• Study Resource
  • Explore Categories
    • Arts & Humanities
    • Business
    • Engineering & Technology
    • Foreign Language
    • History
    • Math
    • Science
    • Social Science

    Top subcategories

    • Advanced Math
    • Algebra
    • Basic Math
    • Calculus
    • Geometry
    • Linear Algebra
    • Pre-Algebra
    • Pre-Calculus
    • Statistics And Probability
    • Trigonometry
    • other →

    Top subcategories

    • Astronomy
    • Astrophysics
    • Biology
    • Chemistry
    • Earth Science
    • Environmental Science
    • Health Science
    • Physics
    • other →

    Top subcategories

    • Anthropology
    • Law
    • Political Science
    • Psychology
    • Sociology
    • other →

    Top subcategories

    • Accounting
    • Economics
    • Finance
    • Management
    • other →

    Top subcategories

    • Aerospace Engineering
    • Bioengineering
    • Chemical Engineering
    • Civil Engineering
    • Computer Science
    • Electrical Engineering
    • Industrial Engineering
    • Mechanical Engineering
    • Web Design
    • other →

    Top subcategories

    • Architecture
    • Communications
    • English
    • Gender Studies
    • Music
    • Performing Arts
    • Philosophy
    • Religious Studies
    • Writing
    • other →

    Top subcategories

    • Ancient History
    • European History
    • US History
    • World History
    • other →

    Top subcategories

    • Croatian
    • Czech
    • Finnish
    • Greek
    • Hindi
    • Japanese
    • Korean
    • Persian
    • Swedish
    • Turkish
    • other →
 
Profile Documents Logout
Upload
Lecture 11 DFT for periodic crystalline solids CHEM6085: Density
Lecture 11 DFT for periodic crystalline solids CHEM6085: Density

Forage digestibility: the intersection of cell wall lignification and plant
Forage digestibility: the intersection of cell wall lignification and plant

... system (NDF minus ADF and ADF minus ADL, respectively), the loss of lignin at the ADF step results in concentration over-estimates of these cell wall polysaccharides (Theander and Westerlund, 1993). These comments are not meant to belittle the detergent system as it has been of great value in rumina ...
Octamer-binding transcription factors: genomics and functions
Octamer-binding transcription factors: genomics and functions

... of the Oct transcription factors. It is ubiquitously expressed in many tissues and cells and either positively or negatively regulates the expression of a variety of genes. These genes include the RNA polymerase II-transcribed and ubiquitously expressed histone H2B gene (49, 50), tissuespecific immu ...
File
File

... – Pulmonary veins empty oxygenated blood into the left atrium – Blood flows through the mitral valve to the left ventricle – From the left ventricle blood flows through the aortic valve to the ...
Key Stage 3 Biology Specification
Key Stage 3 Biology Specification

... • Describe how cells in the leaf and root are adapted for photosynthesis and for taking in water • Learn about the importance of photosynthesis to humans and other animals • Describe the relationship between photosynthesis and respiration in plants Unit 9D: Plants for Food • Learn about humans as pa ...
Anticancer Properties of Cardiac Glycosides
Anticancer Properties of Cardiac Glycosides

... melanoma cells in the G2/M phase of the cell cycle [34]. In lung cancer cells, bufalin upregulates p21 WAF1 and suppresses cyclin D expression in response to the activation of p53 [35]. Because the tumor suppressor p21 WAF1 acts as a potent inhibitor of cell cycle progression [36] and because cyclin ...
Chronic Kidney Disease - Kidney Health Australia
Chronic Kidney Disease - Kidney Health Australia

... CKD - Stage 1 (kidney function 90-100%) In Stage 1, the estimated GFR is usually > 90mL/min and the serum creatinine level is usually normal. Overall kidney function is good but the kidneys show other signs of disease. This may be protein loss into the urine or structural damage seen on an X-ray or ...
Facultad de Ciencias Tráfico de células dendríticas a través
Facultad de Ciencias Tráfico de células dendríticas a través

... until the thoracic ducts, where lymph is poured into the blood vascular system through subclavian veins. In order to accomplish its draining function, the lymphatic capillaries form an intricate network inside the tissue, in close contact with blood vessels, but without anastomose with them. The mai ...
Interaction with PI3-kinase contributes to the cytotoxic activity ofApoptin S Maddika
Interaction with PI3-kinase contributes to the cytotoxic activity ofApoptin S Maddika

... and L929 cell lysates with either GST or GST–apoptin. The proteins cloned in PGEX-2T (Amersham Biosciences, Mississauga, ON, Canada) were along with the different cell lysates immobilized on glutathione sepharose beads overnight at 4 1C. The beads were washed thrice with ice-cold lysis buffer and bo ...
Roles of vaccinia virus EEV-specific proteins in intracellular actin tail
Roles of vaccinia virus EEV-specific proteins in intracellular actin tail

... host cell that determines if actin tails are formed. However, it was noticeable that the number of actin tails varied with cell type and HeLa cells produced appreciably more intracellular actin tails than BS-C-1 cells (compare Fig. 1 a and 1 d and Fig. 2 a with Fig. 3 a and 3 b). It was possible tha ...
Set 5 - Thorpes Education
Set 5 - Thorpes Education

... value, and useful chiefly for the study of the perversion of truth by memory,” while Paul Radin contended that investigators rarely spent enough time with the tribes they were observing, and inevitably derived results too tinged by the investigator’s own emotional tone to be reliable. Even more impo ...
What is separated in bioseparation?
What is separated in bioseparation?

