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chapt05_lecture
chapt05_lecture

... a. Fat stored in adipose tissue as triglycerides b. Great way to store energy: 1 gram fat = 9 kcal energy. 1) In a nonobese 155-pound man, 80-85% of his stored energy is in fat. (140,000 calories) c. Lipolysis: breaking triglycerides down into fatty acids and glycerol using the enzyme lipase. 1) Fat ...
Combinatorial chemistry: A novel method in drug discovery and its
Combinatorial chemistry: A novel method in drug discovery and its

... regenerating certain functional groups in a reaction sequence. Some examples of the protecting groups are as follows. Fmoc (Fluoromethoxy carbonyl benzyl ester) and Boc (Tertiarybutyloxy carbonyl). Two distinct mechanisms for elaborating molecular diversity may be defined by (i) parallel synthesis a ...
LecturesPart07
LecturesPart07

... For each position in the set, find the most common amino acid observed there Calculate the frequency with which each other amino acid is observed at that position Combine frequencies from all positions to give table showing frequencies for each amino acid changing to each other amino acid Take logar ...
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to the PDF file. - CURVE

... Resistance to, metronidazole and tinidazole, the drugs currently prescribed for the treatment of trichomoniasis, an infection of the genito-urinary tract of humans by the protozoan Trichomonas vaginalis, has created a need for the development of therapeutics with a different mode of action. Trifluor ...
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... 1) primary structure – sequence of amino acids 2) secondary structure – small units of repetitive structure 3) tertiary structure – overall 3D shape 4) quaternary structure – shape of ≥2 chains ...
Genetics Test 3 Review Presentation
Genetics Test 3 Review Presentation

... • Viruses that have an RNA core rather than a DNA core. • Retroviruses replicate in an unusual way • The RNA serves as a template for synthesis of a complementary DNA by the RNA-dependent DNA polymerase reverse transcriptase. • This DNA can be incorporated into the host cell genome; when transcribed ...
Primary Sequence of Ovomucoid Messenger RNA as Determined
Primary Sequence of Ovomucoid Messenger RNA as Determined

... from a partially purified preparation of mRNA om by polymerization by reverse transcriptase in the presence of a restriction fragment primer from pOM100 . The complementary DNA mixture was amplified by molecular cloning using poly dG/dC tailing to form recombinant bacterial plasmids . Recombinant pl ...
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Carbohydrate metabolism File

... • Regulation of glycogenesis and glycogenolysis: Cyclic AMP (Fig.2.4.) integrates the regulation of glycogenolysis and glycogenesis. The principal enzymes controlling glycogen metabolism glycogen phosphorylase and glycogen synthase are regulated by a complex series of reactions involving both allos ...
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... -Blue cheese: penicillin spores are mixed with the curds blue -Swiss Cheese: holes from the ...
8)Discuss the roles of cofactors and coenzymes in enzyme activity.
8)Discuss the roles of cofactors and coenzymes in enzyme activity.

... hydroxyl group of serine, sulfhydryl group of cysteine; to which substrate can covalently bind. 5. Structural flexibility: In order to bind the substrates appropriately, some enzymes change their configuration to provide a better orientation of the substrate (induced-fit hypothesis) so that enzyme c ...
Plants
Plants

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Kinetics of Enzyme-Catalyzed Reactions
Kinetics of Enzyme-Catalyzed Reactions

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Chapter 7 Carbohydrates: Nomenclature Monosaccharides
Chapter 7 Carbohydrates: Nomenclature Monosaccharides

... pyranose ring form, while fructose, a keto hexose, is found in the furanose ring form, and ribose, an aldopentose, is found in the furanose ring form. The free sugars can exist as a mixture of ring forms, but the structures we encounter as metabolic intermediates are usually bound to phosphate and t ...
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complex I

