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Supplementary Information
Supplementary Information

... CpG dinucleotide, along with its relative distance to the transcription start site and the oligomer DNA sequences are provided. Finally, the CpG island status of the genomic locus containing each CpG dinucleotide is measured using a relaxed version of the Takai and Jones CpG Island criteria – althou ...
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... To understand the relationship between the structure and function of primate neocortical areas at a molecular level, we have been screening for genes differentially expressed across macaque neocortical areas by restriction landmark cDNA scanning (RLCS). Here, we report enriched expression of the par ...
Multiple testing
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... profiles sorted according to some criterion (e.g. the significance of a t-statistics). We would like to select the set of genes considered as significant (e.g. to establish a signature enabling to predict cancer type). Question q Where should we set the limit ? Classical approach: select all genes p ...
Genetics Study Guide
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Chapter 1 - Online Open Genetics
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The emergence of humanevolutionary medical genomics
The emergence of humanevolutionary medical genomics

... across the genome (e.g. Manolio and Collins 2009), has been the discovery and characterization of disease risk alleles, to account for heritable risk, infer the causes of polygenic disease at the levels of development, physiology, and pathways, and guide strategies for treatment and prevention. Vuln ...
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Meiosis and mitosis - The Open University
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... Living organisms use the components of the world around themselves and convert these into their own living material. An acorn grows into an oak tree using only water, oxygen, carbon dioxide, some inorganic materials from the soil, and light energy. Similarly a human baby grows into an adult by diges ...
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Redgrave - people.vcu.edu
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Pole Region-Dependent Repression of the Drosophila Gap Gene
Pole Region-Dependent Repression of the Drosophila Gap Gene

... by maternal effect genes acting at the poles. The formation of the Kf protein domain may involve ubiquitous activation of Kr gene expression which, however, is limited by regionspecific repression through the action of the maternal anterior and posterior pattern organizer genes. In addition, the for ...
Introduction: - Statistical Science
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... optimistic results when assessing significance. This may lead to too many sets passing an FDR cutoff of 0.25. For example, the table shows the differences between phenotype label and gene tag permutations for the Gender dataset example. The large number of gene sets passing the test using gene tag p ...
in plant physiology
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... 4. The large transcription complex in higher plant chloroplasts Two types of PEP-containing preparation have been biochemically isolated in mustard and Arabidopsis: soluble RNA polymerase (sRNAP) and plastid transcriptionally active chromosome (pTAC) attached to chloroplast membranes (Hess and Borne ...
Depth-stratified functional and taxonomic niche
Depth-stratified functional and taxonomic niche

... PCs are exclusive and core to the photic and aphotic zones, respectively). Taxonomic annotation suggested that tailed phages are ubiquitous, but not abundant (o5% of PCs) and revealed depthrelated taxonomic patterns. Functional annotation, coupled with extensive analyses to document non-viral DNA co ...
Exploiting Differential Gene Expression and Epistasis to Discover
Exploiting Differential Gene Expression and Epistasis to Discover

... Soil water availability represents one of the most important selective agents for plants in nature and the single greatest abiotic determinant of agricultural productivity, yet the genetic bases of drought acclimation responses remain poorly understood. Here, we developed a systems-genetic approach ...
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Biology and consumer behaviour

Consumer behaviour is the study of the motivations surrounding a purchase of a product or service. It has been linked to the field of psychology, sociology and economics in attempts to analyse when, why, where and how people purchase in the way that they do. However, little literature has considered the link between our consumption behaviour and the basics of our being, our biology. Segmentation by biological driven demographics such as sex and age are already popular and pervasive in marketing. As more knowledge and research is known, targeting based on a consumers biology is of growing interest and use to marketers.As human machines being made up of cells controlled by our brain to influence aspects of our behaviour, there must be some influence of biology on our consumer behaviour and how we purchase as well. The nature versus nurture debate is at the core of how much biology influences these buying decisions, because it argues the extent to which biological factors influence what we do, and how much is reflected through environmental factors. Neuromarketing is of interest to marketers in measuring the reaction of stimulus to marketing. Even though we know there is a reaction, the question of why we consume the way we do still lingers, but it is a step in the right direction. Biology helps to understand consumer behaviour as it influences consumption and aids in the measurement of it.Lawson and Wooliscroft (2004) drew the link between human nature and the marketing concept, not explicitly biology, where they considered the contrasting views of Hobbes and Rousseau on mankind. Hobbes believed man had a self-serving nature whereas Rousseau was more forgiving towards the nature of man, suggesting them to be noble and dignified. Hobbes saw the need for a governing intermediary to control this selfish nature which provided a basis for the exchange theory, and also links to Mcgregor’s Theory of X and Y, relevant to management literature. He also considered cooperation and competition, relevant to game theory as an explanation of man’s motives and can be used for understanding the exercising of power in marketing channels. Pinker outlines why the nature debate has been suppressed by the nurture debate in his book The Blank Slate.
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