Polarity Control of Spindle Positioning in the C. elegans Embryo
... balance between symmetric and asymmetric division of stem cells and tissuespecific progenitor cells. How cell polarity information is translated into proper spindle positioning has been a subject of intense study over the past 15 years. Information from a variety of systems has resulted in a general ...
... balance between symmetric and asymmetric division of stem cells and tissuespecific progenitor cells. How cell polarity information is translated into proper spindle positioning has been a subject of intense study over the past 15 years. Information from a variety of systems has resulted in a general ...
Lecture2
... cellular division in the embryo without increase in the cytoplasm. Series of cleavage or division usually takes place in uterus and shell gland until 256 cell stage is reached, then there will be Gastrulation. Gastrulation is the movement of cells within the embryo to form the area of specific organ ...
... cellular division in the embryo without increase in the cytoplasm. Series of cleavage or division usually takes place in uterus and shell gland until 256 cell stage is reached, then there will be Gastrulation. Gastrulation is the movement of cells within the embryo to form the area of specific organ ...
Development
... by microprojectile bombardment. O-acetyl chitin oligosaccharides were enzymatically synthesised using R. leguminosarum bv. viciae NodL, which acetylates chitin oligosaccharides at the non-reducing C6 position (Bloemberg et al., 1994) (results not shown). Uridine (1×10−7 M or 5×10−7 M in the gold par ...
... by microprojectile bombardment. O-acetyl chitin oligosaccharides were enzymatically synthesised using R. leguminosarum bv. viciae NodL, which acetylates chitin oligosaccharides at the non-reducing C6 position (Bloemberg et al., 1994) (results not shown). Uridine (1×10−7 M or 5×10−7 M in the gold par ...
Regulated adhesion as a driving force of gastrulation movements
... relative positions within the germ layers to form and shape the body axis. Here, we argue that, with respect to their dependence on regulated cell adhesion, all types of gastrulation movement share certain crucial features, and are much more similar than was initially acknowledged. Cell adhesion des ...
... relative positions within the germ layers to form and shape the body axis. Here, we argue that, with respect to their dependence on regulated cell adhesion, all types of gastrulation movement share certain crucial features, and are much more similar than was initially acknowledged. Cell adhesion des ...
Role of the ABC Transporter Ste6 in Cell Fusion during Yeast
... well-mimicked by treatment with pheromones, the final degradation of the cell wall and membrane fusion of mating that leads to cytoplasmic mixing may require separate signals. Mutations that blocked cell fusion during mating in Saccharomyces cerevisiae were identified in a multipartite screen. The t ...
... well-mimicked by treatment with pheromones, the final degradation of the cell wall and membrane fusion of mating that leads to cytoplasmic mixing may require separate signals. Mutations that blocked cell fusion during mating in Saccharomyces cerevisiae were identified in a multipartite screen. The t ...
Title of the Project Cellular and molecular mechanisms of ozone
... Sequencing (NGS). In particular, the use of technologies for high-throughput sequencing of the transcriptome will provide an innovative approach to clarify the molecular pathways accounting for the action mechanisms of ozone identifying new markers that could represent targets for ozone therapy. Eve ...
... Sequencing (NGS). In particular, the use of technologies for high-throughput sequencing of the transcriptome will provide an innovative approach to clarify the molecular pathways accounting for the action mechanisms of ozone identifying new markers that could represent targets for ozone therapy. Eve ...
Functional diversification of centrins and cell morphological
... PtCenBP1p has previously been characterised as an essential component of the ICL forming the backbone of the network (Gogendeau et al., 2007). The new PtCenBP3 subfamily identified by the proteomic analysis comprises two proteins, PtCenBP2p and PtCenBP3p, which are paralogues of the most recent whol ...
... PtCenBP1p has previously been characterised as an essential component of the ICL forming the backbone of the network (Gogendeau et al., 2007). The new PtCenBP3 subfamily identified by the proteomic analysis comprises two proteins, PtCenBP2p and PtCenBP3p, which are paralogues of the most recent whol ...
... mRNA was not localized to the bud tip, it often appeared to form filamentous tracks extending from daughter cells into mother cells. In contrast to ASH1 mRNA, polyadenylated [poly(A)1] RNA was dispersed throughout both mother and daughter cells (Fig. 1A, top row). A null mutant of ASH1 that had been ...
