The exhaust is carbon dioxide and water. ...
... Food is the fuel for respiration. The exhaust is carbon dioxide and water. ...
respiration - SchoolRack
... How the process of chemiosmosis utilizes the electrons from NADH and FADH2 to produce ATP. ...
... How the process of chemiosmosis utilizes the electrons from NADH and FADH2 to produce ATP. ...
Basal metabolic rate
Basal metabolic rate (BMR) is the minimal rate of energy expenditure per unit time by endothermic animals at rest. (McNab, B. K. 1997). On the Utility of Uniformity in the Definition of Basal Rate of Metabolism. Physiol. Zool. Vol.70; Metabolism refers to the processes that the body needs to function. Basal Metabolic Rate is the amount of energy expressed in calories that a person needs to keep the body functioning at rest. Some of those processes are breathing, blood circulation, controlling body temperature, cell growth, brain and nerve function, and contraction of muscles. Basal metabolic rate (BMR) affects the rate that a person burns calories and ultimately whether you maintain, gain, or lose weight. Your basal metabolic rate accounts for about 60 to 75% of the calories you burn every day. It is influenced by several factors.