• Study Resource
  • Explore
    • Arts & Humanities
    • Business
    • Engineering & Technology
    • Foreign Language
    • History
    • Math
    • Science
    • Social Science

    Top subcategories

    • Advanced Math
    • Algebra
    • Basic Math
    • Calculus
    • Geometry
    • Linear Algebra
    • Pre-Algebra
    • Pre-Calculus
    • Statistics And Probability
    • Trigonometry
    • other →

    Top subcategories

    • Astronomy
    • Astrophysics
    • Biology
    • Chemistry
    • Earth Science
    • Environmental Science
    • Health Science
    • Physics
    • other →

    Top subcategories

    • Anthropology
    • Law
    • Political Science
    • Psychology
    • Sociology
    • other →

    Top subcategories

    • Accounting
    • Economics
    • Finance
    • Management
    • other →

    Top subcategories

    • Aerospace Engineering
    • Bioengineering
    • Chemical Engineering
    • Civil Engineering
    • Computer Science
    • Electrical Engineering
    • Industrial Engineering
    • Mechanical Engineering
    • Web Design
    • other →

    Top subcategories

    • Architecture
    • Communications
    • English
    • Gender Studies
    • Music
    • Performing Arts
    • Philosophy
    • Religious Studies
    • Writing
    • other →

    Top subcategories

    • Ancient History
    • European History
    • US History
    • World History
    • other →

    Top subcategories

    • Croatian
    • Czech
    • Finnish
    • Greek
    • Hindi
    • Japanese
    • Korean
    • Persian
    • Swedish
    • Turkish
    • other →
 
Profile Documents Logout
Upload
Surgical Neurology International
Surgical Neurology International

... Over the past several decades we have learned a great deal about microglia and innate brain immunity. While microglia are the principle innate immune cells, other cell types also play a role, including invading macrophages, astrocytes, neurons, and endothelial cells. The fastest reacting cell is the ...
Erection - abuad lms
Erection - abuad lms

... which are amenable to treatment. Common physiological reasons include diabetes, kidney disease, chronic alcoholism, multiple sclerosis, atherosclerosis, vascular disease, and neurologic disease which collectively account for about 70 per-cents of ED cases. Some drugs used to treat other conditions, ...
Distribution of DRB1 and DQB1 HLA class II alleles in
Distribution of DRB1 and DQB1 HLA class II alleles in

... a marker of exposure and may not be responsible for the pathogenesis of the disease. Recently, activated CD4+ cells were demonstrated in the bronchial mucosa of these patients [32]. Also, the lymphocytes of some patients with WRCA showed proliferation when stimulated with PA-HSA conjugate suggesting ...
Pemphigus pathogenesis - Welcome!
Pemphigus pathogenesis - Welcome!

... -Initially 2 cycles of rituximab given once weekly for 3 weeks and IVIg given in the 4th week; followed by monthly infusion of rituximab and IVIg for 4 consecutive months -Of 11 patients, 9 had complete and rapid resolution of lesions and a clinical remission lasting an average of 31 months. All imm ...
IOSR Journal of Dental and Medical Sciences (IOSR-JDMS)
IOSR Journal of Dental and Medical Sciences (IOSR-JDMS)

... Following the guidelines given in this text, experience on dummies and performing the procedure under supervision this incidence will definitely come down to acceptable standards. Moreover this is a small study and definitive conclusion be drawn for from this. In general, unintended arterial punctur ...
- World Journal of Gastroenterology
- World Journal of Gastroenterology

... various reports showing an association of the ε4 allele with early onset of some autoimmune and neurodegenerative diseases[30,64,67,68]. The APOE ε4 allele is believed to be responsible for reducing high-density lipoprotein and increasing low-density lipoprotein in high-fat intake individuals[69], w ...
Characterisation of interleukin-10 expression on different vascular
Characterisation of interleukin-10 expression on different vascular

