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Hearing
Hearing

... • Each crista has supporting cells and hair cells that extend into gel-like mass called ampullary cupula • Dendrites of vestibular nerve fibers encircle base of hair cells © 2013 Pearson Education, Inc. ...
Protein Synthesis within Dendrites: Glycosylation
Protein Synthesis within Dendrites: Glycosylation

... However, it is not known whether these organelles participate in the local synthesis and processing of proteins. The goal of the present study was to define whether the machinery for protein glycosylation is present in the dendrites of hippocampal neurons in culture. These are the same cells in whic ...
Myosin X is a downstream effector of PI(3)K during phagocytosis articles
Myosin X is a downstream effector of PI(3)K during phagocytosis articles

... Myo10 containing the tail of Myo10 (Myo10 tail) in a sub-line of RAW 264.7 cells resulted in a 79% ± 2% reduction of EIgG (antibody-coated erythrocytes) phagocytosis, compared to nonexpressing control cells (p < 0.001). We determined which domains of Myo10 were responsible for the inhibition of phag ...
Surviving apoptosis: life–death signaling in single cells
Surviving apoptosis: life–death signaling in single cells

... hepatic injury [44,45]. TRAIL is involved in nonapoptotic forms of cellular differentiation, with reported roles in hematopoiesis and intestinal and skeletal muscle differentiation [46–48]. TRAIL promotes survival, migration, and proliferation of human vascular endothelial cells and smooth muscle ce ...
fine structure and morphogenic movements in the
fine structure and morphogenic movements in the

... Some vacuoles are embedded in a network of membranes and tubules and appear to be filled with a homogeneous electron-transparent material. The masses of membranes which surround the vacuoles and continue into the cell neck are not arranged in any discernible pattern. In some areas, the membranes app ...
1001parotid oncocytic lesions review
1001parotid oncocytic lesions review

Cholesterol Metabolism_MJH
Cholesterol Metabolism_MJH

... Many of the reactions involved in converting lanosterol to cholesterol and other steroids are catalyzed by members of the cytochrome P450 enzyme superfamily. The human genome encodes 57 members of the cyt P450 superfamily, with tissue-specific expression and intracellular localization highly regula ...
PDF
PDF

... in contact with the endodermal precursor (E.x), and a somatic daughter, D, which was in contact with the C daughter cell (C.x) (3/3 cases) (Fig. 1D), as observed in intact embryos (20/20 cases). However, we were surprised to find that the P4 cell in the P2 isolates was frequently generated in an inv ...
Proteins - virtual laboratories
Proteins - virtual laboratories

The regulation and function of Class III PI3Ks: novel roles for Vps34
The regulation and function of Class III PI3Ks: novel roles for Vps34

... domain fold in the PI3Ks is related to that of PLCγ (phospholipase Cγ ), and is likely to be involved with interactions with acidic phospholipids rather than Ca2+ [22]. The helical domain has an important regulatory role in Class IA PI3K catalytic domains, where it mediates inhibitory contacts with ...
10 m
10 m

...  In this case, anaphase does not begin if any kinetochores remain unattached to spindle microtubules  Attachment of all of the kinetochores activates a regulatory complex, which then activates the enzyme separase  Separase allows sister chromatids to separate, triggering the onset of anaphase ...
Cell adhesion and phagocytosis promoted by monoclonal
Cell adhesion and phagocytosis promoted by monoclonal

... cells remaining attached to the dishes were solubilized with O'lml of 2 % sodium dodecyl sulphate. Samples of nonattached and attached cells were mixed with 10 ml of Budget Solve (RPI Corp.), radioactivity was measured in a Beckman scintillation spectrometer, and the percentage of attached cells cal ...
TOPIC 1. CELL CHARACTERISTICS AND DIGESTIBILITIES What
TOPIC 1. CELL CHARACTERISTICS AND DIGESTIBILITIES What

... OVERALL DIGESTIBILITY AS SUM OF CWDP AND CSDP Overall digestibility can be considered to be the sum of the digestibilities of its parts. Thus the sum of the cel wall digestibility and cell soluble diges tibility is an estimate of overall diges tibili ty, providing that the relative contributions of ...
Gozo, Malta - Gozo College Boys` Secondary School
Gozo, Malta - Gozo College Boys` Secondary School

Ezrin: a protein requiring conformational activation to link
Ezrin: a protein requiring conformational activation to link

... The plasma membrane is the interface a cell has with its environment and its neighbors. It is the site of vectorial transport of ions and nutrients, reception of signalling molecules, and attachments to adjacent cells and the extracellular matrix. To perform these functions, the membrane is supporte ...
The chimeric leucine-rich repeat/extensin cell wall protein
The chimeric leucine-rich repeat/extensin cell wall protein

... creased resistance is required (Fry 1986). Extensins might also be more generally involved in plant development as regulators of cell wall expansion (Carpita and Gibeaut 1993) or as linkers between the cell wall and the plasma membrane (Knox 1995). In recent years, several key enzymes involved in ce ...
Annexins: multifunctional components of growth and adaptation
Annexins: multifunctional components of growth and adaptation

