• Study Resource
  • Explore Categories
    • Arts & Humanities
    • Business
    • Engineering & Technology
    • Foreign Language
    • History
    • Math
    • Science
    • Social Science

    Top subcategories

    • Advanced Math
    • Algebra
    • Basic Math
    • Calculus
    • Geometry
    • Linear Algebra
    • Pre-Algebra
    • Pre-Calculus
    • Statistics And Probability
    • Trigonometry
    • other →

    Top subcategories

    • Astronomy
    • Astrophysics
    • Biology
    • Chemistry
    • Earth Science
    • Environmental Science
    • Health Science
    • Physics
    • other →

    Top subcategories

    • Anthropology
    • Law
    • Political Science
    • Psychology
    • Sociology
    • other →

    Top subcategories

    • Accounting
    • Economics
    • Finance
    • Management
    • other →

    Top subcategories

    • Aerospace Engineering
    • Bioengineering
    • Chemical Engineering
    • Civil Engineering
    • Computer Science
    • Electrical Engineering
    • Industrial Engineering
    • Mechanical Engineering
    • Web Design
    • other →

    Top subcategories

    • Architecture
    • Communications
    • English
    • Gender Studies
    • Music
    • Performing Arts
    • Philosophy
    • Religious Studies
    • Writing
    • other →

    Top subcategories

    • Ancient History
    • European History
    • US History
    • World History
    • other →

    Top subcategories

    • Croatian
    • Czech
    • Finnish
    • Greek
    • Hindi
    • Japanese
    • Korean
    • Persian
    • Swedish
    • Turkish
    • other →
 
Profile Documents Logout
Upload
Therapies for sarcopenia and regeneration of old skeletal muscles
Therapies for sarcopenia and regeneration of old skeletal muscles

... In contrast, a series of complex studies using parabiosis to conjoin the blood supply of young (2–3 mo) and old (19–26 mo) C57Bl/6J mice, followed by freeze injury, in conjunction with extensive tissue culture studies,20,21 concluded that myogenic stem cell activity is significantly impaired in old ...
The Role of the Leukemia Inhibitory Factor (LIF)
The Role of the Leukemia Inhibitory Factor (LIF)

... the LIF/STAT3-pathway in vivo. However, studies on knockout mouse models indicate that at least the early embryonic development can occur also in the absence of some components of the LIF-pathway but many of these mouse models then display later on during development or during adulthood many differe ...
Biosynthesis and properties of the plant cell wall Wolf
Biosynthesis and properties of the plant cell wall Wolf

... XYLEM2 (IRX2) ([23,24•,25], S Turner, personal communication). This protein is primarily localized to the cell plate [26] but has also been found in plasma-membrane fractions [23]. Mutations in the KOR1 gene cause a decrease in cellulose formation [24•,25], which is partly compensated for by an incr ...
Induction of apoptosis by the Amsacta moorei entomopoxvirus
Induction of apoptosis by the Amsacta moorei entomopoxvirus

... or mitochondrial (intrinsic) pathways, which result in the activation of effector caspases. The active effector caspases, through cleavage of specific host proteins, are instrumental in directing subsequent morphological and biochemical changes associated with apoptosis. These changes include reduct ...
[PDF]
[PDF]

... which may be interpreted as an increase in synaptic area, consistent with a reduced ability to modify synapses with learning (O’Donnell and Warren, 2002). Similarly, in flies, dFmr1 mutations affect the neuromuscular junction (NMJ) by increasing the synaptic area (Schenck et al., 2003; Zhang et al., ...
A Triad of Costimulatory Molecules Synergize to
A Triad of Costimulatory Molecules Synergize to

... (15). In recombinant viruses containing a single foreign gene, the gene is under control of the vaccinia 40k promoter (16). rV-B7-1/ICAM-1 is a recombinant vaccinia virus that contains the murine B7-1 gene under control of the synthetic early/late (sE/L) promoter (17) and the murine ICAM-1 gene unde ...
Commentary on “Research on Mitotic Mechanisms”
Commentary on “Research on Mitotic Mechanisms”

