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Studies of Fatty Acid Oxidation IX. The Effects of
Studies of Fatty Acid Oxidation IX. The Effects of

... the Ehrlich carcinoma or Sarcoma 37 was relatively resistant to loss of adenosine triphosphate (ATP) produced by uncoupling agents, such as dinitrophenol (DNP) or the fatty acids themselves. However, the rate of incorporation of palmitate-l-C14 into phospholipides was decreased in the presence of DN ...
TCA (Krebs) Cycle
TCA (Krebs) Cycle

...  Tricarboxylic acid cycle (TCA), Krebs cycle, ...
Enzymes - Dr. Hamad Ali Yaseen
Enzymes - Dr. Hamad Ali Yaseen

CELLULAR RESPIRATION
CELLULAR RESPIRATION

... 2. During the conversion of fructose 6-phosphate to fructose 1, 6-bisphosphate. There are three major ways in which different cells handle pyruvic acid produced by glycolysis. These are lactic acid fermentation, alcoholic fermentation and aerobic respiration. Fermentation takes place under anaerobic ...
Fall 2011 Prelim 1 BioG 1440 Introduction to Comparative
Fall 2011 Prelim 1 BioG 1440 Introduction to Comparative

... Cellular respiration consists of three groups of reactions: glycolysis, the citric acid cycle, and oxidative phosphorylation. These three groups of reactions are not independent of each other but are coupled together by several different compounds. As a consequence of this coupling, 8) under anaerob ...
Supplemental Data
Supplemental Data

... Gal80p-Gal80p interaction. Gal80p-Gal80p interactions were analyzed by complex formation with a Gal80p derivative with altered gel mobility. A fusion between Gal80p and the negatively charged activation domain of Herpes simplex VP16 (Gal80pVP16) migrates faster on native gels than Gal80p by itself. ...
enzymes-regulation-text
enzymes-regulation-text

Functional lipidomics of oxidized products from polyunsaturated fatty
Functional lipidomics of oxidized products from polyunsaturated fatty

... We have been interested in hydroxy-alkenals that may be issued from the whole series of omega-3 or omega-6 PUFA, in contrast to isoprostanes and neuroprostanes that are products of ARA and DHA only. In that case, 4-hydroxy-hexenal (4-HHE) and 4-hydroxy-nonenal (4-HNE) are indices of omega-3 and ome ...
Biophysical Society On
Biophysical Society On

... side chain and backbone, this same steric hindrance is the origin of α and β secondary structures. There is no sequence dependence on the steric restrictions of the α and β space because φ,ψ restrictions arise within each residue rather than between residues. However, a sequence of residues that all ...
Canine Osteosarcoma
Canine Osteosarcoma

... Factor affecting absorption 1. Chemical form – Organic, Inorganic 2. Other dietary factor –pH, Solubility etc., ...
The α-ketoglutarate dehydrogenase complex in cancer metabolic
The α-ketoglutarate dehydrogenase complex in cancer metabolic

... Fig. 1 Regulation mechanisms of α-KGDC. α-KGDC is a complex consisting of multiple copies of three enzymes: α-ketoglutarate dehydrogenase (E1), dihydrolipoamide succinyltransferase (E2), and dihydrolipoamide dehydrogenase (E3). α-KG reacts with the TPP that binds E1, and is thereby a decarboxylated- ...
Pyruvate Kinase
Pyruvate Kinase

...  pyruvate produced in Glycolysis is oxidized to CO2 via Krebs Cycle (can also be stored as fatty acids)  NADH produced in Glycolysis & Krebs Cycle is reoxidized via the respiratory chain, with production of much additional ATP. ...
Glycogen Metabolism Gluconeogenesis
Glycogen Metabolism Gluconeogenesis

... • In the “resting” state, Gα is bound to the Gβ-Gγ dimer. Gα contains the nucleotide binding site, holding GDP in the inactive form, and is the “warhead” of the G protein. At least 20 different forms of Ga exist in mammalian cells. • Binding of the extracellular signal by the GPCR causes it to under ...
Human Physiology - Maryville University
Human Physiology - Maryville University

... when pyruvate formed by glycolysis enters mitochondria  C02 is clipped off pyruvate forming acetyl CoA (coenzyme A is a carrier for acetic acid)  C02 goes to lungs  Energy in acetyl CoA is extracted during aerobic respiration in mitochondria ...
Purine Oct 20 - LSU School of Medicine
Purine Oct 20 - LSU School of Medicine

... Hydrolysis occurs by nucleophilic attack of the 2’-hydroxyl group on the polarized phosphate to yield a 2’-3’ cyclic phosphodiester intermediate (circled) that subsequently spontaneously hydrolyzes to a mix of 2’- and 3’phosphomonoesters. ...
Lipid metabolism in the fowl under normal and abnormal
Lipid metabolism in the fowl under normal and abnormal