... - contains a variety of transport proteins that make it selectively permeable to those small molecules that are metabolized or required by the many mitochondrial enzymes concentrated in the matrix. - enzymes of the respiratory chain, are essential to the process of oxidative phosphorylation, which g ...
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... • Whereas the primary structure of a protein is determined by the covalently linked amino acid residues in the polypeptide backbone, secondary and higher orders of structure are determined principally by noncovalent forces such as hydrogen bonds and ionic, van der Waals, and hydrophobic interaction ...
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cellular respiration

... -use of inorganic molecules (other than O2) as final electron acceptor 2. fermentation -use of organic molecules as final electron acceptor ...
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... Nicotinic Acid- Decrease uptake of VLDL remnants (aka niacin) - Inc LDL receptor synthesis, therefore decreasing blood cholesterol. - dyslipidemia lecture: niacin inhibits lipase of fatty acids - lowers LDL and TG, while increasing HDL - was the first dyslipidemia treatment (1950’s) ...
The peptide bond is rigid and planar
The peptide bond is rigid and planar

Introduction to 3D-Structure Visualization and Homology Modeling
Introduction to 3D-Structure Visualization and Homology Modeling

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... Carnitine-mediated transfer of the fatty acyl moiety into the mitochondrial matrix is a 3-step process: 1. Carnitine Palmitoyl Transferase I, an enzyme on the cytosolic surface of the outer mitochondrial membrane, transfers a fatty acid from CoA to the OH on carnitine. 2. An antiporter in the inner ...
Campbell`s Biology, 9e (Reece et al.) Chapter 8 An
Campbell`s Biology, 9e (Reece et al.) Chapter 8 An

... C) binds noncompetitive inhibitors of the enzyme. D) is inhibited by the presence of a coenzyme or a cofactor. Answer: B Topic: Concept 8.4 Skill: Knowledge/Comprehension 37) According to the induced fit hypothesis of enzyme catalysis, which of the following is correct? A) The binding of the substra ...
BIO 101 Worksheet Metabolism and Cellular Respiration
BIO 101 Worksheet Metabolism and Cellular Respiration

... 2. _______ An end product of glycolysis is pyruvate 3. _______ A 6 carbon sugar is oxidized in glycolysis 4. _______ CO2 is a waste product of glycolysis 5. _______ sugar + NAD+  pyruvate + NADH + 2 ATP represents glycolysis 6. _______ Glycolysis leads to fermentation in some bacteria and yeast 7. ...
Base excision repair
Base excision repair

... Exposure of cells to ionizing radiation or other double strand break-inducing agents triggers an increase in ATM kinase activity (a serine–threonine kinase in the nucleus). A kinase is a type of enzyme that transfers phosphate groups from high-energy donor molecules, such as ATP, to specific substra ...
study guide 009
study guide 009

... 4. Explain how ATP is recycled in cells. 5. What is a redox reaction? Define oxidation and reduction. 6. What is the name and function of the electron donor and the electron acceptor? 7. Explain how redox reactions are involved in energy exchanges. 8. Explain why organic molecules that have an abund ...
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Biosynthesis



Biosynthesis (also called biogenesis or anabolism) is a multi-step, enzyme-catalyzed process where substrates are converted into more complex products in living organisms. In biosynthesis, simple compounds are modified, converted into other compounds, or joined together to form macromolecules. This process often consists of metabolic pathways. Some of these biosynthetic pathways are located within a single cellular organelle, while others involve enzymes that are located within multiple cellular organelles. Examples of these biosynthetic pathways include the production of lipid membrane components and nucleotides.The prerequisite elements for biosynthesis include: precursor compounds, chemical energy (e.g. ATP), and catalytic enzymes which may require coenzymes (e.g.NADH, NADPH). These elements create monomers, the building blocks for macromolecules. Some important biological macromolecules include: proteins, which are composed of amino acid monomers joined via peptide bonds, and DNA molecules, which are composed of nucleotides joined via phosphodiester bonds.
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