... Certain annexins such as AnxB12 from Hydra have the capacity to be soluble, peripheral, and integral proteins (Ladokhin and Haigler, 2005). Using molecular simulation and site-directed mutagenesis, Montaville et al. (2002) identified a consensus phosphatidylserine-binding site ([R/ K]XXXK-BC-helices ...
Lecture 7 - Biology of Cancer
Lecture 7 - Biology of Cancer

... killing would be required, corresponding to an additional dose of 6.9 Gy. Total dose is 69 + 6.9 = 75.9 Gy. Problem 3: During the course of radiotherapy, a tumor containing 109 cells receives 40 Gy. if the Do is 2.2. Gy, how many tumor cells will be left? Answer: If the Do is 2.2 Gy the D10 is: D10 ...
What Does the Microsporidian E. cuniculi Tell Us About the Origin of
What Does the Microsporidian E. cuniculi Tell Us About the Origin of

... would code for the 256 proteins that would carry out the bare essential cellular functions such as DNA replication, protein synthesis (translation and transcription), metabolism (glycolysis), and various membrane related functions. It was assumed that the minimal bacterial cell would be a minimal ce ...
Hydrogen peroxide-induced changes in intracellular pH of
Hydrogen peroxide-induced changes in intracellular pH of

... treatment (Fig 4), and this implies that H2O2 possibly activates plasma membrane H+-ATPase, which will cause a more acidification of cell wall. In plant cells, plasma membrane H+-ATPase is primarily responsible for generating membrane potential [28,29]. Therefore, changes in membrane potential may c ...
High Expression of the Tonoplast Aquaporin
High Expression of the Tonoplast Aquaporin

... real membrane barriers to such transport. In contrast, water and solutes that enter these principal conduits pass through living tissues and may encounter membrane barriers when they follow the transcellular path. Cell-to-cell flow can be a major transport route for water, although the extent to whi ...
Auditory system
Auditory system

... Conductive hearing loss - various problems in the middle ear which can reduce conduction of vibrations by the chain of ossicles from the tympanic membrane to the oval window Sensorineural hearing loss – is due to defects in any structure or cell from the cochlea to auditory centers of the brain, but ...
Analysis of the Golgi Apparatus in Arabidopsis Seed
Analysis of the Golgi Apparatus in Arabidopsis Seed

... cells, which are constitutively secreting cell wall components to all regions of the plasma membrane, is a stepwise process occurring from cis to trans and that different products can be synthesized in the same Golgi stack. A separate study showed that transport vesicles in clover root tips, another ...
Cellular Receptors and Signal Transduction in Molluscan
Cellular Receptors and Signal Transduction in Molluscan

... immune responses is well established. They participate in a variety of internal defense-related activities including microbial phagocytosis, multicellular encapsulation, and cell-mediated cytotoxicity reactions that are presumed to be initiated through foreign ligand binding to hemocyte receptors an ...
Characteristics of Bacteria Worksheet
Characteristics of Bacteria Worksheet

... plasmid instead of a proper nucleus. They also have many ribosomes which make proteins for the bacteria. The bacteria also have one or more pili (singular = pilus) sticking through the cell membrane. Bacteria use the pilus to trade pieces of its DNA with other bacteria during a process called conjug ...
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Endomembrane system

The endomembrane system is composed of the different membranes that are suspended in the cytoplasm within a eukaryotic cell. These membranes divide the cell into functional and structural compartments, or organelles. In eukaryotes the organelles of the endomembrane system include: the nuclear membrane, the endoplasmic reticulum, the Golgi apparatus, lysosomes, vesicles, endosomes and the cell membrane. The system is defined more accurately as the set of membranes that form a single functional and developmental unit, either being connected directly, or exchanging material through vesicle transport. Importantly, the endomembrane system does not include the membranes of mitochondria or chloroplasts.The nuclear membrane contains two lipid bilayers that encompass the contents of the nucleus. The endoplasmic reticulum (ER) is a synthesis and transport organelle that branches into the cytoplasm in plant and animal cells. The Golgi apparatus is a series of multiple compartments where molecules are packaged for delivery to other cell components or for secretion from the cell. Vacuoles, which are found in both plant and animal cells (though much bigger in plant cells), are responsible for maintaining the shape and structure of the cell as well as storing waste products. A vesicle is a relatively small, membrane-enclosed sac that stores or transports substances. The cell membrane, is a protective barrier that regulates what enters and leaves the cell. There is also an organelle known as the Spitzenkörper that is only found in fungi, and is connected with hyphal tip growth.In prokaryotes endomembranes are rare, although in many photosynthetic bacteria the plasma membrane is highly folded and most of the cell cytoplasm is filled with layers of light-gathering membrane. These light-gathering membranes may even form enclosed structures called chlorosomes in green sulfur bacteria.The organelles of the endomembrane system are related through direct contact or by the transfer of membrane segments as vesicles. Despite these relationships, the various membranes are not identical in structure and function. The thickness, molecular composition, and metabolic behavior of a membrane are not fixed, they may be modified several times during the membrane's life. One unifying characteristic the membranes share is a lipid bilayer, with proteins attached to either side or traversing them.
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