5. Thrombocytopenia
... secondary to a variety of conditions. Begins with extrinsic (release of tissue factor) and intrinsic (factor XII activation) clotting cascade activation. Both pathways cause platelet consumption and thrombi formation leading to thrombocytopenia. ...
... secondary to a variety of conditions. Begins with extrinsic (release of tissue factor) and intrinsic (factor XII activation) clotting cascade activation. Both pathways cause platelet consumption and thrombi formation leading to thrombocytopenia. ...
Autoimmunity to glomerular antigens in
... that mesangial IgG or IgM deposits may be a necessary cofactor for initiation or amplification of injury [6,7]. Despite an extensive search, no specific bacterial, viral or food antigen has been identified [7], nor do IgA-containing immune complexes found in sera correlate with either clinical featu ...
... that mesangial IgG or IgM deposits may be a necessary cofactor for initiation or amplification of injury [6,7]. Despite an extensive search, no specific bacterial, viral or food antigen has been identified [7], nor do IgA-containing immune complexes found in sera correlate with either clinical featu ...
Stress Hormone and Skin Disease
... by the finding that activation of the HPA axis by stress aggravates the symptoms, mainly by inducing a shift toward Th2 cell phenotype. After stress, blunted HPA axis responsiveness and increased reactivity of the sympathetic adrenomedullary system in atopic patients was demonstrated (Buske-Kirschba ...
... by the finding that activation of the HPA axis by stress aggravates the symptoms, mainly by inducing a shift toward Th2 cell phenotype. After stress, blunted HPA axis responsiveness and increased reactivity of the sympathetic adrenomedullary system in atopic patients was demonstrated (Buske-Kirschba ...
Cord Blood Transplantation: from the basics to what`s new
... • Impaired allogeneic activation with subsequent decreased production of interferon-γ • Defective Th1 responses of CB T-cells related to differential expression and activation of transcription factors • Impaired cord blood dendritic cell maturation and cytokine production ...
... • Impaired allogeneic activation with subsequent decreased production of interferon-γ • Defective Th1 responses of CB T-cells related to differential expression and activation of transcription factors • Impaired cord blood dendritic cell maturation and cytokine production ...
immunochemical mechanisms involved in penicillin hypersensitivity
... (1) Benzylpenicilloyl-specific antibodies were detected by direct skin tests (Levine and Ovary, 1961; Levine and Price, 1964; Parker, Shapiro, Kern and Eisen, 1962) and by passive transfer techniques (Siegal and Levine, 1964). Skin test reagents which can be used for detection of benzylpenicilloyl ( ...
... (1) Benzylpenicilloyl-specific antibodies were detected by direct skin tests (Levine and Ovary, 1961; Levine and Price, 1964; Parker, Shapiro, Kern and Eisen, 1962) and by passive transfer techniques (Siegal and Levine, 1964). Skin test reagents which can be used for detection of benzylpenicilloyl ( ...
Human T lymphotropic virus type 1 uveitis
... observation was recorded even in the HTLV-I less endemic Kurume, although the seroprevalence in each group was lower than that in Miyakonojo (Table 1). The odds ratio was computed as an estimate ofrelative risk of HTLV-I infection in the three groups (Table 1). In younger patients (20-49 years), the ...
... observation was recorded even in the HTLV-I less endemic Kurume, although the seroprevalence in each group was lower than that in Miyakonojo (Table 1). The odds ratio was computed as an estimate ofrelative risk of HTLV-I infection in the three groups (Table 1). In younger patients (20-49 years), the ...
Lymphoid follicles in (very) severe COPD: beneficial or harmful? REVIEW
... of B-cell follicles. As seen in other tissues, these follicles are the result of lymphoid neogenesis. The finding of oligoclonality in B-cell follicles in COPD suggests that they play a role in local antigen specific immune responses. To date, it is not known which antigens may be involved; microbia ...
... of B-cell follicles. As seen in other tissues, these follicles are the result of lymphoid neogenesis. The finding of oligoclonality in B-cell follicles in COPD suggests that they play a role in local antigen specific immune responses. To date, it is not known which antigens may be involved; microbia ...
RES-ML2-COPD_FINAL
... • “Danger hypothesis” by Matzinger: immune system is triggered not by the infective material, but by the cellular stress or tissue damage.1 • Three-step mechanisms leading to COPD: • Step 1: Activation of macrophages and neutrophils as initial response to cigarette smoke (a healthy smoker) • Step 2: ...
... • “Danger hypothesis” by Matzinger: immune system is triggered not by the infective material, but by the cellular stress or tissue damage.1 • Three-step mechanisms leading to COPD: • Step 1: Activation of macrophages and neutrophils as initial response to cigarette smoke (a healthy smoker) • Step 2: ...
