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Exercise 11 - Understanding the Output for a blastn Search
Exercise 11 - Understanding the Output for a blastn Search

... When we design a BLAST search, there are three basic decisions we must make: the BLAST program we wish to use, the query sequence we want to annotate, and the database we want to search. In addition, there are several optional parameters (such as the ‘expect’ threshold and other scoring parameters) ...
Chapter 2: Fundamentals of the Analysis of Algorithm
Chapter 2: Fundamentals of the Analysis of Algorithm

... It cannot be investigated the way the previous examples are. ...
Algorithms examples Correctness and testing
Algorithms examples Correctness and testing

... • This condition is called a loop invariant. • The proof is made by induction on the number i of executions of the body of the while loop. • If i=0 then the result is trivial because m = m0 and n = n0. • For the induction step we assume that at the end of the ith execution of the while loop we have ...
BIO 4333/6V29: DNA Replication, Recombination, and Repair
BIO 4333/6V29: DNA Replication, Recombination, and Repair

BLAST - UPCH
BLAST - UPCH

Speeding up the Consensus Clustering methodology for microarray
Speeding up the Consensus Clustering methodology for microarray

... • NMF: Non negative Matrix Factorization, can also use another algorithm’s solution as a starting point(NMF, NMF-R, NMF-C, NMF-S) ...
Lecture 4 — August 14 4.1 Recap 4.2 Actions model
Lecture 4 — August 14 4.1 Recap 4.2 Actions model

Optimization of Aperiodically Spaced Antenna Arrays for Wideband
Optimization of Aperiodically Spaced Antenna Arrays for Wideband

... simulates the “swarming” nature of bees when searching for food  Semi-heuristic method  Utilizes both local search and ...
L10: k-Means Clustering
L10: k-Means Clustering

... • Random set of k points. By coupon collectors, we know that we need about k log k to get one in each cluster. • Randomly partition X = {X1 , X2 , . . . , Xk } and take ci = average(Xi ). This biases towards “center” of X (by Chernoff-Hoeffding). • Gonzalez algorithm (for k-center). This biases too ...
Document
Document

Diapositiva 1 - Universidad Autonoma de Madrid
Diapositiva 1 - Universidad Autonoma de Madrid

... Assumptions: variation in substitution rate ...
Lec-GenomeAllignment2010
Lec-GenomeAllignment2010

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Lecture

Full text
Full text

... function (1 - x - x2 - ••• - xk)~l was found by V. Schlegel in 1894. See [1, Chap. XVII] for this and other classical references. An alternate solution to the problem can be obtained as follows. Consider a sequence of experiments: Toss a p-coin Xl times, until a sequence of k - 1 heads occurs. Then ...
Slide 1
Slide 1

PPTX - UT Computer Science
PPTX - UT Computer Science

... Metagenomic Taxon Identification Objective: classify short reads in a metagenomic sample ...
Bioinformatics to Study PTC Bitter Taste Receptor 1. Go to Kathryn
Bioinformatics to Study PTC Bitter Taste Receptor 1. Go to Kathryn

String-Matching Problem
String-Matching Problem

... Rabin-Karp Algorithm Correctness : T is a string of characters over an alphabet of size d, P is string of characters over an alphabet of size d and |P| <= |T|, d is the size of the alphabet and q is a prime number ...
Slides 4 - UF CISE - University of Florida
Slides 4 - UF CISE - University of Florida

... • Different levels of the BLOSUM matrix can be created by differentially weighting the degree of similarity between sequences. For example, a BLOSUM62 matrix is calculated from protein blocks such that if two sequences are more than 62% identical, then the contribution of these sequences is weighted ...
BLAST Tips - Boston University
BLAST Tips - Boston University

UNIT-I - WordPress.com
UNIT-I - WordPress.com

... on the worst possible set of inputs. Example: Linear Search ...
Greedy Algorithms
Greedy Algorithms

... – If there is no decreasing strip, there may be no reversal r that reduces the number of breakpoints (i.e. b(p• r) ≥ b(p) for any reversal r). – By reversing an increasing strip ( # of breakpoints stay unchanged ), we will create a decreasing strip at the next step. Then the number of breakpoints w ...
Bioinformatics with basic local alignment search tool (BLAST) and
Bioinformatics with basic local alignment search tool (BLAST) and

... 1988). There are three main types of sequence alignments: pairwise sequence alignment, multiple sequence alignment and structural sequence alignment (Pearson and Lipman, 1988; Luscombe et al., 2001). Pairwise sequence alignment can only be used between two sequences at a time. Multiple sequence alig ...
Greedy Algorithms - University of Illinois at Urbana
Greedy Algorithms - University of Illinois at Urbana

... • ImprovedBreakPointReversalSort is an approximation algorithm with a performance guarantee of at most 4 – It eliminates at least one breakpoint in every two steps; at most 2b(p) steps – Approximation ratio: 2b(p) / d(p) – Optimal algorithm eliminates at most 2 breakpoints in every step: d(p)  b(p) ...
Datasheet - Mouser Electronics
Datasheet - Mouser Electronics

... Shelf Life @ 25°C (months) ...
< 1 ... 9 10 11 12 13 14 15 16 17 ... 21 >

Smith–Waterman algorithm

The Smith–Waterman algorithm performs local sequence alignment; that is, for determining similar regions between two strings or nucleotide or protein sequences. Instead of looking at the total sequence, the Smith–Waterman algorithm compares segments of all possible lengths and optimizes the similarity measure.The algorithm was first proposed by Temple F. Smith and Michael S. Waterman in 1981. Like the Needleman–Wunsch algorithm, of which it is a variation, Smith–Waterman is a dynamic programming algorithm. As such, it has the desirable property that it is guaranteed to find the optimal local alignment with respect to the scoring system being used (which includes the substitution matrix and the gap-scoring scheme). The main difference to the Needleman–Wunsch algorithm is that negative scoring matrix cells are set to zero, which renders the (thus positively scoring) local alignments visible. Backtracking starts at the highest scoring matrix cell and proceeds until a cell with score zero is encountered, yielding the highest scoring local alignment. One does not actually implement the algorithm as described because improved alternatives are now available that have better scaling (Gotoh, 1982) and are more accurate (Altschul and Erickson, 1986).
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