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Full Text PDF - Mary Ann Liebert, Inc. publishers
Full Text PDF - Mary Ann Liebert, Inc. publishers

... mpaired bioenergetics and mitochondria metabolism, together with oxidative stress, are commonalities underlying age-related neurodegenerative diseases, such as Parkinson’s (PD), Huntington’s (HD) and Alzheimer’s (AD) disease, Friedreich’s ataxia, or amyotrophic lateral sclerosis (ALS), to cite a few ...
2007 Workshop handout
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Chapter 12 Lecture Notes: Metabolism – Enzyme and Gene
Chapter 12 Lecture Notes: Metabolism – Enzyme and Gene

... A. Why regulate? 1. Bacteria are extremely efficient organisms. It is wasteful to have all 1000 – 2000 metabolic pathways on at the same time. 2. During exponential growth all cellular components are synthesized at constant rates relative to one another (balanced growth). 3. Thus, the cell integrate ...
06a Organic Acids 2
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... Isocitrate supplies precursors (succinate and glyoxylate) for two OAA,  thus allowing the synthesis of 2 citrate,  one to be excreted, the second to continue the glyox. cycle. ...
Chapt 8 Energetics notes - Kasson
Chapt 8 Energetics notes - Kasson

... Purpose of the e- transport chain? • A H+ (proton) concentration gradient is produced by the movement of electrons along the electron transport chain. • Several chain molecules can use the energy from the flow of electrons down the chain to pump H+ from the matrix to the ...
prospect benecord
prospect benecord

... wheat, etc. Policosanol has an inhibitor effect on the enzymes responsible for the endogenous synthesis of cholesterol in the liver. Clinical studies have proven a synergic effect between policosanol and the Omega 3 fatty acids found in fish oil, the beneficial effects on the cholesterol level and s ...
Protein Structure
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...  Proteasomes-Cytoplasmic complexes-Older and abnormal protein  Proteasomes are large protein complexes inside all eukaryotes and in some bacteria.  In eukaryotes, they are located in the nucleus and the cytoplasm.  The main function of the proteasome is to degrade unneeded or damaged proteins by ...
Multiple Choice Questions
Multiple Choice Questions

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as a PDF

... Fructose, glucose and sucrose, as the major soluble sugars and citric and malic acids, as the major organic acids, were identified and determined in kale (Brassica oleraceae L. var. acephala DC., black cabbage) leaves. Fructose was the predominant sugar (2011 mg 100 g 1 dry wt) identified, followed by ...
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26. oxidation of amino acids

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Metabolic Acidosis

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- Cal State LA - Instructional Web Server
- Cal State LA - Instructional Web Server

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ภาพนิ่ง 1

... enzyme will utilize (an example will be discussed). • It is also useful for comparing similar enzymes from different tissues or different organisms. • Also, it is the Km of the rate-limiting enzyme in many of the biochemical metabolic pathways that determines the amount of product and overall regula ...
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2O2 - + 2H+ ------> H2O2 + O2 M3+ + O2 - ------> M2+ + O2 i
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... 1) The oxidation state on any atom in its elemental form is zero (H2, O2, Na(s)) 2) The sum of the oxidation states of all atoms in a neutral compound is zero (CH4, NH3) 3) The sum of the oxidation states of all atoms in an ion is equal to the charge on the ion (NO3-, SO42-) 4) The oxidation state o ...
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... decryption techniques were used from ancient times. Nowadays biology techniques are proposed for encryption and decryption. As known Amino-acids are molecules containing an amine group, a carboxylic acid group and a side-chain that varies between different amino acids. The key elements of an amino a ...
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Chapter - I 1 1.1. Introduction to amino acids

... threonine in a peptide is a determining factor as to whether or not the hydroxyl group will be glycosylated. This type of reaction usually occurs as a peptide is being transferred from the endoplasmic reticulum to the Golgi apparatus [7]. Histidine, lysine and arginine are classified according to th ...
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Case Study Powerpoints - Westford Academy Ap Bio
Case Study Powerpoints - Westford Academy Ap Bio

...  When substrates are in active site, enzyme undergoes conformational change  Conformational change brings chemical groups of active site into position to enhance their ability to catalyze reaction  When reaction complete, resulting molecules released and enzyme takes on previous conformation for ...
Ch06 and 7_lecture
Ch06 and 7_lecture

... 2. Energy from food is then stored as a phosphate bond in ATP. 3. Energy is then released when the phosphate bond is broken, and can be used to fuel our everyday activities. ...
full text - pdf 348 kB
full text - pdf 348 kB

... short strokes (dashes, hyphens). At times, special symbols have been used (> or —*) to show the direction of what is in all cases an unsymmetrical link (peptide or glycoside). For consistency and ease of typing as well as economy in printing, the hyphen, representing the peptide bond, should be the ...
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Metabolism



Metabolism (from Greek: μεταβολή metabolē, ""change"") is the set of life-sustaining chemical transformations within the cells of living organisms. These enzyme-catalyzed reactions allow organisms to grow and reproduce, maintain their structures, and respond to their environments. The word metabolism can also refer to all chemical reactions that occur in living organisms, including digestion and the transport of substances into and between different cells, in which case the set of reactions within the cells is called intermediary metabolism or intermediate metabolism.Metabolism is usually divided into two categories: catabolism, the breaking down of organic matter by way of cellular respiration, and anabolism, the building up of components of cells such as proteins and nucleic acids. Usually, breaking down releases energy and building up consumes energy.The chemical reactions of metabolism are organized into metabolic pathways, in which one chemical is transformed through a series of steps into another chemical, by a sequence of enzymes. Enzymes are crucial to metabolism because they allow organisms to drive desirable reactions that require energy that will not occur by themselves, by coupling them to spontaneous reactions that release energy. Enzymes act as catalysts that allow the reactions to proceed more rapidly. Enzymes also allow the regulation of metabolic pathways in response to changes in the cell's environment or to signals from other cells.The metabolic system of a particular organism determines which substances it will find nutritious and which poisonous. For example, some prokaryotes use hydrogen sulfide as a nutrient, yet this gas is poisonous to animals. The speed of metabolism, the metabolic rate, influences how much food an organism will require, and also affects how it is able to obtain that food.A striking feature of metabolism is the similarity of the basic metabolic pathways and components between even vastly different species. For example, the set of carboxylic acids that are best known as the intermediates in the citric acid cycle are present in all known organisms, being found in species as diverse as the unicellular bacterium Escherichia coli and huge multicellular organisms like elephants. These striking similarities in metabolic pathways are likely due to their early appearance in evolutionary history, and their retention because of their efficacy.
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