Discreteness of chromosome territories
... spreads before fusion showed that all chromosomes were uniformly labeled (Fig. 2). Mitotic cells containing IdUrdDNA were fused with mitotic cells containing CldUrd-DNA. The cells were fixed 7 hours later when they had proceeded into the next interphase. Fused nuclei displayed a mosaic pattern of do ...
... spreads before fusion showed that all chromosomes were uniformly labeled (Fig. 2). Mitotic cells containing IdUrdDNA were fused with mitotic cells containing CldUrd-DNA. The cells were fixed 7 hours later when they had proceeded into the next interphase. Fused nuclei displayed a mosaic pattern of do ...
Muscle Cells - Circulation Research
... PCNA.8 The human PCNA gene is 4,961 base pairs long, has six exons, and localizes to chromosome 20.9,10 PCNA expression is regulated transcriptionally but has an important posttranscriptional component as well. Of interest is the fact that at least part of the transcriptional regulation appears to b ...
... PCNA.8 The human PCNA gene is 4,961 base pairs long, has six exons, and localizes to chromosome 20.9,10 PCNA expression is regulated transcriptionally but has an important posttranscriptional component as well. Of interest is the fact that at least part of the transcriptional regulation appears to b ...
Ribosome biogenesis and cell growth: mTOR coordinates
... pathway regulates the synthesis of ribosomal components, including transcription and processing of pre-rRNA, expression of ribosomal proteins and the synthesis of 5S rRNA. Expression of the genes encoding the numerous constituents of ribosomes requires transcription by all three classes of nuclear R ...
... pathway regulates the synthesis of ribosomal components, including transcription and processing of pre-rRNA, expression of ribosomal proteins and the synthesis of 5S rRNA. Expression of the genes encoding the numerous constituents of ribosomes requires transcription by all three classes of nuclear R ...
jxb.oxfordjournals.org
... cells (Folkers et al., 2002; Kim et al., 2002). AN3, which encodes a putative coactivator for the Arabidopsis growthregulating factor (AtGRF) family of transcription factors (J. H. Kim et al., 2003), also called AtGIF1 (GRFinteracting factor1), predominantly controls cell number in the leaf width di ...
... cells (Folkers et al., 2002; Kim et al., 2002). AN3, which encodes a putative coactivator for the Arabidopsis growthregulating factor (AtGRF) family of transcription factors (J. H. Kim et al., 2003), also called AtGIF1 (GRFinteracting factor1), predominantly controls cell number in the leaf width di ...
Commentary on “Research on Mitotic Mechanisms”
... components of the mitotic spindle. This note is a short account an open-access book chapter that charts stages in the growth of our understanding of mitotic mechanism, beginning with the discovery of the process and running up to about 1990 [1]. Most of the other chapters of the book [2] provide a t ...
... components of the mitotic spindle. This note is a short account an open-access book chapter that charts stages in the growth of our understanding of mitotic mechanism, beginning with the discovery of the process and running up to about 1990 [1]. Most of the other chapters of the book [2] provide a t ...
Supplementary Methods
... methylated (30 of 30 CpG sites methylated) controls, denoted UNMETH + and METH +, respectively. Agarose gel indicates equal loading of p15 amplicons for TTGE analysis. (dH2O) was a negative control with no PCR template. (b) TTGE analysis of p15 demethylation at varying doses of 5-Aza-dC (0 – 8 M). ...
... methylated (30 of 30 CpG sites methylated) controls, denoted UNMETH + and METH +, respectively. Agarose gel indicates equal loading of p15 amplicons for TTGE analysis. (dH2O) was a negative control with no PCR template. (b) TTGE analysis of p15 demethylation at varying doses of 5-Aza-dC (0 – 8 M). ...
How Have Plant Cell Walls Evolved?1
... XXXG XyG type in hornworts and tracheophytes is further evidence of a sister relationship between these groups (Peña et al., 2008). Even when cell wall analysis is narrowed down within a single plant group, there are often considerable variations in cell wall composition and/or cell wall architectu ...
