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interaction between tumor and immune system: the role of tumor cell
interaction between tumor and immune system: the role of tumor cell

... caspase-dependent or caspase-independent pathways [17]. CD40 expansion and its activation is often accompanied by expression of co-stimulatory and adhesion molecules, Fas-antigen etc.CD40 may interact with myeloid-derived suppressor cells (MDSC) and regulatory T cells (Treg) [18]. Nowadays it became ...
Clinical Spectrum of Cutaneous Langerhans` Cell Histiocytosis
Clinical Spectrum of Cutaneous Langerhans` Cell Histiocytosis

... Langerhans’ cell histiocytosis summarizes a spectrum of diseases on the basis of histogenetic criteria. These are characterized by an accumulation of cells with Langerhans’ cell phenotype in one or multiple organs. Up to 50% of patients with either single or multi-organ manifestation of Langerhans’ ...
Total credit hours = 4 - College of Micronesia
Total credit hours = 4 - College of Micronesia

... 1.1 Define and describe the general steps in the scientific method, differentiate inductive and deductive reasoning, explain how hypotheses are formed, identify variables, and elaborate upon the reasons why, and the ways in which, a scientist conducts ...
PH Balance and You - Midwest Health and Wellness
PH Balance and You - Midwest Health and Wellness

... we have the highest alkaline mineral concentration and also the highest body pH. From that point on, the normal process of life is to gradually acidify. That is why these degenerative diseases do not occur as often when you are young. Reverse aging requires two separate steps: chemical and physical. ...
The Excretory System - Avery County Schools
The Excretory System - Avery County Schools

... 5 Urine is the result of your body balancing the amount of water and salts in your body. Your kidneys pull harmful substances out of your blood. They also help you when you haven't been drinking much water. They create less urine and your body loses less water. Your body doesn't run out of fluid as ...
circulatory system
circulatory system

... The large arteries have thick walls of elastic-like tissue that enables them to withstand the blood pressure created by the heart’s beating. ...
circulatory system - Livingstone High School
circulatory system - Livingstone High School

... The large arteries have thick walls of elastic-like tissue that enables them to withstand the blood pressure created by the heart’s beating. ...
Identification of a Cell Cycle-Related Cene, Cyclin, in Nicotiana
Identification of a Cell Cycle-Related Cene, Cyclin, in Nicotiana

... fragment from a cDNA obtained by reverse transcription on vegetative bud total RNA. This was subcloned in the Smal site of pUC18, confirmed by sequencing, and used as a probe to screen a cell-suspension cDNA library. ...


... of California, and Veterans Affairs Medical Center I I 1-H. 3350 La Jolla Village ...
Supported by: Body Systems and ABO blood types Grade 6 Lesson
Supported by: Body Systems and ABO blood types Grade 6 Lesson

... 2. Explain to the students how a system is a group of interrelated, interacting, or interdependent parts forming a complex whole. 3. Next, ask students, “How does the human body act as a system?” 4. Use students’ answers and explain that the human body has many parts that interact and interdependen ...
Hydroxyapatite/Nanodiamond Hydrogels as Potential Materials for
Hydroxyapatite/Nanodiamond Hydrogels as Potential Materials for

... The UV-vis absorption spectrum of tetracycline hydrochloride in water is typical at 361 nm, using the calibration curves (A1%1cm = 337 for tetracycline hydrochloride both evaluated in PB, pH 6.8). Three replicate measurements were performed for each designed formulation [19,20]. Each sample was repl ...
The Cyclin-Dependent Kinase Inhibitor KRP6 Induces Mitosis and
The Cyclin-Dependent Kinase Inhibitor KRP6 Induces Mitosis and

... (Inzé and De Veylder, 2006). The model plant species Arabidopsis encodes up to 12 CDKs and 49 CYCs that have been categorized into different classes according to their sequence similarity (Vandepoele et al., 2002; Wang et al., 2004; Menges et al., 2005). Plants possess six types of CDKs. The A-type ...
Molten rocks in motion
Molten rocks in motion

Archaebacteria These unusual bacteria are genealogically neither
Archaebacteria These unusual bacteria are genealogically neither

... motile ones were considered to be ani­ mals and the ones that appeared not to move, including the bacteria, were con­ sidered to be plants. As understanding of the microscopic world advanced it became apparent that a simple twofold classification would not suffice, and so additional categories were ...
1 US ARMY MEDICAL DEPT. CENTER AND SCHOOL
1 US ARMY MEDICAL DEPT. CENTER AND SCHOOL