... high concentration in the pancreas, about ten times greater than that in mammals (Hazelwood, 1973). On the other hand, the concentration of insulin is comparatively low and reflects its relatively minor role in the control of avian metabolism (Hazelwood, I 973). No significant anti-lipolytic effects ...
Anaerobic-and-Aerobic
Anaerobic-and-Aerobic

... described below. Lactic Acid Fermentation This fermentation is carried out by the bacteria in yogurt. It is also used by your own muscle cells when you work them hard and fast. Did you ever run a race and notice that your muscles feel tired and sore afterward? This is because your muscle cells used ...
Acid Base Balance
Acid Base Balance

... pH <6.9 or >7.7: generally incompatible with life pH determines shape and thus function of many biological molecules, particularly proteins Enzymes & ion channels are examples of protein molecules sensitive to pH (modifies structural bonds, changing shape and function) ...
AP Biology “What You Need To KNOW” for Free Energy
AP Biology “What You Need To KNOW” for Free Energy

... Be able to model and explain how ATP is used to complete tasks “work” in the cell. Explain a specific chemical, mechanical, and transport mechanism using ATP as an energy coupling molecule. Explain energy coupling in detail utilizing ΔG = -7.3 kcal/mol . How much work can it do??? Compare / Contrast ...
BIOCHEMISTRY
BIOCHEMISTRY

... Biochemistry or Biological chemistry is the branch of knowledge that deals with the structure of chemical compounds that make up part of living matter, their transformations and physico-chemical processes that constitute the basis of vital activity. Biochemistry is a part of Biology; it encompasses ...
A. Primary structure: - B. Secondary structure: -
A. Primary structure: - B. Secondary structure: -

... Example: phosphorylase enzyme which contains two identical subunits that alone inactive but when joined as a dimer form the active enzyme. The forces that stabilize the aggregation in structure are hydrogen bonds & electrostatic interaction formed between residues on the surfaces of the polypeptide ...
Direct Comparison DNA and Amino Acid Sequences Based on a
Direct Comparison DNA and Amino Acid Sequences Based on a

... The algorithm we use to directly compare a DNA sequence with an amino acid sequence, has three steps : 1) translating the DNA sequence into an amino acid sequence nucleotide - by - nucleotide, 2) comparing the translated amino acid sequence with amino acid sequences in the database, allowing gaps to ...
chapter 3
chapter 3

... When you have mastered this chapter, you should be able to complete the following objectives. Introduction 1. List the key properties of proteins. 2. Explain how proteins relate one-dimensional gene structure to three-dimensional structure in the cell, and their complex interactions with each other ...
File
File

... Building blocks for DNA and RNA “Second messengers” in signal transduction cascades Energy “currency” of the cell Components of major co-enzymes ...
Acid Base Balance
Acid Base Balance

... pH <6.9 or >7.7: generally incompatible with life pH determines shape and thus function of many biological molecules, particularly proteins Enzymes & ion channels are examples of protein molecules sensitive to pH (modifies structural bonds, changing shape and function) ...
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Metabolism



Metabolism (from Greek: μεταβολή metabolē, ""change"") is the set of life-sustaining chemical transformations within the cells of living organisms. These enzyme-catalyzed reactions allow organisms to grow and reproduce, maintain their structures, and respond to their environments. The word metabolism can also refer to all chemical reactions that occur in living organisms, including digestion and the transport of substances into and between different cells, in which case the set of reactions within the cells is called intermediary metabolism or intermediate metabolism.Metabolism is usually divided into two categories: catabolism, the breaking down of organic matter by way of cellular respiration, and anabolism, the building up of components of cells such as proteins and nucleic acids. Usually, breaking down releases energy and building up consumes energy.The chemical reactions of metabolism are organized into metabolic pathways, in which one chemical is transformed through a series of steps into another chemical, by a sequence of enzymes. Enzymes are crucial to metabolism because they allow organisms to drive desirable reactions that require energy that will not occur by themselves, by coupling them to spontaneous reactions that release energy. Enzymes act as catalysts that allow the reactions to proceed more rapidly. Enzymes also allow the regulation of metabolic pathways in response to changes in the cell's environment or to signals from other cells.The metabolic system of a particular organism determines which substances it will find nutritious and which poisonous. For example, some prokaryotes use hydrogen sulfide as a nutrient, yet this gas is poisonous to animals. The speed of metabolism, the metabolic rate, influences how much food an organism will require, and also affects how it is able to obtain that food.A striking feature of metabolism is the similarity of the basic metabolic pathways and components between even vastly different species. For example, the set of carboxylic acids that are best known as the intermediates in the citric acid cycle are present in all known organisms, being found in species as diverse as the unicellular bacterium Escherichia coli and huge multicellular organisms like elephants. These striking similarities in metabolic pathways are likely due to their early appearance in evolutionary history, and their retention because of their efficacy.
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