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Regulation of erythropoiesis
Regulation of erythropoiesis

...  Osteoblast is another cell type besides renal interstitial cells, hepatocytes, glial cells (out of 14) that can express EPO and induce erythropoiesis after VHL inactivtion;  New crosstalk between osteoblast and hematopoitic compartment, local production of EPO under hypoxia condition by osteoblas ...
The impact of abiotic factors on cellulose synthesis
The impact of abiotic factors on cellulose synthesis

... and plant growth, changes to osmotic pressure can directly affect plant growth (Lockhart, 1965; Geitmann and Ortega, 2009). Additionally, changes to osmotic conditions can alter cell expansion, especially of the roots, resulting in directional plant growth towards more favorable water conditions or ...
Raven/Johnson Biology 8e Chapter 05 – Answers 1. The description
Raven/Johnson Biology 8e Chapter 05 – Answers 1. The description

... A. Answer a is incorrect. The net movement of water into a cell occurs when the interior of the cell is more concentrated than the surrounding environment—that is, when the environment is hypotonic. The correct answer is d— B. Answer b is incorrect. In an isotonic environment there is no net movemen ...
Raven/Johnson Biology 8e
Raven/Johnson Biology 8e

... A. Answer a is incorrect. The net movement of water into a cell occurs when the interior of the cell is more concentrated than the surrounding environment—that is, when the environment is hypotonic. The correct answer is d— B. Answer b is incorrect. In an isotonic environment there is no net movemen ...
Intracellular Redox Compartmentation and ROS
Intracellular Redox Compartmentation and ROS

... Together with genetic and/or functional redundancy, this may be one reason why it has proved so difficult to identify generic ROS sensors and define discrete ROS signaling pathways. ...
refinement of an in vitro cell model for cytochrome p450 induction
refinement of an in vitro cell model for cytochrome p450 induction

... greatly facilitate the ability to develop drugs devoid of these possible negative traits. Such a model would offer the advantage of requiring less drug (,1 mg) and reducing the number of animals used. In addition, confounding factors such as bioavailability, blood, and liver levels of the drug would ...
vascular tissue differentiation and pattern formation in plants
vascular tissue differentiation and pattern formation in plants

... the plant hormones auxin and cytokinin are important for vascular differentiation (3, 77). A number of proteins and genes involved in different stages of tracheary element formation such as secondary wall thickening and cell death have been characterized using biochemical and subtractive hybridizati ...
Is ATP a Signaling Agent in Plants?
Is ATP a Signaling Agent in Plants?

... found to be stimulated by eATP. Most studies tested eATP in the millimolar range, but it is notable that Venus fly trap closure was accelerated by 100 ␮m eATP (Jaffe, 1973), a concentration consistent with receptor activity (animal P2X receptors may exhibit one-half maximal activation by over 300 ␮m ...
advanced electroporation techniques in biology and medicine
advanced electroporation techniques in biology and medicine

... electroporation pulses have high power but are very short. Thus, a power supply cannot generate the energy for the pulse during the pulse generation, but it has to be generated and stored into the capacitor before the generation of the pulse. This usually results in a voltage drop (ΔAL) during the p ...
pathological
pathological

... Pathogenesis of ARDS • ARDS initiated by injury to alveolar septal pneumocytes & endothelial cells • Endothelial activation from pneumocyte injury or circulating inflammatory mediators (e.g. sepsis) • Adhesion & extravasation of neutrophils into interstitium & alveoli  degranulation & release of m ...
Slits affect the timely migration of neural crest cells via robo receptor
Slits affect the timely migration of neural crest cells via robo receptor

... Background: Neural crest cells emerge by delamination from the dorsal neural tube and give rise to various components of the peripheral nervous system in vertebrate embryos. These cells change from nonmotile into highly motile cells migrating to distant areas before further differentiation. Mechanis ...
PDF - Oxford Academic - Oxford University Press
PDF - Oxford Academic - Oxford University Press

... translocation to the shoot via root pressure and the transpiration stream, K+ is delivered to the leaf apoplastic space outside the bundle sheath. It is then transferred to the phloem sap before allocation to aerial sink organs or recycling back to the root, the amount of recirculated K+ ultimately ...
Monolignol glucosides as intermediate compounds in
Monolignol glucosides as intermediate compounds in

... synthesis of coniferin and a slow turnover of this compound (Marcinowski and Grisebach 1977). The concentration of coniferin in differentiating xylem of Japanese black pine (Pinus thunbergii Parl.) is highest at the beginning of May, before the most active lignifying season, June and July, and there ...
The OBO Foundry Project
The OBO Foundry Project