... Total lung capacity--volume of gas contained in the lung at the end of maximal inhalation-6000 cc. ...
THE IMPACT OF MOLLUSCICIDES ON ENZYME ACTIVITIES IN
THE IMPACT OF MOLLUSCICIDES ON ENZYME ACTIVITIES IN

... Cloethocarb, the reaction in the most basal par1s of the cells is more intense than in controls or after 0.01% Cloethocarb, which is similar to that in controls (compare Figs. 6 and 7). Vesicles in the digestive cells stain less and reaction in the excretory cell is more distinct than in controls. M ...
JCB Raver1, a dual compartment protein, is a ligand for
JCB Raver1, a dual compartment protein, is a ligand for

... at microfilament sarcolemma attachment sites (costameres) in skeletal muscle (Morris and Fulton, 1994). For tropomyosins, it was shown that mRNAs coding for different splice forms target to discrete subcellular sites during the development of neuronal polarity (Hannan et al., 1995). Although several ...
Growth-factor-related proteins that are inducers in early
Growth-factor-related proteins that are inducers in early

Blood cell formation
Blood cell formation

...  A foreign protein (antigen) may be attacked by the immune system  Blood is “typed” by using antibodies that will cause blood with certain proteins to clump (agglutination) ...
Fibronectins Are Essential for Heart and Blood Vessel
Fibronectins Are Essential for Heart and Blood Vessel

... IBRONECTINS (FNs) are major components of the extracellular matrix and blood plasma, and are specific ligands for several integrin adhesion receptors.1-3 In vitro, FNs have been shown to function in cell adhesion, migration, and extracellular matrix assembly.4,5 Wide expression of FNs in vivo sugges ...
Multiscale View of Cytoskeletal Mechanoregulation of Cell and
Multiscale View of Cytoskeletal Mechanoregulation of Cell and

... cells into a specific niche (Williams and Fuchs 2013; Vorhagen and Niessen 2014). Polarity also plays a key role in cells’ ability to execute many biological functions, such as migrating directionally as individuals or collectively (Vicente-Manzanares et al. 2009; Devreotes and Horwitz 2015). It is ...
Understanding Activity in Electrically Coupled Networks Using PRCs
Understanding Activity in Electrically Coupled Networks Using PRCs

... In this chapter, we describe how PRCs and weakly coupled oscillator theory can be used to understand activities produced by electrically coupled cells. For space reasons, we take a narrow focus, only considering electrical coupling between pairs of spiking neurons in cortical systems and related the ...
Anemia in Chronic Kidney Disease - National Institute of Diabetes
Anemia in Chronic Kidney Disease - National Institute of Diabetes

... The National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK), through its Division of Kidney, Urologic, and Hematologic Diseases, supports several programs and studies devoted to improving treatment for people with CKD and kidney failure. One group of NIDDKsupported researchers is co ...
Cytokinesis failure occurs in Fanconi anemia pathway
Cytokinesis failure occurs in Fanconi anemia pathway

Carbon Monoxide Signature in Human Body: Measured Data and
Carbon Monoxide Signature in Human Body: Measured Data and

... A New thinking that very slow expiration rate greater than ~20 seconds has potential to generate a tidal volume CO concentration of 20 ppm or greater. This fundamental tidal volumetric rate change and its relation to the CO concentration increase in the circulatory system of human body is a subject ...
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Organ-on-a-chip

An organ-on-a-chip (OC) is a multi-channel 3-D microfluidic cell culture chip that simulates the activities, mechanics and physiological response of entire organs and organ systems. It constitutes the subject matter of significant biomedical engineering research, more precisely in bio-MEMS. The convergence of labs-on-chips (LOCs) and cell biology has permitted the study of human physiology in an organ-specific context, introducing a novel model of in vitro multicellular human organisms. One day, they will perhaps abolish the need for animals in drug development and toxin testing.Although multiple publications claim to have translated organ functions onto this interface, the movement towards this microfluidic application is still in its infancy. Organs-on-chips will vary in design and approach between different researchers. As such, validation and optimization of these systems will likely be a long process. Organs that have been simulated by microfluidic devices include the heart, the lung, kidney, artery, bone, cartilage, skin and more.Nevertheless, building valid artificial organs requires not only a precise cellular manipulation, but a detailed understanding of the human body’s fundamental intricate response to any event. A common concern with organs-on-chips lies in the isolation of organs during testing. ""If you don’t use as close to the total physiological system that you can, you’re likely to run into troubles"" says William Haseltine, founder of Rockville, Maryland. Microfabrication, microelectronics and microfluidics offer the prospect of modeling sophisticated in vitro physiological responses under accurately simulated conditions.
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