BMC Genomics - LCBB
... Background: Genome evolution is shaped not only by nucleotide substitutions, but also by structural changes including gene and genome duplications, insertions, deletions and gene order rearrangements. The most popular methods for reconstructing phylogeny from genome rearrangements include GRAPPA and ...
... Background: Genome evolution is shaped not only by nucleotide substitutions, but also by structural changes including gene and genome duplications, insertions, deletions and gene order rearrangements. The most popular methods for reconstructing phylogeny from genome rearrangements include GRAPPA and ...
IACP DNA Brochure (For PDF)
... In fact! many law enforcement officials consider forensic DNA analysis the most significant advance in forensic science since fingerprints# As a result! states are rapidly expanding the scope and size of their CODIS databases# Over the past five years about one"half of the states have expanded the s ...
... In fact! many law enforcement officials consider forensic DNA analysis the most significant advance in forensic science since fingerprints# As a result! states are rapidly expanding the scope and size of their CODIS databases# Over the past five years about one"half of the states have expanded the s ...
Evolutionary history of the genus Capra
... Mitochondrial (mt) DNA has characteristics making it ideal for phylogenetic studies. It is haploid, with no recombination and uniquely maternal inheritance. Likewise, the Y-chromosome is a useful molecule for phylogenetic studies. This sex chromosome is paternally inherited and, with the exception o ...
... Mitochondrial (mt) DNA has characteristics making it ideal for phylogenetic studies. It is haploid, with no recombination and uniquely maternal inheritance. Likewise, the Y-chromosome is a useful molecule for phylogenetic studies. This sex chromosome is paternally inherited and, with the exception o ...
REVIEWS - Ken Wolfe`s
... duplicated chromosomes into smaller blocks by reciprocal translocation between chromosomes, as envisaged by a polyploidy model41,54, but to reconcile this observation with a segmental duplication model it is necessary postulate that when sections of chromosome are copied to remote sites in the genom ...
... duplicated chromosomes into smaller blocks by reciprocal translocation between chromosomes, as envisaged by a polyploidy model41,54, but to reconcile this observation with a segmental duplication model it is necessary postulate that when sections of chromosome are copied to remote sites in the genom ...
Lecture 13. Mutation
... nucleotide is almost always removed in the course of proof-reading, and this does not happen only with probability 10−4-5. As the result, the per nucleotide mutation rate is only ~10−9. Because no process can be perfectly selective, the proof-reading exonuclease also removes a fraction (up to ~50%) ...
... nucleotide is almost always removed in the course of proof-reading, and this does not happen only with probability 10−4-5. As the result, the per nucleotide mutation rate is only ~10−9. Because no process can be perfectly selective, the proof-reading exonuclease also removes a fraction (up to ~50%) ...
Scanning Life`s Matrix: Genes, Proteins, and Small Molecules (2002
... learned about. These days, they probably teach you about this in third grade now or something. But Mendel is my hero, and I can't not mention Mendel, because his incredible clarity really organized the ideas of genetics for us, the idea of taking 2 pure-breeding strains-- in this case, green pea and ...
... learned about. These days, they probably teach you about this in third grade now or something. But Mendel is my hero, and I can't not mention Mendel, because his incredible clarity really organized the ideas of genetics for us, the idea of taking 2 pure-breeding strains-- in this case, green pea and ...
Symbiotic DNA in eukaryotic genomes
... dispersing themselves among the chromosomes, and increasing their likelihood of infecting new sexual lineages. In a cross between individuals with and without a mobile element, the element is inherited by 50-100% of the offspring, depending on the efficiency of its intragenomic replication. A mobile ...
... dispersing themselves among the chromosomes, and increasing their likelihood of infecting new sexual lineages. In a cross between individuals with and without a mobile element, the element is inherited by 50-100% of the offspring, depending on the efficiency of its intragenomic replication. A mobile ...
Genome Biology and Evolution
... Monophlebidae. Further analyses should be done to determine whether other Flavobacteria that have been previously obtained from insects of the family Coccidae and Lecanodiaspididae whose 16S rRNA sequences are phylogenetically related to Walczuchella monophlebidarum (Rosenblueth et al. 2012) could b ...
... Monophlebidae. Further analyses should be done to determine whether other Flavobacteria that have been previously obtained from insects of the family Coccidae and Lecanodiaspididae whose 16S rRNA sequences are phylogenetically related to Walczuchella monophlebidarum (Rosenblueth et al. 2012) could b ...
