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WATCHMAN™ Access Sheath
WATCHMAN™ Access Sheath

... • If using a power injector, the maximum pressure should not exceed 100 psi. • In view of the concerns that were raised by the RE-ALIGN1 study of dabigatran in the presence of prosthetic mechanical heart valves, caution should be used when prescribing oral anticoagulants other than warfarin in patie ...
Metabolomics of a single vacuole reveals metabolic dynamism in an
Metabolomics of a single vacuole reveals metabolic dynamism in an

... Coenzymes, UDP-sugars, and sugar phosphates, whose levels could be regulated by cytoplasmic homeostasis, were classified in cluster 1 (red). Cluster 2 (orange) consisted of various metabolites that were detected in minute amounts. Although these metabolites did not show a set pattern in their ...
At the border: the plasma membrane–cell wall
At the border: the plasma membrane–cell wall

... Various data support the role of cellulose fibres in plasma membrane–cell wall adhesion (reviewed in Cvřcková, 2013; Martinière and Runions, 2013). Interestingly, cellulose has recently been shown to restrict plasma membrane protein diffusion, which may explain the slow diffusion of plant plasma mem ...
GSK-3 Promotes Cell Survival, Growth, and PAX3 Levels in Human
GSK-3 Promotes Cell Survival, Growth, and PAX3 Levels in Human

... phosphorylation and increased levels of PAX3. Mol Cancer Res; 10(8); 1065–76. 2012 AACR. ...
T cell metabolism drives immunity
T cell metabolism drives immunity

... gun, pathogen-derived or inflammatory signals drive T cells out of quiescence, resulting in rapid modulation of gene expression and the acquisition of new functions.These changes range from increased production of cytokines and cytolytic molecules to the ability to undergo cell division and migratio ...
Rab-A2 and Rab-A3 GTPases Define a trans
Rab-A2 and Rab-A3 GTPases Define a trans

... subclass (RAB-A2a, -A2b, -A2c, and -A2d) and with the single Rab-A3 protein (RAB-A3). These DNA fragments included the entire intergenic region with additional upstream sequences in some instances (see Supplemental Figure 1 online). Fluorescence microscopy of transgenic plants (see Supplemental Figu ...
Stage-Specific Histone Modification Profiles Reveal Global
Stage-Specific Histone Modification Profiles Reveal Global

... Our knowledge about the epigenetic changes, which accompany the determination of definitive somatic cell lineages in the mammalian embryo, are derived largely from in vitro differenti- ...
Protist Worksheet - hrsbstaff.ednet.ns.ca
Protist Worksheet - hrsbstaff.ednet.ns.ca

... Protists? The Kingdom Protista has become a “dumping ground” for organisms that don’t fit into the other three kingdoms. They are always eukaryotes, but after that just about anything goes. Protist classification is still in such flux that many of the group names are just not worth learning. In fact ...
Frog Dissection
Frog Dissection

... 10. Cut the ABDOMINAL MUSCLES in half along the solid black line through the center. Place a small amount of glue along the outside of the legs along the dotted lines. Paste each half down on the frog, aligning it with the frog body. 11. Complete the same process ABOVE with the frog BELLY. Apply pas ...
Transcripts of the npm-alk fusion gene in anaplastic large cell
Transcripts of the npm-alk fusion gene in anaplastic large cell

... depleted HD, malignant histiocytosis, melanoma, or anaplastic carcinoma. Today, most misdiagnoses canbe avoided with the application of modem analytical techniques including immunohistochemistry, electron microscopy, and molecular analysis of T- and B-cell antigen receptor gene rearrangements. Howev ...
fulltext - DiVA Portal
fulltext - DiVA Portal

... levels and nature of the myriad of biomolecules present. Aberrantly regulated or damaged genes can cause pathological states due to disruption of various biological processes [1,2]. In some instances, these genetic aberrations are inherited insofar as they are present in the germline cells but in ot ...
ApexCal - Ivoclar Vivadent
ApexCal - Ivoclar Vivadent

... Direct pulp capping is indicated when a small part of a clinically healthy pulp (< 1mm2) is accidentally exposed in non-carious dentin during cavity preparation [2,3]. The application of a highly alkaline calcium hydroxide preparation on the exposed pulp rapidly causes superficial tissue necrosis to ...
PDF
PDF

... the molecular mechanics of mitosis over the past quarter of a century. As with all studies of mitosis, the principal findings have been rooted in observations made through microscopy; this is hardly surprising as mitosis is possibly the most spectacular event in a cell’s natural life cycle. The even ...
Human Body Systems - local
Human Body Systems - local

...  Estrous: in mammals like cats and dogs, no blood, when it happens the female is in heat, hormones controlled by ovaries, feedback controlled by steroids in the ovaries  Menstrual: in mammals like humans and some primates, monthly bleeding cycle, female can receive male at any time, hormones contr ...
Ultrastructure of the body cavities in phylactolaemata Bryozoa
Ultrastructure of the body cavities in phylactolaemata Bryozoa

