Alternative translation initiation gives rise to two isoforms of Orai1
... channels are comprised of subunits of the recently discovered Orai proteins, the major one being Orai1.We have discovered that native Orai1, as well as expressed Orai1, exists in two forms in similar quantities: a longer form (Orai1a) of approximately 33 kDa, and a shorter form (Orai1b) of approxima ...
... channels are comprised of subunits of the recently discovered Orai proteins, the major one being Orai1.We have discovered that native Orai1, as well as expressed Orai1, exists in two forms in similar quantities: a longer form (Orai1a) of approximately 33 kDa, and a shorter form (Orai1b) of approxima ...
Photobleaching Substrates Characterized Using Fluorescence
... Despite the evidence that Ku functions in NHEJ during repair of DSBs, its properties in intact cells are unclear. For example, little is known concerning the dynamics of Ku in intact nuclei as defined by its mobility and the rate at which it associates with substrates. Interestingly, recent studies ...
... Despite the evidence that Ku functions in NHEJ during repair of DSBs, its properties in intact cells are unclear. For example, little is known concerning the dynamics of Ku in intact nuclei as defined by its mobility and the rate at which it associates with substrates. Interestingly, recent studies ...
Have you ever counted how long you could hold your breath for? In
... your breath for? In May 2007, a trained diver broke a world record. He held his breath underwater for 9 minutes and 8 seconds! Most people can't hold their breath for nearly that long. That's because the human body needs an almost constant supply of oxygen to live. And oxygen comes from the air you ...
... your breath for? In May 2007, a trained diver broke a world record. He held his breath underwater for 9 minutes and 8 seconds! Most people can't hold their breath for nearly that long. That's because the human body needs an almost constant supply of oxygen to live. And oxygen comes from the air you ...
Targeting Nitric Oxide Mediated Upregulation of Membrane
... are expressed on tumor cells but not on healthy tissue, and are surface exposed to be easily targeted by the therapeutic antibody. The mechanism by which antibodies bring about tumor cell death are often complex, but can include recruitment of effector elements (such as complement, or cell-mediated ...
... are expressed on tumor cells but not on healthy tissue, and are surface exposed to be easily targeted by the therapeutic antibody. The mechanism by which antibodies bring about tumor cell death are often complex, but can include recruitment of effector elements (such as complement, or cell-mediated ...
PPT - Hss-1.us
... Lysosomes: Lysosomes are organelles containing digestive enzymes (acid hydrolases). They are found in animal cells, while in plant cells the same roles are performed by the vacuole. They digest excess or worn-out organelles, food particles, and engulfed viruses or bacteria. The membrane surrounding ...
... Lysosomes: Lysosomes are organelles containing digestive enzymes (acid hydrolases). They are found in animal cells, while in plant cells the same roles are performed by the vacuole. They digest excess or worn-out organelles, food particles, and engulfed viruses or bacteria. The membrane surrounding ...
Chapter 14 Notes 2013
... Dermis: Is the thicker layer of the skin beneath the epidermis that is made up of connective tissue and contains blood vessels and nerves. The dermis has protein fibers that give the skin its elasticity, or spongy, flexible quality. Nerve cells in the dermis act as receptors, which are stimulate ...
... Dermis: Is the thicker layer of the skin beneath the epidermis that is made up of connective tissue and contains blood vessels and nerves. The dermis has protein fibers that give the skin its elasticity, or spongy, flexible quality. Nerve cells in the dermis act as receptors, which are stimulate ...
The morphologies of breast cancer cell lines in three
... classification: Round, Mass, Grape-like and Stellate. 3D cultures were stained for F-actin and nuclei were counterstained with DAPI. Optical sections of representative colonies are shown for all cell lines (bottom panel) with the exception of MDA-MB-468 for which a Z projection with maximum intensit ...
... classification: Round, Mass, Grape-like and Stellate. 3D cultures were stained for F-actin and nuclei were counterstained with DAPI. Optical sections of representative colonies are shown for all cell lines (bottom panel) with the exception of MDA-MB-468 for which a Z projection with maximum intensit ...
The Regulation of Glutaminolysis and Citric Acid Cycle Activity
... the essential generation of cellular energy and biomass from extracellular substrates. It constitutes the basis for cell growth, and understanding the dynamics in metabolic activity is fundamental for analysis and improvement of biotechnological processes involving mammalian cells, e.g. in vaccine ( ...