... (IL-10) on the endothelial cells in the nasal mucosa of allergic subjects. This endothelial IL-10 expression appeared to have a strong inverse correlation with the induced symptoms of allergic rhinitis [8]. In our previous study we did not explore potential mechanisms by which endothelial IL-10 expr ...
The Efficacy of Traditional Chinese Medicine on
The Efficacy of Traditional Chinese Medicine on

... will have more inflammatory related illnesses as well as side effects from medications that could increase costs both for the healthcare system and patient finances. This determination is primarily due to the rise in positive diagnosis in patients who have had symptoms but no actual prior diagnosis ...
投影片 1
投影片 1

... – WASp gene at Xp11.22p11.23 – Thrombocytopenia + small platelet (half size) + eczema + T-cell immunodeficiency – Normal or megakaryocyte mass – Increase destruction in spleen thrombocytopenia and decrease PLT size – Splenectomy definitely improves PLT counts in these pts, which frequently return ...
4. Treatment of pyoderma gangrenosum usually involves systemic
4. Treatment of pyoderma gangrenosum usually involves systemic

... The classic skin lesion of pyoderma gangrenosum usually begins with folliculocentric pustules or fluctuant nodules with an inflammatory halo, and expands peripherally to form an ulcer with sharply circumscribed violaceous raised edges [1]. Lesions typically affect the lower extremities and the trunk ...
Anti-Aging Benefits of Bovine Colostrum
Anti-Aging Benefits of Bovine Colostrum

... to amyloid plaques found in Alzheimer’s disease. Both amylin and amyloid are over-produced during the disease process, cross the blood brain barrier where they build up in brain tissue, and over time, lead to the loss of brain cells. Bovine colostrum supplementation as an adjunct to controlling bloo ...
Monocytes Are Major Players in the Prognosis and
Monocytes Are Major Players in the Prognosis and

... Background and Purpose—Monocytes participate in adaptive and innate immune responses. Monocyte numbers increase in patients with stroke associated infection (SAI) or severe stroke. Whether changes in monocytes are related to specific effects, or simply mark brain damage, remains unsettled. Methods—W ...
Full Text  - Avicenna Journal of Dental Research
Full Text - Avicenna Journal of Dental Research

... pylori interaction with surface epithelial cells develops direct cell damage or produces pro-inflammatory mediators (29). Secondly, H. pylori reaches the underlying mucosa, hence stimulates immune response, which in turn leads to liberation of different cytokines and oxygen radicals (30). The presen ...
MSM Immune Health Science Brief
MSM Immune Health Science Brief

... coordinate efforts are the cytokines, which include both pro-inflammatory and anti-inflammatory molecules. IL-1, IL-6, and TNF-α are the primary cytokines involved in the innate immune response and are predominately produced by macrophages. But many others are involved in the process including NF- K ...
Immunity and Gastrointestinal Disease: A Role for Lymphatic Vessels
Immunity and Gastrointestinal Disease: A Role for Lymphatic Vessels

... inflammation forming lymphoid aggregates, and creating a selfperpetuating feedback loop that prolongs the local immune response [48]. On the other hand, Jurisic et al. [49] found a significant increase in the severity of colonic inflammation in IL-10-deficient mice (that spontaneously develop IBD-li ...
Distinct cytokine profiles define clinical immune response to
Distinct cytokine profiles define clinical immune response to

... both TNF and IFN-γ have been associated with severe disease manifestations [9, 15]. Excessive TNF production may lead to severe anemia, acute respiratory distress and upregulation of endothelial adhesion molecule expression resulting in cerebral, malaria-related complications [9, 16, 17]. Studies in ...
Pediatric Neck Masses
Pediatric Neck Masses

... Second branchial cleft anomalies • Cyst presents as slow growing mass in upper neck • Often present into adulthood •Sinus or fistula can have skin pit anywhere along anterior border of SCM ...
Immunology Letters Complement and immune defense: From
Immunology Letters Complement and immune defense: From

