Tung Tree DGAT1 and DGAT2 Have Nonredundant Functions in
... catalyzing the committed step: the transfer of a fatty acyl moiety from acyl-CoA to the sn-3 position of diacylglycerol (Kennedy, 1961). As such, DGAT plays an essential role in controlling both the quantitative (Ichihara et al., 1988) and qualitative (Vogel and Browse, 1996; He et al., 2004a) flux ...
... catalyzing the committed step: the transfer of a fatty acyl moiety from acyl-CoA to the sn-3 position of diacylglycerol (Kennedy, 1961). As such, DGAT plays an essential role in controlling both the quantitative (Ichihara et al., 1988) and qualitative (Vogel and Browse, 1996; He et al., 2004a) flux ...
Basement membrane matrices in mouse embryogenesis
... in early development and teratocarcinoma differentiation. In the early embryo a compartmentalization of newly formed cell types takes place immediately by formation of basement membranes The stage-specific developmental appearance of extracellular matrix molecules such as type IV collagen, laminin. ...
... in early development and teratocarcinoma differentiation. In the early embryo a compartmentalization of newly formed cell types takes place immediately by formation of basement membranes The stage-specific developmental appearance of extracellular matrix molecules such as type IV collagen, laminin. ...
Selective Cytotoxicity of Rhodium Metalloinsertors in Mismatch
... identically.32 It seems likely that such a perturbation of the double helix might have consequences within the cell. Of course, any potential agent must first reach its target before it may bind. Confocal microscopy and flow cytometry studies with [Ru(L)2dppz]2+ (dppz = dipyrido[3,2-a:2′,3′-c]phenaz ...
... identically.32 It seems likely that such a perturbation of the double helix might have consequences within the cell. Of course, any potential agent must first reach its target before it may bind. Confocal microscopy and flow cytometry studies with [Ru(L)2dppz]2+ (dppz = dipyrido[3,2-a:2′,3′-c]phenaz ...
Newly Synthesized Catalytic and Regulatory Components of
... critical assessment of any role for CAMP in regulating development and function of mammalian neurons, it must first be demonstrated that (1) developing neurons can synthesize CAMP, e.g., express adenylate cyclase (AC); (2) CAMP levels in the cell are sufficient to activate protein kinases; (3) such ...
... critical assessment of any role for CAMP in regulating development and function of mammalian neurons, it must first be demonstrated that (1) developing neurons can synthesize CAMP, e.g., express adenylate cyclase (AC); (2) CAMP levels in the cell are sufficient to activate protein kinases; (3) such ...
Nervous System
... • If membrane potential becomes less negative, it has depolarized • Graded (or proportional) to intensity of stimulation, meaning the greater the stimulation, the greater the depolarization • if the depolarization is great enough, reach threshold potential ...
... • If membrane potential becomes less negative, it has depolarized • Graded (or proportional) to intensity of stimulation, meaning the greater the stimulation, the greater the depolarization • if the depolarization is great enough, reach threshold potential ...
Green genes - DNA in (and out of) chloroplasts
... these still carry the regulatory DNA sequences that directed their transcription in chloroplasts but the genes are not transcribed in the nucleus because these sequences are not ‘recognised’ by nuclear proteins. Therefore, before a transferred chloroplast gene is expressed, it must acquire the corre ...
... these still carry the regulatory DNA sequences that directed their transcription in chloroplasts but the genes are not transcribed in the nucleus because these sequences are not ‘recognised’ by nuclear proteins. Therefore, before a transferred chloroplast gene is expressed, it must acquire the corre ...
PAR-1 activation by SFLLRNP decreases
... 2005). These modifications, made through retraction and/or degeneration, are responsible for establishing meaningful connections and are involved in neural plasticity (Luo and O’Leary, 2005). In developing systems, neurodegeneration is hypothesized to be accomplished through cell-intrinsic programs, ...
... 2005). These modifications, made through retraction and/or degeneration, are responsible for establishing meaningful connections and are involved in neural plasticity (Luo and O’Leary, 2005). In developing systems, neurodegeneration is hypothesized to be accomplished through cell-intrinsic programs, ...