Impact of Anti-Oxidized Low- Density Lipoprotein
... of guanine is linked to the 5-methyl group of an adjacent 3’-thymine [24-26]. The majority of these ROS species are produced at a low level by normal aerobic metabolism, and normal defense mechanisms of the cells destroy most of them. Normally, any lesion to cells is constantly repaired. However, un ...
... of guanine is linked to the 5-methyl group of an adjacent 3’-thymine [24-26]. The majority of these ROS species are produced at a low level by normal aerobic metabolism, and normal defense mechanisms of the cells destroy most of them. Normally, any lesion to cells is constantly repaired. However, un ...
Activation of an inflammatory response is context
... immune effectors in natural populations, rarely has ontogeny been taken into account in these studies. This is unfortunate, as there is evidence that not only does the immune system develop differently among taxonomic groups, but also that at an individual level, the ability to respond to immune cha ...
... immune effectors in natural populations, rarely has ontogeny been taken into account in these studies. This is unfortunate, as there is evidence that not only does the immune system develop differently among taxonomic groups, but also that at an individual level, the ability to respond to immune cha ...
Barrier-protective function of intestinal epithelial TLR2 Barrier
... Elke Cario Division of Gastroenterology & Hepatology University Hospital of Essen Essen, Germany ...
... Elke Cario Division of Gastroenterology & Hepatology University Hospital of Essen Essen, Germany ...
Three cases of oral syphilis – an overview
... with chronic hyperplastic candidosis, but no candidal hyphae were observed and the lesion did not respond to systemic fluconazole. Other possible differential diagnoses from a histopathological perspective were geographic tongue, oral psoriasis, Reiter’s syndrome, and finally syphilis. However the c ...
... with chronic hyperplastic candidosis, but no candidal hyphae were observed and the lesion did not respond to systemic fluconazole. Other possible differential diagnoses from a histopathological perspective were geographic tongue, oral psoriasis, Reiter’s syndrome, and finally syphilis. However the c ...
Primary Sjo¨gren`s syndrome: current and emergent
... and 21%, respectively. This suggests that anti- -fodrin antibodies seem to reflect non-organ-specific autoimmunity, and probably have a limited discriminatory value for the diagnosis of primary SS. Viruses. Hepatic viruses. The hepatitis C virus (HCV) is one of the most likely candidates as a potentia ...
... and 21%, respectively. This suggests that anti- -fodrin antibodies seem to reflect non-organ-specific autoimmunity, and probably have a limited discriminatory value for the diagnosis of primary SS. Viruses. Hepatic viruses. The hepatitis C virus (HCV) is one of the most likely candidates as a potentia ...
oHo - Bioaveda
... “When I contemplate the data exposed in this my book-chapter about olive oil, oleic acid, Immunology, Skin, and ‘oHo’ in our kidney patients1, I feel the need to remember all my teachers, and friends, in Immunology, Dermatology and Preventive Medicine: Prof. André Capron (Institute Pasteur, Lille, F ...
... “When I contemplate the data exposed in this my book-chapter about olive oil, oleic acid, Immunology, Skin, and ‘oHo’ in our kidney patients1, I feel the need to remember all my teachers, and friends, in Immunology, Dermatology and Preventive Medicine: Prof. André Capron (Institute Pasteur, Lille, F ...
Molluscum Contagiosum and Warts - American Academy of Family
... N), and imiquimod are approved for genital HPV. In addition to case reports, one study23 of 50 patients showed a 56 percent clearance rate with imiquimod. Imiquimod is more rapidly being adopted into clinical practice because of its easy application. It may be useful in nongenital HPV, but more stud ...
... N), and imiquimod are approved for genital HPV. In addition to case reports, one study23 of 50 patients showed a 56 percent clearance rate with imiquimod. Imiquimod is more rapidly being adopted into clinical practice because of its easy application. It may be useful in nongenital HPV, but more stud ...
NOD2 Variants and Antibody Response to Microbial Antigens in
... Serologic Analysis and Classification All blood samples were taken at the time of consent and enrollment. Sera were analyzed for expression of ASCA, anti-I2, and anti-OmpC in a blinded fashion by enzyme-linked immunosorbent assay (ELISA) as previously described.23,55 Antibody levels were determined ...
... Serologic Analysis and Classification All blood samples were taken at the time of consent and enrollment. Sera were analyzed for expression of ASCA, anti-I2, and anti-OmpC in a blinded fashion by enzyme-linked immunosorbent assay (ELISA) as previously described.23,55 Antibody levels were determined ...
