Inflammation near the Nerve Cell Body
... sensoryaxons (McQuarrie et al., 1977; Richardson and Verge, 1987). The present observations suggestthat similar reactions can be elicited by more direct stimulation of the nerve cell body. Injection into the DRG of either macrophagesor the inflammatory agent C. parvum significantly enhancesaxonal re ...
... sensoryaxons (McQuarrie et al., 1977; Richardson and Verge, 1987). The present observations suggestthat similar reactions can be elicited by more direct stimulation of the nerve cell body. Injection into the DRG of either macrophagesor the inflammatory agent C. parvum significantly enhancesaxonal re ...
Immunocytochemical Localization of the
... gene driving cell replication (4-6). In any case it is clear from studies done in tissue culture that the presence of adequate quantities of properly functioning intracellular glucocorticoid receptors is a necessary though not sufficient component for lymphocytolysis (7-9). These facts, plus the suc ...
... gene driving cell replication (4-6). In any case it is clear from studies done in tissue culture that the presence of adequate quantities of properly functioning intracellular glucocorticoid receptors is a necessary though not sufficient component for lymphocytolysis (7-9). These facts, plus the suc ...
mycoplasmas in tissue culture
... In many cultures found to be contaminated with mycoplasmas the changes in the cells have been minimal or inapparent (Rothblat, i960; Carski & Shepard, 1961; Kraemer et al., 1963) and may be insufficient to cause the worker to seek their replacement or even to suspect there is anything amiss. Even he ...
... In many cultures found to be contaminated with mycoplasmas the changes in the cells have been minimal or inapparent (Rothblat, i960; Carski & Shepard, 1961; Kraemer et al., 1963) and may be insufficient to cause the worker to seek their replacement or even to suspect there is anything amiss. Even he ...
Cells Cell Stimulatory Capacity to Mouse Dendritic Associated with
... microbial infection. It is present and conserved in all animals throughout evolution (1). Among the cells that are involved in innate responses, dendritic cells (DCs)3 are able to perceive the environment and to alert the innate immune system to the presence of invading microorganisms. During the ve ...
... microbial infection. It is present and conserved in all animals throughout evolution (1). Among the cells that are involved in innate responses, dendritic cells (DCs)3 are able to perceive the environment and to alert the innate immune system to the presence of invading microorganisms. During the ve ...
Part-5-Inflammatory-diseases-processes-and
... systemic inflammation, such as obesity, diabetes, inflammatory bowel disease, rheumatoid arthritis, and osteoarthritis, vascular diseases and even cancer and Alzheimer’s disease. Lifestyle-related diseases are becoming more synonymous with chronic systemic inflammation because of an imbalance of the ...
... systemic inflammation, such as obesity, diabetes, inflammatory bowel disease, rheumatoid arthritis, and osteoarthritis, vascular diseases and even cancer and Alzheimer’s disease. Lifestyle-related diseases are becoming more synonymous with chronic systemic inflammation because of an imbalance of the ...
Full Text - Digital Access to Scholarship at Harvard
... detail. Our results revealed that several molecules such as Foxp3 and CD39/CD73 are shared by both, Treg and melanoma cells and that those Treg specific marker molecules are highly expressed on different melanoma cell lines compared to normal melanocytes. Surprisingly, we also detected GARP on the m ...
... detail. Our results revealed that several molecules such as Foxp3 and CD39/CD73 are shared by both, Treg and melanoma cells and that those Treg specific marker molecules are highly expressed on different melanoma cell lines compared to normal melanocytes. Surprisingly, we also detected GARP on the m ...
Listeria In Vivo Dynamic Imaging of the Effector Immune Response to Infection
... has provided high-resolution information on the dynamic interactions that take place during immune responses in situ. Tracking of cells in real time reveals kinetic information that is lacking from static images. Intravital microscopy has been useful in understanding tissue specific responses to pat ...
... has provided high-resolution information on the dynamic interactions that take place during immune responses in situ. Tracking of cells in real time reveals kinetic information that is lacking from static images. Intravital microscopy has been useful in understanding tissue specific responses to pat ...
A balanced pyrimidine pool is required for optimal Chk1 activation to
... reflect a defect in sister chromatid segregation during anaphase. They cannot be stained with conventional DNA dyes or antibodies against histones, but they can be detected with an antibody against Plk1-interacting checkpoint helicase (PICH, also known as ERCC6L), a protein recruited to UFBs (Bauman ...
... reflect a defect in sister chromatid segregation during anaphase. They cannot be stained with conventional DNA dyes or antibodies against histones, but they can be detected with an antibody against Plk1-interacting checkpoint helicase (PICH, also known as ERCC6L), a protein recruited to UFBs (Bauman ...
HueyLing - Principles of Bioseparations.pmd
... conditions such as pH and ionic strengths, hydrodynamic conditions such as high shear rates, and exposure to gas-liquid interfaces. Organic solvents which are widely used in chemical separations have relatively limited usage in bioseparations on account of their tendency to promote degradation of ma ...
