HGF and TGFβ1 differently influenced Wwox regulatory function on
... bone microenvironment [1, 2, 4, 25]. As shown in Fig. 1a, HGF rapidly and persistently enhanced Twist-protein level in nuclear extracts of 1833 cells, being ineffective on Snail, and pTwist1/Twist ratio increased between 1 and 8 h, returning thereafter to the starvation value. On the contrary, TGFβ1 ...
... bone microenvironment [1, 2, 4, 25]. As shown in Fig. 1a, HGF rapidly and persistently enhanced Twist-protein level in nuclear extracts of 1833 cells, being ineffective on Snail, and pTwist1/Twist ratio increased between 1 and 8 h, returning thereafter to the starvation value. On the contrary, TGFβ1 ...
Expression and Inhibition of the Carboxylating
... not appear to be regulated by pCO2 in either diatom. In T. pseudonana and T. weissflogii, net CO2 fixation was blocked by 3, 3-dichloro-2-(dihydroxyphosphinoyl-methyl)-propenoate (a specific inhibitor of PEPC), but was restored by about 50% and 80%, respectively, by addition of millimolar concentrat ...
... not appear to be regulated by pCO2 in either diatom. In T. pseudonana and T. weissflogii, net CO2 fixation was blocked by 3, 3-dichloro-2-(dihydroxyphosphinoyl-methyl)-propenoate (a specific inhibitor of PEPC), but was restored by about 50% and 80%, respectively, by addition of millimolar concentrat ...
Paraquat: An Oxidative Stress Inducer
... whole plant, as growing leaves and newly emerging roots. This often means that the herbicide not only needs to damage at the point of its absorption, but must also be translocated to parts of the plant not contacted by the herbicide during application. Paraquat is a cation formed by two pyridine rin ...
... whole plant, as growing leaves and newly emerging roots. This often means that the herbicide not only needs to damage at the point of its absorption, but must also be translocated to parts of the plant not contacted by the herbicide during application. Paraquat is a cation formed by two pyridine rin ...
Varicella-Zoster Virus-Infected Human Sensory Neurons Are
... apoptosis, others induce it, and some appear to perform both functions (34, 54). Inhibition of apoptosis is likely to enhance survival and spread, thereby maximizing the production of virus progeny during lytic infection or facilitating a persistent infection (7, 34, 54, 61, 70). In this respect, ce ...
... apoptosis, others induce it, and some appear to perform both functions (34, 54). Inhibition of apoptosis is likely to enhance survival and spread, thereby maximizing the production of virus progeny during lytic infection or facilitating a persistent infection (7, 34, 54, 61, 70). In this respect, ce ...
Molecular differences between the rostral and caudal halves of the
... express cytotactin (Tan et al. 1987), tenascin (Mackie et al. 1988) and butyrylcholinesterase activity (Layer et al. 1988), while the cells of the caudal half bind peanut lectin (Stern et al. 1986) and antibodies directed against a cytotactin-binding proteoglycan ('CTB-proteoglycan'; Tan et al. 1987 ...
... express cytotactin (Tan et al. 1987), tenascin (Mackie et al. 1988) and butyrylcholinesterase activity (Layer et al. 1988), while the cells of the caudal half bind peanut lectin (Stern et al. 1986) and antibodies directed against a cytotactin-binding proteoglycan ('CTB-proteoglycan'; Tan et al. 1987 ...
Sickle Cell Disease - MUHC Patient Education
... cells to become rigid, elongated and sickle shaped. Based on the literature and from our experience, most children with sickle cell hemoglobin C disease and some children with sickle cell beta-thalassemia often have milder symptoms. Your child’s sickle cell disease type was determined through a bloo ...
... cells to become rigid, elongated and sickle shaped. Based on the literature and from our experience, most children with sickle cell hemoglobin C disease and some children with sickle cell beta-thalassemia often have milder symptoms. Your child’s sickle cell disease type was determined through a bloo ...
Photosynthesis Research
... the shear forces generated between the coverslip and slide surfaces have caused about 15 grana to become sufficiently detached as to form a loop extending away from the main body of the chloroplast. Six grana in the loop are very conspicuous, and two arrows point to fine threads connecting grana just ...
... the shear forces generated between the coverslip and slide surfaces have caused about 15 grana to become sufficiently detached as to form a loop extending away from the main body of the chloroplast. Six grana in the loop are very conspicuous, and two arrows point to fine threads connecting grana just ...
