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22. Think of two different proteins: both are enzymes. a) What
22. Think of two different proteins: both are enzymes. a) What

... 22. Think of two different proteins: both are enzymes. a) What landmark (feature) of conformation (overall structure) will be found in both enzymes? (Name it and tell its function). Active sites for binding substrates to catalyze chemical reactions. b) If one of the enzymes is an allosteric protein, ...
Previous lecture: Today:
Previous lecture: Today:

... barrier called the free energy of activation ∆G‡ •Transition state is the unstable (10-13 seconds) highest energy species on the reaction coordinate •Enzymes lower the energy of activation barrier by lowering the energy of the transition state (stabilization) to allow for transformation to occur •Th ...
DNACompress
DNACompress

... • Simple: BioLZMA based on existing compression techniques like Huffman coding and LZMA compression. It's easy to implement. • Modularity: BioLZMA consists of several encoding subprocedures. These procedures can be replaced or reconfiguration for each compression process in order to achieve better p ...
purification and properties of glutamate dehydrogenase from the
purification and properties of glutamate dehydrogenase from the

Suppl. Table S3
Suppl. Table S3

... Transfer of a geranylgeranyl moeiety to Rab proteins ...
Semester 3 - Kurukshetra University
Semester 3 - Kurukshetra University

... questions from the entire syllabus, will be compulsory. The remaining six questions will be set taking three questions from each unit. The candidates will be required to attempt Q.No.1 & four others selecting two questions from each unit. All questions carry equal marks. UNIT-1 Enzymes: Historical p ...
Sample Chapter 5: Amino Acids, Peptides, and Proteins
Sample Chapter 5: Amino Acids, Peptides, and Proteins

... Because the sequence of amino acids determines the final three-dimensional configuration of each protein, their structures are examined carefully in the next four subsections. Amino acids are classified according to their capacity to interact with water. By using this criterion, four classes may be ...
Cell Respiration
Cell Respiration

... • A series of 10 biochemical reactions which begins and ends (cyclic) with a molecule of citric acid • Each acetic acid (2 carbons) is combined with a molecule of oxaloacetic acid in the mitochondrial matrix (4 carbons) to make citric acid (6 carbons) during step 1 • Each citric acid is then decarbo ...
Structure of LEP100, a Glycoprotein That Shuttles between
Structure of LEP100, a Glycoprotein That Shuttles between

... microsomes by immune precipitation followed by SDSPAGE (see Materials and Methods). The NH2-terminal amino acid sequence of LEP100, determined by sequential automated Edman degradation and product analysis, was PheAspValArgAspSefrhrGlyLysValCysIleIleAlaXLeuThrValAlaPheSerValGluTyrLysXXGlyGlnLys. Pos ...
Student Version
Student Version

... Anaerobic Respiration – works through the cellular respiration pathway (Glycolysis)  Fermentation – follows a similar format but ends with the production of an alcohol which cannot be transformed back. ...
File - Mr. Shanks` Class
File - Mr. Shanks` Class

... a) decreasing the temperature by 5C and keeping the pH at 8. b) increasing the temperature by 5C and keeping the pH at 8. c) maintaining the temperature at 30C and increasing the pH to 9. d) maintaining the temperature at 30C and decreasing the pH to 7. 9. What is the function of the allosteric ...
Document
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...  Thromboxane is a member of the family of lipids known as eicosanoids. The two major thromboxanes are thromboxane A2 and thromboxane B2. The distinguishing feature of thromboxanes is a 6membered ether-containing ring. ...
Is skin irritancy of the hand wash products solely related to their pH?
Is skin irritancy of the hand wash products solely related to their pH?

... other factors that contribute to the skin irritation of these products? The circumstances surrounding the development of dermatitis are complex but do not involve any immunological mechanism.1 The level of skin irritation is generally linked to numerous factors such as the chemical structure of comp ...
Chapter 25
Chapter 25

... reduced coenzymes NADH + H+ and FADH2, containing ________________ GTP, which ___________ to make ATP CO2  bloodstream and ________ at lungs ...
Mfold
Mfold

... structure for an RNA or DNA molecule depends on the model of folding and the specific folding energies used to calculate that structure. Different optimal foldings may be calculated if the folding energies are changed even slightly. Because of uncertainties in the folding model and the folding energ ...
PDF Fulltext
PDF Fulltext

... secondary free radical, which further can act as second messenger or can directly react with other biomolecule, enhancing biochemical lesions. Lipid peroxidation occurs on polysaturated fatty acid located on the cell membranes and it further proceeds with radical chain reaction. Hydroxyl radical is ...
Schuenemann_Cytochrome P450
Schuenemann_Cytochrome P450

... oxidation, and N- and O-dealkylation, by transfer of an active oxygen atom from its heme unit to the substrates. All enzymes of the cytochrome P450 family have a hydrophobic binding pocket, in which resides a protoporphyrine IX with its iron center being coordinated to an axial cysteine ligand [1]. ...
Metabolism Fansler
Metabolism Fansler

... • greatest number of molecular collisions – Heat: increase beyond optimum T° • increased energy level of molecules disrupts bonds in enzyme & between enzyme & substrate ...
Chapter 3
Chapter 3

Computational Geometry of Molecular Structure
Computational Geometry of Molecular Structure

The Citric acid cycle
The Citric acid cycle

09_Lecture
09_Lecture

... • Only substances whose concentrations change appear in an equilibrium expression. • Solids (s) and pure liquids (l) have constant concentrations so do not appear in the equilibrium expression. • If K is equal to 1, the ratio of products:reactants is 1:1 or [products] = [reactants]. • A value of K g ...
Triphosphatase Related to the Protein Tyrosine Phosphatases
Triphosphatase Related to the Protein Tyrosine Phosphatases

Cell Respiration State that oxidation involves the loss of electrons
Cell Respiration State that oxidation involves the loss of electrons

... molecules of ATP are produced when two molecules of pyruvate are formed. Coupled with the loss of two ATP molecules in phosphorylation, the net gain of ATP in glycolysis is two. The triose phosphate is oxidised to form pyruvic acid. The phosphate is donated to ADP to form the ATP. Pyruvic acid is al ...
biochem
biochem

... the rate of formation of glucose by gluconeogenesis. What is one of the mechanisms behind this? • A. Increased NADH • B. Increased NADPH • C. Increased FADH2 • D. Decreased Biotin • E. Inactivation of pyruvate carboxylase ...
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Biosynthesis



Biosynthesis (also called biogenesis or anabolism) is a multi-step, enzyme-catalyzed process where substrates are converted into more complex products in living organisms. In biosynthesis, simple compounds are modified, converted into other compounds, or joined together to form macromolecules. This process often consists of metabolic pathways. Some of these biosynthetic pathways are located within a single cellular organelle, while others involve enzymes that are located within multiple cellular organelles. Examples of these biosynthetic pathways include the production of lipid membrane components and nucleotides.The prerequisite elements for biosynthesis include: precursor compounds, chemical energy (e.g. ATP), and catalytic enzymes which may require coenzymes (e.g.NADH, NADPH). These elements create monomers, the building blocks for macromolecules. Some important biological macromolecules include: proteins, which are composed of amino acid monomers joined via peptide bonds, and DNA molecules, which are composed of nucleotides joined via phosphodiester bonds.
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