The histidine triad protein Hint1 interacts with Pontin and Reptin and
... ATDC in this context is not clear, there is evidence that Hint1 plays a role in the radiation sensitivity of cells by repressing fos transcription (Choi et al., 2000). The association of Hint1 with cyclin-dependent kinase 7 (CDK7), furthermore, supports a function in growth control and transcription ...
... ATDC in this context is not clear, there is evidence that Hint1 plays a role in the radiation sensitivity of cells by repressing fos transcription (Choi et al., 2000). The association of Hint1 with cyclin-dependent kinase 7 (CDK7), furthermore, supports a function in growth control and transcription ...
The role of lipids in the biogenesis of integral membrane
... This lipid diversity is likely to be important to ensure the dynamic functioning of membranes under changing environmental conditions, and may also account for the differences in function that the various subcellular membranes have to fulfill. In addition to bulk bilayer lipids, specific lipids have ...
... This lipid diversity is likely to be important to ensure the dynamic functioning of membranes under changing environmental conditions, and may also account for the differences in function that the various subcellular membranes have to fulfill. In addition to bulk bilayer lipids, specific lipids have ...
Proteomics_12-8
... - scores from decoy comparison are included, which can provide some idea of the distribution of ‘incorrect’ scores -EM or Bayesian approaches can then estimate the proportion of correct vs. incorrect PSM … based on each PSM score, a posterior probability is calculated ...
... - scores from decoy comparison are included, which can provide some idea of the distribution of ‘incorrect’ scores -EM or Bayesian approaches can then estimate the proportion of correct vs. incorrect PSM … based on each PSM score, a posterior probability is calculated ...
Chemical genetics to chemical genomics: small
... techniques already? There are several advantages of chemical genetics over genetics. For example, small molecules most often induce their biological effect reversibly, due to metabolism or clearing. To do this genetically a conditional allele (gene mutation) is required, such as a temperature sensit ...
... techniques already? There are several advantages of chemical genetics over genetics. For example, small molecules most often induce their biological effect reversibly, due to metabolism or clearing. To do this genetically a conditional allele (gene mutation) is required, such as a temperature sensit ...
Motility and substratum adhesion of Dictyostelium wild
... and Tranquillo, 1993). In order to understand cell locomotion in terms of cytoskeletal dynamics and the forces generated by cytoskeletonmembrane coupling (Sackmann, 1994; Oliver et al., 1994), global methods of cell tracking have to be complemented by detailed studies at the single-cell level (Alt, ...
... and Tranquillo, 1993). In order to understand cell locomotion in terms of cytoskeletal dynamics and the forces generated by cytoskeletonmembrane coupling (Sackmann, 1994; Oliver et al., 1994), global methods of cell tracking have to be complemented by detailed studies at the single-cell level (Alt, ...
Proteins in Serum and Urine - Ústav lékařské biochemie a
... In a weakly acidic environment albumin behaves as a cation. It can react with anionic dyes yielding an albumin-dye complex. Binding of the dye is associated with a change in color. The reaction takes place in weakly acidic medium in the presence of surface-active substances. Organic dyes are used th ...
... In a weakly acidic environment albumin behaves as a cation. It can react with anionic dyes yielding an albumin-dye complex. Binding of the dye is associated with a change in color. The reaction takes place in weakly acidic medium in the presence of surface-active substances. Organic dyes are used th ...
Protein Folding
... protein folding. The surface is derived from a computer simulation of the folding of a highly simplified model of a small protein. The surface 'funnels' the multitude of denatured conformations to the unique native structure. The critical region on a simple surface such as this one is the saddle poi ...
... protein folding. The surface is derived from a computer simulation of the folding of a highly simplified model of a small protein. The surface 'funnels' the multitude of denatured conformations to the unique native structure. The critical region on a simple surface such as this one is the saddle poi ...
TOR SIGNALLING IN BUGS, BRAIN AND BRAWN
... TRRAP proteins; FRB, the binding site for FKBP12–rapamycin; HEAT, an amino-acid sequence motif that was first identified in huntingtin, elongation factor 3, regulatory A subunit of PP2A and TOR; KOG1, kontroller of growth 1. ...
... TRRAP proteins; FRB, the binding site for FKBP12–rapamycin; HEAT, an amino-acid sequence motif that was first identified in huntingtin, elongation factor 3, regulatory A subunit of PP2A and TOR; KOG1, kontroller of growth 1. ...