DataSheet
... family. FGF family members possess broad mitogenic and cell survival activities, and are involved in a variety of biological processes, including embryonic development, cell growth, morphogenesis, tissue repair, tumor growth and invasion. This protein functions as a modifier of endothelial cell migr ...
... family. FGF family members possess broad mitogenic and cell survival activities, and are involved in a variety of biological processes, including embryonic development, cell growth, morphogenesis, tissue repair, tumor growth and invasion. This protein functions as a modifier of endothelial cell migr ...
Chloroplasts in living cells and the string-of
... In 1980, Wildman et al. (Bot Gaz 141: 24–36) proposed a three-dimensional model for chloroplast structure whereby the grana were arranged in non-overlapping rows, like beads on a string. This string-of-grana model was developed from phase microscope analysis of living cells and partially disrupted, ...
... In 1980, Wildman et al. (Bot Gaz 141: 24–36) proposed a three-dimensional model for chloroplast structure whereby the grana were arranged in non-overlapping rows, like beads on a string. This string-of-grana model was developed from phase microscope analysis of living cells and partially disrupted, ...
P-Glycoprotein Substrates and Antagonists Cluster into Two Distinct
... previously described (28). Then, 100 mg of total membranes were incubated for 15 min with 3H-azidopine in the presence or absence of the test compound. The membranes were photolabeled with a UV lamp (General Electric F15T8) on ice for 15 min. Laemmli’s buffer was added, and the samples were run on a ...
... previously described (28). Then, 100 mg of total membranes were incubated for 15 min with 3H-azidopine in the presence or absence of the test compound. The membranes were photolabeled with a UV lamp (General Electric F15T8) on ice for 15 min. Laemmli’s buffer was added, and the samples were run on a ...
chapter 1
... A system is an organization of two or more organs and associated structures working as a unit to perform a common function or set of functions; for example, the flow of blood through the body in the case of the circulatory system. Some organs serve more than one body system. The pancreas serves the ...
... A system is an organization of two or more organs and associated structures working as a unit to perform a common function or set of functions; for example, the flow of blood through the body in the case of the circulatory system. Some organs serve more than one body system. The pancreas serves the ...
The Arabidopsis repressor of light signaling SPA1
... SPA1::GUS-SPA1 lines showed full complementation of the leafsize phenotype of the parental spa triple mutant in short and long days (Fig. 4A,B; see Fig. S4B in the supplementary material). Phloem-specific as well as mesophyll-specific expression of GUSSPA1 under the control of the SUC2 and CAB3 prom ...
... SPA1::GUS-SPA1 lines showed full complementation of the leafsize phenotype of the parental spa triple mutant in short and long days (Fig. 4A,B; see Fig. S4B in the supplementary material). Phloem-specific as well as mesophyll-specific expression of GUSSPA1 under the control of the SUC2 and CAB3 prom ...
Laboratory Guide - Indiana University Bloomington
... tissues that make up the body. The main goal of the course is to better understand how structure and function are integrated in the molecules, cells, tissues, and organs of the body. A major theme of the lectures and the focus of the laboratory studies is the area of histology, the branch of biology ...
... tissues that make up the body. The main goal of the course is to better understand how structure and function are integrated in the molecules, cells, tissues, and organs of the body. A major theme of the lectures and the focus of the laboratory studies is the area of histology, the branch of biology ...
RA/FGF control Meis in PD limb development
... boundary if inserted at stages 23-24 (Fig. 3J and data not shown). In contrast, RA beads inserted at stages 22-24 always incorporated close to the S-Z boundary (Fig. 3C,E,G). Results in both amphibian and chicken models have shown that self-affinity is a property of limb cell PD identity, which dete ...
... boundary if inserted at stages 23-24 (Fig. 3J and data not shown). In contrast, RA beads inserted at stages 22-24 always incorporated close to the S-Z boundary (Fig. 3C,E,G). Results in both amphibian and chicken models have shown that self-affinity is a property of limb cell PD identity, which dete ...
Exclusion of Ribulose-1,5-bisphosphate Carboxylase/oxygenase
... Rubisco is degraded rapidly and its nitrogen is translocated into growing organs (Mae et al. 1983). Therefore, Rubisco degradation is closely related to photosynthesis and nitrogen economy in plants. However, little is known about the degradation process of Rubisco in senescing leaves (for reviews, ...
... Rubisco is degraded rapidly and its nitrogen is translocated into growing organs (Mae et al. 1983). Therefore, Rubisco degradation is closely related to photosynthesis and nitrogen economy in plants. However, little is known about the degradation process of Rubisco in senescing leaves (for reviews, ...