... heterogeneous informatics systems. .. ontologies … formally define relationships between the concepts.” ...
Berlin-Buch - Max Delbrück Center for Molecular Medicine
Berlin-Buch - Max Delbrück Center for Molecular Medicine

... School in Berlin-Buch, the Franz Volhard Clinic for Cardiovascular Diseases as well as the Robert Rössle Cancer Clinic, are connected to the MDC. Regarding patient care, these two clinics are part of the HELIOS Clinics GmbH. The relationships of the MDC to the Charité’s neurobiological clinics secto ...
Unleashing the potential of the root hair cell as a
Unleashing the potential of the root hair cell as a

... Plant root is an organ composed of multiple cell types with different functions. This multicellular complexity limits our understanding of root biology because -omics studies performed at the level of the entire root reflect the average responses of all cells composing the organ. To overcome this dif ...
Phloem loading and unloading of sugars and amino acids
Phloem loading and unloading of sugars and amino acids

... aloft into the non-viscous aerial environment to capture light for photosynthetic reduction of carbon dioxide. The resulting nutritional interdependence of soil and aerial organs was solved by exchange of acquired nutrients between these regions. For terrestrial macrophytes, distances separating the ...
Plant Physiology
Plant Physiology

... also noted that many of the nodules elicited by EJ355 developed on the primary root and had a defined apical meristem. However, we have recently found that the EJ312 genetic background affects the expression of R. meliloti symbiotic genes (6). Accordingly, we have expanded our study of bacterial inv ...
CFTR modulates lung secretory cell proliferation and - AJP-Lung
CFTR modulates lung secretory cell proliferation and - AJP-Lung

... ratio of 1:2:1. Adult animals (75 days) from heterozygote-heterozygote matings treated in utero at 15–16 days gestation with the cftr gene were genotyped to evaluate the effect of transgene expression on genotype-specific survival. These data are presented in Table 1. The population ratios of adult ...
tissues
tissues

... matter (feces) (nitrogenous waste) ...
Animal Form and Function - Tanque Verde School District
Animal Form and Function - Tanque Verde School District

... matter (feces) (nitrogenous waste) ...
Water Metabolism and the Kidneys
Water Metabolism and the Kidneys

UNIT 1 – FORCE AND MOTION (SEPUP Force and
UNIT 1 – FORCE AND MOTION (SEPUP Force and

... basic units of structure and function in living things; and all presently existing cells arose from previously existing cells). B-2.2 Summarize the structures and functions of organelles found in a eukaryotic cell (including the nucleus, mitochondria, chloroplasts, lysosomes, vacuoles, ribosomes, en ...
Although ABA is mainly made in the leaves and the root cap, all
Although ABA is mainly made in the leaves and the root cap, all

... ABA-induced Ca2+ increase is mediated by second messengers, IP3 and cADPR. cADPR has been shown to induce cytosolic Ca2+ increase and stomatal closure in Commelina guard cells (Leckie et al., 1998). Also in tomato hypocotyls cells, microinjected cADPR induced ABA-inducible gene expression that can ...
Persistent Firing Supported by an Intrinsic Cellular
Persistent Firing Supported by an Intrinsic Cellular

... recording chamber and superfused with ACSF, maintaining the temperature in between 34 and 36°C for recordings. Patch pipettes were fabricated from borosilicate glass capillaries by means of a P-87 horizontal puller (Sutter Instrument). Patch pipettes were filled with intracellular solution containin ...
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Organ-on-a-chip

An organ-on-a-chip (OC) is a multi-channel 3-D microfluidic cell culture chip that simulates the activities, mechanics and physiological response of entire organs and organ systems. It constitutes the subject matter of significant biomedical engineering research, more precisely in bio-MEMS. The convergence of labs-on-chips (LOCs) and cell biology has permitted the study of human physiology in an organ-specific context, introducing a novel model of in vitro multicellular human organisms. One day, they will perhaps abolish the need for animals in drug development and toxin testing.Although multiple publications claim to have translated organ functions onto this interface, the movement towards this microfluidic application is still in its infancy. Organs-on-chips will vary in design and approach between different researchers. As such, validation and optimization of these systems will likely be a long process. Organs that have been simulated by microfluidic devices include the heart, the lung, kidney, artery, bone, cartilage, skin and more.Nevertheless, building valid artificial organs requires not only a precise cellular manipulation, but a detailed understanding of the human body’s fundamental intricate response to any event. A common concern with organs-on-chips lies in the isolation of organs during testing. ""If you don’t use as close to the total physiological system that you can, you’re likely to run into troubles"" says William Haseltine, founder of Rockville, Maryland. Microfabrication, microelectronics and microfluidics offer the prospect of modeling sophisticated in vitro physiological responses under accurately simulated conditions.
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