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Synthetic membrane transporters J Middleton Boon and Bradley D
Synthetic membrane transporters J Middleton Boon and Bradley D

... Pohorille and colleagues [1,2] have performed molecular dynamics simulations of unassisted Na+ and Cl– ion transport across a bilayer membrane. As the ion enters the outer monolayer, it generates a deep, local defect that allows solvated water molecules and polar phospholipid head-groups to also ent ...
Renal exam 2006
Renal exam 2006

... 12. A 35-year-old woman comes to see you for a physical exam. She is mildly obese, the blood pressure is 138/82, and the rest of the exam is normal. Over two ensuing visits, her blood pressure is 136/84 and 132/88. She has a normal electrocardiogram and urine analysis and the BUN is 11 mg/dL with a ...
Cue-Signal-Response Analysis of TNF-Induced
Cue-Signal-Response Analysis of TNF-Induced

... Cue–signal–response relationships in cell signaling are ripe for applying multivariate analysis techniques, such as PLS, to tease out the key biochemical changes associated with critical cell decisions. However, assaying cell signaling involves the measurement of a wide range of parameters including ...
THE ROLE OF MHC GENE PRODUCTS IN IMMUNE REGULATION AND
THE ROLE OF MHC GENE PRODUCTS IN IMMUNE REGULATION AND

... cell immunity and of T cell immune regulation has evolved with particular emphasis on the genes of the MHC and the molecules for which they code that regulate essential immune mechanisms. Carrier Function and the Specificity of T Lymphocytes The pioneering experiments of Landsteiner (21) established ...
Interstitial fluid
Interstitial fluid

... • It has a higher content of protein and contains white blood cells, (its protein content will vary according to which tissue it penetrates).(thus containing proteins , fat absorbed from intestine , waste products , antibodies and lymphocytes .) • Formation of lymph: filtration forces water and diss ...
ochromonas malhamensis
ochromonas malhamensis

... ribonuclease (E .C . 2 .7.7 .16 ribonucleate nucleotido-2'-transferase) were done on Ochromonas cultures in the same experimental treatments and under identical assay conditions as the cytochemical study . During starvation, the acid hydrolase specific activities were consistently twice those found ...
Atypical Regulation of a Green Lineage-Specific B
Atypical Regulation of a Green Lineage-Specific B

... of mitosis (Magyar et al., 1997; Mészáros et al., 2000; Dewitte and Murray, 2003; Lee et al., 2003). Furthermore, in rice (Oryza sativa), the mitotic CyclinB2;2 was shown to activate CDKB2;1, and both proteins colocalize on chromosomes at metaphase, suggesting that this complex may be involved in ...
Cytoskeletal control of plant cell shape: getting the fine points
Cytoskeletal control of plant cell shape: getting the fine points

... conical shapes of petal epidermal cells affect their optical properties so as to enhance coloration. The shapes of plant cells are de®ned by their walls, and are acquired during development according to the patterns in which walls expand during organ and cell growth. Cell expansion depends on the ab ...
renal ppt ck pt 2
renal ppt ck pt 2

... – Most Na, Cl is reabsorbed in the PCT, some in the collecting ducts by aldosterone – K is reabsorbed in the PCT and the ascending loop of Henle – Bicarb, Ca and Phosphate are in the PCT – Glucose is reabsorbed up to 220mg/dl > will be excreted ...
research article Numerical study of the electroporation pulse shape
research article Numerical study of the electroporation pulse shape

... world and for this reason it has drawn the attention of many researchers. Chemotherapy has been used for many years and is one of the most common treatments for cancer. Cytotoxic chemotherapeutic drugs are usually hydrophilic with very low transport through the cell membrane and thus high doses of t ...
ppt
ppt

... Digestion is the breakdown of nutrients to a level that can be used by cells of the body. Structures  GI tract (mouth, pharynx, esophagus, stomach, small intestine, large intestine) ...
Chromosomal Changes without DNA
Chromosomal Changes without DNA

... of that gene's product also increases (1). In mammalian cells, the most frequently studied system is the development of re sistance to methotrexate by amplification of the DHFR1 gene (2, 3). This process has been studied primarily in cultured cells; amplification events in mammalian cells have been ...
Parenchyma cells
Parenchyma cells

... Parenchyma – Aerenchyma A lattice cell structure is common in the aerenchyma of several aquatic plants including water hyacinth (Eichhornia) and pickerelweed (Pontederia). This honeycomb effect provides stability and strength with a minimum of structural material and the air spaces provide buoyancy ...
Paper 1 - TheAllPapers
Paper 1 - TheAllPapers

... Which statement explains why this occurs? A ...
The ARP2/3 complex: giving plant cells a leading edge
The ARP2/3 complex: giving plant cells a leading edge