... occurs and such reactions can lead to autoimmune disease. A defective host immune response results in attack on host surfaces and leads ultimately to autoimmune diseases [5]. Such defects can be caused by (i) inappropriate immune activation, i.e. activation at the wrong time, (ii) inappropriate deli ...
TLR2 and TLR4 expression on CD14++ and CD14+ monocyte
TLR2 and TLR4 expression on CD14++ and CD14+ monocyte

... or altered expression of cytokines and pattern-recognition receptors on monocytes may contribute to the development of the autoimmune type of diabetes mellitus (AD). Aims. We aimed to analyze the counts and proportions of the two main subtypes of monocyte cells, CD14++ and CD14+, and to look for pot ...
Fat Embolism - IMA Pathankot
Fat Embolism - IMA Pathankot

... "Disease with an undetermined Pathophysiology causes a non-specific treatment" ...
Benign Laryngeal Lesions
Benign Laryngeal Lesions

...  Phase asymmetry due to ball-valving and asymmetric edema ...
Fragile Skin: Benefit of Cosmeceuticals based on Rhealba® Oat
Fragile Skin: Benefit of Cosmeceuticals based on Rhealba® Oat

... Although in acne filaggrin expression seems to be augmented, in acne affected skin we curiously find different parameters typically associated with filaggrin function impairment: Yamamato et al. observed that patients with acne vulgaris exhibited markedly greater TEWL and lower skin hydration with a ...
Emerging drugs for asthma
Emerging drugs for asthma

... mepolizumab treatment of asthmatics not only reduced eosinophil numbers in the blood and sputum but also resulted in a significant reduction in asthma exacerbations. Both studies were randomized, double-blind, placebo-controlled, parallel-group studies that investigated the effects of monthly infus ...
Cytokine hypothesis of overtraining: a physiological adaptation to
Cytokine hypothesis of overtraining: a physiological adaptation to

... recruitment of specific white blood cells. Neutrophils represent the first wave of infiltrating cells and play a vital role in the “clean-up” process. Neutrophils predominate during the initial phase of acute inflammation but by 24 h are no longer active (86). Monocytes form the next line of defense ...
Humoral Sensitization Against Rejected Grafts
Humoral Sensitization Against Rejected Grafts

... the second graft against which the host has preexistent antibodies, helping to exclude high-risk transplants. In some cases we were not able to find HLA class I antibodies against specific alloantigens despite exposure of the recipient to foreign molecules. Whether an alloepitope will be presented b ...
< 1 2 3 4 5 6 7 8 9 10 ... 52 >

Pathophysiology of multiple sclerosis

Multiple sclerosis (MS) is a condition where the CNS of a person present a special kind of distributed glial scars (sclerosis) which are a remaining of a previous inflammatory demyelination. MS pathophysiology is complex and still under investigation and there is no agreement about its scope. Some authors consider it a pathological entity, while others consider it a clinical entity. From a pathological point of view, the demyelinating lesions can be classified as encephalomyelitis, and sometimes the disease is known as encephalomyelitis disseminata.There are two phases for how an unknown underlying condition may cause damage in MS: First some MRI-abnormal areas with hidden damage appear in the brain and spine (NAWM, NAGM, DAWM). Second, there are leaks in the blood–brain barrier where immune cells infiltrate causing the known demyelination and axon destruction. Some clusters of activated microglia, transection of axons and myelin degeneration is present before the BBB breaks down and the immune attack beginsPathophysiology is a convergence of pathology with physiology. Pathology is the medical discipline that describes conditions typically observed during a disease state; whereas physiology is the biological discipline that describes processes or mechanisms operating within an organism. Referring to MS, the physiology refers to the different processes that lead to the development of the lesions and the pathology refers to the condition associated with the lesions.
  • studyres.com © 2025
  • DMCA
  • Privacy
  • Terms
  • Report