A structural comparison of molybdenum cofactor
... transhydroxylase, most of these enzymes serve as terminal reductases in the absence of oxygen and the presence of their respective substrates, thereby allowing the bacteria to generate more energy compared to the amount obtainable by fermentation. DMSO reductase is found in a variety of bacteria, in ...
... transhydroxylase, most of these enzymes serve as terminal reductases in the absence of oxygen and the presence of their respective substrates, thereby allowing the bacteria to generate more energy compared to the amount obtainable by fermentation. DMSO reductase is found in a variety of bacteria, in ...
No Slide Title
... • Where the metabolite is more active (Prodrugs, e.g. Erythromycin-succinate (less irritation of GI) --> Erythromycin) ...
... • Where the metabolite is more active (Prodrugs, e.g. Erythromycin-succinate (less irritation of GI) --> Erythromycin) ...
Drug Metabolism • Most metabolic products are less pharmacologically active
... • Where the metabolite is more active (Prodrugs, e.g. Erythromycin-succinate (less irritation of GI) --> Erythromycin) ...
... • Where the metabolite is more active (Prodrugs, e.g. Erythromycin-succinate (less irritation of GI) --> Erythromycin) ...
Lab5
... type of energy metabolism it uses, what substrates it utilizes to build new materials and which hydrolytic enzymes it has to breakdown materials into smaller, more useable pieces. We also can use combination media that contain several of these tests in one. These biochemical tests are all done on di ...
... type of energy metabolism it uses, what substrates it utilizes to build new materials and which hydrolytic enzymes it has to breakdown materials into smaller, more useable pieces. We also can use combination media that contain several of these tests in one. These biochemical tests are all done on di ...
Pyruvate Dehydrogenase
... •We’ve now lost 2 CO2 in Krebs + 1 in PDH – glucose is gone. •The two carbons we’ve lost are not the same ones we brought in. ...
... •We’ve now lost 2 CO2 in Krebs + 1 in PDH – glucose is gone. •The two carbons we’ve lost are not the same ones we brought in. ...
Chapter 4 - Jenkins Independent Schools
... energy level, so it can form covalent bonds with as many as four other atoms. When carbon atoms form covalent bonds, they obtain the stability of a noble gas with eight electrons in their outer energy level. One of carbon’s most frequent partners in forming covalent bonds is hydrogen. Substances can ...
... energy level, so it can form covalent bonds with as many as four other atoms. When carbon atoms form covalent bonds, they obtain the stability of a noble gas with eight electrons in their outer energy level. One of carbon’s most frequent partners in forming covalent bonds is hydrogen. Substances can ...
One-Pot Asymmetric Synthesis of β-Cyanohydroxymethyl r
... of L-proline.3a Because of the aldehyde functionality present in the product, the excellent diastereo- and enantioselectivities of the reaction, and the mild reaction conditions provided by L-proline catalysis,4 the products should be useful for the further transformations such as nucleophilic react ...
... of L-proline.3a Because of the aldehyde functionality present in the product, the excellent diastereo- and enantioselectivities of the reaction, and the mild reaction conditions provided by L-proline catalysis,4 the products should be useful for the further transformations such as nucleophilic react ...
Chapter 2 3EPchanges
... b. Define: monomers, polymers, and macromolecule c. What is the importance of carbon in forming macromolecules and/or organic compounds? d. Define and draw out the processes of dehydration synthesis and hydrolysis with an example of a ...
... b. Define: monomers, polymers, and macromolecule c. What is the importance of carbon in forming macromolecules and/or organic compounds? d. Define and draw out the processes of dehydration synthesis and hydrolysis with an example of a ...
The pyruvate dehydrogenase complex of the chemol
... The pyruvate dehydrogenase (PDH) complex catalyses the oxidative decarboxylation of pyruvate generating acetyl-CoA and NADH, and releasing CO,, thereby providing a link between glycolysis and the Kreb's cycle. The reaction takes place in several steps. In the first, pyruvate decarboxylase converts p ...
... The pyruvate dehydrogenase (PDH) complex catalyses the oxidative decarboxylation of pyruvate generating acetyl-CoA and NADH, and releasing CO,, thereby providing a link between glycolysis and the Kreb's cycle. The reaction takes place in several steps. In the first, pyruvate decarboxylase converts p ...
Document
... to promote protein-protein interactions (i.e. for the Ras superfamily G-proteins). Prenyltranferases are enzymes catalyzing the addition of lipid moieties to proteins and are currently considered as potential targets in cancer therapy. Several candidate compounds targeting prenyltransferases show a ...
... to promote protein-protein interactions (i.e. for the Ras superfamily G-proteins). Prenyltranferases are enzymes catalyzing the addition of lipid moieties to proteins and are currently considered as potential targets in cancer therapy. Several candidate compounds targeting prenyltransferases show a ...
Molecular Abnormality of Erythrocyte Pyruvate
... deficiency. The probands had suffered from severe hemolytic anemia, and required transfusion every 8 weeks. After splenectomy the anemia was compensated, with a Hb level of about 9 to 10 g/dL. Cellular studies of the PK-deficient RBCs showed increased K' content and a markedly expanded ouabain-insen ...
... deficiency. The probands had suffered from severe hemolytic anemia, and required transfusion every 8 weeks. After splenectomy the anemia was compensated, with a Hb level of about 9 to 10 g/dL. Cellular studies of the PK-deficient RBCs showed increased K' content and a markedly expanded ouabain-insen ...
Aromatic Amino Acids-Guanidinium Complexes through
... hosts bind to cationic guests stronger than to neutral or charged molecules [2]. Moreover, they carried out a protein database assessment showing that cation-stabilization is fundamental in protein structure and function and that arginine (Arg) in particular is the residue that most often [3] binds. ...
... hosts bind to cationic guests stronger than to neutral or charged molecules [2]. Moreover, they carried out a protein database assessment showing that cation-stabilization is fundamental in protein structure and function and that arginine (Arg) in particular is the residue that most often [3] binds. ...
Metabolism and Biotransformation of Pesticides
... In many cases males and females of the same species differ in levels (or even presence) of P450 isozymes. Examples: aromatase, which catalyzes conversion of testosterone to estradiol. In the rat, it is present in the male testes and the female adrenal glands. As sperm matures, it Apparently require ...
... In many cases males and females of the same species differ in levels (or even presence) of P450 isozymes. Examples: aromatase, which catalyzes conversion of testosterone to estradiol. In the rat, it is present in the male testes and the female adrenal glands. As sperm matures, it Apparently require ...
Molecular Models for Biochemistry at CMU
... http://info.bio.cmu.edu/Courses/BiochemMols/BCMolecules.html ...
... http://info.bio.cmu.edu/Courses/BiochemMols/BCMolecules.html ...
Biosynthesis
Biosynthesis (also called biogenesis or anabolism) is a multi-step, enzyme-catalyzed process where substrates are converted into more complex products in living organisms. In biosynthesis, simple compounds are modified, converted into other compounds, or joined together to form macromolecules. This process often consists of metabolic pathways. Some of these biosynthetic pathways are located within a single cellular organelle, while others involve enzymes that are located within multiple cellular organelles. Examples of these biosynthetic pathways include the production of lipid membrane components and nucleotides.The prerequisite elements for biosynthesis include: precursor compounds, chemical energy (e.g. ATP), and catalytic enzymes which may require coenzymes (e.g.NADH, NADPH). These elements create monomers, the building blocks for macromolecules. Some important biological macromolecules include: proteins, which are composed of amino acid monomers joined via peptide bonds, and DNA molecules, which are composed of nucleotides joined via phosphodiester bonds.