... protrusion could be related to a more fundamental actin polymerization-based form of motility that is exhibited by certain microorganisms and endosymbiotic subcellular organelles.(2–4) Recent studies reveal that certain molecular components in expanding, non-motile, plant cells(5–18) bear strong sim ...
ReviewFinalExamAnatomyB
ReviewFinalExamAnatomyB

... 44. Describe the exchanges that occur across capillary walls. 45. Explain how regular exercise and a diet low in fats and cholesterol may help maintain cardiovascular health. ...
Link to Unit 4.0
Link to Unit 4.0

... Where’d that come from? - This is a lab activity resource to accompany learning of photosynthesis and the Calvin cycle. Students are able to measure change in water conditions and gaseous production associated with autotrophs.  Photosynthesis Virtual Manipulative - students will understand how plan ...
A gain-of-function mutant of Munc18-1 stimulates secretory granule
A gain-of-function mutant of Munc18-1 stimulates secretory granule

... addition, Munc18-1 may undergo all three modes of interaction [25,38,39], and modes 2 and 3 are required for Munc18-1 to stimulate membrane fusion kinetics in vitro [25]. Mode 1 binding has only been observed with Munc18-1 and its role in exocytosis has been debated. It has been suggested that this ...
Cell Cycle-specific Effects of Tumor Necrosis
Cell Cycle-specific Effects of Tumor Necrosis

... treated with 0.88 >tg TNF per flask. Beginning from 0 time, individual cultures were harvested by trypsinization at hourly intervals up to the 12th hr. Care was taken to collect both cells that were attached to dishes (removed by trypsinization) and cells floating in the medium. The latter consisted ...
On the mechanisms of nectar secretion: revisited
On the mechanisms of nectar secretion: revisited

... these systems appears to be similar to that occurring in nectaries devoid of their own phloem. Based on recent information regarding the cell ultrastructure and physiology of nectaries, as well as the mechanisms of sugar transport across membranes, I have proposed a new mechanism of nectar secretion ...
The Molecular Basis of Life
The Molecular Basis of Life

... Test for macromolecules found in living organisms. Use three-dimensional models of important compounds. ...
Voltage-dependent Ionic Conductances of Type I Spiral Ganglion
Voltage-dependent Ionic Conductances of Type I Spiral Ganglion

... to the cochlear nucleus. While single-unit studies conducted over the past several decades have provided a wealth of information concerning the response characteristics of these neurons and, to some extent, their receptor targets, little is known about the neuron’s intrinsic electrical properties. T ...
Author`s personal copy - Ruhr
Author`s personal copy - Ruhr

... firing made it difficult to control precisely the firing pattern of the neuron. In addition, the precise cellular mechanism by which these constructs regulated neuronal firing was not investigated. The induction of neuronal firing might be mediated through a decrease in K+ conductance, for example, ...
Evolutionary tradeoffs in cellular composition across
Evolutionary tradeoffs in cellular composition across

... One of the most important classic and contemporary interests in biology is the connection between cellular composition and physiological function. Decades of research have allowed us to understand the detailed relationship between various cellular components and processes for individual species, and ...
Sensing of Osmotic Pressure Changes in Tomato Cells
Sensing of Osmotic Pressure Changes in Tomato Cells

... Cells of tomato (Lycopersicon esculentum) growing in suspension gradually depleted their culture medium and caused a steady decrease in its osmolality. When confronted with a sudden change in medium osmolality (a hypo-osmotic or hyperosmotic shock), respectively, these cells responded with volume ch ...
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Organ-on-a-chip

An organ-on-a-chip (OC) is a multi-channel 3-D microfluidic cell culture chip that simulates the activities, mechanics and physiological response of entire organs and organ systems. It constitutes the subject matter of significant biomedical engineering research, more precisely in bio-MEMS. The convergence of labs-on-chips (LOCs) and cell biology has permitted the study of human physiology in an organ-specific context, introducing a novel model of in vitro multicellular human organisms. One day, they will perhaps abolish the need for animals in drug development and toxin testing.Although multiple publications claim to have translated organ functions onto this interface, the movement towards this microfluidic application is still in its infancy. Organs-on-chips will vary in design and approach between different researchers. As such, validation and optimization of these systems will likely be a long process. Organs that have been simulated by microfluidic devices include the heart, the lung, kidney, artery, bone, cartilage, skin and more.Nevertheless, building valid artificial organs requires not only a precise cellular manipulation, but a detailed understanding of the human body’s fundamental intricate response to any event. A common concern with organs-on-chips lies in the isolation of organs during testing. ""If you don’t use as close to the total physiological system that you can, you’re likely to run into troubles"" says William Haseltine, founder of Rockville, Maryland. Microfabrication, microelectronics and microfluidics offer the prospect of modeling sophisticated in vitro physiological responses under accurately simulated conditions.
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