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Human Body Systems Technology Project
Human Body Systems Technology Project

... hard and dense, but not solid. Small canals run through the compact bone, carrying blood vessels and nerves from the bone’s surface to the living cells within the bone. Just inside the compact bone is a layer of spongy bone, which has many small spaces within it. ...
2010 - Department of Biology
2010 - Department of Biology

... queen of ants (here Acromyrmex). Queen reproductive organs contain two ovaries, each formed by several ovarioles connected to the uterus by oviducts. Note the presence of a prominent spermatheca, which is usually swollen in mated queens. (g,h) Focus on one ovariole captured by light microscopy (g) o ...
Hydrocortisone perturbs the cell proliferation pattern during feather
Hydrocortisone perturbs the cell proliferation pattern during feather

... seemed to have stopped morphogenesis. Compared to E 6.5 controls, no additional rows of placodes were seen in whole-mounts of epidermis (Fig. 3E), and the number of BrdU-incorporating nuclei decreased in the interplumar areas (compare Rg. 3F and Rg. 3B-D). Serial longitudinal sections showed that mo ...
gas exchange
gas exchange

... 22.12 CONNECTION: The human fetus exchanges gases with the mother’s blood  A human fetus does not breathe with its lungs. Instead, it exchanges gases with maternal blood in the placenta.  In the placenta, capillaries of maternal blood and fetal blood run next to each other. The fetus and mother d ...
SChapter27
SChapter27

... -Kidney’s will increase the rate of H+ secretion into tubular fluid, but cannot alone return the pH to normal until the underlying respiratory or circulatory problems are corrected. -Artificial respiration, mechanical ventilator, or induced bronchodilation can be used to increase pulmonary exchange. ...
Gas Exchange
Gas Exchange

... 22.12 CONNECTION: The human fetus exchanges gases with the mother’s blood  A human fetus does not breathe with its lungs. Instead, it exchanges gases with maternal blood in the placenta.  In the placenta, capillaries of maternal blood and fetal blood run next to each other. The fetus and mother d ...
Tests on urine provide information and clues to many diseases, and
Tests on urine provide information and clues to many diseases, and

... (called casts) to form in tiny tubes in the kidneys. The casts can then get flushed out into the urine. Casts can be made of different types of material, such as red or white blood cells, waxy or fatty substances, or protein. The type of cast can provide clues about the type of kidney disease that m ...
Ploidy of Bacillus subtilis exfusants: the haploid nature of cells
Ploidy of Bacillus subtilis exfusants: the haploid nature of cells

... experimentswith mixtures of whole parental cells confirm that biparental colonies are indeed mixed colonieswhich arise either by stickingof parental cells or through coincidence,i.e. their plating within a distance of about 0.4 mm. The previously reported experimental results can be accounted for in ...
Anatomy and Physiology Curriculum Outline
Anatomy and Physiology Curriculum Outline

... 3. Demonstrate competency using tools of measurement, microscopes, and computers. 4. Demonstrate proficiency in presenting results using measurable data, technology and mathematics. 5. Show complete familiarity with and observation of established safety practices. 6. Identify the hierarchical levels ...
AQA GCSE (9-1)
AQA GCSE (9-1)

...  Cells and related topics are all abstract concepts and are hard to visualise. The use of cell models may help some students to make and see connections between different types of cells. Students often believe that cells are inactive, two dimensional structures and the use of videos and electron mi ...
Wk 12 Lec 2 notes Resp 1 2015
Wk 12 Lec 2 notes Resp 1 2015

... Bronchitis Inflammation of bronchial walls Causes constriction and breathing difficulty The Bronchioles Each tertiary bronchus branches into multiple bronchioles which then branch into terminal bronchioles One tertiary bronchus forms about 6500 terminal bronchioles. Bronchioles have no cartilage are ...
Bell Work: What is the fundamental unit of life?
Bell Work: What is the fundamental unit of life?

... Peroxisomes are specialized metabolic compartments bounded by a single membrane Peroxisomes produce hydrogen peroxide and convert it to water Peroxisomes perform reactions with many different functions How peroxisomes are related to other organelles is still unknown ...
ST120 Respiratory System
ST120 Respiratory System

... Pleural Cavity Pleura = covers the outer surface of lungs and the lining of the inner surface of the rib cage  Parietal pleura lines the walls of the ...
Identification of fat-cell enhancer regions in Drosophila melanogaster
Identification of fat-cell enhancer regions in Drosophila melanogaster

... mesoderm. In Drosophila, pair-rule genes such as evenskipped help to establish intrinsic differences between mesodermal cells in a metameric pattern along the anterior– posterior axis (Azpiazu et al., 1996), while along the dorsal–ventral axis, decapentaplegic (dpp) expression in the dorsal embryoni ...
PD-1 promotes immune exhaustion by inducing antiviral T cell
PD-1 promotes immune exhaustion by inducing antiviral T cell

... diverge at day 7 with only CL13 capable of inducing T cell exhaustion and establishing persistence. Day 7 was chosen for analysis because antiviral T cells already show early signs of immune exhaustion (e.g., reductions in cytokine production and cytolytic activity) at this time point (Ahmed and Old ...
Respiratory System Review
Respiratory System Review

... trachea are the bronchi 2. The dome shaped muscle below the chest cavity is called the diaphragm 3. During swallowing, the air passage of the pharynx is covered by the epiglottis 4. Alveoli in the lungs are connected to the bronchi by a network of tiny tubes called bronchioles 5. Breathing is contro ...
Redistribution and differential extraction of soluble proteins in
Redistribution and differential extraction of soluble proteins in

... antibody and the non-specific binding of the fluorescently labeled secondary antibody to cellular components. However, an important, but generally unstated, assumption made in all immunofluorescence studies is that the permeabilization and fixation conditions used to prepare the cells for antibody a ...
(PTH).
(PTH).