... the essential generation of cellular energy and biomass from extracellular substrates. It constitutes the basis for cell growth, and understanding the dynamics in metabolic activity is fundamental for analysis and improvement of biotechnological processes involving mammalian cells, e.g. in vaccine ( ...
Plant Growth - Biology Junction
... ethylene triggers ripening ripening stimulates more ethylene production ...
... ethylene triggers ripening ripening stimulates more ethylene production ...
Laboratory # 2 Observation of Microorganisms Purpose: The
... range microorganisms. Introduction: Definition of a Microorganism - a microscopic form of life that can only be studied under a microscope, including bacteria, viruses, fungi, algae, protozoa and some multicellular parasites. Divisions of Microorganisms - they can be divided into Eukaryotes and Prok ...
... range microorganisms. Introduction: Definition of a Microorganism - a microscopic form of life that can only be studied under a microscope, including bacteria, viruses, fungi, algae, protozoa and some multicellular parasites. Divisions of Microorganisms - they can be divided into Eukaryotes and Prok ...
Lecture Slides
... immune cells by forming holes in the plasma membrane. • Question: Does PSM play a role in MRSA infections? • Hypothesis: MRSA bacteria lacking the ability to produce PSM would be less deadly than normal MRSA strains. ...
... immune cells by forming holes in the plasma membrane. • Question: Does PSM play a role in MRSA infections? • Hypothesis: MRSA bacteria lacking the ability to produce PSM would be less deadly than normal MRSA strains. ...
Stem cells: the intestinal stem cell as a paradigm
... can be aimed. (ii) The rapidly dividing tissues of bone marrow, gut and skin are the first to be affected by cancer treatment. Toxicity in these tissues is dose limiting for many chemotherapeutic agents or radiotherapeutic practises. Isolation of viable stem cells could be used as a therapeutic mano ...
... can be aimed. (ii) The rapidly dividing tissues of bone marrow, gut and skin are the first to be affected by cancer treatment. Toxicity in these tissues is dose limiting for many chemotherapeutic agents or radiotherapeutic practises. Isolation of viable stem cells could be used as a therapeutic mano ...
Packet 18- Kidneys
... A. SGLT transporters… Na+ comes into the cell (down the conc gradient) and brings glucose with it! 5. On the basolateral membrane (touching the interstitial fluid): A. NaK Pump!!! (3 Na+ out, 2 K+ in…)…uses ATP B. Maintains the Na+ conc gradient C. (K+ leaks out of open channels, preventing too ...
... A. SGLT transporters… Na+ comes into the cell (down the conc gradient) and brings glucose with it! 5. On the basolateral membrane (touching the interstitial fluid): A. NaK Pump!!! (3 Na+ out, 2 K+ in…)…uses ATP B. Maintains the Na+ conc gradient C. (K+ leaks out of open channels, preventing too ...
The Relationship between Methylmercury Dosages and Amount of
... Once in the ICUC, the control slide was placed on a Nikon Eclipse E200 microscope stage. The microscope was aligned for Koehler illumination under transmitted light. Using the eyepieces, a bubble was brought into focus using a 10X objective. From there, the stage was dropped and the leve ...
... Once in the ICUC, the control slide was placed on a Nikon Eclipse E200 microscope stage. The microscope was aligned for Koehler illumination under transmitted light. Using the eyepieces, a bubble was brought into focus using a 10X objective. From there, the stage was dropped and the leve ...
How viruses damage cells: alterations in plasma
... situation: (i) during the toxin-like action of paramyxoviruses when fusing with susceptible cells, and (ii) during an infectious cycle initiated by different viruses in various cell types. The nature of the permeability changes induced during the toxin-like action of viruses, and its modulation by e ...
... situation: (i) during the toxin-like action of paramyxoviruses when fusing with susceptible cells, and (ii) during an infectious cycle initiated by different viruses in various cell types. The nature of the permeability changes induced during the toxin-like action of viruses, and its modulation by e ...
Infectious Diseases in Obstetrics and Gynecology Vol. 2008, Article
... [17]. Following these guidelines successfully treats 60% of BV cases, but 20% of these cases return with highly developed antibiotic resistances [18–20]. In such cases, it would be extremely desirable to have an alternative form of treatment that could fully eradicate the infection. ...
... [17]. Following these guidelines successfully treats 60% of BV cases, but 20% of these cases return with highly developed antibiotic resistances [18–20]. In such cases, it would be extremely desirable to have an alternative form of treatment that could fully eradicate the infection. ...