Lacroix_Insyght navigating amongst abundant - Migale
... High-throughput sequencing technologies have become commonplace and biologists need tools that assist them in annotating gene functions quickly and accurately at a genome-wide scale. Together with sequence similarity, gene neighbourhood conservation and phylogenetic profiles provide important clues ...
... High-throughput sequencing technologies have become commonplace and biologists need tools that assist them in annotating gene functions quickly and accurately at a genome-wide scale. Together with sequence similarity, gene neighbourhood conservation and phylogenetic profiles provide important clues ...
Polymorphisms in Multiple Genes Contribute to the
... direct-repeat recombination involving short homologous sequences (Gaillard and Bernardi 1979; Gaillard et al. 1980). However, neither the defects in mtDNA processing that lead to direct-repeat recombination nor the conditions that may determine its occurrence are known. Given the large number of gen ...
... direct-repeat recombination involving short homologous sequences (Gaillard and Bernardi 1979; Gaillard et al. 1980). However, neither the defects in mtDNA processing that lead to direct-repeat recombination nor the conditions that may determine its occurrence are known. Given the large number of gen ...
Van, C., Williams, J.S., Kunkel, T.A., and
... To our knowledge, this is the first demonstration that a defect in SWR-C-dependent chromatin remodeling reduces genome stability. This effect is specific for single base changes generated by L612M Pol δ. Hypothetically, these mutations could reflect a SWR-Cdependent defect in any of several cellular ...
... To our knowledge, this is the first demonstration that a defect in SWR-C-dependent chromatin remodeling reduces genome stability. This effect is specific for single base changes generated by L612M Pol δ. Hypothetically, these mutations could reflect a SWR-Cdependent defect in any of several cellular ...
Document
... outcome of a sequencing project are masses of raw data The challenge is to turn these raw data into biological knowledge A valuable tool for this challenge is an automated diagnostic pipe through which newly determined sequences can be streamlined ...
... outcome of a sequencing project are masses of raw data The challenge is to turn these raw data into biological knowledge A valuable tool for this challenge is an automated diagnostic pipe through which newly determined sequences can be streamlined ...
Genome Research 13, 8 - Tel
... Department of Computer Science, Tel-Hai Academic College, Upper Galilee 12210, Israel A new measure for gene prediction in eukaryotes is presented. The measure is based on the Discrete Fourier Transform (DFT) phase at a frequency of 1/3, computed for the four binary sequences for A, T, C, and G. Ana ...
... Department of Computer Science, Tel-Hai Academic College, Upper Galilee 12210, Israel A new measure for gene prediction in eukaryotes is presented. The measure is based on the Discrete Fourier Transform (DFT) phase at a frequency of 1/3, computed for the four binary sequences for A, T, C, and G. Ana ...
Recessive mutations
... Mutation at the Cellular Level • Somatic Mutation – arises in body cells that will not give rise to gametes (not passed to offspring) – can lead to mutant cell population – mutation of proto-oncogenes leads to cancer ...
... Mutation at the Cellular Level • Somatic Mutation – arises in body cells that will not give rise to gametes (not passed to offspring) – can lead to mutant cell population – mutation of proto-oncogenes leads to cancer ...
Genome reduction as the dominant mode of evolution
... gene presence-absence in the analyzed species. The patterns are superimposed on the evolutionary tree of these species and the gene compositions of the ancestral forms as well as the gene losses and gain along the tree branches are reconstructed using either maximum parsimony (MP) or maximum likelih ...
... gene presence-absence in the analyzed species. The patterns are superimposed on the evolutionary tree of these species and the gene compositions of the ancestral forms as well as the gene losses and gain along the tree branches are reconstructed using either maximum parsimony (MP) or maximum likelih ...
Justification of Size Estimates for Tomato Genome Sequencing
... Additional Information. When the sequencing project is advanced to the stage where BAC contigs can be assayed for both total non-redundant sequence length and physical distance based on in situ hybridization, we will be able to develop an additional estimate of euchromatin physical size through vali ...
... Additional Information. When the sequencing project is advanced to the stage where BAC contigs can be assayed for both total non-redundant sequence length and physical distance based on in situ hybridization, we will be able to develop an additional estimate of euchromatin physical size through vali ...
American College of Medical Genetics and Genomics
... that is IBD is 6.25%, the SD is 2.43%.5 The expected percentages are based on a single common ancestor; however, multiple loops of consanguinity or multiple generations of breeding within a relatively closed community could complicate the estimation of the degree of relationship. These variations fr ...
