Modulation of T cell signaling by the actin cytoskeleton
... activation involves many spatially and temporally coordinated signaling processes on multiple time and length scales. There are three distinct stages during the activation process: T cell receptor (TCR) triggering, signal persistence and signal termination. A crawling T cell constantly scans the sur ...
... activation involves many spatially and temporally coordinated signaling processes on multiple time and length scales. There are three distinct stages during the activation process: T cell receptor (TCR) triggering, signal persistence and signal termination. A crawling T cell constantly scans the sur ...
Polarity and endocytosis: reciprocal regulation
... activity of specific proteins. Endocytosis begins at the plasma membrane, where transmembrane proteins such as receptors and other membrane-associated proteins cluster into invaginating clathrin-coated pits (CCP). This clustering is dependent on recognition of appropriate cargo proteins by adaptor p ...
... activity of specific proteins. Endocytosis begins at the plasma membrane, where transmembrane proteins such as receptors and other membrane-associated proteins cluster into invaginating clathrin-coated pits (CCP). This clustering is dependent on recognition of appropriate cargo proteins by adaptor p ...
Environmentally Sensitive Fluorescent Sensors Based on Synthetic Peptides Linköping University Post Print
... Moreover, synthetic peptides are robust, offer an even larger chemical versatility than recombinant proteins and are easily modified in a site-specific manner by means of orthogonal protection group strategies. Thus, peptides should have a great potential as components in molecular biosensors. This ...
... Moreover, synthetic peptides are robust, offer an even larger chemical versatility than recombinant proteins and are easily modified in a site-specific manner by means of orthogonal protection group strategies. Thus, peptides should have a great potential as components in molecular biosensors. This ...
5 Lecture (Bacteria Ch27)
... Name for a rod-shaped bacterium. Name for a comma-shaped bacterium. Name for a spiral shaped bacterium with many bends. • Name for a spiral shaped bacterium with only a few bends. • Name for a cluster of round bacteria. ...
... Name for a rod-shaped bacterium. Name for a comma-shaped bacterium. Name for a spiral shaped bacterium with many bends. • Name for a spiral shaped bacterium with only a few bends. • Name for a cluster of round bacteria. ...
Structure and Function of Membrane Proteins: Overview
... 2. They are always continuous, unbroken structures & thus form extensive interconnected networks within cell B. Due to flexibility of lipid bilayer, membranes are deformable & can change their overall shape (as in locomotion & cell division) C. Bilayer facilitates regulated fusion or budding of memb ...
... 2. They are always continuous, unbroken structures & thus form extensive interconnected networks within cell B. Due to flexibility of lipid bilayer, membranes are deformable & can change their overall shape (as in locomotion & cell division) C. Bilayer facilitates regulated fusion or budding of memb ...
Degradation signals within both terminal domains of the cauliflower
... (a) The UPR technique. Reference and test proteins are separated by a ubiquitin moiety. This fusion is cleaved by ubiquitin (Ub)-speci®c proteases at the Ub±test protein junction, yielding equimolar amounts of both proteins (Levy et al., 1996). For this study the system was adapted by using two stab ...
... (a) The UPR technique. Reference and test proteins are separated by a ubiquitin moiety. This fusion is cleaved by ubiquitin (Ub)-speci®c proteases at the Ub±test protein junction, yielding equimolar amounts of both proteins (Levy et al., 1996). For this study the system was adapted by using two stab ...
Proteins - Cathkin High School
... are regarded as being essential for humans although a further two are required in childhood. Some amino acids have more than one amino group or more than one carboxyl group and these allow chains to form branches. With twenty different amino acids joining in large numbers, it is possible to produce ...
... are regarded as being essential for humans although a further two are required in childhood. Some amino acids have more than one amino group or more than one carboxyl group and these allow chains to form branches. With twenty different amino acids joining in large numbers, it is possible to produce ...
Paramecium trichocysts isolated with their membranes are stable in
... swelling would then be to help disperse, propel or otherwise empty the contents of the vesicle outside the cell. ...
... swelling would then be to help disperse, propel or otherwise empty the contents of the vesicle outside the cell. ...
Chapter 1: The Microbial World and You
... organelles and indicate the function of each: plasma membrane, mitochondria, endoplasmic reticulum, ribosomes, Golgi bodies, plastids, vacuoles and nucleus. 2- Distinguish between prokaryotic and ...
