post-transcription
... 1. Small dsRNA fragments can silence the expression of a matching gene. This is RNA interference (RNAi), recently discovered in C. elegans. a. Injecting dsRNA into adult worms results in specific loss of the corresponding mRNA in the worm and its progeny. b. RNAi also occurs in many other organisms, ...
... 1. Small dsRNA fragments can silence the expression of a matching gene. This is RNA interference (RNAi), recently discovered in C. elegans. a. Injecting dsRNA into adult worms results in specific loss of the corresponding mRNA in the worm and its progeny. b. RNAi also occurs in many other organisms, ...
The population dynamics during evolution under
... unknown how this might affect the activity of the gene product. The GPB2 mutation in M5 was caused by the insertion and of a Ty1 element in the coding region of the gene, likely inactivating its gene product. In addition, a frame shift mutation was observed in RIM15 in M4, also likely rendering its ...
... unknown how this might affect the activity of the gene product. The GPB2 mutation in M5 was caused by the insertion and of a Ty1 element in the coding region of the gene, likely inactivating its gene product. In addition, a frame shift mutation was observed in RIM15 in M4, also likely rendering its ...
The Mobile Genetic Element Alu in the Human Genome
... enetic material has been traditionally envisioned as relatively static with the exception of occasional, often deleterious mutations. The sequence DNA-toRNA-to-protein represented for many years the central dogma relating gene structure and function. Recently, the field of molecular genetics has pro ...
... enetic material has been traditionally envisioned as relatively static with the exception of occasional, often deleterious mutations. The sequence DNA-toRNA-to-protein represented for many years the central dogma relating gene structure and function. Recently, the field of molecular genetics has pro ...
Molecular Genetics of Autosomal-Dominant Demyelinating Charcot
... appeared describing a large segmental duplication within band 17p11.2, involving about 1.4 Mb of DNA (Lupski et al., 1991; Raeymaekers et al., 1991). The complete PMP22 gene was mapped within the duplicated region and the finding that point mutations in PMP22 also caused CMT1A confirmed that PMP22 w ...
... appeared describing a large segmental duplication within band 17p11.2, involving about 1.4 Mb of DNA (Lupski et al., 1991; Raeymaekers et al., 1991). The complete PMP22 gene was mapped within the duplicated region and the finding that point mutations in PMP22 also caused CMT1A confirmed that PMP22 w ...
Etiology : cytogenetics and microdeletions - HAL
... an apparently balanced translocation [Vissers and others 2004]. A more recent example is a collaborative work leading to the identification of a new gene (MEF2C) involved in a specific form of mental retardation. In this case, array CGH led to the characterization of a minimal common deleted region ...
... an apparently balanced translocation [Vissers and others 2004]. A more recent example is a collaborative work leading to the identification of a new gene (MEF2C) involved in a specific form of mental retardation. In this case, array CGH led to the characterization of a minimal common deleted region ...
A series of promoters for constitutive expression of heterologous
... expression vectors, and its transcription level was compared with that of the nmt1 promoter in some experiments (reviewed by Siam et al., 2004)). Although its expression is thought to be constitutive, it is not fully known how much its transcriptional activity varies among different media. Furthermo ...
... expression vectors, and its transcription level was compared with that of the nmt1 promoter in some experiments (reviewed by Siam et al., 2004)). Although its expression is thought to be constitutive, it is not fully known how much its transcriptional activity varies among different media. Furthermo ...
nar-02451-data-e-201
... include names/symbols of genes, diseases, methylation words, species, evidence sentences that include the association, PubMed Central ID of the article where the sentence is mentioned, PubMed ID of the abstract where the association is mentioned, and a confidence score generated by DEMGD system. The ...
... include names/symbols of genes, diseases, methylation words, species, evidence sentences that include the association, PubMed Central ID of the article where the sentence is mentioned, PubMed ID of the abstract where the association is mentioned, and a confidence score generated by DEMGD system. The ...
chapter 3 transmission genetics – chromosomes, recombination and
... allele at a locus on each of the homologous chromosomes are homozygous (e.g. DD and dd), whereas those with a different allele on each homologous chromosome are heterozygous (e.g. Dd). Mendel further hypothesized that one unit factor (i.e. allele) is dominant to the other recessive factor (i.e. the ...
... allele at a locus on each of the homologous chromosomes are homozygous (e.g. DD and dd), whereas those with a different allele on each homologous chromosome are heterozygous (e.g. Dd). Mendel further hypothesized that one unit factor (i.e. allele) is dominant to the other recessive factor (i.e. the ...