... Mitosis is the process by which eukaryotic cells segregate their already duplicated chromosomes and move them to opposite ends of the cell in preparation for cell division. Its biological importance is seen in the facts that accurate chromosome segregation is essential for successful cell division a ...
Classifying Living Things
Classifying Living Things

... a. Usually exist as single cells; creatures move using short, hair-like structures called ‘cilia’ or finger-like projections of the cytoplasm called ‘psuedopods’ ……………………………………………………………….…………………………………. Go to 3 b. Organism feeds on bacteria and decaying organic matter; when food is plentiful, it form ...
cell-cycle progression and the generation of asymmetry in
cell-cycle progression and the generation of asymmetry in

... analysis of the cell cycle. Caulobacter has also emerged as a model system for understanding how bacteria establish and maintain cellular asymmetry. Each cell division in this organism produces two daughter cells that are morphologically and physiologically distinct (FIG. 1). Asymmetric cell divisio ...
Roles of ion channels and transporters in guard cell signal
Roles of ion channels and transporters in guard cell signal

... are dependent on its phosphorylation status [30], and the subunit AtKC1, which forms a heteromeric channel with KAT1 or AKT1 [31,32] are expressed in guard cells. Shaker channels in animals function as tetramers, and coassembly of different monomers can affect channel characteristics. Because the indi ...
Growth of Tyzzer`s Organism in Primary Monolayer
Growth of Tyzzer`s Organism in Primary Monolayer

... agar slopes. With chick embryo tissue, however, the results were not satisfactory. Craigie (1966) failed to infect a monolayer culture of the yolk sac endoderm from chick embryos, although some parasitized cells were seen when the culture was prepared from infected embryos. He attributed his failure ...
2811_Chapter4
2811_Chapter4

Adult stem cells and their ability to differentiate
Adult stem cells and their ability to differentiate

... Stem cells are classified according to their differentiation potential as totipotent, pluripotent, or multipotent. Totipotent stem cells are capable of forming any tissue in the body, similarly to a fertilized egg which, following cleavage, produces cells which differentiate into all types of tissues ...
Biophys-85_R1
Biophys-85_R1

... ~20 cm H2O) induced transient ATP release in a limited number of air-inflated alveolar sacs. Released ATP remained spatially restricted to single alveolar sacs or their clusters. With L-L introduced into blood vessels, inflation induced transient ATP release, which occurred in small patch-like areas ...
Expression of Recombinant Myelin
Expression of Recombinant Myelin

... cells is regulated by axonal interaction (26). Schwann cells maintained in the absence of neurons do not express MAG; however, MAG is detectable after 7 d of co-culture with sensory neurons. Neuronal induction of MAG expression can occur before the onset of myelination and does not require assembly ...
Biology High School Release Item Document MCAS 2014
Biology High School Release Item Document MCAS 2014

... • Show all your work (diagrams, tables, or computations) in your Student Answer Booklet. • If you do the work in your head, explain in writing how you did the work. Write your answer to question 12 in the space provided in your Student Answer Booklet. ...
machen2006
machen2006

... hyperinflammatory phenotypes. In contrast to these studies showing apparent intrinsic hyperinflammation in CF cells, Dakin et al. (32) showed that early infection in CF was the likely explanation for the enhanced inflammatory responses in CF lungs. This result was consistent with other in vivo measu ...
Meiosis/Mitosis Webquest
Meiosis/Mitosis Webquest

... many times as necessary to answer questions & summarize the first stage of meiosis. 1. At the start of this example how many chromosomes are in the cell? 2. What happens in the “S” phase to the chromosomes? 3. If a chromosome replicates but remains attached does it count as one or two chromosomes? 4 ...
Reading Part 2: The Respiratory System
Reading Part 2: The Respiratory System