... 1973, Brusca and Brusca 2003, Ruppert et al. 2004). Some authors regard the epistome coelom to be confluent with the lophophoral coelom (Ryland 1970, Mukai et al. 1997) Another unsolved issue is the mode of excretion in Bryozoa. Metanephridial organs drain primary urine out of the trunk coelom in Ph ...
FREE Sample Here
FREE Sample Here

... 1. A midsagittal plane vertically divides the body through the midline into two equal left and right portions or halves. ANS: T PTS: 1 NOT: A midsagittal plane vertically divides the body through the midline into two equal left and right portions. 2. A horizontal or transverse plane is any plane div ...
514 Interspinous Fixation (Fusion) Devices
514 Interspinous Fixation (Fusion) Devices

... 2. The scientific evidence must permit conclusions concerning the effect of the technology on health outcomes; 3. The technology must improve the net health outcome; 4. The technology must be as beneficial as any established alternatives; 5. The improvement must be attainable outside the investigati ...
The Mitotic Arrest in Response to Hypoxia and of Polar Bodies
The Mitotic Arrest in Response to Hypoxia and of Polar Bodies

... Mps11 therefore reflects a lack of Mps1 function. Moreover, EGFP-Mps1 is a functional protein. The relatively late stage of Mps11 lethality suggested that Mps1 is not absolutely essential for progression through the cell division cycle. However, phenotypic consequences in Mps11 homozygotes might als ...
The Cortical Microtubule Array: From Dynamics to
The Cortical Microtubule Array: From Dynamics to

... ters between randomly nucleated CMTs deterministically modify the stochastic behavior of CMTs so as to foster a parallel arrangement. Here, the principal challenge will be to determine the rules that govern the outcome of the intermicrotubule encounters and decide whether they contribute to self-org ...
FREE Sample Here
FREE Sample Here

... 1. A midsagittal plane vertically divides the body through the midline into two equal left and right portions or halves. ANS: T PTS: 1 NOT: A midsagittal plane vertically divides the body through the midline into two equal left and right portions. 2. A horizontal or transverse plane is any plane div ...
Microtubules Contribute to Tubule Elongation and
Microtubules Contribute to Tubule Elongation and

... The endoplasmic reticulum (ER) is a network of tubules and sheet-like structures in eukaryotic cells. Some ER tubules dynamically change their morphology, and others form stable structures. In plants, it has been thought that the ER tubule extension is driven by the actin-myosin machinery. Here, we ...
Diffusion
Diffusion

... through biologic membranes is an essential step for drugs entering (i.e., absorption) or leaving (i.e., elimination) the body. ...
PDF
PDF

... Douarin and Teillet, 1973) showed that the enteric nervous system (ENS) of the avian embryo arises from a specific axial level of the neural crest, and that the cells that originate from the neural crest appear to migrate a long distance to reach the gut wall. Although a neural crest origin of the E ...
Cunningham_etal_2012_Experimental
Cunningham_etal_2012_Experimental

... Figure 1. (a–h) Decay in the giant sulphur bacterium Thiomargarita namibiensis and (i–l ) comparison with Doushantuo microfossils. (a–d) Differential interference contrast (DIC) microscopy images of Thiomargarita. (a) Living Thiomargarita cell with diffuse sulphur vesicles surrounding the central va ...
Study of adhesive and invasion capacity of some opportunistic
Study of adhesive and invasion capacity of some opportunistic

... In vitro testing of the influence of anaerobic bacteria on adhesion and invasion capacity of E. coli strains was performed by using a modified Cravioto method (Cravioto, 1979). For each strain two 24 multiwell plates were used, one of them with circular coverslips of 13mm diameter (Chance Propper L ...
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Organ-on-a-chip

An organ-on-a-chip (OC) is a multi-channel 3-D microfluidic cell culture chip that simulates the activities, mechanics and physiological response of entire organs and organ systems. It constitutes the subject matter of significant biomedical engineering research, more precisely in bio-MEMS. The convergence of labs-on-chips (LOCs) and cell biology has permitted the study of human physiology in an organ-specific context, introducing a novel model of in vitro multicellular human organisms. One day, they will perhaps abolish the need for animals in drug development and toxin testing.Although multiple publications claim to have translated organ functions onto this interface, the movement towards this microfluidic application is still in its infancy. Organs-on-chips will vary in design and approach between different researchers. As such, validation and optimization of these systems will likely be a long process. Organs that have been simulated by microfluidic devices include the heart, the lung, kidney, artery, bone, cartilage, skin and more.Nevertheless, building valid artificial organs requires not only a precise cellular manipulation, but a detailed understanding of the human body’s fundamental intricate response to any event. A common concern with organs-on-chips lies in the isolation of organs during testing. ""If you don’t use as close to the total physiological system that you can, you’re likely to run into troubles"" says William Haseltine, founder of Rockville, Maryland. Microfabrication, microelectronics and microfluidics offer the prospect of modeling sophisticated in vitro physiological responses under accurately simulated conditions.
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