Epithelial barrier and dendritic cell function in the intestinal mucosa
... Nevertheless, occludin-deficient mice are still able to form well-developed TJ strands and retain normal intestinal barrier integrity ...
... Nevertheless, occludin-deficient mice are still able to form well-developed TJ strands and retain normal intestinal barrier integrity ...
The Challenging Response of Physis to Inflammation
... which is produced in the liver, and which indicates chronic inflammation. Initially it is produced to fight infection, help clear away dead bacteria, and promote healing. As long as inflammation persists, blood levels of CRP remain high. If this condition is prolonged, it will likely play a role in ...
... which is produced in the liver, and which indicates chronic inflammation. Initially it is produced to fight infection, help clear away dead bacteria, and promote healing. As long as inflammation persists, blood levels of CRP remain high. If this condition is prolonged, it will likely play a role in ...
Management of Immune Thrombocytopenic Purpura in Adults
... with treatment. Clinical trials with numerous new agents are under way, which we hope will add more effective and targeted strategies to our therapeutic armamentarium. We describe a logical and structured approach to the clinical management of ITP in adults, based on a literature review and our pers ...
... with treatment. Clinical trials with numerous new agents are under way, which we hope will add more effective and targeted strategies to our therapeutic armamentarium. We describe a logical and structured approach to the clinical management of ITP in adults, based on a literature review and our pers ...
cord day
... – Complement dependent cell lysis – T cells, (B cells/NK cells/DCs at higher doses) ...
... – Complement dependent cell lysis – T cells, (B cells/NK cells/DCs at higher doses) ...
The Situation with Gluten
... them (not differentiating them), triggering autoimmune pathologies. A high level of cytokines is also found in patients suffering from Alzheimer's, Parkinson's, MS, ALS (amyotrophic lateral sclerosis) or Charcot disease, and even fromautism. Gluten in particular and a diet rich in carbohydrates in g ...
... them (not differentiating them), triggering autoimmune pathologies. A high level of cytokines is also found in patients suffering from Alzheimer's, Parkinson's, MS, ALS (amyotrophic lateral sclerosis) or Charcot disease, and even fromautism. Gluten in particular and a diet rich in carbohydrates in g ...
Autoimmune Hemolytic Anemia and Red Blood Cell Autoantibodies
... adsorption procedures to find the most compatible blood, a potential benefit when urgent transfusion is needed. Potential pitfalls occur if the patient has an unusual or rare genetic determinant not detected by the molecular assay. However, given the difficulty in phenotyping a patient’s RBCs serolo ...
... adsorption procedures to find the most compatible blood, a potential benefit when urgent transfusion is needed. Potential pitfalls occur if the patient has an unusual or rare genetic determinant not detected by the molecular assay. However, given the difficulty in phenotyping a patient’s RBCs serolo ...
Cardiovascular homeostasis in health & disease
... • In Neurogenic shock, there is decreased sympathetic activity, therefore, increased vascular capacity. • Reason—Sudden loss of Vasomoter Tone resulting in massive dilation of veins therefore Venous pooling of blood and decreased venous return to heart. • Causes of Neurogenic shock • Brain injury • ...
... • In Neurogenic shock, there is decreased sympathetic activity, therefore, increased vascular capacity. • Reason—Sudden loss of Vasomoter Tone resulting in massive dilation of veins therefore Venous pooling of blood and decreased venous return to heart. • Causes of Neurogenic shock • Brain injury • ...
Risk factors for mortality caused by Staphylococcus
... Cancerologı́a (INC), in Bogotá, Colombia, and is the main etiological agent of bacteremia. This study describes the risk factors for mortality caused by S. aureus bacteremia in cancer patients. Methods: This is a retrospective, analytical, observational cohort study of 267 cases of bacteremia cause ...
... Cancerologı́a (INC), in Bogotá, Colombia, and is the main etiological agent of bacteremia. This study describes the risk factors for mortality caused by S. aureus bacteremia in cancer patients. Methods: This is a retrospective, analytical, observational cohort study of 267 cases of bacteremia cause ...
Efficacy of Human Immunoglobulin and Penicillin G in
... CFU, colony forming unit CSF, cerebrospinal fluid ELISA, enzyme-linked immunosorbent assay GBS, group B streptococcus ISG, immune serum globulin PMNs, polymorphonuclear leukocytes ...
... CFU, colony forming unit CSF, cerebrospinal fluid ELISA, enzyme-linked immunosorbent assay GBS, group B streptococcus ISG, immune serum globulin PMNs, polymorphonuclear leukocytes ...