Use of Recombinant Adenovirus for Metabolic Engineering of
... DNA technology, it became apparent that this essential property of viruses might be exploited for the creation of efficient gene transfer vectors. The viral genome can consist of RNA, in the case of retroviruses, or of DNA. Research into the life cycle and biological properties of RNA and DNA viruse ...
... DNA technology, it became apparent that this essential property of viruses might be exploited for the creation of efficient gene transfer vectors. The viral genome can consist of RNA, in the case of retroviruses, or of DNA. Research into the life cycle and biological properties of RNA and DNA viruse ...
Transgenic approaches to microbial disease resistance in crop
... means to achieve increased disease resistance for many years. The enzymatically active antimicrobial proteins include chitinases, glucanases and lysozymes. Chitinases and glucanases are capable of degrading fungal cell wall components, and in vitro, some of these enzymes display strong antifungal ac ...
... means to achieve increased disease resistance for many years. The enzymatically active antimicrobial proteins include chitinases, glucanases and lysozymes. Chitinases and glucanases are capable of degrading fungal cell wall components, and in vitro, some of these enzymes display strong antifungal ac ...
No Slide Title
... Does the organism fall in the expected taxonomic domain of the pathway? Is this pathway part of a variant set, and, if so, is there more evidence for some other variant? If there is no unique enzyme: Is there evidence for more than one enzyme? If a biosynthetic pathway, is there evidence for fin ...
... Does the organism fall in the expected taxonomic domain of the pathway? Is this pathway part of a variant set, and, if so, is there more evidence for some other variant? If there is no unique enzyme: Is there evidence for more than one enzyme? If a biosynthetic pathway, is there evidence for fin ...
View/Open
... rather than two leads to an increase in placental size, the underlying mechanism is still to be determined [37]. In mice and cattle, accelerated development is already evident in XY blastocysts; cell division among male embryos occurs more rapidly than in female embryos [38] and, in humans, boys gro ...
... rather than two leads to an increase in placental size, the underlying mechanism is still to be determined [37]. In mice and cattle, accelerated development is already evident in XY blastocysts; cell division among male embryos occurs more rapidly than in female embryos [38] and, in humans, boys gro ...
Marine integrons containing novel integrase genes
... response to changing conditions. As it is the closest gene to the promoter, Pc, its expression level is the highest among other integron-associated gene cassettes (Collis and Hall, 1995). Thus, this gene cassette is a good target to find new strongly expressed adaptive genes in metagenomes (Huang et ...
... response to changing conditions. As it is the closest gene to the promoter, Pc, its expression level is the highest among other integron-associated gene cassettes (Collis and Hall, 1995). Thus, this gene cassette is a good target to find new strongly expressed adaptive genes in metagenomes (Huang et ...
The common bean growth habit gene PvTFL1y is a
... greenhouse with natural day length and an average temperature of 24°C. Arabidopsis was grown in a growth chamber at 24°C under the condition of 16 h of 120 lE m-2 s-1 light and 8 h of darkness. Arabidopsis was chosen for the transformation species because the PvTFL1y gene was initially identified du ...
... greenhouse with natural day length and an average temperature of 24°C. Arabidopsis was grown in a growth chamber at 24°C under the condition of 16 h of 120 lE m-2 s-1 light and 8 h of darkness. Arabidopsis was chosen for the transformation species because the PvTFL1y gene was initially identified du ...
Estonian HumanGenesResearchAct.
... tissue sample, the description of his or her state of health and his or her genealogy and shall deliver the personal data of the gene donor, the tissue sample, the description of his or her state of health and his or her genealogy to the chief processor or an authorised processor designated by the c ...
... tissue sample, the description of his or her state of health and his or her genealogy and shall deliver the personal data of the gene donor, the tissue sample, the description of his or her state of health and his or her genealogy to the chief processor or an authorised processor designated by the c ...
The genetics of self- incompatibility in white clover
... other species. The genes involved encode highly polymorphic RNases (called S-RNases) with two hypervariable regions (HVa and HVb) and five highly conserved regions (C1 to C5). These S-RNases are thought to cause premature termination of the pollen tube in incompatible reactions by degradation of rib ...
... other species. The genes involved encode highly polymorphic RNases (called S-RNases) with two hypervariable regions (HVa and HVb) and five highly conserved regions (C1 to C5). These S-RNases are thought to cause premature termination of the pollen tube in incompatible reactions by degradation of rib ...
Oakley
... occur by chance rather easily [26]. A second mechanism for the structural replication of eyes could be quantitative effects on a patterning process. In other words, replication can be caused by a periodic processing phenomenon, whereby one process generates an array of structures. The facets of comp ...