... organelles and indicate the function of each: plasma membrane, mitochondria, endoplasmic reticulum, ribosomes, Golgi bodies, plastids, vacuoles and nucleus. 2- Distinguish between prokaryotic and ...
Chapter 17 Outline
... Included among the special senses are smell, taste, sight, hearing, and equilibrium. .In contrast to the general senses, the special senses have highly complex receptor organs. The detailed anatomy and physiology of the special senses are discussed. The development of the eyes and ears are also disc ...
... Included among the special senses are smell, taste, sight, hearing, and equilibrium. .In contrast to the general senses, the special senses have highly complex receptor organs. The detailed anatomy and physiology of the special senses are discussed. The development of the eyes and ears are also disc ...
Complete sequence analysis of the genome of the bacterium
... sequence similarities to genes or proteins from other organisms with known functions (e.g. ribosomal proteins) or at least known categories of function (e.g. proteins involved in cytadherence). Significant similarities to proteins without known function from other bacteria, mostly M.genitalium, were ...
... sequence similarities to genes or proteins from other organisms with known functions (e.g. ribosomal proteins) or at least known categories of function (e.g. proteins involved in cytadherence). Significant similarities to proteins without known function from other bacteria, mostly M.genitalium, were ...
Target Predictions using LINCS Data
... Specifically, the dataset contains experiments profiling the effects of 20,143 small-molecule compounds (including known drugs and pathway-specific tool compounds). In addition, there are 22,119 genetic constructs for over-expressing genes (gain-of-function) or knocking-down (KD) genes (lossof-funct ...
... Specifically, the dataset contains experiments profiling the effects of 20,143 small-molecule compounds (including known drugs and pathway-specific tool compounds). In addition, there are 22,119 genetic constructs for over-expressing genes (gain-of-function) or knocking-down (KD) genes (lossof-funct ...
Journal: Applied Microbiology and Biotechnology
... intracellular metabolites of adherent Madin Darby canine kidney (MDCK) cells during cultivation in a serum-containing and a serum-free medium. The cells, which originated from the same pre-culture, showed similar overall growth behavior and only slight differences in their demand for the substrates ...
... intracellular metabolites of adherent Madin Darby canine kidney (MDCK) cells during cultivation in a serum-containing and a serum-free medium. The cells, which originated from the same pre-culture, showed similar overall growth behavior and only slight differences in their demand for the substrates ...
Test File
... membrane-bound complexes collectively called the _______. These complexes pump _______ across the _______ membrane. 43. The _______ produced by this process drives a flow of these ions through a complex of proteins called _______ to produce ATP from ADP and Pi. Short Answer 44-48. Where in “typical” ...
... membrane-bound complexes collectively called the _______. These complexes pump _______ across the _______ membrane. 43. The _______ produced by this process drives a flow of these ions through a complex of proteins called _______ to produce ATP from ADP and Pi. Short Answer 44-48. Where in “typical” ...
Lysosomal biogenesis and function is critical for necrotic cell death
... deficiency (Table I). We conclude that suppression of necrosis by aspartyl protease deficiency is enhanced by conditions that impede intracellular acidification. We considered the contribution of additional cellular pH homeostasis mechanisms in necrosis. Two other major mechanisms have been implicat ...
... deficiency (Table I). We conclude that suppression of necrosis by aspartyl protease deficiency is enhanced by conditions that impede intracellular acidification. We considered the contribution of additional cellular pH homeostasis mechanisms in necrosis. Two other major mechanisms have been implicat ...
Lectin Labeling of Sprouting Neurons I. Regional Distribution of
... the number of ferritin particles per unit area of plasmalemma was measured in three different regions : perikaryon, neuritic shaft, and growth cone . Three different binding patterns are observed for different lectin : equal receptor density throughout the plasmalemma of the growing neuron (e .g ., ...
... the number of ferritin particles per unit area of plasmalemma was measured in three different regions : perikaryon, neuritic shaft, and growth cone . Three different binding patterns are observed for different lectin : equal receptor density throughout the plasmalemma of the growing neuron (e .g ., ...
Research
... The traditional paradigm encompassing the flow of information from gene to protein to function can be found in nearly every biology and biochemistry textbook. At the time, this discovery was thought to explain all of biology, health, and disease. However, only focusing on the expression of a single ...
