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... sodium currents either by an inhibitor of voltage-gated sodium channels or by antisense-mediated knockdown of an subunit of voltage-gated sodium channels (Nav1.6a) also decreases the RB cell death (Svoboda et al., 2001; Pineda et al., 2006), thereby suggesting that neurotrophic inputs, kinase regu ...
... sodium currents either by an inhibitor of voltage-gated sodium channels or by antisense-mediated knockdown of an subunit of voltage-gated sodium channels (Nav1.6a) also decreases the RB cell death (Svoboda et al., 2001; Pineda et al., 2006), thereby suggesting that neurotrophic inputs, kinase regu ...
An Entrapped Subclavian Stent and its Successful Management
... Subclavian artery stenosis is most commonly caused in atherosclerotic disease. Stenosis typically occurs in the first part of the subclavian artery. Intervention is generally reserved for the treatment of symptomatic patients. Symptoms may be attributable to upper extremity, cerebral, or coronary is ...
... Subclavian artery stenosis is most commonly caused in atherosclerotic disease. Stenosis typically occurs in the first part of the subclavian artery. Intervention is generally reserved for the treatment of symptomatic patients. Symptoms may be attributable to upper extremity, cerebral, or coronary is ...
Lymphatic vessels and tertiary lymphoid organs
... the response of these cells to neuronal signals, including retinoic acid (11). HEVs are also key organizers of LN development (12), in that they express LTβR (13), respond to LTαβ (14, 15), and present chemokines and adhesion molecules Functions of LVs in SLOs Afferent LVs bring antigen and APCs to ...
... the response of these cells to neuronal signals, including retinoic acid (11). HEVs are also key organizers of LN development (12), in that they express LTβR (13), respond to LTαβ (14, 15), and present chemokines and adhesion molecules Functions of LVs in SLOs Afferent LVs bring antigen and APCs to ...
Towards a Small Emittance Design of the JLEIC Electron Collider Ring
... application, each dipole has a bending angle of 2.8, resulting a 3.3 cm sagitta. This sagitta is about 1 cm larger than the PEP-II dipole sagitta of 2.2 cm, but it is still within the dipole good field region of 5 cm. Optics was designed to keep the reused PEP-II quadrupole strengths within their s ...
... application, each dipole has a bending angle of 2.8, resulting a 3.3 cm sagitta. This sagitta is about 1 cm larger than the PEP-II dipole sagitta of 2.2 cm, but it is still within the dipole good field region of 5 cm. Optics was designed to keep the reused PEP-II quadrupole strengths within their s ...
Lesson Overview - Diman Regional
... What are the components of the endocrine system? The endocrine system is made up of glands that release hormones into the blood. Hormones deliver messages throughout the body. ...
... What are the components of the endocrine system? The endocrine system is made up of glands that release hormones into the blood. Hormones deliver messages throughout the body. ...
Lectin Labeling of Sprouting Neurons I. Regional Distribution of
... microscope if its center fell into the most superficial 5 nm on either side of the section because at least half of it would be cut away. Accordingly, the estimated section thickness was reduced by 2 x 5 not in order to obtain the value for SQ (50 nm). Thus, visible particles per unit area of membra ...
... microscope if its center fell into the most superficial 5 nm on either side of the section because at least half of it would be cut away. Accordingly, the estimated section thickness was reduced by 2 x 5 not in order to obtain the value for SQ (50 nm). Thus, visible particles per unit area of membra ...
File
... Cells are bound together in three ways: 1. Glycoproteins in the glycocalyx act as an adhesive or cellular glue 2. Wavy contours of the membranes of adjacent cells fit together in a tongue-and-groove fashion 3. Special membrane junctions are formed, which vary structurally depending on their roles ...
... Cells are bound together in three ways: 1. Glycoproteins in the glycocalyx act as an adhesive or cellular glue 2. Wavy contours of the membranes of adjacent cells fit together in a tongue-and-groove fashion 3. Special membrane junctions are formed, which vary structurally depending on their roles ...
The Respiratory System
... which involves inspiration and expiration. • The volume of air that is taken into the lungs can increase if the need for oxygen increases, such as during exercise. • External respiration takes place in the lungs, between the air in the alveoli and the blood in the capillaries. ...
... which involves inspiration and expiration. • The volume of air that is taken into the lungs can increase if the need for oxygen increases, such as during exercise. • External respiration takes place in the lungs, between the air in the alveoli and the blood in the capillaries. ...
