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Population-Based Resequencing Reveals That the Flowering Time
Population-Based Resequencing Reveals That the Flowering Time

... A monophyletic origin for barley, with a single domestication in the Israel–Jordan region, was initially suggested by amplified fragment length polymorphism analysis and haplotype data from the gene Bkn-3 (Badr et al. 2000), but polyphyletic origins have also been proposed (Kolodinska et al. 2004; M ...
Information about mosaic Neurofibromatosis type 2
Information about mosaic Neurofibromatosis type 2

... has a gene change that tends to develop a milder course of generalised NF2 or whether they could have a mosaic form. It is also important to be certain that the tumours identified are consistent with a diagnosis of NF2. The overwhelming majority of people who develop a tumour on one hearing nerve wi ...
Neurogenetics User Manual
Neurogenetics User Manual

... *Unless otherwise stated Sanger and Next Generation Sequencing (NGS) is of all coding exons and intron /exon boundaries and dosage analysis is by MLPA of all coding exons. ** All prices quoted are for NHS routine postnatal diagnostic tests, please contact the laboratory for price details on all othe ...
Mice 2 NZW)F Genetic Complementation in Female (BXSB ×
Mice 2 NZW)F Genetic Complementation in Female (BXSB ×

... for disease acceleration (16, 17), and double bone marrow chimera experiments using mixtures of Yaa⫹ and Yaa⫺ cells demonstrated selective production of anti-DNA and hypergammaglobulinemia by Yaa⫹ B cells (18). The Ab promoting effect of the Yaa gene was observed not only for self Ags, but also for ...
trans - bioRxiv
trans - bioRxiv

... significantly longer, and such alleles are expected to contribute relatively little to adaptive differences (i.e. ...
A Bayesian Network Classification Methodology for Gene
A Bayesian Network Classification Methodology for Gene

... nondescendants conditionally independent. It follows from these conditional independence assertions and the laws of probability that once a conditional distribution is associated with each node, specifying the probability that the node assumes a given value conditioned on the values assumed by the n ...
Waddington`s Legacy in Development and
Waddington`s Legacy in Development and

... genetic assimilation were the platform from lasted the test of time less well. I consider which Waddington launched his attacks on each of these in turn to provide a lexicon prevailing evolutionary theory (Wadding- of Waddington's legacy. ton, 1942). Much of his energies throughout the 1950s were de ...
Tandem Genetic Duplications in Phage and Bacteria
Tandem Genetic Duplications in Phage and Bacteria

... or to further amplification (i.e. triplication) of the chromosomal segment. The events causing this instability are depicted in Figure 3 as recombinational events between nascent daughter chromosomes. Alternatively, loss of the duplication could also be imagined to occur by a reciprocal exchange bet ...
Protocol: Genome-scale CRISPR-Cas9 Knockout
Protocol: Genome-scale CRISPR-Cas9 Knockout

... Programmable nucleases have emerged as a promising new genetic perturbation technology capable of precisely recognizing and cleaving target DNA17-19. Particularly, the RNA-guided endonuclease Cas9 from the microbial immune system CRISPR (clustered regularly interspaced short palindromic repeat) has ...
Chapter 4: EXTENSIONS OF MENDELIAN INHERITANCE
Chapter 4: EXTENSIONS OF MENDELIAN INHERITANCE

... Though dominant mutant alleles are much less common than recessive alleles, they do occur in natural populations. How can a mutant allele be dominant over a wild-type allele? Three explanations account for most dominant mutant alleles: a gainof-function mutation, a dominant-negative mutation, or hap ...
Protocol: Genome-scale CRISPR-Cas9 Knockout
Protocol: Genome-scale CRISPR-Cas9 Knockout

... Programmable nucleases have emerged as a promising new genetic perturbation technology capable of precisely recognizing and cleaving target DNA17-19. Particularly, the RNA-guided endonuclease Cas9 from the microbial immune system CRISPR (clustered regularly interspaced short palindromic repeat) has ...
Expression of Allene Oxide Synthase Determines - Bio
Expression of Allene Oxide Synthase Determines - Bio

... PIN II (Fig. 4a). When plants were exposed to trans-2hexenal or cis-3-hexenal in the presence of MeJA, PIN II expression was induced to similar levels as when MeJA was present alone (Fig. 4b). Although products of HPL did not affect the expression of AOS or PIN II, they did induce expression of the ...
SCI 30 UA CH 2.2 Inheritance
SCI 30 UA CH 2.2 Inheritance

