Perifosine, an oral bioactive novel alkylphospholipid
... Figure 1. Perifosine inhibits Akt phosphorylation and induces cytotoxicity in MM cells. (A) Baseline phosphorylation of Akt, STAT3, and ERK in MM cell lines and tumor cells from MM patients assessed by Western blotting. Lane 1 indicates MM.1S; 2, MM.1R; 3, U266; 4, INA-6; 5, RPMI8226; 6, LR5; 7, Dox ...
... Figure 1. Perifosine inhibits Akt phosphorylation and induces cytotoxicity in MM cells. (A) Baseline phosphorylation of Akt, STAT3, and ERK in MM cell lines and tumor cells from MM patients assessed by Western blotting. Lane 1 indicates MM.1S; 2, MM.1R; 3, U266; 4, INA-6; 5, RPMI8226; 6, LR5; 7, Dox ...
H3K4me3 demethylation by the histone
... HeLa cells, a PI histogram plot was generated for each sample and compared with other time points through a 3D representation. Synchronisation of HeLa cells Timings were set to obtain an optimal silencing of JARID1C at the time of release, using either double thymidine block or nocodozale treatment. ...
... HeLa cells, a PI histogram plot was generated for each sample and compared with other time points through a 3D representation. Synchronisation of HeLa cells Timings were set to obtain an optimal silencing of JARID1C at the time of release, using either double thymidine block or nocodozale treatment. ...
Article
... The emeraldine base form of polyaniline (EB) has been used as a hole transporting material in solid-state dye-sensitized TiO2 solar cells.9 EB that is protonated with different acids has been investigated as a holetransporting layer in polymer light emitting diodes, as a photoactive layer in Schottk ...
... The emeraldine base form of polyaniline (EB) has been used as a hole transporting material in solid-state dye-sensitized TiO2 solar cells.9 EB that is protonated with different acids has been investigated as a holetransporting layer in polymer light emitting diodes, as a photoactive layer in Schottk ...
Virus-transformed Pre-B Cells Show Ordered Activation but Not
... extremely useful models of individual developmental stages . These models have limitations, however. Being tumor cells, they might not represent normal cells with fidelity. Furthermore, they often display a mixed phenotype because individual cells appear to slowly progress through the lineage, where ...
... extremely useful models of individual developmental stages . These models have limitations, however. Being tumor cells, they might not represent normal cells with fidelity. Furthermore, they often display a mixed phenotype because individual cells appear to slowly progress through the lineage, where ...
Plant Cytokinesis Is Orchestrated by the Sequential Action of the
... The TRAPPII complex is required for cell plate biogenesis, and the exocyst is required for cell plate maturation. The TRAPPII complex sorts plasma membrane proteins, including exocyst subunits, at the cell plate throughout cytokinesis. We show that the two tethering complexes physically interact and ...
... The TRAPPII complex is required for cell plate biogenesis, and the exocyst is required for cell plate maturation. The TRAPPII complex sorts plasma membrane proteins, including exocyst subunits, at the cell plate throughout cytokinesis. We show that the two tethering complexes physically interact and ...
Chapter 2.3 Active Cell Processes: Motility, Muscle, and Mechanotransduction
... qualitative, and the models, to the extent they exist, more ad hoc. This is because not only are the processes much more complex, often involving a cascade of reactions or numerous individual cell functions, but they are also less well understood. We begin this chapter with a discussion of the vario ...
... qualitative, and the models, to the extent they exist, more ad hoc. This is because not only are the processes much more complex, often involving a cascade of reactions or numerous individual cell functions, but they are also less well understood. We begin this chapter with a discussion of the vario ...
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... development to term has been detected with these embryos. The results demonstrate that even when chromosomes from both parental sources are present in chimaeras, they fail to reach term unless both sets of chromosomes are present inside individual cells. However, the presence of some normal cells in ...
... development to term has been detected with these embryos. The results demonstrate that even when chromosomes from both parental sources are present in chimaeras, they fail to reach term unless both sets of chromosomes are present inside individual cells. However, the presence of some normal cells in ...
