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Lec 15: Nitrogen in biochemistry
Lec 15: Nitrogen in biochemistry

... direct utilization is limited to few organisms (for  example Rhizobium living around roots of legume  plants). The organisms that fix N2 are called  Diazatrophs Therefore most other organisms rely on these N2‐ fixing microbes to generate NH3 ...
Application of Hard-Soft Acid-Base
Application of Hard-Soft Acid-Base

Option D Evolution - A - Origin of Life
Option D Evolution - A - Origin of Life

... extinct. Methane and iron would have been the sources of nutrients. Exogenesis - primitive life may have originally formed extraterrestrially, either in space or on a nearby planet (Mars). Panspermia - is the hypothesis that "seeds" of life exist already all over the Universe, that life on Earth may ...
LP - Columbia University
LP - Columbia University

... PROTEINS. These are the most important class of macromolecules in the cell, and we will discuss them now in detail. The monomers that make up proteins are the amino acids, of which there are 20. The same 20 in E. coli and in elephants and eggplant.   The general structure of an amino acid is: Note t ...
Biomolecules
Biomolecules

... Amino acids contain amino (–NH2) and carboxyl (–COOH) functional groups. Depending upon the relative position of amino group with respect to carboxyl group, the amino acids can be R CH COOH classified as α, β, γ, δ and so on. Only α-amino acids are obtained on hydrolysis of proteins. They NH2 may co ...
Bio Chem webquest
Bio Chem webquest

... 19. What is glucose and why is it so biologically important? 20. What is cellulose? Where can it be found? Is it a mono, di, or polysaccharide? 21. What is chitin? How is it similar, and different, from cellulose? ...
P site - Industrial ISD
P site - Industrial ISD

... pair of complimentary nucleotides with another nucleotide pair is called a base-pair substitution. • Some base-pair substitutions have little or no impact on protein function. • In silent mutations, alterations of nucleotides still indicate the same amino acids because of redundancy in the genetic c ...
Organic Compounds
Organic Compounds

biomolecule ppt
biomolecule ppt

... LIPIDS (fats) ● Functions: o Lipids can be used to store energy for later use o Phospholipids are important parts of biological membranes ...
Chapter 5c
Chapter 5c

... NAD+ ETC ...
150-06 (8-10-96) RNA world begins to add up
150-06 (8-10-96) RNA world begins to add up

... of the RNA world hypothesis, a scenario in which life began with RNA and later added DNA and proteins to its repertoire, are therefore seeking to create self-replicating RNA molecules to mirror those with which life on Earth might have originated. To self-replicate, an RNA strand would need to strin ...
Proteins and Electrophoresis
Proteins and Electrophoresis

Active site amino acid sequence of the bovine O6
Active site amino acid sequence of the bovine O6

... Tissue debris was then removed by centrifugation at 3200 Xg for 30 min. To 41 supernatant was added a thick slurry of 1.21 DE52 in buffer A (50mM NaCl, 20mM Tris HC1 pH 7.5, lmM K 2 HPO 4 , lmM EDTA, lmM dithiothreitol, 0.1% |3mercaptoethanol). The mixture was stirred for 30min and the DE52 allowed ...
Document
Document

... result in the production of unusual proteins as introns may still be present in some of the RNAs, and code for additional amino acids or aberrant terminations. c) Normally, a cell only exports mature or fully processed mRNA out of the nucleus. However, we learned in lecture that HIV can co-opt the c ...
Lecture_4_Glycolysis
Lecture_4_Glycolysis

Immunosuppressive drugs: the first 50 years and a glance forward
Immunosuppressive drugs: the first 50 years and a glance forward

Biochemistry I: Macromolecules
Biochemistry I: Macromolecules

... Overall, a molecule is held together by many interactions. A molecule forms a particular shape because it likes to adopt the lowest energy state (minimize entropy) In adopting this shape, the alternative conformations are selected, and the groups that cannot form hydrogen bonds with water (the hydro ...
Chapter 1 • Lesson 4 Objectives 4
Chapter 1 • Lesson 4 Objectives 4

... enzymes that catalyze different chemical reactions. All these cells are alike in some ways. For example, they all have some of the same enzymes, such as those that catalyze the breakdown of glucose to release energy. However, some enzymes are found only in certain kinds of cells. Your nerve cells, f ...
Working With Enzymes - Southern Biological
Working With Enzymes - Southern Biological

1. Fatty acids are broken down by the ß
1. Fatty acids are broken down by the ß

... Carnitine acyltransferase I is inhibited by malonyl CoA, preventing the breakdown of freshly synthesized fatty acids. ...
(NEU1) gene in two patients of sialidosis in India
(NEU1) gene in two patients of sialidosis in India

... neuraminidase-1 molecule. It has been hypothesized that the surface of the neuraminidase-1 molecule, where these amino acids are located, functions as a binding site between sialidase and PPCA (protective ...
Mock exam preparation chapters 1-8
Mock exam preparation chapters 1-8

... cells, carbon, hydrogen, oxygen Know the basic building blocks of life, lipids, proteins, and carbohydrates. Know how to test for each of these. Recognise monosacharides and polysacharides. Understand the importance of the peptide bond in joining amino acids. Understand the importance of water for l ...
Document
Document

Amino Acids: An Introduction to Their Structure, Functions and
Amino Acids: An Introduction to Their Structure, Functions and

Amino Acids as Acids, Bases and Buffers
Amino Acids as Acids, Bases and Buffers

... o Cereals are deficient in Lys o Legumes are low in Met and Cys o So vegetarians need variety - Since human cannot make all 20 aa’s – we are susceptible to protein malnutrition especially in children and elderly adults - Disorder called Kwashiorkor § Protein disorder in children § Prevalent in ove ...
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Biosynthesis



Biosynthesis (also called biogenesis or anabolism) is a multi-step, enzyme-catalyzed process where substrates are converted into more complex products in living organisms. In biosynthesis, simple compounds are modified, converted into other compounds, or joined together to form macromolecules. This process often consists of metabolic pathways. Some of these biosynthetic pathways are located within a single cellular organelle, while others involve enzymes that are located within multiple cellular organelles. Examples of these biosynthetic pathways include the production of lipid membrane components and nucleotides.The prerequisite elements for biosynthesis include: precursor compounds, chemical energy (e.g. ATP), and catalytic enzymes which may require coenzymes (e.g.NADH, NADPH). These elements create monomers, the building blocks for macromolecules. Some important biological macromolecules include: proteins, which are composed of amino acid monomers joined via peptide bonds, and DNA molecules, which are composed of nucleotides joined via phosphodiester bonds.
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