... XXXG XyG type in hornworts and tracheophytes is further evidence of a sister relationship between these groups (Peña et al., 2008). Even when cell wall analysis is narrowed down within a single plant group, there are often considerable variations in cell wall composition and/or cell wall architectu ...
Crosstalk between Notch signaling Pathway and Glutamine uptake
... CD4+ T cells along with simultaneous activation of Notch1 signaling pathway prevented IL2 and INFγ production while inhibiting presenilin enhanced the T cell proliferation upon stimulation (Eagar, T. N. 2004[18] ) . On the other hand stimulation of Notch3 by Delta1 ligand during activation of CD4+ c ...
... CD4+ T cells along with simultaneous activation of Notch1 signaling pathway prevented IL2 and INFγ production while inhibiting presenilin enhanced the T cell proliferation upon stimulation (Eagar, T. N. 2004[18] ) . On the other hand stimulation of Notch3 by Delta1 ligand during activation of CD4+ c ...
DNA Damage Response in Plants: Conserved and Variable
... Interestingly, no plant homologs of p53 have been identified in any of the model plants, which is likely linked to the absence of the core apoptotic machinery in plants [67]. This observation raises the question of whether plants have a factor that has similar function with p53. An answer to this ca ...
... Interestingly, no plant homologs of p53 have been identified in any of the model plants, which is likely linked to the absence of the core apoptotic machinery in plants [67]. This observation raises the question of whether plants have a factor that has similar function with p53. An answer to this ca ...
A novel microtubule-modulating noscapinoid
... P Karna1, PCG Rida2, V Pannu1, KK Gupta3, WB Dalton4, H Joshi2, VW Yang4, J Zhou5 and R Aneja*,1 ...
... P Karna1, PCG Rida2, V Pannu1, KK Gupta3, WB Dalton4, H Joshi2, VW Yang4, J Zhou5 and R Aneja*,1 ...
Introduction 1.1 The Importance of Homeostasis in Maintaining
... and survival. Yeast requires substrates and enzymes for cell function, and these are found in aqueous solution (Walker, 1998). Without high water concentrations, enzymatic activity would cease and therefore impair normal cell function. Different yeast strains exhibit different tolerance levels to ch ...
... and survival. Yeast requires substrates and enzymes for cell function, and these are found in aqueous solution (Walker, 1998). Without high water concentrations, enzymatic activity would cease and therefore impair normal cell function. Different yeast strains exhibit different tolerance levels to ch ...
The Regulation of S Phase Initiation by p27Kip1 in NIH3T3 Cells
... cyclin D1 levels are normally induced,1 while p27Kip1 (p27) levels are suppressed.2 These two molecular events then directly influence the activity of key cell cycle regulatory proteins. Cyclin D1 associated with cyclin dependent kinase (CDK) 4 or 6 inactivates the growth inhibitory retinoblastoma p ...
... cyclin D1 levels are normally induced,1 while p27Kip1 (p27) levels are suppressed.2 These two molecular events then directly influence the activity of key cell cycle regulatory proteins. Cyclin D1 associated with cyclin dependent kinase (CDK) 4 or 6 inactivates the growth inhibitory retinoblastoma p ...
Collagenase - Thermo Fisher Scientific
... disaggregation. Collagenase is a protease with specificity for the bond between a neutral amino acid (X) and glycine in the sequence Pro-XGly-Pro. This sequence is found in high frequency in collagen. Collagenase is unique among proteases in its ability to degrade the triplehelical native collagen f ...
... disaggregation. Collagenase is a protease with specificity for the bond between a neutral amino acid (X) and glycine in the sequence Pro-XGly-Pro. This sequence is found in high frequency in collagen. Collagenase is unique among proteases in its ability to degrade the triplehelical native collagen f ...
PDF
... The Chlorophyceae are the largest group of green algae and exhibit great morphological diversity ranging from motile unicells to large filaments to blade-like thalli. The extracellular coverings of the Chlorophycean algae are also very diverse and consist of a distinct assortment of “cell walls.” In ...