Retinal Ganglion Cells in Goldfish
... dritic development depends not only on the age and subtype of the cell, but on extrinsic factors as well. Consistent with this interpretation is the demonstration that the coverage of the retina by this cell remains relatively constant with growth. How dendritic trees develop a particular size and s ...
... dritic development depends not only on the age and subtype of the cell, but on extrinsic factors as well. Consistent with this interpretation is the demonstration that the coverage of the retina by this cell remains relatively constant with growth. How dendritic trees develop a particular size and s ...
The onset of pigment epithelial proliferation after retinal
... parallel to the original monolayer. Their nuclear membranes are more scalloped than those of normal RPE cell nuclei, and the usual apical-basal surface polarity is not evident. The cell surfaces are lined with many short, undifferentiated processes that sometimes interdigitate with similar processes ...
... parallel to the original monolayer. Their nuclear membranes are more scalloped than those of normal RPE cell nuclei, and the usual apical-basal surface polarity is not evident. The cell surfaces are lined with many short, undifferentiated processes that sometimes interdigitate with similar processes ...
Gene trap insertion into a novel gene expressed during mouse limb
... (PCR) method that allows cloning of the exon just upstream of the reporter gene (Frohman et al., 1988). In this paper, we report a gene-trap event that shows expression in the limb. The limb has been the subject of studies for decades in the chick, because it is readily accessible to experimental ma ...
... (PCR) method that allows cloning of the exon just upstream of the reporter gene (Frohman et al., 1988). In this paper, we report a gene-trap event that shows expression in the limb. The limb has been the subject of studies for decades in the chick, because it is readily accessible to experimental ma ...
Supplemental Figure Legends
... fluorescence that was associated with a more diffuse cytosolic staining, indicative of pore opening. In contrast, calcein fluorescence was retained within the mitochondria of Ppif-/- MEFs, indicative of pore inhibition (data were collected from two independent experiments each performed in duplicate ...
... fluorescence that was associated with a more diffuse cytosolic staining, indicative of pore opening. In contrast, calcein fluorescence was retained within the mitochondria of Ppif-/- MEFs, indicative of pore inhibition (data were collected from two independent experiments each performed in duplicate ...
Synthesis and sorting of proteoglycans
... interactions, normally of ionic nature, with growth factors, for example. Recent studies have identified ~30 PG protein cores. These cores are not just scaffolds for GAGs: they contain domains that have particular biological activities (Iozzo, 1998). Many PGs are thus multifunctional molecules that ...
... interactions, normally of ionic nature, with growth factors, for example. Recent studies have identified ~30 PG protein cores. These cores are not just scaffolds for GAGs: they contain domains that have particular biological activities (Iozzo, 1998). Many PGs are thus multifunctional molecules that ...
Endovascular Stent Grafting in Posttraumatic Tibial Artery
... 7 months. All the patients had significant peripheral vascular disease of the parent arteries and most of them were not adequately anticoagulated. In one of our cases, the stent remained patent at 2 years of follow-up, suggesting a durable treatment outcome. It can be assumed that the results will be ...
... 7 months. All the patients had significant peripheral vascular disease of the parent arteries and most of them were not adequately anticoagulated. In one of our cases, the stent remained patent at 2 years of follow-up, suggesting a durable treatment outcome. It can be assumed that the results will be ...
Molecular Regulation of Vascular Cambium Identity and Activity
... carry a great potential to be utilised as a feedstock for biofuel production as an alternative to fossil fuels or to produce other important chemicals in biorefinery applications (Plomion et al., 2001; Gomez et al., 2008; Karp & Shield, 2008; Nieminen et al., 2012). Wood conducts water from the root ...
... carry a great potential to be utilised as a feedstock for biofuel production as an alternative to fossil fuels or to produce other important chemicals in biorefinery applications (Plomion et al., 2001; Gomez et al., 2008; Karp & Shield, 2008; Nieminen et al., 2012). Wood conducts water from the root ...
Challenges to our current view on chloroplasts
... The current textbook view on the structure of chloroplasts is rather simplistic: mostly the organelles are drawn as lens-shaped entities surrounded by a double membrane of lipid bilayers. Obviously, it is an enigma how such entities could retain or even change their shape. Moreover, the situation be ...
... The current textbook view on the structure of chloroplasts is rather simplistic: mostly the organelles are drawn as lens-shaped entities surrounded by a double membrane of lipid bilayers. Obviously, it is an enigma how such entities could retain or even change their shape. Moreover, the situation be ...
