Global Transcriptional Profiling Reveals Distinct Functions of Thymic
... thymic stromal subsets from mice at 1, 3, and 6 months of age, enabling the community to query stromal subset-specific gene expression before and during early thymic involution. Griffith et al. (2009, 2012) previously reported transcriptional profiles of nonsorted thymic stroma from the cortex, medu ...
... thymic stromal subsets from mice at 1, 3, and 6 months of age, enabling the community to query stromal subset-specific gene expression before and during early thymic involution. Griffith et al. (2009, 2012) previously reported transcriptional profiles of nonsorted thymic stroma from the cortex, medu ...
Category 2000
... coactivator 1 (PPARGC1A) is a versatile coactivator with many functions, but is primarily involved in fat and energy metabolism. Therefore, it is a very interesting candidate gene for meat quality, which is one of the most important criteria in pig selection today. PPARGC1A however, does not have th ...
... coactivator 1 (PPARGC1A) is a versatile coactivator with many functions, but is primarily involved in fat and energy metabolism. Therefore, it is a very interesting candidate gene for meat quality, which is one of the most important criteria in pig selection today. PPARGC1A however, does not have th ...
Towards an accurate identification of mosaic genes and
... and bacteria (4). Two models of HGT have been considered in the literature (5). First, and the most popular of them, is the traditional model of complete HGT. It assumes that the transferred gene either supplants the orthologous gene of the recipient genome or, when the transferred gene is absent in ...
... and bacteria (4). Two models of HGT have been considered in the literature (5). First, and the most popular of them, is the traditional model of complete HGT. It assumes that the transferred gene either supplants the orthologous gene of the recipient genome or, when the transferred gene is absent in ...
Multiple Roles of the Y Chromosome in the Biology of
... It is generally accepted that the sex chromosomes of most animals arose from a couple of homologous autosomes after the acquisition of a dominant sex determination gene[17,18] and that the Y chromosome is the result of the degeneration of one of them[19,20,21]. Its degeneration would be a consequenc ...
... It is generally accepted that the sex chromosomes of most animals arose from a couple of homologous autosomes after the acquisition of a dominant sex determination gene[17,18] and that the Y chromosome is the result of the degeneration of one of them[19,20,21]. Its degeneration would be a consequenc ...
TDR Targets: a chemogenomics resource for neglected diseases
... The TDR Targets Database (http://tdrtargets.org) has been designed and developed as an online resource to facilitate the rapid identification and prioritization of molecular targets for drug development, focusing on pathogens responsible for neglected human diseases. The database integrates pathogen ...
... The TDR Targets Database (http://tdrtargets.org) has been designed and developed as an online resource to facilitate the rapid identification and prioritization of molecular targets for drug development, focusing on pathogens responsible for neglected human diseases. The database integrates pathogen ...
Towards an accurate identification of mosaic genes and partial
... and bacteria (4). Two models of HGT have been considered in the literature (5). First, and the most popular of them, is the traditional model of complete HGT. It assumes that the transferred gene either supplants the orthologous gene of the recipient genome or, when the transferred gene is absent in ...
... and bacteria (4). Two models of HGT have been considered in the literature (5). First, and the most popular of them, is the traditional model of complete HGT. It assumes that the transferred gene either supplants the orthologous gene of the recipient genome or, when the transferred gene is absent in ...
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... organizer gene. However, expression analysis of Hr_lhx1 in the ascidian showed that whereas late expression of Hr_lhx1 was detected in the brain from the tailbud stage onward, early expression of Hr_lhx1 was not detectable at the blastula to gastrula stages by WISH (Fig. 1H,I; data not shown). Becau ...
... organizer gene. However, expression analysis of Hr_lhx1 in the ascidian showed that whereas late expression of Hr_lhx1 was detected in the brain from the tailbud stage onward, early expression of Hr_lhx1 was not detectable at the blastula to gastrula stages by WISH (Fig. 1H,I; data not shown). Becau ...