... The Chlorophyceae are the largest group of green algae and exhibit great morphological diversity ranging from motile unicells to large filaments to blade-like thalli. The extracellular coverings of the Chlorophycean algae are also very diverse and consist of a distinct assortment of “cell walls.” In ...
Importance of T-Cell Receptor -Chain Gene Analysis
... lymphoma. They had rearrangement in DDJ(5/6) or VDJ(1/6) of TCR d locus.8 All patients achieved a complete remission. It is of interest that all but 1 had relapsed with a transformation to the mixed phenotype (triphenotype in 3 patients, biphenotype in 2), including myeloid features in 3 patients. T ...
... lymphoma. They had rearrangement in DDJ(5/6) or VDJ(1/6) of TCR d locus.8 All patients achieved a complete remission. It is of interest that all but 1 had relapsed with a transformation to the mixed phenotype (triphenotype in 3 patients, biphenotype in 2), including myeloid features in 3 patients. T ...
The in vitro development of blastocyst
... Rizzino, 1983). Few EC cell lines are capable of spontaneous differentiation, and of these very few have the capacity to form cystic structures with phenotypic similarities to the postimplantation embryo (Rosenthal et al. 1970; Martin, Wiley & Damjanov, 1977; Cudennec & Nicolas, 1977). The cells of ...
... Rizzino, 1983). Few EC cell lines are capable of spontaneous differentiation, and of these very few have the capacity to form cystic structures with phenotypic similarities to the postimplantation embryo (Rosenthal et al. 1970; Martin, Wiley & Damjanov, 1977; Cudennec & Nicolas, 1977). The cells of ...
Age-related changes in lymphocyte development and function
... cell numbers similar to those in young mice19. Because young and old mice from the same strain were analyzed, genetic effects alone cannot provide an explanation for this finding. Instead, these data make it necessary to consider that environmental factors are involved when decreases in B cell produ ...
... cell numbers similar to those in young mice19. Because young and old mice from the same strain were analyzed, genetic effects alone cannot provide an explanation for this finding. Instead, these data make it necessary to consider that environmental factors are involved when decreases in B cell produ ...
Synaptic basis for intense thalamocortical activation of feedforward
... stimulation during cell-attached recordings (Fig. 1b) were subsequently found, during whole-cell recordings, to directly inhibit their paired RS cells (17/20 pairs, data not shown). Inhibitory conductances tend to suppress responsiveness, so we reasoned that relatively large Gi values might contribu ...
... stimulation during cell-attached recordings (Fig. 1b) were subsequently found, during whole-cell recordings, to directly inhibit their paired RS cells (17/20 pairs, data not shown). Inhibitory conductances tend to suppress responsiveness, so we reasoned that relatively large Gi values might contribu ...
Cell cycle
The cell cycle or cell-division cycle is the series of events that take place in a cell leading to its division and duplication (replication) that produces two daughter cells. In prokaryotes which lack a cell nucleus, the cell cycle occurs via a process termed binary fission. In cells with a nucleus, as in eukaryotes, the cell cycle can be divided into three periods: interphase, the mitotic (M) phase, and cytokinesis. During interphase, the cell grows, accumulating nutrients needed for mitosis, preparing it for cell division and duplicating its DNA. During the mitotic phase, the cell splits itself into two distinct daughter cells. During the final stage, cytokinesis, the new cell is completely divided. To ensure the proper division of the cell, there are control mechanisms known as cell cycle checkpoints.The cell-division cycle is a vital process by which a single-celled fertilized egg develops into a mature organism, as well as the process by which hair, skin, blood cells, and some internal organs are renewed. After cell division, each of the daughter cells begin the interphase of a new cycle. Although the various stages of interphase are not usually morphologically distinguishable, each phase of the cell cycle has a distinct set of specialized biochemical processes that prepare the cell for initiation of cell division.