Diatom forms gametes (auxospore)
... GROWTH & REPRODUCTION Diatom life-cycle Asexual phase Cell divides into two copies of ...
... GROWTH & REPRODUCTION Diatom life-cycle Asexual phase Cell divides into two copies of ...
bacterial cell shape - Jacobs-Wagner Lab
... Box 1 | Determination and maintenance of cell shape The concepts of shape determination and shape maintenance are related but distinct. Determination refers to the guidance of something new, whereas maintenance refers to the preservation of something previously determined. In the case of a poured-co ...
... Box 1 | Determination and maintenance of cell shape The concepts of shape determination and shape maintenance are related but distinct. Determination refers to the guidance of something new, whereas maintenance refers to the preservation of something previously determined. In the case of a poured-co ...
Cell Cycle Phase Specificity and Biochemical
... RNA, and protein syntheses in L1210 cells required 0.5, 0.4, and 2 ¿tg of the drug per ml. Thus, LI 210 cells were about 4 to 5 times more sensitive than DON cells. Response of Synchronous DON Cells. Results with synchronous DON cells exposed for 1 hr in different phases of the cell cycle are shown ...
... RNA, and protein syntheses in L1210 cells required 0.5, 0.4, and 2 ¿tg of the drug per ml. Thus, LI 210 cells were about 4 to 5 times more sensitive than DON cells. Response of Synchronous DON Cells. Results with synchronous DON cells exposed for 1 hr in different phases of the cell cycle are shown ...
A Dictyostelium Mutant with Reduced Lysozyme Levels
... knocked out by homologous recombination. The mutant cells had greatly reduced enzymatic activity and grew inefficiently when bacteria were the sole food source. Over time the mutant gained the ability to internalize bacteria more efficiently, so that the defect in digestion was compensated by increa ...
... knocked out by homologous recombination. The mutant cells had greatly reduced enzymatic activity and grew inefficiently when bacteria were the sole food source. Over time the mutant gained the ability to internalize bacteria more efficiently, so that the defect in digestion was compensated by increa ...
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... Araldite or Spurr epoxy resin. Sections were cut on a Porter-Blum Mark II ultramicrotome and examined in a Siemens Elmiskop 1 electron microscope. Sections about 1 /cm thick were also cut and, after staining with a 1 % solution of toluidine blue, were examined by light microscopy. Statistical invest ...
... Araldite or Spurr epoxy resin. Sections were cut on a Porter-Blum Mark II ultramicrotome and examined in a Siemens Elmiskop 1 electron microscope. Sections about 1 /cm thick were also cut and, after staining with a 1 % solution of toluidine blue, were examined by light microscopy. Statistical invest ...
DNA Methylation Profiles Define Stem Cell Identity and
... profiles identify a cohort of developmentally regulated sequence elements, such as orphan CpG islands, that will be most valuable to uncover novel transcriptional regulators and pivotal ‘‘gatekeeper’’ genes in pluripotency and lineage differentiation. STEM CELLS 2012;30:2732–2745 ...
... profiles identify a cohort of developmentally regulated sequence elements, such as orphan CpG islands, that will be most valuable to uncover novel transcriptional regulators and pivotal ‘‘gatekeeper’’ genes in pluripotency and lineage differentiation. STEM CELLS 2012;30:2732–2745 ...
Biology - Prescott Unified School District
... Identify the causes of disease. Explain infectious diseases are transmitted. Describe how antibiotics fight infection. Compare and contrast findings in text to those of other sources (Viral Transmission) ...
... Identify the causes of disease. Explain infectious diseases are transmitted. Describe how antibiotics fight infection. Compare and contrast findings in text to those of other sources (Viral Transmission) ...
A scanning electron microscope study of the early
... Araldite or Spurr epoxy resin. Sections were cut on a Porter-Blum Mark II ultramicrotome and examined in a Siemens Elmiskop 1 electron microscope. Sections about 1 /cm thick were also cut and, after staining with a 1 % solution of toluidine blue, were examined by light microscopy. Statistical invest ...