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... events are hidden from view within complex tissues. Discovering their mechanism is a major opportunity and challenge in establishing the cellular basis of morphogenesis. Thus we developed the ‘open-faced’ explant system (Keller et al., 1985a,b), in which the dorsal marginal zone (DMZ) of the Xenopus ...
... events are hidden from view within complex tissues. Discovering their mechanism is a major opportunity and challenge in establishing the cellular basis of morphogenesis. Thus we developed the ‘open-faced’ explant system (Keller et al., 1985a,b), in which the dorsal marginal zone (DMZ) of the Xenopus ...
Two classic cadherin-related molecules with no cadherin
... The V-form cadherin genes are classified into type I and type II on the basis of phylogenetic differences (Takeichi, 1995). The type I cadherins are expressed rather ubiquitously, whereas the type II cadherins are expressed in more restricted cell populations. The major vertebrate type I cadherins a ...
... The V-form cadherin genes are classified into type I and type II on the basis of phylogenetic differences (Takeichi, 1995). The type I cadherins are expressed rather ubiquitously, whereas the type II cadherins are expressed in more restricted cell populations. The major vertebrate type I cadherins a ...
Is Evolutionary Theory Central to Molecular Cell Biology?
... phosporylate STAT proteins. STAT proteins that are so activated then accumulate in the nucleus and initiate transcription, ultimately affecting the phenotype of the cell. Particularly well studied are the Janus kinases (JAKs) and their STAT targets. The canonical Jak-Stat pathway is an important exa ...
... phosporylate STAT proteins. STAT proteins that are so activated then accumulate in the nucleus and initiate transcription, ultimately affecting the phenotype of the cell. Particularly well studied are the Janus kinases (JAKs) and their STAT targets. The canonical Jak-Stat pathway is an important exa ...
Pattern of Mutations that Results in Loss of Reduced Folate Carrier
... In four lines, two mutated RFC1 alleles with different frequencies were isolated. In one case, two mutations were found in the same allele, Met120Ile and Arg353Cys, in D19 cells. Six mutations were found in more than one cell line. Pro68Ser was identified three times in different cell lines, and Gly ...
... In four lines, two mutated RFC1 alleles with different frequencies were isolated. In one case, two mutations were found in the same allele, Met120Ile and Arg353Cys, in D19 cells. Six mutations were found in more than one cell line. Pro68Ser was identified three times in different cell lines, and Gly ...
Two-step process for photoreceptor formation inDrosophila
... R4 cells in most cases (not shown), we favour the transformation of `mystery cells' toward outer photoreceptor cell fate12. Finally, in a few cases, six or less PRCs were present. This could be accounted for by photoreceptor loss: older ¯ies exhibited dramatic pathology of some PRCs reminiscent of d ...
... R4 cells in most cases (not shown), we favour the transformation of `mystery cells' toward outer photoreceptor cell fate12. Finally, in a few cases, six or less PRCs were present. This could be accounted for by photoreceptor loss: older ¯ies exhibited dramatic pathology of some PRCs reminiscent of d ...
Boya
... appearance. If well-defined clumps of cocci are present in a clinical specimen and are extracellular, the identification of these organisms as staphylococci is ...
... appearance. If well-defined clumps of cocci are present in a clinical specimen and are extracellular, the identification of these organisms as staphylococci is ...
Towards a Small Emittance Design of the JLEIC Electron Collider Ring
... enhances the energy spread of the stored electron beam by a factor of 2.2. This demands more effort to obtain a large momentum acceptance and a higher RF peak voltage for keeping the same bunch length. In addition, damping wigglers radiate more power. The total synchrotron radiation power in the JLE ...
... enhances the energy spread of the stored electron beam by a factor of 2.2. This demands more effort to obtain a large momentum acceptance and a higher RF peak voltage for keeping the same bunch length. In addition, damping wigglers radiate more power. The total synchrotron radiation power in the JLE ...
Shininger, AnnRev. Plant Physiol. 1979 30:313-37
... of the leaf primordia,in fact, causesdisruption of this initially continuousprocambium, resulting in the formationof parenchymatous leaf gapsin the stem. Surgical removalof the primordiaresulted in eliminationof gapformation(I 39). ThusWardlaw believes that the cells abovethe leaf primordiarepresent ...
... of the leaf primordia,in fact, causesdisruption of this initially continuousprocambium, resulting in the formationof parenchymatous leaf gapsin the stem. Surgical removalof the primordiaresulted in eliminationof gapformation(I 39). ThusWardlaw believes that the cells abovethe leaf primordiarepresent ...
