CHAPTER 6
... The effect of the 5-fluoro substitution on the mechanism of action of thymidylate synthase. An enzyme thiol group (from a Cys side chain) ordinarily attacks the 6position of dUMP so that C-5 can react as a carbanion with N5,N10-methylene-THF. Normally, free enzyme is regenerated following release of ...
... The effect of the 5-fluoro substitution on the mechanism of action of thymidylate synthase. An enzyme thiol group (from a Cys side chain) ordinarily attacks the 6position of dUMP so that C-5 can react as a carbanion with N5,N10-methylene-THF. Normally, free enzyme is regenerated following release of ...
A macrokinetic and regulator model for myeloma cell culture based
... However, it is found that the real glucose uptake rate is much lower than rglc,M at the beginning of cultivation, even though the glucose concentration is the highest. Such discrepancy exists for most Monod type models because the Monod model does not take the induction of the enzyme pool involved i ...
... However, it is found that the real glucose uptake rate is much lower than rglc,M at the beginning of cultivation, even though the glucose concentration is the highest. Such discrepancy exists for most Monod type models because the Monod model does not take the induction of the enzyme pool involved i ...
Triacylglycerol and Phospholipid Biosynthesis
... Triacylglycerol and Phospholipid Biosynthesis March 28, 2003 Bryant Miles I. Regulation of Fatty acid Metabolism It is energetically wasteful to have fatty acid synthesis and β-oxidation occurring at the same time. Hence these 2 metabolic pathways are reciprocally regulated. This coordinated regulat ...
... Triacylglycerol and Phospholipid Biosynthesis March 28, 2003 Bryant Miles I. Regulation of Fatty acid Metabolism It is energetically wasteful to have fatty acid synthesis and β-oxidation occurring at the same time. Hence these 2 metabolic pathways are reciprocally regulated. This coordinated regulat ...
The synthesis of peptides and proteins containing non
... The activated acyl group is transferred from the A domain to the thiol of a pantothene moiety covalently bound to the T domain, forming a thioester as the active acylating agent. This formally corresponds to the activation of acyl groups as thioesters of Coenzyme A in polyketide synthesis, and utili ...
... The activated acyl group is transferred from the A domain to the thiol of a pantothene moiety covalently bound to the T domain, forming a thioester as the active acylating agent. This formally corresponds to the activation of acyl groups as thioesters of Coenzyme A in polyketide synthesis, and utili ...
Extracting System of Accurate ORFs
... extraction of amino acid sequence from a cDNA sequence. In the frame each position of initiation and termination codon is displayed and a segment that starts at an initiation codon and terminates at a termination codon is identified; the obtained segments are identified as possible open reading fram ...
... extraction of amino acid sequence from a cDNA sequence. In the frame each position of initiation and termination codon is displayed and a segment that starts at an initiation codon and terminates at a termination codon is identified; the obtained segments are identified as possible open reading fram ...
enriched protein products of marine origin like the new components
... taken as a basis for the development of the shrimp biomass [3]. According to the Institute of Nutrition of the Russian Academy of Medical Sciences, soy protein is easily digestible, high-value, reasonably balanced in terms of amino acid composition, comparable in biological value with the protein of ...
... taken as a basis for the development of the shrimp biomass [3]. According to the Institute of Nutrition of the Russian Academy of Medical Sciences, soy protein is easily digestible, high-value, reasonably balanced in terms of amino acid composition, comparable in biological value with the protein of ...
Thermogen Fat Oxidiser - Body Ripped Sports Nutrition
... loss by supporting thermogenesis and fat oxidation, and by sustaining energy levels. How does Thermogen Fat Oxidiser achieve all this? Thermogen contains the herbal extract Citrus Aurantium, which - according to research - may help increase your metabolic rate and provide a thermogenic effect. Therm ...
... loss by supporting thermogenesis and fat oxidation, and by sustaining energy levels. How does Thermogen Fat Oxidiser achieve all this? Thermogen contains the herbal extract Citrus Aurantium, which - according to research - may help increase your metabolic rate and provide a thermogenic effect. Therm ...
Some stereochemical terms
... digested, it must be broken down by an enzyme called lactase, and individuals lacking this enzyme have lactose intolerance. Presumably this problem led to the development of fermentation processes to produce yogurt in which the lactose is hydrolyzed by micorbial action. Sucrose is a major sugar prod ...
... digested, it must be broken down by an enzyme called lactase, and individuals lacking this enzyme have lactose intolerance. Presumably this problem led to the development of fermentation processes to produce yogurt in which the lactose is hydrolyzed by micorbial action. Sucrose is a major sugar prod ...