... The traditional paradigm encompassing the flow of information from gene to protein to function can be found in nearly every biology and biochemistry textbook. At the time, this discovery was thought to explain all of biology, health, and disease. However, only focusing on the expression of a single ...
Ion channels in the immune system as targets for
... Signaling pathways in T-cell activation: the role of ion channels Ion channels underlie the Ca2+ signal of T cells [2]. Initially, phospholipase C-mobilized IP3 produces a transient [Ca2+]i rise by activating the IP3 receptor, a Ca2+-permeable ion channel located in the endoplasmic reticulum. IP3 re ...
... Signaling pathways in T-cell activation: the role of ion channels Ion channels underlie the Ca2+ signal of T cells [2]. Initially, phospholipase C-mobilized IP3 produces a transient [Ca2+]i rise by activating the IP3 receptor, a Ca2+-permeable ion channel located in the endoplasmic reticulum. IP3 re ...
the versatile bacterial type iv secretion systems
... Although it is clear that the CP coordinates with the Mpf complex to drive DNA transfer, until recently it was not known whether the CP physically interacts with the Mpf structure. Now, two studies have reported that CPs form stable interactions with homologues of the A. tumefaciens VirB10 protein35 ...
... Although it is clear that the CP coordinates with the Mpf complex to drive DNA transfer, until recently it was not known whether the CP physically interacts with the Mpf structure. Now, two studies have reported that CPs form stable interactions with homologues of the A. tumefaciens VirB10 protein35 ...
Genome Biology - Rodrigo A. Gutierrez Laboratory
... Integrating carbon (C) and nitrogen (N) metabolism is essential for the growth and development of living organisms. In addition to their essential roles as macronutrients, both C and N metabolites can act as signals that influence many cellular processes through regulation of gene expression in plan ...
... Integrating carbon (C) and nitrogen (N) metabolism is essential for the growth and development of living organisms. In addition to their essential roles as macronutrients, both C and N metabolites can act as signals that influence many cellular processes through regulation of gene expression in plan ...
The proteomics of plant cell membranes
... spectrometry on mono-dimensional gels, allowing the identification of about 100 proteins, 95% of which had never been found in previous proteomic studies. Alexandersson et al. (2004) used nano-flow reversed-phase chromatography coupled ‘on-line’ to an electrospray ionization mass spectrometer, and i ...
... spectrometry on mono-dimensional gels, allowing the identification of about 100 proteins, 95% of which had never been found in previous proteomic studies. Alexandersson et al. (2004) used nano-flow reversed-phase chromatography coupled ‘on-line’ to an electrospray ionization mass spectrometer, and i ...
Evolving Concepts in G Protein-Coupled Receptor Endocytosis: The
... II. G protein-coupled receptor desensitization . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 3 A. Protein kinase phosphorylation . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . ...
... II. G protein-coupled receptor desensitization . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 3 A. Protein kinase phosphorylation . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . ...
Planta
... development of post-harvest practices to enhance fruit quality. Proteomics is becoming a powerful tool in plant research in the last few years. The development of state-of-the-art LC-MS/MS technology, Wne separation techniques, development of genomic, and ESTs databases for a variety of species and ...
... development of post-harvest practices to enhance fruit quality. Proteomics is becoming a powerful tool in plant research in the last few years. The development of state-of-the-art LC-MS/MS technology, Wne separation techniques, development of genomic, and ESTs databases for a variety of species and ...
Cell abstracts - Society for Experimental Biology
... and others in the nuclear interior. These chromosome and gene positions do not vary much over the proliferative cell cycle since they are fixed in place, anchored by various nuclear structures including the nuclear lamina. However, upon a stimulus such as growth factor restriction, heat shock or par ...
... and others in the nuclear interior. These chromosome and gene positions do not vary much over the proliferative cell cycle since they are fixed in place, anchored by various nuclear structures including the nuclear lamina. However, upon a stimulus such as growth factor restriction, heat shock or par ...
Signal transduction
Signal transduction occurs when an extracellular signaling molecule activates a specific receptor located on the cell surface or inside the cell. In turn, this receptor triggers a biochemical chain of events inside the cell, creating a response. Depending on the cell, the response alters the cell's metabolism, shape, gene expression, or ability to divide. The signal can be amplified at any step. Thus, one signaling molecule can cause many responses.