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... ulcers); treat w/ G-CSF, usually improves after puberty o Congenital neutropenia – PMN maturation arrest; freq. infections, mouth sores, leukemia risk  Tx – give artificial G-CSF, bone marrow transplant (BMT) Neutrophil Function  Response Process – when tissue is damaged, chemotactic factors relea ...
1. The Nervous System - Classroom Complete Press
1. The Nervous System - Classroom Complete Press

... RESEARCH: Using the reading passages, and information from the library or the Internet, Now you’re ready to play your game! • What kinds of SENSATIONS can you feel with this sense? You have just been hired as a TRAVEL AGENT. You have been given the job find out how the respiratory system works. You ...
Animal Physiology
Animal Physiology

...  Don the stethoscope and position the diaphragm over the marked brachial area. (See fig c above). As you carry out this procedure remember that the cuff should not be kept highly inflated on the arm for more than about one minute. (Prolonged interruption of blood flow can cause fainting) If you hav ...
MHC antigeny
MHC antigeny

... Cross-presentation of antigen • MHC class I molecules are able to present exogenous peptides (cross-presentation) • Material recognised by cell surface receptors is endocyted, become a part of endosomes, where is partially (but not completely) degraded and transported into cytoplasm, where is cleav ...
pptx
pptx

... epithelia in response to a meal6. A previous study suggests an increase in GLUT2 translocation to the AP membrane of mouse jejunal tissue following metformin treatment due to the activation of the cellular energy sensor, AMP-activated protein kinase (Figure ...
9700/04 - StudyGuide.PK
9700/04 - StudyGuide.PK

... You may use a soft pencil for any diagrams, graphs or rough working. Do not use staples, paper clips, highlighters, glue or correction fluid. Answer all questions. The number of marks is given in brackets [ ] at the end of each question or part question. ...
Tissues
Tissues

... • An organ consists of two or more tissues packaged into one working unit that performs a specific function. • An organ performs functions that none of its component tissues can carry out alone. • Examples include the heart, brain, and small intestines. ...
Emergency Department Policy - Orange Health Service Emergency
Emergency Department Policy - Orange Health Service Emergency

... Arterial lines should be inserted in a clean area using full aseptic technique (gowns, sterile gloves, drapes, skin prep etc). 4.5 Use of bedside US Ultrasound guidance can improve the success rate for arterial line insertion. 4.6 Indications The indications for a radial arterial line are: 1. Contin ...
The Cell Membrane - Libreria Universo
The Cell Membrane - Libreria Universo

... movements. Rather, a ping-pong mechanism has been proposed (Fig. 2.5A). In this model, the carrier protein exists in two principal conformations: ping and pong. In the pong state, it is exposed to high concentrations of solute, and the moleTransport occurs when a conformational change to the ping st ...
Relationship between the timing of DNA replication and the
Relationship between the timing of DNA replication and the

... rate of increase of FITC-labelled cohort per labelling time is lower in D cells than in ND cells. Second, in D cells, especially after a prolonged period of BrdUrd/ FdUrd labelling, FITC fluorescence is found in a first small cohort, in a second major cohort and in a third smaller population. In ND ...
STRUCTURE OF SYNAPSES: OVERVIEW
STRUCTURE OF SYNAPSES: OVERVIEW

... neurotransmitters in the postsynaptic membrane. Thus synaptic transmission relies on the vesicle mediated exocytosis of neurotransmitter. There is usually only one small molecule transmitter for a specific neuron type, but examples of different transmitters being released from the same varicosity ha ...
Relative Abundance of Nickel in the Leaf
Relative Abundance of Nickel in the Leaf

... low voltage before it was slightly etched for a few seconds at ÿ908C, moved back to the cryo-preparation chamber and coated with gold. The specimens were examined at 20 kV. Dry leaves from the same species kept in the University of Patras Herbarium were examined for comparison. The dry plant materia ...
Functions of Skeletal Muscle Tissue
Functions of Skeletal Muscle Tissue

... an inherent rythmicity. That is, an auto-generated action potential that stimulates the cell's contraction. At the tissue level, cardiac muscle inherently exhibits the rhythmicity of the cardiac muscle cell with the fastest rhythmicity. Once the action potential is generated by this cell, the impuls ...
Powerpoint Presentation: Transport in Plants
Powerpoint Presentation: Transport in Plants

... the endodermis The cell walls of the endodermis are water proofed by a Casparian strip At the endodermis the plant can have control over what it absorbs ...
Virtual Dissection
Virtual Dissection

... cartilage that form the framework of the body  Muscular system-includes the muscles that help you move, and muscles that help things inside your body move  Digestive system-breaks down food into substances the body can use ...
Pseudomonas aeruginosa Exolysin promotes - HAL
Pseudomonas aeruginosa Exolysin promotes - HAL

