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MD Simulations of the P53 oncoprotein structure
MD Simulations of the P53 oncoprotein structure

Enzymologychapter13 - Panama College of Cell Science
Enzymologychapter13 - Panama College of Cell Science

... Many enzymes carry out their catalytic function relying solely on their protein structure. Many others require nonprotein components, called cofactors (Table 13.2). Cofactors may be metal ions or organic molecules referred to as coenzymes. Coenzymes and cofactors provide proteins with chemically ver ...
Lactobacilli carry cryptic genes encoding peptidase
Lactobacilli carry cryptic genes encoding peptidase



... the most versatile amino acids in animal cells”. In fact Arg is required for the synthesis of several compounds, such as ornithine, polyamines, proline, creatine, proteins, nitric oxide (NO), and citrulline, besides glutamate and agmatine in mammals. Arg is also considered a powerful secretagogue, i ...
CHAPTER 6
CHAPTER 6

TIBS review article by Killian & Heijne
TIBS review article by Killian & Heijne

... Lys and Trp will be buried in the hydrophobic part of the bilayer. Molecular modeling indicates that when the Lys side chains in KALP23 ‘snorkel’ and extend upwards towards the aqueous phase, their positively charged NH3 group can reach a position approximately 3.4 Å further away from the bilayer ce ...
BIOCHEMISTRY
BIOCHEMISTRY

... Lipids $30 A triglyceride has how many glycerols and how many fatty acids? ...
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Recent advances in biosynthesis of fatty acids derived products in

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Some psychrophiles Abstract

... 73°C) indicated that the G+C contents of these microorganisms is similar [42]. Although the general opinion is that overall genomic G+C content cannot be used to distinguish between microbial thermal classes, some psychrophilic microorganisms contain distinctly high G+C genomic regions, which mainly ...
Carbohydrate Metabolism of Staphylococcus aureus
Carbohydrate Metabolism of Staphylococcus aureus

... For the preparation of cell-free extracts, suspensions of cocci were obtained as described. The cocci were washed twice in 0*8570NaCl solution and suspended in 0.01 M-phosphate buffer (pH 7-0). A suspension (15 mg. dry weightlml.) was mixed with twice its volume of ballotini (no. 11) and treated for ...
The effecTs of benzoic acid and proTein level on urine ph and
The effecTs of benzoic acid and proTein level on urine ph and

Directions for Use Uracil-DNA Glycosylase (UNG), Cod
Directions for Use Uracil-DNA Glycosylase (UNG), Cod

... (ung-) by a modified ung gene derived from Atlantic Cod. It degrades uracil-containing singleand double-stranded DNA, but not RNA or thymidine-containing DNA, by hydrolyzing the Nglycosidic bond between deoxyribose sugar and the base in uracil. This generates alkalinesensitive apyramidinic sites in ...
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Design and analysis of metabolic pathways supporting

... formate-dependent microbial electrosynthesis [43,46]. However, while remarkable progress was achieved in the genetic manipulation, metabolic engineering and bulk cultivation of these organisms, they are still less streamlined for industrial use as compared to model organisms, such as S. cerevisiae a ...
VITAMINS
VITAMINS

... acid residues present in the proteins and this reaction is catalysed by a carboxylase (microsomal). It involves the conversion of glutamate (Glu) to carboxyglutamate is inhibited by dicumarol, an anticoagulant found in spoilt sweet clover. Warfarin is a synthetic analogue that can inhibit vitamin K ...
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Chap 7 PP

... • If oxygen is not present to accept the ETC electrons, the entire energy-harvesting process downstream from glycolysis comes to a halt. ...
Treatment of inherited metabolic disorders
Treatment of inherited metabolic disorders

Answers to Problems in Text - pdf
Answers to Problems in Text - pdf

... the doubly occupied 2px orbital, whereas the electron removed from N is an electron from the singly occupied 2pz orbital. There is some repulsion between the two paired electrons in the case of oxygen, which means that it is easier to remove an electron from O than it is an electron from the singly ...
Elite Fuel® White Papers ©
Elite Fuel® White Papers ©

... into  ATP,  the  body's  energy  source.  Malic  acid  is  a  metabolite  in  the  Krebs  cycle,  which  is  responsible  for   the  biochemical  reactions  that  produce  90  percent  of  the  energy  in  the  cells  of  the  body. ...
1. Sources of cholesterol • diet ~ 30 % • biosynthesis ~ 70% 2. Types
1. Sources of cholesterol • diet ~ 30 % • biosynthesis ~ 70% 2. Types

Ontario`s Expanded Screening Program
Ontario`s Expanded Screening Program

A Metabolic Node in Action: Chorismate
A Metabolic Node in Action: Chorismate

Protein Metabolism and Acidosis
Protein Metabolism and Acidosis

... Protein degradation and synthesis is a continuous process that functions to eliminate abnormal proteins and to permit the regulation of cellular metabolism. The rate at which protein degradation occurs varies with both the nutritional and hormonal state of cells. One of the key determinants of prote ...
Human Physiology - Maryville University
Human Physiology - Maryville University

... Catabolism breaks down molecules & releases energy Is primary source of energy for making ATP Anabolism makes larger molecules & requires energy Source of body’s large energy-storage compounds ...
03-232 Biochemistry Exam II - 2013 Name:________________________
03-232 Biochemistry Exam II - 2013 Name:________________________

... If the energy of the transition state is lower, then there will be more of it, and a higher rate will occur. ii) The folding of the enzyme pre-orders the functional groups (aa sidechains) in the active site, so there is no unfavorable decrease in entropy. iii) The formation of hydrogen bonds to just ...
Week Date Hours Topic Standard IBO Assessment Statement Labs
Week Date Hours Topic Standard IBO Assessment Statement Labs

... in prokaryotes, including the role of the promoter region, RNA polymerase, nucleoside triphosphates and the terminator. State that eukaryotic RNA needs the removal of introns to form mature mRNA. Explain that each tRNA molecule is recognized by a tRNA-activating enzyme that binds a specific amino ac ...
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Biosynthesis



Biosynthesis (also called biogenesis or anabolism) is a multi-step, enzyme-catalyzed process where substrates are converted into more complex products in living organisms. In biosynthesis, simple compounds are modified, converted into other compounds, or joined together to form macromolecules. This process often consists of metabolic pathways. Some of these biosynthetic pathways are located within a single cellular organelle, while others involve enzymes that are located within multiple cellular organelles. Examples of these biosynthetic pathways include the production of lipid membrane components and nucleotides.The prerequisite elements for biosynthesis include: precursor compounds, chemical energy (e.g. ATP), and catalytic enzymes which may require coenzymes (e.g.NADH, NADPH). These elements create monomers, the building blocks for macromolecules. Some important biological macromolecules include: proteins, which are composed of amino acid monomers joined via peptide bonds, and DNA molecules, which are composed of nucleotides joined via phosphodiester bonds.
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