A Bayesian Network Classification Methodology for Gene
... nondescendants conditionally independent. It follows from these conditional independence assertions and the laws of probability that once a conditional distribution is associated with each node, specifying the probability that the node assumes a given value conditioned on the values assumed by the n ...
... nondescendants conditionally independent. It follows from these conditional independence assertions and the laws of probability that once a conditional distribution is associated with each node, specifying the probability that the node assumes a given value conditioned on the values assumed by the n ...
BROWSING GENES AND GENOMES WITH ENSEMBL
... text box (or alternatively leave the ‘Search’ drop-down list like it is and type ’human 13:32448000-33198000’ in the ‘for’ text box). 8 Click [Go]. This genomic region is located on cytogenetic band q13.1. It is made up of seven contigs, indicated by the alternating light and dark blue coloured bar ...
... text box (or alternatively leave the ‘Search’ drop-down list like it is and type ’human 13:32448000-33198000’ in the ‘for’ text box). 8 Click [Go]. This genomic region is located on cytogenetic band q13.1. It is made up of seven contigs, indicated by the alternating light and dark blue coloured bar ...
Conservation and diversification of gene function during mouthpart
... et al. 1997), whereas dac expression is required for the formation of medial leg regions (Lecuit and Cohen 1997). Lastly, Dll expression is critical for the establishment of the identity of the most distal leg regions such as the tarsal segments and claw (Campbell and Tomlinson 1998). Despite the hi ...
... et al. 1997), whereas dac expression is required for the formation of medial leg regions (Lecuit and Cohen 1997). Lastly, Dll expression is critical for the establishment of the identity of the most distal leg regions such as the tarsal segments and claw (Campbell and Tomlinson 1998). Despite the hi ...
Nutrigenomics in the Patient Care Process: Figuring Out the Puzzle
... sequence to another (switching nucleotide) • We all have SNPs • A person’s genome (and their SNPs) do not change ...
... sequence to another (switching nucleotide) • We all have SNPs • A person’s genome (and their SNPs) do not change ...
Intellectual property rights and innovation: Evidence from
... as of 2009, from genes initially sequenced by the public effort. Any observed differences in this cross-section specification could be due to an IP effect, or to non-random selection of genes into Celera’s IP. Historical accounts suggest such selection was very important in the early years of sequen ...
... as of 2009, from genes initially sequenced by the public effort. Any observed differences in this cross-section specification could be due to an IP effect, or to non-random selection of genes into Celera’s IP. Historical accounts suggest such selection was very important in the early years of sequen ...
The Ehlers-Danlos syndrome: on beyond collagens
... fibroblasts from this individual. The absence of TNX protein suggested recessive inheritance, a concept bolstered by the fact that the index patient’s clinically normal parents and two siblings each share an extended TNX/CYP21 haplotype with the proband. Since publication of our initial report, we h ...
... fibroblasts from this individual. The absence of TNX protein suggested recessive inheritance, a concept bolstered by the fact that the index patient’s clinically normal parents and two siblings each share an extended TNX/CYP21 haplotype with the proband. Since publication of our initial report, we h ...
Ribosomal proteins promote leaf adaxial identity
... protein in the large subunit of the ribosome. We then analyzed the ae6 mapping region and found another ribosomal protein coding gene (At3g25520), RPL5A (Fig. 1B). Although sequencing of the RPL5A-coding region did not show any change in the nucleotide sequence, the expression level of the RPL5A gen ...
... protein in the large subunit of the ribosome. We then analyzed the ae6 mapping region and found another ribosomal protein coding gene (At3g25520), RPL5A (Fig. 1B). Although sequencing of the RPL5A-coding region did not show any change in the nucleotide sequence, the expression level of the RPL5A gen ...
Linking Cognitive Neuroscience and Molecular Genetics: New Perspectives from Williams... Ursula Bellugi and Marie St. George (Eds.)
... & Williams syndrome (WMS) is a most compelling model of human cognition, of human genome organization, and of evolution. Due to a deletion in chromosome band 7q11.23, subjects have cardiovascular, connective tissue, and neurodevelopmental deficits. Given the striking peaks and valleys in neurocognit ...