... a bacteremia model, suggesting that it can be promptly phagocytosed by immune cells. Together, our study ascribes to ExlA-secreting bacteria the capacity to proliferate in the lung and to damage pulmonary tissues, thereby promoting metastatic infections, in absence of substantial immune response exa ...
RN.com’s Assessment Series: Focused Renal and Urinary Assessment
RN.com’s Assessment Series: Focused Renal and Urinary Assessment

... Bowman’s capsule: Part of the renal corpuscle. It consists of a visceral layer of podocytes closely applied to the glomerulus and an outer parietal layer. The podocyte layer is part of the filter for the formation of renal filtrate in the space between the two layers. Catabolism: The metabolic break ...
Immunological Memory: Contribution of Memory B Cells Expressing
Immunological Memory: Contribution of Memory B Cells Expressing

... representing the subset of recently activated memory B cells at any given point in time), then their frequency would increase gradually over time, as has been previously shown for CD27⫹ B cells (17). Indeed, the CD80⫹ B cell subset was essentially absent in cord blood (Fig. 1D), and its frequency in ...
Bacterial Age
Bacterial Age

... we really do not have a universal explanation for the bacterial aging. As a matter of fact, some people claim that bacteria as well as other unicellular microorganisms do not senescent (5) since they appear to be immortal due to their autonomous and continuous cell cycles (6). The newly proposed bac ...
Plant microtubule organization
Plant microtubule organization

... meeting at the midplane. They direct the transport of Golgiderived vesicles towards the centrifugally expanding cell plate, which matures to become the cross-wall separating daughter cells (Otegui and Staehelin, 2000a). Phragmoplast microtubules originate as a compact cylindrical bundle between the ...
Prescribing Information and Instructions for Use
Prescribing Information and Instructions for Use

... HEMACORD may transmit rare genetic diseases involving the hematopoietic system for which donor screening and/or testing has not been performed [see Adverse Reactions (6.1)]. Cord blood donors have been screened by family history to exclude inherited disorders of the blood and marrow. HEMACORD has be ...
Full-Text PDF
Full-Text PDF

... become contained within the lumen of that compartment (with example assembly sites including the endoplasmic reticulum, trans-Golgi network, and endosomes). The localization of cellular membrane proteins frequently involves discrete targeting motifs, short sequences present in cytoplasmic domains of ...
Digestive System
Digestive System

... Sperm travels from the vagina through the cervix and uterus and into the fallopian tubes ...
A Role for Mitochondria in the Establishment and
A Role for Mitochondria in the Establishment and

... (Fig. 1D). As in the QC, mitochondria in the PM encircle the nucleus (Fig. 1E). However, in contrast to QC mitochondria, PM mitochondria frequently assumed a dumbbell shape (in approximately two-thirds [eight] of the roots examined ultrastructurally), and this is interpreted as indicative of their c ...
Mechanisms of cell positioning during C. elegans gastrulation
Mechanisms of cell positioning during C. elegans gastrulation

... Priess, 2002), but their functional requirements have not been tested. Therefore, it is currently unclear what mechanisms control this important event. In this study, we first asked if we could extend the C. elegans in vitro system to study morphogenetic movements during gastrulation. We also addres ...
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Organ-on-a-chip

An organ-on-a-chip (OC) is a multi-channel 3-D microfluidic cell culture chip that simulates the activities, mechanics and physiological response of entire organs and organ systems. It constitutes the subject matter of significant biomedical engineering research, more precisely in bio-MEMS. The convergence of labs-on-chips (LOCs) and cell biology has permitted the study of human physiology in an organ-specific context, introducing a novel model of in vitro multicellular human organisms. One day, they will perhaps abolish the need for animals in drug development and toxin testing.Although multiple publications claim to have translated organ functions onto this interface, the movement towards this microfluidic application is still in its infancy. Organs-on-chips will vary in design and approach between different researchers. As such, validation and optimization of these systems will likely be a long process. Organs that have been simulated by microfluidic devices include the heart, the lung, kidney, artery, bone, cartilage, skin and more.Nevertheless, building valid artificial organs requires not only a precise cellular manipulation, but a detailed understanding of the human body’s fundamental intricate response to any event. A common concern with organs-on-chips lies in the isolation of organs during testing. ""If you don’t use as close to the total physiological system that you can, you’re likely to run into troubles"" says William Haseltine, founder of Rockville, Maryland. Microfabrication, microelectronics and microfluidics offer the prospect of modeling sophisticated in vitro physiological responses under accurately simulated conditions.
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