... ribs to increase thoracic volume even more. ...
hemoglobinopathies - Turner White Communications
hemoglobinopathies - Turner White Communications

... into chains, or microfibrils, that stiffen the red cells and stretch them into the classic sickle shape. In this process, the membranes become permeable to water and potassium, resulting in cellular dehydration. The deranged membranes also interact with adhesion molecules in the plasma, making the s ...
Mosaic Genetic Screen for Suppressors of the de2f1 Mutant
Mosaic Genetic Screen for Suppressors of the de2f1 Mutant

... The growth suppressive function of the retinoblastoma (pRB) tumor suppressor family is largely attributed to its ability to negatively regulate the family of E2F transcriptional factors and, as a result, to repress E2F-dependent transcription. Deregulation of the pRB pathway is thought to be an obli ...
TOPIC OUTLINE I. Introduction A. Renal Function B. The Nephron II
TOPIC OUTLINE I. Introduction A. Renal Function B. The Nephron II

... o 120 AAs, single pp. chain Cysteine-protease inhibitor Stable production rate by most nucleated cells Freely filtered at glomerulus Reabsorbed/ catabolized in the proximal tubule Immunoturbidimetric / nepholometric particle-enhanced assays Interference from turbidity and rheumatoid factors Stable r ...
Every Food and Health Answer
Every Food and Health Answer

... (different antibodies) have different amino acid sequence; (different antibodies) have different shape; (different antibodies) fit different antigens; ref. to specificity/complementary; A lock and key ...
AB Balance Lecture 1_2015
AB Balance Lecture 1_2015

... about twice the concentration and contains about three times the number of histidine residues per molecule. For example if blood pH changed from 7.5 to 6.5, haemoglobin would buffer 27.5 mmol/l of H+ and total plasma protein buffering would account for only 4.2 mmol/l of H+. ...
The lazy Detox - johnerdman.com - Allow the doctor within to heal
The lazy Detox - johnerdman.com - Allow the doctor within to heal

... 2) Are you more than 10 pounds over weight? 3) Are you tired and sluggish? 4) Do you have food allergies? 5) Do you crave breads or sugary sweets? 6) Do you rarely exercise? 7) Does your skin breakout? 8) Do you have bad breath? 9) Do you have to mask body odor with a scent? 10) Never done an inner ...
< 1 ... 212 213 214 215 216 217 218 219 220 ... 1638 >

Organ-on-a-chip

An organ-on-a-chip (OC) is a multi-channel 3-D microfluidic cell culture chip that simulates the activities, mechanics and physiological response of entire organs and organ systems. It constitutes the subject matter of significant biomedical engineering research, more precisely in bio-MEMS. The convergence of labs-on-chips (LOCs) and cell biology has permitted the study of human physiology in an organ-specific context, introducing a novel model of in vitro multicellular human organisms. One day, they will perhaps abolish the need for animals in drug development and toxin testing.Although multiple publications claim to have translated organ functions onto this interface, the movement towards this microfluidic application is still in its infancy. Organs-on-chips will vary in design and approach between different researchers. As such, validation and optimization of these systems will likely be a long process. Organs that have been simulated by microfluidic devices include the heart, the lung, kidney, artery, bone, cartilage, skin and more.Nevertheless, building valid artificial organs requires not only a precise cellular manipulation, but a detailed understanding of the human body’s fundamental intricate response to any event. A common concern with organs-on-chips lies in the isolation of organs during testing. ""If you don’t use as close to the total physiological system that you can, you’re likely to run into troubles"" says William Haseltine, founder of Rockville, Maryland. Microfabrication, microelectronics and microfluidics offer the prospect of modeling sophisticated in vitro physiological responses under accurately simulated conditions.
  • studyres.com © 2026
  • DMCA
  • Privacy
  • Terms
  • Report