Enhancement of Murine Lymphokine-activated Killer Cell Activity by
... (12, 13). Because it is weakly immunogenic and highly tumorigenic, the major biological characteristics mimicking that of human disease, JC is a more suitable model for experimental immunotherapy than other chemically or virally induced mam mary tumor models. Using JC as the target, we have demon st ...
... (12, 13). Because it is weakly immunogenic and highly tumorigenic, the major biological characteristics mimicking that of human disease, JC is a more suitable model for experimental immunotherapy than other chemically or virally induced mam mary tumor models. Using JC as the target, we have demon st ...
Optical Imaging Tools for Early Detection
... • Cancer initiating and cancer sustaining cells • Root of the disease—Characterized, in part, by an absence of markers or shared stem cell markers, metabolically less active, and may be more “like” normal cells ...
... • Cancer initiating and cancer sustaining cells • Root of the disease—Characterized, in part, by an absence of markers or shared stem cell markers, metabolically less active, and may be more “like” normal cells ...
REVIEWS
... ATP binding/hydrolysis but by proton movement down the transmembrane electrochemical gradient. Few RND proteins have been well characterized. The family includes NPC-1, which is defective in Niemann–Pick disease and modulates subcellular lipid/cholesterol distribution36, and Dispatched in Drosophila ...
... ATP binding/hydrolysis but by proton movement down the transmembrane electrochemical gradient. Few RND proteins have been well characterized. The family includes NPC-1, which is defective in Niemann–Pick disease and modulates subcellular lipid/cholesterol distribution36, and Dispatched in Drosophila ...
Mesoderm commitment to hematopoiesis - Development
... lineages in immediate proximity to each other (Haar and Ackerman, 1971). This observation provided the basis for the hypothesis, first put forward in the early 1900s, that these lineages derive from a common bi-potential precursor, a cell termed the hemangioblast (Sabin, 1920; Murray, 1932; and revi ...
... lineages in immediate proximity to each other (Haar and Ackerman, 1971). This observation provided the basis for the hypothesis, first put forward in the early 1900s, that these lineages derive from a common bi-potential precursor, a cell termed the hemangioblast (Sabin, 1920; Murray, 1932; and revi ...
Morphine Modulates Mouse Hippocampal Progenitor Cell Lineages
... most well known role, Notch1 maintains NPCs in the undifferentiated state by inhibiting neuronal differentiation. It was reported that Notch1 inhibits neurogenesis by turning CSL-SKIP into an activator and stimulating the transcription of Hes1 and Hes5 [17]. Moreover, transient activation of Notch1 ...
... most well known role, Notch1 maintains NPCs in the undifferentiated state by inhibiting neuronal differentiation. It was reported that Notch1 inhibits neurogenesis by turning CSL-SKIP into an activator and stimulating the transcription of Hes1 and Hes5 [17]. Moreover, transient activation of Notch1 ...
Control of pathfinding by the avian trunk neural crest
... then section and stain the chimaeric embryo. The nuclei of the quail crest cells can be distinguished from those of the chick host because of their darker, punctate staining. Using this technique, she confirmed what was known about migratory routes from Weston's study (Le Douarin & Teillet, 1974). A ...
... then section and stain the chimaeric embryo. The nuclei of the quail crest cells can be distinguished from those of the chick host because of their darker, punctate staining. Using this technique, she confirmed what was known about migratory routes from Weston's study (Le Douarin & Teillet, 1974). A ...
Involvement of antimicrobial peptides in mussel defence
... Antimicrobial peptides are one of the innate immunity actors which were conserved along evolution. Last decade, they were purified from plants (Broekaert et al., 1995), invertebrates (Iwanaga et al., 1998; Bulet et al., 1999) and vertebrates (Lehrer and Ganz, 1999) and are suspected to be part of im ...
... Antimicrobial peptides are one of the innate immunity actors which were conserved along evolution. Last decade, they were purified from plants (Broekaert et al., 1995), invertebrates (Iwanaga et al., 1998; Bulet et al., 1999) and vertebrates (Lehrer and Ganz, 1999) and are suspected to be part of im ...
BGFK Blue Segment Student Handout
... The β-globin protein model is divided into three segments to facilitate folding. Each is coded a different color — blue, green or red — to make it easier to fold and assemble. In your kit you will find three MiniToobers (flexible foam-covered wires) colored blue, green or red to correspond with a de ...
... The β-globin protein model is divided into three segments to facilitate folding. Each is coded a different color — blue, green or red — to make it easier to fold and assemble. In your kit you will find three MiniToobers (flexible foam-covered wires) colored blue, green or red to correspond with a de ...