Development of Technology for Quality Evaluation of Human
... measured metabolite areas also confirmed no substantial difference in results between each of the extraction conditions for organic acids, amino acids and sugars (Fig. 3). The highest signal intensities for nucleotides and bases were observed when using the MeOH-H2O method (Fig. 3). In light of the ...
... measured metabolite areas also confirmed no substantial difference in results between each of the extraction conditions for organic acids, amino acids and sugars (Fig. 3). The highest signal intensities for nucleotides and bases were observed when using the MeOH-H2O method (Fig. 3). In light of the ...
C12P
... o Non-metals: H, B, C, Si, N, P, O, S, Se, Te, noble gases, halogens o Metals: elements other than non-metals o Transition elements: elements with atomic numbers 21 to 30 inclusive, 39 to 48 inclusive, 57 to 80 inclusive, 89 upwards Section C covers : o pure chemistry, which covers inorganic compoun ...
... o Non-metals: H, B, C, Si, N, P, O, S, Se, Te, noble gases, halogens o Metals: elements other than non-metals o Transition elements: elements with atomic numbers 21 to 30 inclusive, 39 to 48 inclusive, 57 to 80 inclusive, 89 upwards Section C covers : o pure chemistry, which covers inorganic compoun ...
Leader The molecular basis of disorders of red cell enzymes
... The mature red cell has no nucleus or organelles and therefore cannot synthesise protein or lipids. It is totally dependent on glycolysis to convert glucose into an energy source. Glucose is phosphorylated by hexokinase to glucose-6-phosphate. This is the substrate for anaerobic glycolysis which pro ...
... The mature red cell has no nucleus or organelles and therefore cannot synthesise protein or lipids. It is totally dependent on glycolysis to convert glucose into an energy source. Glucose is phosphorylated by hexokinase to glucose-6-phosphate. This is the substrate for anaerobic glycolysis which pro ...
DFT Chemical Reactivity Analysis of Biological Molecules in the
... enzymes; this by forming complexes with the sulfur of the thiol group of cysteine [16,17]. It is also been reported that silver can be involved in catalytic oxidation reactions resulting from the formation of disulfide bonds (R-S-S-R). It catalyzes the reaction between oxygen molecules in the thiol ...
... enzymes; this by forming complexes with the sulfur of the thiol group of cysteine [16,17]. It is also been reported that silver can be involved in catalytic oxidation reactions resulting from the formation of disulfide bonds (R-S-S-R). It catalyzes the reaction between oxygen molecules in the thiol ...
Prezentace aplikace PowerPoint
... Effects of food composition on obesity onset Hypothesis: High concentration of fat in food intake of calories development of obesity Results of research: – satiating efficiency of fat is smaller than carbohydrates and proteins passive overeating – high energy concentration in fat unit of fo ...
... Effects of food composition on obesity onset Hypothesis: High concentration of fat in food intake of calories development of obesity Results of research: – satiating efficiency of fat is smaller than carbohydrates and proteins passive overeating – high energy concentration in fat unit of fo ...
Biol115_2014_Lecture 8_Protein Structure
... Proteins have many structures, resulting in a wide range of functions • Proteins account for more than 50 % of the dry mass of most cells. • Protein functions include: • Metabolism ...
... Proteins have many structures, resulting in a wide range of functions • Proteins account for more than 50 % of the dry mass of most cells. • Protein functions include: • Metabolism ...
enzyme structure
... common being the ribosome; these are referred to as either RNA-enzymes or ribozymes. The activities of enzymes are determined by their three-dimensional structure. However, although structure does determine function, predicting a novel enzyme's activity just from its structure is a very difficult pr ...
... common being the ribosome; these are referred to as either RNA-enzymes or ribozymes. The activities of enzymes are determined by their three-dimensional structure. However, although structure does determine function, predicting a novel enzyme's activity just from its structure is a very difficult pr ...
structure-helix-text
... Gly: R group is a single H atom and destabilizes the structure since rotation around the Cα is unconstrained ...
... Gly: R group is a single H atom and destabilizes the structure since rotation around the Cα is unconstrained ...
Protein expression during exponential growth in 0.7 M NaCl medium
... polyacrylamide gel electrophoresis (2D-PAGE) generated images of isotopically labelled protein extracts have been performed in a quantitative investigation of the cellular adaptation process to NaCl containing medium [8]. It was reported that drastic expression changes occurred during the osmotic ad ...
... polyacrylamide gel electrophoresis (2D-PAGE) generated images of isotopically labelled protein extracts have been performed in a quantitative investigation of the cellular adaptation process to NaCl containing medium [8]. It was reported that drastic expression changes occurred during the osmotic ad ...