... that is IBD is 6.25%, the SD is 2.43%.5 The expected percentages are based on a single common ancestor; however, multiple loops of consanguinity or multiple generations of breeding within a relatively closed community could complicate the estimation of the degree of relationship. These variations fr ...
Jianfeng Xu, MD, DrPH: GWA - UCLA School of Public Health
... The above approaches may limit the number of false positives Confirmation is needed to dissect true from false positives ...
... The above approaches may limit the number of false positives Confirmation is needed to dissect true from false positives ...
Identification of large-scale human-specific copy number
... single DNA samples, possibly due to an enhanced detection rate of intra-species CNDs. In the final evaluation, however, only those CNDs that were detected in the experiments using pooled DNAs were taken into account. A total of 347 BACs displayed significant variation in the intensity ratio between th ...
... single DNA samples, possibly due to an enhanced detection rate of intra-species CNDs. In the final evaluation, however, only those CNDs that were detected in the experiments using pooled DNAs were taken into account. A total of 347 BACs displayed significant variation in the intensity ratio between th ...
Transposable element contributions to plant gene and
... Transposable elements were first discovered in plants because they can have tremendous effects on genome structure and gene function. Although only a few or no elements may be active within a genome at any time in any individual, the genomic alterations they cause can have major outcomes for a speci ...
... Transposable elements were first discovered in plants because they can have tremendous effects on genome structure and gene function. Although only a few or no elements may be active within a genome at any time in any individual, the genomic alterations they cause can have major outcomes for a speci ...
Case Study: Visualization of annotated DNA sequences
... semantic zooming and annotation comparison, but zooming and panning is not real-time (VIII) and the browser does not support DNA sequence comparisons (X). Therefore, we have developed a DNA visualization tool that fulfills all defined requirements. DNAVis is written in C++ and runs on both Windows a ...
... semantic zooming and annotation comparison, but zooming and panning is not real-time (VIII) and the browser does not support DNA sequence comparisons (X). Therefore, we have developed a DNA visualization tool that fulfills all defined requirements. DNAVis is written in C++ and runs on both Windows a ...
Creating a Venn diagram and list for unique genes from RAST
... Open Firefox (this is the browser that works best with RAST) Go to rast.nmpdr.org Login to RAST (username: newmanlab password: 16srrna1) In the Jobs Overview window, find the organism you wish to focus on by searching the Name column and click View Details under Annotation Progress In the Job ...
... Open Firefox (this is the browser that works best with RAST) Go to rast.nmpdr.org Login to RAST (username: newmanlab password: 16srrna1) In the Jobs Overview window, find the organism you wish to focus on by searching the Name column and click View Details under Annotation Progress In the Job ...
Genes for Two Mitochondrial Ribosomal Proteins in
... in other angiosperms and the nuclear gene for chloroplast RPS13 from Arabidopsis (Kumar et al., 1995), cotton, and soybean. Considering that the last common ancestor of cotton and legumes also was an ancestor of Arabidopsis, we predicted that the Arabidopsis nucleus also might contain a homologous r ...
... in other angiosperms and the nuclear gene for chloroplast RPS13 from Arabidopsis (Kumar et al., 1995), cotton, and soybean. Considering that the last common ancestor of cotton and legumes also was an ancestor of Arabidopsis, we predicted that the Arabidopsis nucleus also might contain a homologous r ...
Draft-press-release-for-SA-press
... genes (HOX genes) of the coelacanth. At that time there was no completely sequenced genome sequence. About a year ago, Christoffels was invited to participate in the genomic analysis of the Coelacanth genome together with his team from UWC’s South African Bioinformatics Institute (SANBI). The team i ...
... genes (HOX genes) of the coelacanth. At that time there was no completely sequenced genome sequence. About a year ago, Christoffels was invited to participate in the genomic analysis of the Coelacanth genome together with his team from UWC’s South African Bioinformatics Institute (SANBI). The team i ...
08.seg_dup_els - NYU Computer Science
... In a modern genome, one detects duplications of both gene and non-genic regions, as they occur in different scales: namely, gene duplications, large segmental duplications, chromosomal duplications resulting in poly-ploidy and whole-genome duplications. For instance, from the sequence of a related s ...
... In a modern genome, one detects duplications of both gene and non-genic regions, as they occur in different scales: namely, gene duplications, large segmental duplications, chromosomal duplications resulting in poly-ploidy and whole-genome duplications. For instance, from the sequence of a related s ...