... occur by chance rather easily [26]. A second mechanism for the structural replication of eyes could be quantitative effects on a patterning process. In other words, replication can be caused by a periodic processing phenomenon, whereby one process generates an array of structures. The facets of comp ...
Linkage, Recombination, and the Mapping of Genes on Chromosomes
... • Mitotic recombination: Rarely, recombination occurs during mitosis. In multicellular organisms, mitotic recombination can produce genetic mosaicism in which different cells have different genotypes. ...
... • Mitotic recombination: Rarely, recombination occurs during mitosis. In multicellular organisms, mitotic recombination can produce genetic mosaicism in which different cells have different genotypes. ...
Report - TrSys - Jacobs University
... In addition, the arrangement of the amino acids is very much in line with the so-called Taylor classification. In the second part of the research, we have focused on investigating the relationship between Shannon and Boltzmann entropies using the complete genome sequence of the bacteria E. coli. The ...
... In addition, the arrangement of the amino acids is very much in line with the so-called Taylor classification. In the second part of the research, we have focused on investigating the relationship between Shannon and Boltzmann entropies using the complete genome sequence of the bacteria E. coli. The ...
5 Genetic Analysis of Kidney Disease in Mice
... examples from several phenotypes. We begin by selecting QTL found in three or more crosses that also had a concordant human QTL. We first narrowed the region by comparative genomics if possible and then by statistically combining the crosses. Next, we used a dense SNP database to reduce the regions ...
... examples from several phenotypes. We begin by selecting QTL found in three or more crosses that also had a concordant human QTL. We first narrowed the region by comparative genomics if possible and then by statistically combining the crosses. Next, we used a dense SNP database to reduce the regions ...
Identification of novel endogenous antisense transcripts by DNA
... We attempted to validate the expression of two candidate conserved NATs (antisense of Acaa1b and Aard) by performing Northern and in situ hybridization (ISH) analyses. Whereas human ACAA1 (acetyl-Coenzyme A acyltransferase 1) overlaps with DLEC1 (deleted in lung and esophageal cancer 1) in a tail-to ...
... We attempted to validate the expression of two candidate conserved NATs (antisense of Acaa1b and Aard) by performing Northern and in situ hybridization (ISH) analyses. Whereas human ACAA1 (acetyl-Coenzyme A acyltransferase 1) overlaps with DLEC1 (deleted in lung and esophageal cancer 1) in a tail-to ...
Somatic MEN1 gene mutation does not contribute
... discrepancy could have been explained by mutation(s) affecting the transcription level of the MEN1 gene. Therefore, we decided to sequence exon 1 and promoter but this experiment failed to reveal any mutation. While this work was in progress Prezant et al. also addressed this question by studying ME ...
... discrepancy could have been explained by mutation(s) affecting the transcription level of the MEN1 gene. Therefore, we decided to sequence exon 1 and promoter but this experiment failed to reveal any mutation. While this work was in progress Prezant et al. also addressed this question by studying ME ...
- Opus: Online Publications Store
... incomplete, since these only show pC,U becomes smaller due to a greatly increased mutational and recombinational robustness, leaving it still unclear whether or not recombination is able to retain sexual lineages in C, since pC,F and pF,C are largely unknown. Here we report the discovery of a new po ...
... incomplete, since these only show pC,U becomes smaller due to a greatly increased mutational and recombinational robustness, leaving it still unclear whether or not recombination is able to retain sexual lineages in C, since pC,F and pF,C are largely unknown. Here we report the discovery of a new po ...
MALE STERILITY - public.iastate.edu
... 3. Most revertants show that T-urf13 is deleted from mitochondrial genome by recombination, resulting in a simultaneous loss of cms and disease susceptibility; some revertants due to mutations (frameshift mutation or premature stop codon) in T-urf13 that make non-functional URF13 protein. These data ...
... 3. Most revertants show that T-urf13 is deleted from mitochondrial genome by recombination, resulting in a simultaneous loss of cms and disease susceptibility; some revertants due to mutations (frameshift mutation or premature stop codon) in T-urf13 that make non-functional URF13 protein. These data ...
Genome evolution
Genome evolution is the process by which a genome changes in structure (sequence) or size over time. The study of genome evolution involves multiple fields such as structural analysis of the genome, the study of genomic parasites, gene and ancient genome duplications, polyploidy, and comparative genomics. Genome evolution is a constantly changing and evolving field due to the steadily growing number of sequenced genomes, both prokaryotic and eukaryotic, available to the scientific community and the public at large.