... tips were continuous and relatively straight (Figure 1a). On the contrary, in B-deficient plants the xylem vessels were tortuous and there were discontinuities. The same was true for the main and secondary veins of the leaves (Figures 2, 3). The vascular bundles in B deficient leaf veins were ...
REVIEW ARTICLE Mechanisms of pattern formation in development
... A key aspect of our treatment is the introduction (or rather appropriation) of the term ‘morphodynamic’ (distinguished from ‘morphostatic’) to characterize complex developmental mechanisms in which inductive and morphogenetic mechanisms interact with one another in a reciprocal fashion. The need for ...
... A key aspect of our treatment is the introduction (or rather appropriation) of the term ‘morphodynamic’ (distinguished from ‘morphostatic’) to characterize complex developmental mechanisms in which inductive and morphogenetic mechanisms interact with one another in a reciprocal fashion. The need for ...
Hyaluronidase enhances the activity of Adriamycin in breast cancer
... metastatic cancer or large local tumours (myeloma, melanoma, sarcoma, cancer of the pancreas, stomach, colon, lung - small cell and non-small cell, prostate, ovary and breast). Within each type of cancer individual patients showed strongly elevated levels of hyaluronic acid, but statistically signif ...
... metastatic cancer or large local tumours (myeloma, melanoma, sarcoma, cancer of the pancreas, stomach, colon, lung - small cell and non-small cell, prostate, ovary and breast). Within each type of cancer individual patients showed strongly elevated levels of hyaluronic acid, but statistically signif ...
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... occurred in the presence of all agents used, though it was modified by some of them. The results are discussed in terms of the molecular and cellular events underlying polarization, intercellular apposition and tight junction formation as well as the significance of these events for normal blastocys ...
... occurred in the presence of all agents used, though it was modified by some of them. The results are discussed in terms of the molecular and cellular events underlying polarization, intercellular apposition and tight junction formation as well as the significance of these events for normal blastocys ...
Surface Charge Distribution on the Endothelial Cell of Liver Sinusoids
... coated vesicles and in some small uncoated vesicles (-200nm-diam). The coated pits bound NF as distinct particles in single rows at a relatively large distance (20-30 nm) from the outer layer of the plasma membrane (Fig. 2 a). All the coated pits existing at a given time on the plasma membrane were ...
... coated vesicles and in some small uncoated vesicles (-200nm-diam). The coated pits bound NF as distinct particles in single rows at a relatively large distance (20-30 nm) from the outer layer of the plasma membrane (Fig. 2 a). All the coated pits existing at a given time on the plasma membrane were ...
Exocytosis and cell polarity in plants exocyst and recycling domains
... In metazoans, vesiculation of the whole Golgi complex takes place during mitosis; it can also be induced by ilimaquinone (Bard & Malhotra, 2006). This process, as well as TPC formation, requires trimeric G-proteins and a serine/threonine protein kinase D (PKD) interacting with DAG membrane domains ( ...
... In metazoans, vesiculation of the whole Golgi complex takes place during mitosis; it can also be induced by ilimaquinone (Bard & Malhotra, 2006). This process, as well as TPC formation, requires trimeric G-proteins and a serine/threonine protein kinase D (PKD) interacting with DAG membrane domains ( ...
Cell cycle
The cell cycle or cell-division cycle is the series of events that take place in a cell leading to its division and duplication (replication) that produces two daughter cells. In prokaryotes which lack a cell nucleus, the cell cycle occurs via a process termed binary fission. In cells with a nucleus, as in eukaryotes, the cell cycle can be divided into three periods: interphase, the mitotic (M) phase, and cytokinesis. During interphase, the cell grows, accumulating nutrients needed for mitosis, preparing it for cell division and duplicating its DNA. During the mitotic phase, the cell splits itself into two distinct daughter cells. During the final stage, cytokinesis, the new cell is completely divided. To ensure the proper division of the cell, there are control mechanisms known as cell cycle checkpoints.The cell-division cycle is a vital process by which a single-celled fertilized egg develops into a mature organism, as well as the process by which hair, skin, blood cells, and some internal organs are renewed. After cell division, each of the daughter cells begin the interphase of a new cycle. Although the various stages of interphase are not usually morphologically distinguishable, each phase of the cell cycle has a distinct set of specialized biochemical processes that prepare the cell for initiation of cell division.