Gene Set Enrichment Analysis
... • Ranks all genes on array based on their differential expression • Identifies gene sets whose member genes are clustered either towards top or bottom of the ranked list (i.e. up- or down regulated) • Enrichment score calculated for each category • Permutation test to identify significantly enriched ...
... • Ranks all genes on array based on their differential expression • Identifies gene sets whose member genes are clustered either towards top or bottom of the ranked list (i.e. up- or down regulated) • Enrichment score calculated for each category • Permutation test to identify significantly enriched ...
Slides
... • Genetic drift, gene flow and mutations & natural selection all lead to changes in variation within a population • Natural selection leads to adaptive evolution ...
... • Genetic drift, gene flow and mutations & natural selection all lead to changes in variation within a population • Natural selection leads to adaptive evolution ...
VIDEO SUMMARIES: GENETIC VARIATION
... • Natural%selec4on%is%the%process%whereby%organisms%that%are%be:er%suited%to% the%environment%tend%to%survive%and%produce%offspring% • Purpose:%to%help%the%survival%of%the%popula4on% • Chatham%Island%(NZ)%Black%Robin% • All%from%5%one%female% • Now%250+% • No%inbreeding%effects% • Due%to%small% ...
... • Natural%selec4on%is%the%process%whereby%organisms%that%are%be:er%suited%to% the%environment%tend%to%survive%and%produce%offspring% • Purpose:%to%help%the%survival%of%the%popula4on% • Chatham%Island%(NZ)%Black%Robin% • All%from%5%one%female% • Now%250+% • No%inbreeding%effects% • Due%to%small% ...
Evolution II Task Review Answers
... 1. Adaptive radiation: a type of divergent evolution that occurs very quickly in a given area, the ancestral finches came from South America and spread to the different islands and adapted to their new environments 2. Double bubble gradualism and punctuated equilibrium Similarity: used to describe t ...
... 1. Adaptive radiation: a type of divergent evolution that occurs very quickly in a given area, the ancestral finches came from South America and spread to the different islands and adapted to their new environments 2. Double bubble gradualism and punctuated equilibrium Similarity: used to describe t ...
Lecture 1-Genetics 1
... Fragmentation of the elastic fibers in the tunica media of the aorta predisposes to aneurysmal dilation and aortic dissection. Dilation of the aortic valve ring, giving rise to aortic incompetence. The cardiac valves, especially the mitral valve, may be excessively distensible and regurgitant (flopp ...
... Fragmentation of the elastic fibers in the tunica media of the aorta predisposes to aneurysmal dilation and aortic dissection. Dilation of the aortic valve ring, giving rise to aortic incompetence. The cardiac valves, especially the mitral valve, may be excessively distensible and regurgitant (flopp ...
Essential Question: How is the combination of genes
... S7L3a. Explain the role of genes and chromosomes in the process of inheriting a specific trait. S7L3c. Recognize the selective breeding can produce plants and animals with desired traits. ...
... S7L3a. Explain the role of genes and chromosomes in the process of inheriting a specific trait. S7L3c. Recognize the selective breeding can produce plants and animals with desired traits. ...
Document
... Interaction of two dominant alleles (R & P), produces a third phenotype (walnut), all F1 are walnut-combed (Rr/Pp). ...
... Interaction of two dominant alleles (R & P), produces a third phenotype (walnut), all F1 are walnut-combed (Rr/Pp). ...
PopulationGenetics_Inbreeding_RiskAssessment
... Once a gene frequency achieves 100%, the gene is considered fixed o Founder Effects If there is a higher proportion of an allele in a founding population than the general population, that allele will maintain that higher frequency, barring reproduction outside that segregated population o Bottle ...
... Once a gene frequency achieves 100%, the gene is considered fixed o Founder Effects If there is a higher proportion of an allele in a founding population than the general population, that allele will maintain that higher frequency, barring reproduction outside that segregated population o Bottle ...
When Parents are Related
... If parents are first cousins, the chance is a little higher at 5% to 6%. This is due to the increased chance that they will both carry the same autosomal recessive mutation, passed down through the family. In general, when parents are consanguineous, they do not have an increased chance of having a ...
... If parents are first cousins, the chance is a little higher at 5% to 6%. This is due to the increased chance that they will both carry the same autosomal recessive mutation, passed down through the family. In general, when parents are consanguineous, they do not have an increased chance of having a ...
Genetics
... Epistasis and Lab Pups If I cross a Brown Lab (bbEe) with a Black Lab (BbEe), can I expect any yellow ...
... Epistasis and Lab Pups If I cross a Brown Lab (bbEe) with a Black Lab (BbEe), can I expect any yellow ...
Chapter 4 Heredity and Evolution
... governed by alleles at more than one genetic locus. Continuous traits show gradations. Skin color is a common example of a polygenic trait it is governed by 6 loci and at least 12 alleles. ...
... governed by alleles at more than one genetic locus. Continuous traits show gradations. Skin color is a common example of a polygenic trait it is governed by 6 loci and at least 12 alleles. ...
Biology
... c. define and properly use all vocabulary d. properly apply all terms and concepts in describing/explaining real world examples e. make and interpret scientific graphs and diagrams f. teach someone else the concepts discussed g. practice proper laboratory safety This will be accomplished by each stu ...
... c. define and properly use all vocabulary d. properly apply all terms and concepts in describing/explaining real world examples e. make and interpret scientific graphs and diagrams f. teach someone else the concepts discussed g. practice proper laboratory safety This will be accomplished by each stu ...
Document
... • Probability that someone who inherits an allele will have the phenotype associated with it ...
... • Probability that someone who inherits an allele will have the phenotype associated with it ...
The American Journal of Human Genetics
... H3-K36me3, and this in turn recruits the splice regulator PTB to FGFR2. The same histone modifications and binding proteins influence alternative splicing at other genes but are not the universal regulators of splicing. However, it seems plausible that the same type of system could be used for regulat ...
... H3-K36me3, and this in turn recruits the splice regulator PTB to FGFR2. The same histone modifications and binding proteins influence alternative splicing at other genes but are not the universal regulators of splicing. However, it seems plausible that the same type of system could be used for regulat ...
Evolution as Genetic Change
... For polygenic traits, natural selection can have three effects on phenotypes. Each of these can be represented by the type of curve that would result from a graph. 1. Directional selection- individuals at one end have higher fitness than those in the middle or at the opposite end. 2. Stabilizing se ...
... For polygenic traits, natural selection can have three effects on phenotypes. Each of these can be represented by the type of curve that would result from a graph. 1. Directional selection- individuals at one end have higher fitness than those in the middle or at the opposite end. 2. Stabilizing se ...
Epistasis
Epistasis is a phenomenon that consists of the effect of one gene being dependent on the presence of one or more 'modifier genes' (genetic background). Similarly, epistatic mutations have different effects in combination than individually. It was originally a concept from genetics but is now used in biochemistry, population genetics, computational biology and evolutionary biology. It arises due to interactions, either between genes, or within them leading to non-additive effects. Epistasis has a large influence on the shape of evolutionary landscapes which leads to profound consequences for evolution and evolvability of traits.