Cell Organelle PPT
... LIGHTLY sand each side of the plastic Choose either the plant or animal cell and trace it onto the plastic using permanent markers ...
... LIGHTLY sand each side of the plastic Choose either the plant or animal cell and trace it onto the plastic using permanent markers ...
Mislocalization and inhibition of acetyl
... twice with ice-cold PBS, collected and then extracted with M-PER mammalian protein extraction reagent (Thermo Scientific) in the presence of inhibitors for proteinases and phosphatases (Roche). ACC activity in the extracts was monitored as described previously [18]. Briefly, equal amounts of cell ex ...
... twice with ice-cold PBS, collected and then extracted with M-PER mammalian protein extraction reagent (Thermo Scientific) in the presence of inhibitors for proteinases and phosphatases (Roche). ACC activity in the extracts was monitored as described previously [18]. Briefly, equal amounts of cell ex ...
Host B7x Promotes Pulmonary Metastasis of Breast Cancer
... that can further grow into independent tumors, but this depends largely on interactions between these cells and their new environment (1). The immune system plays an important role in these processes. In addition to infiltration by effector immune cells attempting to mount antitumor responses, growi ...
... that can further grow into independent tumors, but this depends largely on interactions between these cells and their new environment (1). The immune system plays an important role in these processes. In addition to infiltration by effector immune cells attempting to mount antitumor responses, growi ...
the pathogenesis of sendai virus infection in the mouse lung twe
... within 24 hr of infection and had reached its peak by the 5th day. Since the cells of the bronchial mucous membrane were showing degenerative changes from the 1st day, it is reasonable to assume that the virus was replicating in these cells and that it was the replication of the virus that was respo ...
... within 24 hr of infection and had reached its peak by the 5th day. Since the cells of the bronchial mucous membrane were showing degenerative changes from the 1st day, it is reasonable to assume that the virus was replicating in these cells and that it was the replication of the virus that was respo ...
Medical Terminology Course
... transfer of an impulse, e.g. nerve cells. The all or none law. A stimulus to a nerve or muscle causes it to respond to its greatest extent or not at all. Impulses all travel at the same rate but nerves only respond to a threshold stimulus. 2.5 Water Approximately 66% of the body is water, which is c ...
... transfer of an impulse, e.g. nerve cells. The all or none law. A stimulus to a nerve or muscle causes it to respond to its greatest extent or not at all. Impulses all travel at the same rate but nerves only respond to a threshold stimulus. 2.5 Water Approximately 66% of the body is water, which is c ...
knockout, knock-in, and conditional mutant mice
... 2. A device suitable for electroporation of eukaryotic tissue culture cells--the models sold by BioRad are widely used in gene targeting labs. The current model is the Gene Pulser Xcell electroporation device, and requires the CE (capacitance extender) module for electroporation of ES cells. 3. G418 ...
... 2. A device suitable for electroporation of eukaryotic tissue culture cells--the models sold by BioRad are widely used in gene targeting labs. The current model is the Gene Pulser Xcell electroporation device, and requires the CE (capacitance extender) module for electroporation of ES cells. 3. G418 ...
ROLE OF B LYMPHOCYTES IN CELL
... Bone marrow-derived (B) lymphocytes are antibody-forming cell precursors which when appropriately activated differentiate into antibody-secreting cells. Activation of B lymphocytes by mitogens and certain thymic-independent antigens is thought to occur directly without cooperation of other cells (I, ...
... Bone marrow-derived (B) lymphocytes are antibody-forming cell precursors which when appropriately activated differentiate into antibody-secreting cells. Activation of B lymphocytes by mitogens and certain thymic-independent antigens is thought to occur directly without cooperation of other cells (I, ...
Tissue engineering
Tissue engineering is the use of a combination of cells, engineering and materials methods, and suitable biochemical and physicochemical factors to improve or replace biological functions. While it was once categorized as a sub-field of biomaterials, having grown in scope and importance it can be considered as a field in its own right.While most definitions of tissue engineering cover a broad range of applications, in practice the term is closely associated with applications that repair or replace portions of or whole tissues (i.e., bone, cartilage, blood vessels, bladder, skin, muscle etc.). Often, the tissues involved require certain mechanical and structural properties for proper functioning. The term has also been applied to efforts to perform specific biochemical functions using cells within an artificially-created support system (e.g. an artificial pancreas, or a bio artificial liver). The term regenerative medicine is often used synonymously with tissue engineering, although those involved in regenerative medicine place more emphasis on the use of stem cells or progenitor cells to produce tissues.