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... completely the epithelial response to the hormone. This fact is noteworthy in the evaluation of the developmental significance and specificity levels of tissue interactions in developing lungs (Wessells, 1970), since it now seems likely that mesenchymal 'information' is required for the maintenance ...
Identification of the Sites of Asparagine
Identification of the Sites of Asparagine

... There are six potential N-linked glycosylation sites (the consensus sequence is Asn-Xaa-Ser/Thr for glycosylation on an asparagine residue, where Xaa is any amino acid except Pro) (Kornfeld and Kornfeld, 1985) at amino acid positions Asn-77, -99, -113, -177, -198, and -302 of human TSHR ectodomain ( ...
The goal of IndoorGML is to represent and allow for exchange of
The goal of IndoorGML is to represent and allow for exchange of

... Complex structures allow for a powerful mechanism to address the most diverse routing requirements. It covers many different application areas from simple indoor navigation or indoor geo-portal services, to emergency responses (not only in a building but also in a cruise ship), robot tracking and na ...
Context-Dependent Synaptic Action of Glycinergic and GABAergic
Context-Dependent Synaptic Action of Glycinergic and GABAergic

... Neuramin, Essex, UK) was applied exogenously with pressure pulses delivered through a picrospritzer (General Valve, Fairfield, NJ) via glass pipettes, the outer tip diameters of which ranged from 9 to 18 pm. The duration of pulses ranged from 3 to 800 msec at 15 psi. Glycine solutions were either 10 ...
Cadmium-Telluride-Solar-Cells
Cadmium-Telluride-Solar-Cells

... with junction quality, with properties of CdTe and with contacting have not been as successful. Improved doping of CdTe and increased understanding of key processing steps (e.g., cadmium chloride recrystallization and contacting) are key to improving cell efficiency. Since CdTe has the optimal band ...
Frog Body Parts and Functions - chatham
Frog Body Parts and Functions - chatham

... lower eyelid that moves over the eye to clean it and protect it. • Cloacal Opening - Opening of cloaca through which undigested food, urine, eggs, and sperm are passed. • Vocal Sacs - The vocal sac is the flexible membrane of skin possessed by most male frogs. The purpose of the vocal sac is usually ...
Frog Body Parts and Functions
Frog Body Parts and Functions

... lower eyelid that moves over the eye to clean it and protect it. • Cloacal Opening - Opening of cloaca through which undigested food, urine, eggs, and sperm are passed. • Vocal Sacs - The vocal sac is the flexible membrane of skin possessed by most male frogs. The purpose of the vocal sac is usually ...
Free PDF
Free PDF

... is able to lead to tolerance toward existing alloreactive CD4+ T cells in the periphery through anergy (followed by deletion) of these cells, due to the presentation of donor antigens on APCs in the absence of an activation signal. Focusing our attention on T1D among all the autoimmune diseases, th ...
Tolerance to mutations in the foot-and
Tolerance to mutations in the foot-and

... The high potential of FMDV for variation and adaptation may lead to modifications affecting receptor usage, tropism and antigenic diversity (Domingo et al., 2003; Jackson et al., 2003; Mason et al., 2003; Ruiz-Jarabo et al., 2004). Adaptation of FMDV to cell culture can result in selection of varian ...
Distribution of technetium-99m-labelled QVAR delivered using an Autohaler device in children
Distribution of technetium-99m-labelled QVAR delivered using an Autohaler device in children

... Use of the QVARTM formulation has been shown to significantly increase lung deposition in adults compared to other pMDI formulations, when delivered by either pMDI [6] or AutohalerTM [7, 8]. Clinical efficacy studies have also shown that 2.5-times more CFC/BDP is required to achieve the same benefic ...
Nuclear Factor of Activated T Cells - JEM
Nuclear Factor of Activated T Cells - JEM

... cotransfected 293T cells with HA-p300 and either fulllength NFAT1 or NFAT1DReg, which lacks aa 146–398 encoding the bulk of the regulatory domain. Immunoprecipitation of stimulated cell lysates with anti-HA followed by Western analysis revealed that NFAT1DReg was still capable of interaction with p3 ...
1 - AState.edu
1 - AState.edu

... • The importance of lysosomes to cell function and human health is made clear by hereditary disorders called lysosomal storage diseases. • A person with such a disease • is missing one or more of the digestive enzymes normally found within lysosomes and ...
Mechanism of Induction: Induced Pluripotent Stem Cells (iPSCs)
Mechanism of Induction: Induced Pluripotent Stem Cells (iPSCs)

... are used in reprogramming. For lowering the risk of chromosomal aberration in host cells, non integrating methods are used. Adenovirus, Sendai virus, polycistronic mini circle vectors and autonomous episomes have been studied but are reported to be less efficient. Dox lentiviral system and single po ...
Ultrastructural and Physiological Characterization of YELP, a Novel
Ultrastructural and Physiological Characterization of YELP, a Novel