Principles of Virology
... What is a virion and what is a virus? Given that viruses are part of the biosphere in which other organisms exist, what/how may viruses exert pressure on evolution? How can viruses be detected and quantified? Why is size not a good feature to classify a virus; what might be a better feature? What ki ...
... What is a virion and what is a virus? Given that viruses are part of the biosphere in which other organisms exist, what/how may viruses exert pressure on evolution? How can viruses be detected and quantified? Why is size not a good feature to classify a virus; what might be a better feature? What ki ...
The Peter Doherty Institute for Infection and Immunity Department of
... Development of autoimmune diseases has been linked to disturbances in the microbes that normally colonise our body surfaces (microbiota). However, precisely how these microorganisms and the resulting stimulation of the immune system impact on T cells still remains elusive. Building on exciting new f ...
... Development of autoimmune diseases has been linked to disturbances in the microbes that normally colonise our body surfaces (microbiota). However, precisely how these microorganisms and the resulting stimulation of the immune system impact on T cells still remains elusive. Building on exciting new f ...
Interleukin 1 Receptor Antagonist (IL-1Ra) Is an Acute-Phase
... Similar to APP, serum levels of IL-1Ra can rise dramatically during different inflammatory and noninflammatory conditions such as sepsis (12), chronic rheumatic diseases (13–15), and noninflammatory tissue injury (16). Although a variety of cells have been shown to produce IL-1Ra, little is known ab ...
... Similar to APP, serum levels of IL-1Ra can rise dramatically during different inflammatory and noninflammatory conditions such as sepsis (12), chronic rheumatic diseases (13–15), and noninflammatory tissue injury (16). Although a variety of cells have been shown to produce IL-1Ra, little is known ab ...
A High-Resolution Transcript Profile across the
... and replicates were therefore included both at the level of technical replicates (at least three per section) and, most importantly, biological replicates in form of the two series CSA and CSB taken from individual trees. The experimental system used presents a challenge in assessing whether a gene ...
... and replicates were therefore included both at the level of technical replicates (at least three per section) and, most importantly, biological replicates in form of the two series CSA and CSB taken from individual trees. The experimental system used presents a challenge in assessing whether a gene ...
Integrins and cell differentiation
... contrary, absence of the αPS2 subunit leads to reduced expression of β1 tubulin, but this reduction is less strong than that observed in βPS mutant embryos (compare C with Fig. 1C). When both αPS1 and αPS2 subunits (D) are removed, we observe a stronger reduction in β1 tubulin levels, similar to the ...
... contrary, absence of the αPS2 subunit leads to reduced expression of β1 tubulin, but this reduction is less strong than that observed in βPS mutant embryos (compare C with Fig. 1C). When both αPS1 and αPS2 subunits (D) are removed, we observe a stronger reduction in β1 tubulin levels, similar to the ...
silicone rubber in a parallel plate flow chamber in the absence and
... Pseudomonas aeruginosa and Escherichia coli to orthopaedic implant polymers for organisms suspended in phosphate-buffered saline (PBS), tryptic soy broth and hyaluronic acid. They found that adhesion in whole broth was decreased compared to adhesion in buffer, while the presence of hyaluronic acid i ...
... Pseudomonas aeruginosa and Escherichia coli to orthopaedic implant polymers for organisms suspended in phosphate-buffered saline (PBS), tryptic soy broth and hyaluronic acid. They found that adhesion in whole broth was decreased compared to adhesion in buffer, while the presence of hyaluronic acid i ...
Growth and killing of a Salmonella enterica serovar
... their survival and replication within the host cells. Some survive and replicate within a membrane-bound vacuole modified by the bacteria to support microbial growth (e.g. Salmonella enterica serovar Typhimurium), whereas others escape from the vacuole into the host cell cytosol, where they prolifer ...
... their survival and replication within the host cells. Some survive and replicate within a membrane-bound vacuole modified by the bacteria to support microbial growth (e.g. Salmonella enterica serovar Typhimurium), whereas others escape from the vacuole into the host cell cytosol, where they prolifer ...
Anion homeostasis is important for non
... generally assumed that non-enveloped viruses are released through passive means such as cell lysis, recent evidence for a range of non-enveloped viruses suggests this may not always be the case. Poliovirus has been shown to induce the formation of autophagosome-like vesicles that are involved in vir ...
... generally assumed that non-enveloped viruses are released through passive means such as cell lysis, recent evidence for a range of non-enveloped viruses suggests this may not always be the case. Poliovirus has been shown to induce the formation of autophagosome-like vesicles that are involved in vir ...