... conditions such as pH and ionic strengths, hydrodynamic conditions such as high shear rates, and exposure to gas-liquid interfaces. Organic solvents which are widely used in chemical separations have relatively limited usage in bioseparations on account of their tendency to promote degradation of ma ...
Cdk1 regulates centrosome separation by restraining proteolysis of
... exhibits synthetic lethal interaction with another microtubule-associated protein Ase1 (Schuyler et al, 2003). We have observed spindle formation defects in cin8D ase1D, suggesting a possible role for Ase1 in spindle assembly (data not shown). It is possible that failure to separate SPBs in cdc28Y19 ...
... exhibits synthetic lethal interaction with another microtubule-associated protein Ase1 (Schuyler et al, 2003). We have observed spindle formation defects in cin8D ase1D, suggesting a possible role for Ase1 in spindle assembly (data not shown). It is possible that failure to separate SPBs in cdc28Y19 ...
Electrophysiological properties of mouse bone marrow c
... currents (I Kir), which are physiologically designed to set membrane resting potential [17]. The relationship between current density and test potentials (Fig. 3B) shows that rectification was incomplete, with a small current evoked at 0 mV, even in cells lacking an outward K+ current. Cs+ is a well ...
... currents (I Kir), which are physiologically designed to set membrane resting potential [17]. The relationship between current density and test potentials (Fig. 3B) shows that rectification was incomplete, with a small current evoked at 0 mV, even in cells lacking an outward K+ current. Cs+ is a well ...
Flamingo regulates epiboly and convergence/extension movements
... During vertebrate gastrulation, the body axis is established by coordinated and directional movements of cells that include epiboly, involution, and convergence and extension (C&E). Recent work implicates a non-canonical Wnt/planar cell polarity (PCP) pathway in the regulation of C&E. The Drosophila ...
... During vertebrate gastrulation, the body axis is established by coordinated and directional movements of cells that include epiboly, involution, and convergence and extension (C&E). Recent work implicates a non-canonical Wnt/planar cell polarity (PCP) pathway in the regulation of C&E. The Drosophila ...
Cell Transport and Homeostasis PowerPoint
... Other junctions allow small molecules carrying chemical messages to pass directly from one cell to the next. To respond to one of these chemical signals, a cell must have a receptor to which the signaling molecule can bind. Sometimes these receptors are on the cell membrane, although the receptors f ...
... Other junctions allow small molecules carrying chemical messages to pass directly from one cell to the next. To respond to one of these chemical signals, a cell must have a receptor to which the signaling molecule can bind. Sometimes these receptors are on the cell membrane, although the receptors f ...
Regulation of Potassium Transport in Leaves: from Molecular to
... regulation (Marten et al., 1999). Being only weakly controlled by the membrane potential, AKT2/3 channels are able to conduct both inward and outward currents. Electrophysiologically, K+-permeable channels at the plasma membrane of mesophyll cells were characterized as KIRs (Kourie and Goldsmith, 19 ...
... regulation (Marten et al., 1999). Being only weakly controlled by the membrane potential, AKT2/3 channels are able to conduct both inward and outward currents. Electrophysiologically, K+-permeable channels at the plasma membrane of mesophyll cells were characterized as KIRs (Kourie and Goldsmith, 19 ...
PDF
... Despite the clear advantages of using Drosophila in cell-plasticity studies, the cellular mechanisms driving the recovery of normal organ size and shape are still poorly understood. Two different scenarios can be predicted for disc regeneration. The first considers that regeneration involves a gener ...
... Despite the clear advantages of using Drosophila in cell-plasticity studies, the cellular mechanisms driving the recovery of normal organ size and shape are still poorly understood. Two different scenarios can be predicted for disc regeneration. The first considers that regeneration involves a gener ...
Anthraquinone emodin inhibits human cancer
... and apoptosis, thereby contributing to modulation of several physiological processes. ATP has been found at relatively high concentrations in the tumor microenvironments (4) where it is released from living cancer cells (5) and also from necrotic cells in the perilesional regions of cancers (6), rai ...
... and apoptosis, thereby contributing to modulation of several physiological processes. ATP has been found at relatively high concentrations in the tumor microenvironments (4) where it is released from living cancer cells (5) and also from necrotic cells in the perilesional regions of cancers (6), rai ...
Mitosis in the Mouse: A Study of Living and
... tissue culture by W. H. Lewis (1940). This author, however, does not distinguish between the Feulgen-positive chromocentres and the Feulgennegative nucleoli and applies the latter term to all intranuclear granules. It seems clear, however, that the 'small nucleoli' of Lewis which were seen to be in ...
... tissue culture by W. H. Lewis (1940). This author, however, does not distinguish between the Feulgen-positive chromocentres and the Feulgennegative nucleoli and applies the latter term to all intranuclear granules. It seems clear, however, that the 'small nucleoli' of Lewis which were seen to be in ...
L2 Inflam 20162016-10-24 22:226.6 MB
... 4. Mucin-like glycoproteins: PECAM-1 - these glycoproteins are found in the extracellular matrix and on cell surfaces. ...