... & Williams syndrome (WMS) is a most compelling model of human cognition, of human genome organization, and of evolution. Due to a deletion in chromosome band 7q11.23, subjects have cardiovascular, connective tissue, and neurodevelopmental deficits. Given the striking peaks and valleys in neurocognit ...
A/a · B/b
... homozygotes, the heterozygous phenotype results from incomplete dominance or codominance. Because two of the three phenotypes contain black, either fully or in an occasional feather, you might classify erminette as an instance of incomplete dominance because it is intermediate between fully black an ...
... homozygotes, the heterozygous phenotype results from incomplete dominance or codominance. Because two of the three phenotypes contain black, either fully or in an occasional feather, you might classify erminette as an instance of incomplete dominance because it is intermediate between fully black an ...
Cotranscriptional coupling of splicing factor recruitment and
... results. Schematics of FOS and HSPA1B are shown, with black lines indicating gene regions amplified by primer sets, identified by the nucleotide at the center of the amplified region. FOS transcription was induced with calcium ionophore (gray); control cells were treated with ...
... results. Schematics of FOS and HSPA1B are shown, with black lines indicating gene regions amplified by primer sets, identified by the nucleotide at the center of the amplified region. FOS transcription was induced with calcium ionophore (gray); control cells were treated with ...
Further genetic evidence suggesting a role for the
... have a minor influence on the BMD phenotype. Updated LD data presented by the Perlegen Genome Browser Version 2 [28] reveals that the polymorphisms within RHOA that we have identified as associated with BMD are part of 2 large LD blocks that span approximately 370 kb on chromosome 3 (Fig. 2). Although ...
... have a minor influence on the BMD phenotype. Updated LD data presented by the Perlegen Genome Browser Version 2 [28] reveals that the polymorphisms within RHOA that we have identified as associated with BMD are part of 2 large LD blocks that span approximately 370 kb on chromosome 3 (Fig. 2). Although ...
Engineering of steroid biotransformation in rhodococcus van
... 2). Electrotransformation of R. erythropolis with such non-replicative plasmids, however, induced random plasmid integration events, resulting in antibiotic resistant transformants that did not have the expected gene disruption mutation. The rate of occurrence of this so-called illegitimate integrat ...
... 2). Electrotransformation of R. erythropolis with such non-replicative plasmids, however, induced random plasmid integration events, resulting in antibiotic resistant transformants that did not have the expected gene disruption mutation. The rate of occurrence of this so-called illegitimate integrat ...
CHAPTER 3 ORGANIC CHEMISTRY
... Homologous chromosomes can carry different alleles. When the homologous chromosomes separate during meiosis, the alleles are delivered to different sex cells. ...
... Homologous chromosomes can carry different alleles. When the homologous chromosomes separate during meiosis, the alleles are delivered to different sex cells. ...
special - Microbiology
... This tight clustering was first demonstrated by cloning a 35 kb fragment of S. coelicolor DNA in Streptomjcesparvd~x that conferred production of the blue-pigmented polyketide antibiotic actinorhodin on its new host, which is not known to make any structurally related compounds (Malpartida & Hopwood ...
... This tight clustering was first demonstrated by cloning a 35 kb fragment of S. coelicolor DNA in Streptomjcesparvd~x that conferred production of the blue-pigmented polyketide antibiotic actinorhodin on its new host, which is not known to make any structurally related compounds (Malpartida & Hopwood ...
Application No. DIR 108 SUMMARY INFORMATION
... genes obtained from the soil bacterium Bacillus amyloliquefaciens. Barnase encodes a ribonuclease enzyme called barnase, and barstar encodes a specific inhibitor of the barnase enzyme. Barnase is produced specifically in the male parts of GM flowers and prevents pollen production, resulting in male- ...
... genes obtained from the soil bacterium Bacillus amyloliquefaciens. Barnase encodes a ribonuclease enzyme called barnase, and barstar encodes a specific inhibitor of the barnase enzyme. Barnase is produced specifically in the male parts of GM flowers and prevents pollen production, resulting in male- ...