... Unlike parathyroid hormone and vitamin D, calcitonin plays no role in normal day-to-day regulation of plasma Ca regulation in humans Calcitonin is used in acute treatment of hypercalcemia, alternative of estrogen for treating osteoporosis in women; treat Paget disease (localized regions of bone reso ...
The Tensegrity-Truss as a Model for Spine Mechanics: Biotensegrity
The Tensegrity-Truss as a Model for Spine Mechanics: Biotensegrity

... or less dense and weaker, non-linearly. If it were a fluid-filled pump, it would push the fluid out more forcefully as it emptied because the internal pressure rises as the icosahedron compresses. The non-linearity also occurs when the load is released and allows for a soft landing, shock absorber e ...
Immunity Hemopoiesis and Cellular Drosophila
Immunity Hemopoiesis and Cellular Drosophila

... its expression is necessary for cell maintenance during development (12, 13). The Drosophila genome encodes three RUNX transcription factors, of which Lozenge (Lz) is involved in hemopoiesis. Initially, it was observed that in a lozenge (lz) lossof-function mutant no crystal cells are formed (11). L ...
Cell-cycle regulation
Cell-cycle regulation

... 2. The paradigm of cell-cycle control The collective results from studies in various eukaryotes have demonstrated that progression through the cell-division cycle is driven by activation and inactivation of cyclin-dependent kinases (CDKs), which trigger the transition to subsequent phases of the cyc ...
Coombes JL, Han SJ, van Rooijen N, Raulet DH, Robey EA. 2012. Infection-induced regulation of natural killer cells by macrophages and collagen at the lymph node subcapsular sinus. Cell rep 2(1):124-135.
Coombes JL, Han SJ, van Rooijen N, Raulet DH, Robey EA. 2012. Infection-induced regulation of natural killer cells by macrophages and collagen at the lymph node subcapsular sinus. Cell rep 2(1):124-135.

... with an immobile structure in the lymph node. Indeed, we observed that a substantial fraction of the slow-moving NK cells closely associated with second harmonic signals indicative of collagen fibers (Figure 3A; Movie S2). Antibody staining of lymph node tissue sections confirmed that these structur ...
Culturability of Mycobacterium tuberculosis cells isolated from
Culturability of Mycobacterium tuberculosis cells isolated from

... been published about the e¡ect of persistence within the macrophage environment on bacterial viability. In one of these reports [19] measurements were made of both total count and viable count (CFU) of M. tuberculosis within human monocyte-derived macrophages 6 days post-infection. Inspection of the ...
Chapter_01
Chapter_01

... Golgi apparatus or Golgi complex are critical for post-translational modifications that help sort, condense, package, and deliver proteins arriving from the ER. Copyright © 2014 by Mosby, an imprint of Elsevier Inc. ...
Modelling lava flows by Cellular Nonlinear Networks (CNN
Modelling lava flows by Cellular Nonlinear Networks (CNN

... is the possibility to amplify a small local phenomenon carrying all the system in a new state. The velocity of lava flowing in a channel depends on the physical properties of the lava (density, viscosity, yield strength), environmental factors (gravity, underlying topography), and the channel dimens ...
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Organ-on-a-chip

An organ-on-a-chip (OC) is a multi-channel 3-D microfluidic cell culture chip that simulates the activities, mechanics and physiological response of entire organs and organ systems. It constitutes the subject matter of significant biomedical engineering research, more precisely in bio-MEMS. The convergence of labs-on-chips (LOCs) and cell biology has permitted the study of human physiology in an organ-specific context, introducing a novel model of in vitro multicellular human organisms. One day, they will perhaps abolish the need for animals in drug development and toxin testing.Although multiple publications claim to have translated organ functions onto this interface, the movement towards this microfluidic application is still in its infancy. Organs-on-chips will vary in design and approach between different researchers. As such, validation and optimization of these systems will likely be a long process. Organs that have been simulated by microfluidic devices include the heart, the lung, kidney, artery, bone, cartilage, skin and more.Nevertheless, building valid artificial organs requires not only a precise cellular manipulation, but a detailed understanding of the human body’s fundamental intricate response to any event. A common concern with organs-on-chips lies in the isolation of organs during testing. ""If you don’t use as close to the total physiological system that you can, you’re likely to run into troubles"" says William Haseltine, founder of Rockville, Maryland. Microfabrication, microelectronics and microfluidics offer the prospect of modeling sophisticated in vitro physiological responses under accurately simulated conditions.
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