... protein transport into the chloroplast [4], and alterations in chloroplast biogenesis and differentiation [5]. Additionally, mutations in mitochondria are also conducive to altered chlorophyll accumulation patterns and function. Differentiating mutants affected in chlorophyll biosynthesis from those ...
for ICD-10
for ICD-10

... to accumulate, leading to such secondary infections as sinusitis or bronchitis. The basal cells are small, nearly cuboidal cells thought to have some ability to differentiate into other cell types found within the epithelium. Cell differentiation happens when a cell divides and becomes more speciali ...
The role of lymphatics in renal inflammation
The role of lymphatics in renal inflammation

... *Both authors contributed equally to this work. ...
Slide 1
Slide 1

...  Osmosis: A Special Case of Diffusion  Osmosis is the movement of water through aquaporins  More solute molecules, lower concentration of water molecules  Water molecules diffuse across membrane toward solution with more solutes ...
The anammoxosome: an intracytoplasmic compartment in anammox
The anammoxosome: an intracytoplasmic compartment in anammox

Achieving CNS axon regeneration by manipulating convergent
Achieving CNS axon regeneration by manipulating convergent

... Integrins are transmembrane heterodimeric receptors that facilitate bidirectional signaling between cells and the extracellular environment, most notably proteins found in the ECM or on other cells (e.g., laminin, fibronectin). Integrin binding activates intracellular signaling cascades that affect ...
The different shapes of cocci
The different shapes of cocci

... debated (Tiyanont et al., 2006) and although the key effectors of cell wall biosynthesis controlled by MreBs have not yet been identified. A second cytoskeleton element is composed of the tubulin homologue FtsZ, which polymerizes as a ring at the division site and is widely distributed in bacteria ( ...
Arterial-venous endothelial plasticity
Arterial-venous endothelial plasticity

... resulted in excess capillary and blood vessel formation and hemorrhaging in the embryo, contributing to embryonic lethality (Kitsukawa et al., 1995). Production of a NRP1 null mutant by homologous recombination of the NRP1 gene induced disorganization of nerve pathways (Kitsukawa et al., 1997) and a ...
Word File
Word File

... capillaries. There it attaches onto the red blood cells and is carried to all body cells. Carbon dioxide takes the opposite journey, moving out of the body's cells to the red blood cells, and then through the capillary and alveoli walls into the alveoli so it can be breathed out. ...
Role for a bidentate ribonuclease in the initiation step of RNA
Role for a bidentate ribonuclease in the initiation step of RNA

... than one mechanism. Our results indicate that the process of RNAi can be divided into at least two distinct steps. Initiation of PTGS would occur on processing of a dsRNA by Dicer into ,22-nucleotide guide sequences, although we cannot formally exclude the possibility that another Dicer-associated n ...
the potato skin and skin set
the potato skin and skin set

... silvering and separation of the cell layers, thus causing the skin to slip-off very easily, even after the tubers were allowed to set skin. If tubers are left in the field for prolonged periods, the pathogens will continue to grow on the skin and cause large blemishes that may result in down grading ...
Column Flotation
Column Flotation

... and scavenging. However the main purpose of the column cell is to improve the final concentrate grade to a level that would not be possible using only conventional flotation. In many cases, the use of column flotation enables a concentrate to achieve separation that is closer to perfect than any oth ...
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Organ-on-a-chip

An organ-on-a-chip (OC) is a multi-channel 3-D microfluidic cell culture chip that simulates the activities, mechanics and physiological response of entire organs and organ systems. It constitutes the subject matter of significant biomedical engineering research, more precisely in bio-MEMS. The convergence of labs-on-chips (LOCs) and cell biology has permitted the study of human physiology in an organ-specific context, introducing a novel model of in vitro multicellular human organisms. One day, they will perhaps abolish the need for animals in drug development and toxin testing.Although multiple publications claim to have translated organ functions onto this interface, the movement towards this microfluidic application is still in its infancy. Organs-on-chips will vary in design and approach between different researchers. As such, validation and optimization of these systems will likely be a long process. Organs that have been simulated by microfluidic devices include the heart, the lung, kidney, artery, bone, cartilage, skin and more.Nevertheless, building valid artificial organs requires not only a precise cellular manipulation, but a detailed understanding of the human body’s fundamental intricate response to any event. A common concern with organs-on-chips lies in the isolation of organs during testing. ""If you don’t use as close to the total physiological system that you can, you’re likely to run into troubles"" says William Haseltine, founder of Rockville, Maryland. Microfabrication, microelectronics and microfluidics offer the prospect of modeling sophisticated in vitro physiological responses under accurately simulated conditions.
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