... Araldite or Spurr epoxy resin. Sections were cut on a Porter-Blum Mark II ultramicrotome and examined in a Siemens Elmiskop 1 electron microscope. Sections about 1 /cm thick were also cut and, after staining with a 1 % solution of toluidine blue, were examined by light microscopy. Statistical invest ...
Biotic and abiotic elicitors induce biosynthesis and accumulation of
... combination, synergistically enhance metabolite production in cultured cells [10]. This is also the case of resveratrol accumulation in Vitis vinifera L. callus culture under the influence of biotic and abiotic elicitor combinations, such as fungal extract of Fusarium oxysporum and mannitol. It is k ...
... combination, synergistically enhance metabolite production in cultured cells [10]. This is also the case of resveratrol accumulation in Vitis vinifera L. callus culture under the influence of biotic and abiotic elicitor combinations, such as fungal extract of Fusarium oxysporum and mannitol. It is k ...
regulator of cell-plate formation in plant cytokinesis The NPK1
... MAPKKK family, and the kinase domain of NPK1 can replace the functions of several yeast MAPKKKs (Banno et al. 1993; Nishihama and Machida 2000). NPK1 and its Arabidopsis orthologous genes, ANP1/2/3, are transcribed in proliferating and division-competent cells or in organs rich in these cells, an ob ...
... MAPKKK family, and the kinase domain of NPK1 can replace the functions of several yeast MAPKKKs (Banno et al. 1993; Nishihama and Machida 2000). NPK1 and its Arabidopsis orthologous genes, ANP1/2/3, are transcribed in proliferating and division-competent cells or in organs rich in these cells, an ob ...
Molecular Mechanisms of Transforming Growth Factor
... Deregulation of TGF-b signaling is implicated in the pathogenesis of many diseases including arthritis, atherosclerosis, glomerulonephritis, human hereditary telangiectasia, and carcinogenesis. Loss of cellular sensitivity to TGFb-mediated growth inhibition may contribute directly to these pathologi ...
... Deregulation of TGF-b signaling is implicated in the pathogenesis of many diseases including arthritis, atherosclerosis, glomerulonephritis, human hereditary telangiectasia, and carcinogenesis. Loss of cellular sensitivity to TGFb-mediated growth inhibition may contribute directly to these pathologi ...
Formins: Linking Cytoskeleton and Endomembranes in Plant Cells
... thin layer of cortical cytoplasm between the plasmalemma and tonoplast, close to each other and in an intimate contact with the cortical cytoskeleton. Common to all eukaryotes, the endomembranes are interconnected either directly or through an intensive membrane turnover (recently reviewed in [1,2]) ...
... thin layer of cortical cytoplasm between the plasmalemma and tonoplast, close to each other and in an intimate contact with the cortical cytoskeleton. Common to all eukaryotes, the endomembranes are interconnected either directly or through an intensive membrane turnover (recently reviewed in [1,2]) ...
Gap junctions between optic nerve head astrocytes.
... metabolic coupling.11 In electrical coupling, a current applied to one cell spreads to its coupled neighboring cell to a greater degree than would be expected from their physical closeness. Ions seem to pass from one cell to the next via lowresistance pathways. Since all cells with electrical coupli ...
... metabolic coupling.11 In electrical coupling, a current applied to one cell spreads to its coupled neighboring cell to a greater degree than would be expected from their physical closeness. Ions seem to pass from one cell to the next via lowresistance pathways. Since all cells with electrical coupli ...
unresponsive to cell division control by polypeptide mating hormone
... least four gene products perform essential functions at start (Reed, S ., in press). Cell division in S. cerevisiae is controlled at start both by polypeptide hormones and by nutrients . Polypeptide hormones are produced by each of the two mating types, a-factor by MA Th cells (1) and a-factor by MA ...
... least four gene products perform essential functions at start (Reed, S ., in press). Cell division in S. cerevisiae is controlled at start both by polypeptide hormones and by nutrients . Polypeptide hormones are produced by each of the two mating types, a-factor by MA Th cells (1) and a-factor by MA ...