... You have probably been told that you have characteristics similar to another member of your family. Perhaps someone has said that you have your mother’s hair, your father’s eyes, or that you inherited a trait from one of your grandparents. You might have compared your own characteristics to other fa ...
Boundary elements and nuclear organization
Boundary elements and nuclear organization

... in Grewal and Moazed, 2003). On the other hand, the euchromatic or transcriptionally competent state is associated with hyperacetylation of H3 lysines 9 and 14 and methylation of H3 lysine 4. Hyperacetylation of histones is thus correlated with transcriptional activation and is thought to aid in the ...
In the near future, EU thresholds for adventitious
In the near future, EU thresholds for adventitious

... Impurity testing in seeds has traditionally been done using either single or sequential seed-pool tests. From an analytical seed sample (e.g. 3000 seeds) equal seed pools are made and analysed individually for the trait of interest. Using binomial statistics, the number of seed pools positive for th ...
basic of the genetic
basic of the genetic

... • GENOTYPE = complex of all hereditary information of organism (all genes) • PHENOTYPE = complex of visible outward signs and characters, outer demonstration of the genotype • ALLELE = one form of the gene • HOMOZYGOUS = organism, which from perspective of selected gene includes couple of alleles wi ...
The Parasitic Wasp`s Secret Weapon
The Parasitic Wasp`s Secret Weapon

... that polydnaviral genes are active within 30 minutes of oviposition. By this time viral particles have spread throughout the host, entering cells, including hemocytes. In our tobacco hornworm system, we have also shown that at least one polydnavirus-encoded protein is produced inside host hemocytes ...
Harrisslides
Harrisslides

Exome sequencing as a tool for Mendelian disease gene discovery
Exome sequencing as a tool for Mendelian disease gene discovery

... of the observed heritability of the trait under study 4,5. Furthermore, little is known about the extent to which rare alleles contribute to the heritability of complex traits6. Since 2005, next-generation DNA sequencing platforms have become widely available, reducing the cost of DNA sequencing by ...
genomebiology.com
genomebiology.com

... revealed that TEs are less likely to be fixed within transcribed regions relative to orthologous regions in human and mouse [16]. In G. gallus, D. rerio and C. intestinalis, 33.2%, 47.3% and 39.4% of TEs reside within introns, respectively, whereas in the human genome, approximately 60% of TEs resid ...
Vocabulary Definitions
Vocabulary Definitions

Genetic studies of psoriasis and psoriatic arthritis
Genetic studies of psoriasis and psoriatic arthritis

... PSORS5 yielded no significant association. It is therefore unlikely that they harbor the genetic cause of psoriasis at this locus. Fine-mapping of the PSORS5 region revealed both point-wise and haplotype associations that might contribute to psoriasis susceptibility. The only gene within this region ...
Transcription regulation of the Escherichia coli pcnB gene coding for
Transcription regulation of the Escherichia coli pcnB gene coding for

... rapidly changing environmental conditions (SzalewskaPalasz et al. 2007b). There are two major eVectors of the stringent response. The Wrst one is a couple of two speciWc nucleotides, guanosine tetraphosphate (ppGpp) and guanosine pentaphosphate (pppGpp), collectively called (p)ppGpp and rapidly prod ...
Animal breeding
Animal breeding

... collections of pedigrees. What are the rules of transmission (for the population) in this case? What happens to the frequencies of alleles from one generation to the next? What about the frequency of genotypes? The machinery of popoulation genetics provides these answers, extending the Mendelian rul ...
Aster Yellows - Publications Centre
Aster Yellows - Publications Centre

... Camelina is quite susceptible to aster yellow. However, preliminary research shows potential for some differences between varieties. Symptoms include stunting, greenish-yellow or reddish-purple leaves, stems, and pods, and distorted inflorescences. ...
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History of genetic engineering

Genetic modification caused by human activity has been occurring since around 12,000 BC, when humans first began to domesticate organisms. Genetic engineering as the direct transfer of DNA from one organism to another was first accomplished by Herbert Boyer and Stanley Cohen in 1973. Advances have allowed scientists to manipulate and add genes to a variety of different organism and induce a range of different effects. Since 1976 the technology has been commercialised, with companies producing and selling genetically modified food and medicine.
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