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Microbial Metabolism
Microbial Metabolism

... In living cells, the enzyme-regulated chemical reactions that release energy are generally the ones involved in catabolism, the breakdown of complex organic compounds into simpler ones. These reactions are called catabolic, or degradative, reactions. Catabolic reactions are generally hydrolytic reac ...
Amino acid sequence and structural repeats in schistosome
Amino acid sequence and structural repeats in schistosome

Transcriptome profiling identifies candidate genes associated with
Transcriptome profiling identifies candidate genes associated with

Slides
Slides

... Increases the rate of chemical reaction / biological process Remains unchanged Biomolecules that catalyze chemical reactions Usually proteins ...
General Chemistry 110 Quiz 1
General Chemistry 110 Quiz 1

Section 5
Section 5

AlgPred: prediction of allergenic proteins and mapping of
AlgPred: prediction of allergenic proteins and mapping of

... severe reactions such as acute and fatal anaphylactic shock can also occur. It affects a large population with very high prevalence particularly of skin sensitization (4,5). Most allergic responses occur on mucous membrane surface in response to allergens that enter the body by either inhalations or ...
Protein synthesis (Primer)
Protein synthesis (Primer)

... Central Dogma of Molecular Biology states that information flow from DNA Î RNA Î protein DNA is made of phosphonucleotides (phosphoate + sugar + base) Genetic information is encoded in a string of DNA bases (A,C,G,T) Hydrogen bond mediated base pairing (A**T, C**G) protects DNA bases from chemical d ...
autonomic nervous system
autonomic nervous system

... peripheral nervous system that acts as a control system functioning largely below the level of consciousness, and controls visceral functions.[1] The ANS affects heart rate, digestion, respiration rate, salivation, perspiration, diameter of the pupils, micturition (urination), and sexual arousal. Wh ...
A Genetic Defect in Amino Acid Metabolism: Phenylketonuria (PKU)
A Genetic Defect in Amino Acid Metabolism: Phenylketonuria (PKU)

... phenylalanine cannot be broken-down and its level in blood gets very high. On the other hand, Tyrosine levels tend to be low. It consequences melanin cannot be formed. So, a child with PKU will have blonde hair and blue eyes. ...
Investigation of a Zα-like Peptide Motif in Koi Herpesvirus
Investigation of a Zα-like Peptide Motif in Koi Herpesvirus

... The CD spectra indicate that the Zα-like peptide motif of ORF112 does not exhibit sequence specificity or a B- to Z-DNA transition, like most Zα domains. However, it is affected by amino acid residue mutations that are significant in most Zα domains. The wild type protein showed inversion of bands f ...
A Mechanistic Analysis of Enzymatic Degradation - J
A Mechanistic Analysis of Enzymatic Degradation - J

... substrate, D- or L-2-chloropropionate, the major product was found to be 18 O-labeled lactate. Mass spectrometric analysis of the enzyme after a multiple turnover reaction in H2 18 O revealed that 18 O was not incorporated into the enzyme during the reaction. These results indicate that the solvent ...
this help page as PDF
this help page as PDF

... exons and introns and shows where discrepancies are located. It also shows the identifiers of the target sequences. In order not to make small exons vanish when very large intronic stretches are found, the scaling of introns end exons is automatically balanced to make the picture visually meaningful ...
The following equations and constants may be useful:
The following equations and constants may be useful:

... conversion does not change the number of non-polar buried residues and therefore the hydrophobic effect is of no importance in this problem. a) Assuming that each strand is 10 residues long, estimate the relative stability (i.e. ∆Go) of the two structures. Please state your assumptions (6 pts) ...
DESIGN AND SYNTHESIS OF TRIPHENYL-1H-PYRAZOLE DERIVATIVES AS ANTICANCER AGENTS
DESIGN AND SYNTHESIS OF TRIPHENYL-1H-PYRAZOLE DERIVATIVES AS ANTICANCER AGENTS

... protein preparation wizard tool (Glide), which performs the following steps: assigning of bond orders, addition of hydrogen, optimization of hydrogen bonds by flipping amino side chains, correction of charges, and minimization of the protein complex. All the bound water molecules, ligands and cofact ...
A-level Human Biology Question Paper Unit 04 - Bodies and
A-level Human Biology Question Paper Unit 04 - Bodies and

... There are two sites on the ribosome, Site 1 and Site 2. 3 (c) (i) ...
Lehninger Principles of Biochemistry 5/e
Lehninger Principles of Biochemistry 5/e

The Escherichia coli SlyD Is a Metal Ion-regulated Peptidyl
The Escherichia coli SlyD Is a Metal Ion-regulated Peptidyl

... Independently, the protein SlyD (there called WHP, wonderous histidine-rich protein) was discovered by binding to nickel ions immobilized on nitriloacetic acid-agarose (NTA) resin (9). Derived from the amino acid sequence, SlyD consists of two sequence regions, an N-terminal stretch of 146 amino aci ...
Biochemistry
Biochemistry

Surface complementarity of buried protein residues
Surface complementarity of buried protein residues

... homologous structures). In this context, the apolar residues constituting hydrophobic cores carry high informational content3. This is borne out by the fact that site-directed mutagenesis of these residues are generally destabilizing4,5 for the protein. Further sequence and structure comparison stud ...
Fructose-1,6 - LSU School of Medicine
Fructose-1,6 - LSU School of Medicine

(ATP). - WordPress.com
(ATP). - WordPress.com

... b Oxidation of Fatty Acids In stage 2 of fat metabolism, fatty acids undergo beta oxidation, which removes two carbon segments from carbonyl end.  Each cycle in oxidation produces acetyl CoA and a fatty acid that is shorter by two carbons. ...
Directions for Use Ready One-Step RT-PCR Kit
Directions for Use Ready One-Step RT-PCR Kit

The 92-kDa chitinase from Streptomyces olivaceoviridis contains a
The 92-kDa chitinase from Streptomyces olivaceoviridis contains a

... By the addition of the serine proteinase inhibitor Pefabloc SC during the purification procedure it was possible to prepare pure proteinases and the 92-kDa chitinase (single bands in SDSPAGE). It could be shown that the three proteinases have the same amino acid sequence at the N-terminus which is a ...
The following equations and constants may be useful:
The following equations and constants may be useful:

... conversion does not change the number of non-polar buried residues and therefore the hydrophobic effect is of no importance in this problem. a) Assuming that each strand is 10 residues long, estimate the relative stability (i.e. Go) of the two structures. Please state your assumptions (6 pts) ...
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Biosynthesis



Biosynthesis (also called biogenesis or anabolism) is a multi-step, enzyme-catalyzed process where substrates are converted into more complex products in living organisms. In biosynthesis, simple compounds are modified, converted into other compounds, or joined together to form macromolecules. This process often consists of metabolic pathways. Some of these biosynthetic pathways are located within a single cellular organelle, while others involve enzymes that are located within multiple cellular organelles. Examples of these biosynthetic pathways include the production of lipid membrane components and nucleotides.The prerequisite elements for biosynthesis include: precursor compounds, chemical energy (e.g. ATP), and catalytic enzymes which may require coenzymes (e.g.NADH, NADPH). These elements create monomers, the building blocks for macromolecules. Some important biological macromolecules include: proteins, which are composed of amino acid monomers joined via peptide bonds, and DNA molecules, which are composed of nucleotides joined via phosphodiester bonds.
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