... 4. Mucin-like glycoproteins: PECAM-1 - these glycoproteins are found in the extracellular matrix and on cell surfaces. ...
Adducin-1 is essential for mitotic spindle assembly through its
... chromosomes in mitotic cells (Fig. 5 C and Videos 1–5). This aberrance can be classified into three types (Fig. 5 D). In type I, chromosomes undergo incomplete congression and then proceed to segregation, which leads to micronuclei in daughter cells (Video 3). In type II, chromosomes proceed to segr ...
... chromosomes in mitotic cells (Fig. 5 C and Videos 1–5). This aberrance can be classified into three types (Fig. 5 D). In type I, chromosomes undergo incomplete congression and then proceed to segregation, which leads to micronuclei in daughter cells (Video 3). In type II, chromosomes proceed to segr ...
Stochastic Responses May Allow Genetically Diverse Cell
... noise was suppressed (e.g., with more molecules). The same conclusion holds even if the expected costs are not strictly increasing (decreasing), as long as they do not intersect more than once. Why do T cells not suppress this ‘‘noise’’?. T cells are coupled at the population level. T cells, like ot ...
... noise was suppressed (e.g., with more molecules). The same conclusion holds even if the expected costs are not strictly increasing (decreasing), as long as they do not intersect more than once. Why do T cells not suppress this ‘‘noise’’?. T cells are coupled at the population level. T cells, like ot ...
Research Project Final Report
... The primary aim of this project was to identify cell lines directly permissive to ovine scrapie by further investigation of existing cell lines with proven ability to propagate sheep scrapie, through the development and characterisation of further Rov lines expressing natural ovine PrP alleles and n ...
... The primary aim of this project was to identify cell lines directly permissive to ovine scrapie by further investigation of existing cell lines with proven ability to propagate sheep scrapie, through the development and characterisation of further Rov lines expressing natural ovine PrP alleles and n ...
The fission yeast Schizosaccharomyces pombe has two
... There are multiple importin-α proteins in metazoan organisms and they have been categorized based on amino-acid sequence comparisons (MALIK et al. 1997; MASON et al. 2002). Three sub-families, whose members have different expression patterns, different functions, and/or different cargo binding spec ...
... There are multiple importin-α proteins in metazoan organisms and they have been categorized based on amino-acid sequence comparisons (MALIK et al. 1997; MASON et al. 2002). Three sub-families, whose members have different expression patterns, different functions, and/or different cargo binding spec ...
Identification and Characterization of Genes Required for
... Abigail R. Gerhold, Daniel J. Richter, Albert S. Yu, and Iswar K. Hariharan1 Department of Molecular and Cell Biology, University of California, Berkeley, California 94720-3200 ...
... Abigail R. Gerhold, Daniel J. Richter, Albert S. Yu, and Iswar K. Hariharan1 Department of Molecular and Cell Biology, University of California, Berkeley, California 94720-3200 ...
Abstract Infection of plants by Zucchini Yellow Mosaic Virus (ZYMV
... as pinwheels, bundles, scrolls, and short usually curved laminated aggregates (Edwardson, 1992 and Edwardson and Christie, 1996). Even though their two dimensional (2D) ultrastructure has been described in detail, the three dimensional (3D) fine structure remains unclear. Additionally, it was unclea ...
... as pinwheels, bundles, scrolls, and short usually curved laminated aggregates (Edwardson, 1992 and Edwardson and Christie, 1996). Even though their two dimensional (2D) ultrastructure has been described in detail, the three dimensional (3D) fine structure remains unclear. Additionally, it was unclea ...
7-1 Life Is Cellular
... plants were made of cells. In 1839, Theodor Schwann stated that all animals were made of cells. In 1855, Rudolph Virchow concluded that new cells were created only from the reproduction of existing cells. These discoveries led to the cell theory. Slide 7 of 31 Copyright Pearson Prentice Hall ...
... plants were made of cells. In 1839, Theodor Schwann stated that all animals were made of cells. In 1855, Rudolph Virchow concluded that new cells were created only from the reproduction of existing cells. These discoveries led to the cell theory. Slide 7 of 31 Copyright Pearson Prentice Hall ...
Tissue engineering
Tissue engineering is the use of a combination of cells, engineering and materials methods, and suitable biochemical and physicochemical factors to improve or replace biological functions. While it was once categorized as a sub-field of biomaterials, having grown in scope and importance it can be considered as a field in its own right.While most definitions of tissue engineering cover a broad range of applications, in practice the term is closely associated with applications that repair or replace portions of or whole tissues (i.e., bone, cartilage, blood vessels, bladder, skin, muscle etc.). Often, the tissues involved require certain mechanical and structural properties for proper functioning. The term has also been applied to efforts to perform specific biochemical functions using cells within an artificially-created support system (e.g. an artificial pancreas, or a bio artificial liver). The term regenerative medicine is often used synonymously with tissue engineering, although those involved in regenerative medicine place more emphasis on the use of stem cells or progenitor cells to produce tissues.