Chapter 9 Proteins - Angelo State University
... positive or negative charge, the like charges cause the molecules to repel one another, and they remain dispersed. ...
... positive or negative charge, the like charges cause the molecules to repel one another, and they remain dispersed. ...
Sensory Receptors
... • Warns of actual or impending tissue damage protective action • Stimuli include extreme pressure and temperature, histamine, K+, ATP, acids, and bradykinin • Impulses travel on fibers that release neurotransmitters glutamate and substance P • Some pain impulses are blocked by inhibitory ...
... • Warns of actual or impending tissue damage protective action • Stimuli include extreme pressure and temperature, histamine, K+, ATP, acids, and bradykinin • Impulses travel on fibers that release neurotransmitters glutamate and substance P • Some pain impulses are blocked by inhibitory ...
how cells obtain energy from food
... isomerase and dehydro genase-,lo indicate the type of reaction they catalyze. Although no molecular oxygen is used in glycolysis,oxidation occurs, in that electrons are removed by NAD+ (producing NADH) from some of the carbons derived from the glucose molecule. The stepwise nature of the process rel ...
... isomerase and dehydro genase-,lo indicate the type of reaction they catalyze. Although no molecular oxygen is used in glycolysis,oxidation occurs, in that electrons are removed by NAD+ (producing NADH) from some of the carbons derived from the glucose molecule. The stepwise nature of the process rel ...
The a-subunit of a heterotrimeric G-protein from
... G-proteins are composed of three different subunits, the a-, b-, and c-subunits. They are among the most important intracellular molecular switches used in the transduction of signals from the cell surface into the cell. They are activated by receptors with seven transmembranespans (7TMS ), and this ...
... G-proteins are composed of three different subunits, the a-, b-, and c-subunits. They are among the most important intracellular molecular switches used in the transduction of signals from the cell surface into the cell. They are activated by receptors with seven transmembranespans (7TMS ), and this ...
Cellular lipidomics
... inside of the membrane (Lisanti et al, 1994; Parton, 1994) or activated receptors, a lipid, like ceramide generated by signaling sphingomyelinases (Gulbins et al, 2004; London and London, 2004), or lipid-anchored proteins (Brügger et al, 2004). In lipid transport, the forming lipid domain must be s ...
... inside of the membrane (Lisanti et al, 1994; Parton, 1994) or activated receptors, a lipid, like ceramide generated by signaling sphingomyelinases (Gulbins et al, 2004; London and London, 2004), or lipid-anchored proteins (Brügger et al, 2004). In lipid transport, the forming lipid domain must be s ...
Analysis of the Nitrous Oxide Reduction Genes, nosZDFYL, of
... The structural gene, nosZ, for the monomeric N2O reductase has been cloned and sequenced from the denitrifying bacterium Achromobacter cycloclastes. The nosZ gene encodes a protein of 642 amino acid residues and the deduced amino acid sequence showed homology to the previously derived sequences for ...
... The structural gene, nosZ, for the monomeric N2O reductase has been cloned and sequenced from the denitrifying bacterium Achromobacter cycloclastes. The nosZ gene encodes a protein of 642 amino acid residues and the deduced amino acid sequence showed homology to the previously derived sequences for ...
Hemoglobin Lecture 2
... in the protein and is essential for function • steric relationships within Hb ensure that the heme group has appropriate reactivity • hemoglobin has quaternary structure which gives it unique O2 binding properties allosterism and cooperativity of binding • 2,3-bisphosphoglycerate is a regulatory mol ...
... in the protein and is essential for function • steric relationships within Hb ensure that the heme group has appropriate reactivity • hemoglobin has quaternary structure which gives it unique O2 binding properties allosterism and cooperativity of binding • 2,3-bisphosphoglycerate is a regulatory mol ...
Cell division in the green microalga Marvania
... the taxonomic delimitation of the order Chlorococcales. The ...
... the taxonomic delimitation of the order Chlorococcales. The ...
Signal transduction
Signal transduction occurs when an extracellular signaling molecule activates a specific receptor located on the cell surface or inside the cell. In turn, this receptor triggers a biochemical chain of events inside the cell, creating a response. Depending on the cell, the response alters the cell's metabolism, shape, gene expression, or ability to divide. The signal can be amplified at any step. Thus, one signaling molecule can cause many responses.