... • In reactive bioprocessing, the bioseparation process follows some form of biological reaction whereas • extractive bioprocessing almost entirely involves bioseparation. • In the context of reactive bioprocessing, upstream processing involves steps such as biocatalyst screening, enrichment, isolati ...
to view PDF - Hofstra People
to view PDF - Hofstra People

... A second set of genes that function in pseudohyphal growth are bud site selection and polarity genes. A dominant gain-offunction allele of RSR1/BUD1, a general bud site selection gene required for proper budding pattern in both haploid and diploid cells (Bender and Pringle, 1989; Chant and Herskowit ...
Evidence that the transport of ricin to the cytoplasm is independent
Evidence that the transport of ricin to the cytoplasm is independent

... Cells were transfected with expression plasmids encoding either wildtype Rab6A or mutant Rab6A (Rab6A-T27N) using LipofectAMINE 2000 (Life Technologies, Inc., Rockville, MD, USA) following the protocol provided by the vendor. In brief, cells were plated in 24-well plates at a density of 2×105 cells ...
Roles of vaccinia virus EEV-specific proteins in intracellular actin tail
Roles of vaccinia virus EEV-specific proteins in intracellular actin tail

... host cell that determines if actin tails are formed. However, it was noticeable that the number of actin tails varied with cell type and HeLa cells produced appreciably more intracellular actin tails than BS-C-1 cells (compare Fig. 1 a and 1 d and Fig. 2 a with Fig. 3 a and 3 b). It was possible tha ...
mrsa
mrsa

... NATIONAL CENTER FOR CASE STUDY TEACHING IN SCIENCE The PBP takes amino acid residues attached to peptidoglycan layers and forms bridges between them within the active site groove. This cross-linking, or cross-bridging, stabilizes and strengthens the cell wall. -lactam antibiotics interfere with th ...
Gene Therapy for Lung Cancer
Gene Therapy for Lung Cancer

... been unable to provide sufficient levels of gene product over long enough periods of time. Accordingly, most current gene therapy trials are aimed at acquired diseases (such as cancer) in which long-term gene expression is not necessarily required. Recent advances in the understand¬ ing of growth fa ...
Physical entity OPB - UW-SIG Publications
Physical entity OPB - UW-SIG Publications

... metabolism, gene expression, cell signaling… transmembrane potential, action potential… intracellular calcium dynamics… body temperature regulation… ...
CRAYFISH DISSECTION LAB I
CRAYFISH DISSECTION LAB I

... INTRODUCTION: If numbers alone are used as a measure of success, arthropods are the most successful animals on Earth. Their adaptations are more specialized, allowing them to survive in many areas. Sense organs, such as eyes and antennae, muscles arranged in groups, jointed legs, and a protective bo ...
39 | the respiratory system
39 | the respiratory system

... By the end of this section, you will be able to: • Describe the passage of air from the outside environment to the lungs • Explain how the lungs are protected from particulate matter The primary function of the respiratory system is to deliver oxygen to the cells of the body’s tissues and remove car ...
Ontogeny of erythropoiesis
Ontogeny of erythropoiesis

... circulating primitive erythroblasts express several adhesion molecules that could mediate interactions with other cell types [19]. Coincident with primitive erythroblast enucleation, the appearance of a transient population of very small, nucleated cells with a rim of ey-globin-positive cytoplasm wa ...
Nerve activates contraction
Nerve activates contraction

... Relationship between Anatomy and Physiology  Structure determines what functions can occur  If structure changes, the function must also change ...
Systemic Sclerosis (Scleroderma)
Systemic Sclerosis (Scleroderma)

... - PG F, thromboxane A2 release - vasoconstriction & growth of endothelial cell and fibroblast - narrowing or obliteration, increased permeability 2. Fibrosis - aberrant regulation of fibroblast cell growth - increased production of extracellular matrix (collagen, fibronectin, and glycosaminoglycan) ...
Down-Regulation of DNA Topoisomerase IIα Leads to Prolonged
Down-Regulation of DNA Topoisomerase IIα Leads to Prolonged

... showed that paclitaxel (Taxol) influenced the expression of several cell cycle regulators. In particular, after 24-h drug treatment, the cyclin-dependent kinase inhibitor p21waf1/cip1/sdi1 (CDKN1A) was up-regulated, as was another Cdk1 modulator, 14-3-3␴. In contrast, Cdk1 (also known as cdc2 or p34 ...
Section 1 - WordPress.com
Section 1 - WordPress.com

... Content ...
< 1 ... 276 277 278 279 280 281 282 283 284 ... 1638 >

Organ-on-a-chip

An organ-on-a-chip (OC) is a multi-channel 3-D microfluidic cell culture chip that simulates the activities, mechanics and physiological response of entire organs and organ systems. It constitutes the subject matter of significant biomedical engineering research, more precisely in bio-MEMS. The convergence of labs-on-chips (LOCs) and cell biology has permitted the study of human physiology in an organ-specific context, introducing a novel model of in vitro multicellular human organisms. One day, they will perhaps abolish the need for animals in drug development and toxin testing.Although multiple publications claim to have translated organ functions onto this interface, the movement towards this microfluidic application is still in its infancy. Organs-on-chips will vary in design and approach between different researchers. As such, validation and optimization of these systems will likely be a long process. Organs that have been simulated by microfluidic devices include the heart, the lung, kidney, artery, bone, cartilage, skin and more.Nevertheless, building valid artificial organs requires not only a precise cellular manipulation, but a detailed understanding of the human body’s fundamental intricate response to any event. A common concern with organs-on-chips lies in the isolation of organs during testing. ""If you don’t use as close to the total physiological system that you can, you’re likely to run into troubles"" says William Haseltine, founder of Rockville, Maryland. Microfabrication, microelectronics and microfluidics offer the prospect of modeling sophisticated in vitro physiological responses under accurately simulated conditions.
  • studyres.com © 2026
  • DMCA
  • Privacy
  • Terms
  • Report