Bio-Organic Chemistry will Page | 1
... biological fluids. There will be more applications of UV-Vis spectroscopy in CHEM 122 and 220. Infra-Red (IR) Spectroscopy IR energy is long wavelength (hence low energy) light below visible red in the spectrum. It is the same as what you feel in your toaster and what you [don't] see in your toaster ...
... biological fluids. There will be more applications of UV-Vis spectroscopy in CHEM 122 and 220. Infra-Red (IR) Spectroscopy IR energy is long wavelength (hence low energy) light below visible red in the spectrum. It is the same as what you feel in your toaster and what you [don't] see in your toaster ...
Practical Methods for Biocatalysis and Biotransformations 2 Brochure
... are given and relevant references to the primary literature are cited. This second volume which can be used on its own or in combination with the first volume – concentrates on new techniques and new enzyme families that have been reported since the first volume. Up–to–date protocols and industry ex ...
... are given and relevant references to the primary literature are cited. This second volume which can be used on its own or in combination with the first volume – concentrates on new techniques and new enzyme families that have been reported since the first volume. Up–to–date protocols and industry ex ...
AP Biology
... 12. Draw two amino acids – note the amino group, the carboxyl group and the alpha carbon, circle the water molecule to be removed and then note the peptide bond formed when the two are joined. ...
... 12. Draw two amino acids – note the amino group, the carboxyl group and the alpha carbon, circle the water molecule to be removed and then note the peptide bond formed when the two are joined. ...
Supplemental Methods
... Sample injection volumes varied from 2-8 µL. Peptides were eluted at a flow rate of 40 µL/min, with linear gradients of 0-65% acetonitrile and 0.1% formic acid, during 10 min, followed by 5 min at 95% of acetonitrile and 0.1% formic acid. Peptides were ionized using a 4000V needle potential and 300º ...
... Sample injection volumes varied from 2-8 µL. Peptides were eluted at a flow rate of 40 µL/min, with linear gradients of 0-65% acetonitrile and 0.1% formic acid, during 10 min, followed by 5 min at 95% of acetonitrile and 0.1% formic acid. Peptides were ionized using a 4000V needle potential and 300º ...
Higher Human Biology unit 1 section 5 ENZYMES
... • A 1 molar solution is produced when 138g are dissolved in 1 litre of water. • A 0.1 molar solution is produced when 13.8g are dissolved in 100ml of water • A 0.01 molar solution is produced when 1.38g are dissolved in 100ml of water Work out what weights of sodium phosphate need to be added to 100 ...
... • A 1 molar solution is produced when 138g are dissolved in 1 litre of water. • A 0.1 molar solution is produced when 13.8g are dissolved in 100ml of water • A 0.01 molar solution is produced when 1.38g are dissolved in 100ml of water Work out what weights of sodium phosphate need to be added to 100 ...
Metabolism
Metabolism (from Greek: μεταβολή metabolē, ""change"") is the set of life-sustaining chemical transformations within the cells of living organisms. These enzyme-catalyzed reactions allow organisms to grow and reproduce, maintain their structures, and respond to their environments. The word metabolism can also refer to all chemical reactions that occur in living organisms, including digestion and the transport of substances into and between different cells, in which case the set of reactions within the cells is called intermediary metabolism or intermediate metabolism.Metabolism is usually divided into two categories: catabolism, the breaking down of organic matter by way of cellular respiration, and anabolism, the building up of components of cells such as proteins and nucleic acids. Usually, breaking down releases energy and building up consumes energy.The chemical reactions of metabolism are organized into metabolic pathways, in which one chemical is transformed through a series of steps into another chemical, by a sequence of enzymes. Enzymes are crucial to metabolism because they allow organisms to drive desirable reactions that require energy that will not occur by themselves, by coupling them to spontaneous reactions that release energy. Enzymes act as catalysts that allow the reactions to proceed more rapidly. Enzymes also allow the regulation of metabolic pathways in response to changes in the cell's environment or to signals from other cells.The metabolic system of a particular organism determines which substances it will find nutritious and which poisonous. For example, some prokaryotes use hydrogen sulfide as a nutrient, yet this gas is poisonous to animals. The speed of metabolism, the metabolic rate, influences how much food an organism will require, and also affects how it is able to obtain that food.A striking feature of metabolism is the similarity of the basic metabolic pathways and components between even vastly different species. For example, the set of carboxylic acids that are best known as the intermediates in the citric acid cycle are present in all known organisms, being found in species as diverse as the unicellular bacterium Escherichia coli and huge multicellular organisms like elephants. These striking similarities in metabolic pathways are likely due to their early appearance in evolutionary history, and their retention because of their efficacy.