The J-Curve Phenomenon in Stroke Recurrence
... reported that diastolic hypertension (greater than 100 mm Hg) at the time of the initial examination was a significant risk factor for stroke recurrence. The relative risk ratio, however, was quite modest (95% confidence interval, 1.003 to 1.021). In a community study in Rochester, Minn, neither lev ...
... reported that diastolic hypertension (greater than 100 mm Hg) at the time of the initial examination was a significant risk factor for stroke recurrence. The relative risk ratio, however, was quite modest (95% confidence interval, 1.003 to 1.021). In a community study in Rochester, Minn, neither lev ...
Hemoglobin Variant Trait - Minnesota Department of Health
... • Hemoglobin is a protein in red blood cells. The job of hemoglobin is to carry oxygen through the body. • Each person inherits two hemoglobin genes – one from each parent. A normal gene will make normal hemoglobin (A). A specific change in the hemoglobin gene will make hemoglobin variant (V). »» ...
... • Hemoglobin is a protein in red blood cells. The job of hemoglobin is to carry oxygen through the body. • Each person inherits two hemoglobin genes – one from each parent. A normal gene will make normal hemoglobin (A). A specific change in the hemoglobin gene will make hemoglobin variant (V). »» ...
Carotid Chemoreceptors and Blood Pressure
... branches of the carotid sinus nerves may be damaged and cause baroreflex failure.16–18 Baroreflex failure (sympathoexcitation, hypertension, and tachycardia) is often an early postsurgical response that resolves within months; however, both normalization of blood pressure19 and sustained hypertensio ...
... branches of the carotid sinus nerves may be damaged and cause baroreflex failure.16–18 Baroreflex failure (sympathoexcitation, hypertension, and tachycardia) is often an early postsurgical response that resolves within months; however, both normalization of blood pressure19 and sustained hypertensio ...
Effect of Bilateral Carotid Body Resection on Cardiac Baroreflex
... branches of the carotid sinus nerves may be damaged and cause baroreflex failure.16–18 Baroreflex failure (sympathoexcitation, hypertension, and tachycardia) is often an early postsurgical response that resolves within months; however, both normalization of blood pressure19 and sustained hypertensio ...
... branches of the carotid sinus nerves may be damaged and cause baroreflex failure.16–18 Baroreflex failure (sympathoexcitation, hypertension, and tachycardia) is often an early postsurgical response that resolves within months; however, both normalization of blood pressure19 and sustained hypertensio ...
Methodologies for Detection of Hemoglobin
... that has been chemically treated to induce cross-linking or polymerization (or both). This exogenous hemoglobin is not contained within red blood cells but circulates in the plasma. The chemical modification is essential to prevent the toxic effects associated with high levels of extracellular hemog ...
... that has been chemically treated to induce cross-linking or polymerization (or both). This exogenous hemoglobin is not contained within red blood cells but circulates in the plasma. The chemical modification is essential to prevent the toxic effects associated with high levels of extracellular hemog ...
Kidney Donation by Live Donors
... hospitalisation and follow-up care after discharge. You and the recipient each have your own renal physician before, during and after the transplant. Transplant Co-ordinator will be the first point of contact before the operation, during hospitalisation and after discharge. The transplant co-ordinat ...
... hospitalisation and follow-up care after discharge. You and the recipient each have your own renal physician before, during and after the transplant. Transplant Co-ordinator will be the first point of contact before the operation, during hospitalisation and after discharge. The transplant co-ordinat ...
18. The role of blood flow in glaucoma
... blood flow through the range of pressures created by pulsatility.6 This is important since a relatively constant amount of blood needs to perfuse through a mass of tissue in order to prevent ischemic tissue damage. Without the ability to regulate blood flow, pulsatile blood flow would result in vari ...
... blood flow through the range of pressures created by pulsatility.6 This is important since a relatively constant amount of blood needs to perfuse through a mass of tissue in order to prevent ischemic tissue damage. Without the ability to regulate blood flow, pulsatile blood flow would result in vari ...
The role of endoscopy in the management of acute non
... Vascular malformations typically cause chronic occult blood loss and occasionally acute GI hemorrhage. These lesions can occur sporadically or in association with other disorders, such as cirrhosis, renal failure, radiation injury, various collagen vascular diseases, and hereditary hemorrhagic telan ...
... Vascular malformations typically cause chronic occult blood loss and occasionally acute GI hemorrhage. These lesions can occur sporadically or in association with other disorders, such as cirrhosis, renal failure, radiation injury, various collagen vascular diseases, and hereditary hemorrhagic telan ...
A microscopic view on the renal endothelial glycocalyx - AJP
... PAR signaling induces a quiescent phenotype in the endothelium (39, 82). Activation of this pathway could prevent the development of diabetic nephropathy, underscoring the importance of APC formation in prevention of kidney disease (39). Finally, thrombomodulin-thrombin binding activates thrombin-ac ...
... PAR signaling induces a quiescent phenotype in the endothelium (39, 82). Activation of this pathway could prevent the development of diabetic nephropathy, underscoring the importance of APC formation in prevention of kidney disease (39). Finally, thrombomodulin-thrombin binding activates thrombin-ac ...
Antihypertensive Medications Prescribed at Discharge After
... history of hypertension or diabetes were more likely to receive a prescription for an antihypertensive at the time of hospital discharge. At first glance, the fact that a majority of hospitalized ischemic stroke and TIA patients are discharged on ⱖ1 antihypertensive drug may seem encouraging. Howeve ...
... history of hypertension or diabetes were more likely to receive a prescription for an antihypertensive at the time of hospital discharge. At first glance, the fact that a majority of hospitalized ischemic stroke and TIA patients are discharged on ⱖ1 antihypertensive drug may seem encouraging. Howeve ...
Conference Abstracts - Canadian Society for Transfusion Medicine
... The impact of gamma irradiation on quality parameters and function during a 9-day storage of platelets prepared with the new REVEOS system ............................................................................. 148 The impact of pathogen inactivation treatment on selected platelet mRNA transcr ...
... The impact of gamma irradiation on quality parameters and function during a 9-day storage of platelets prepared with the new REVEOS system ............................................................................. 148 The impact of pathogen inactivation treatment on selected platelet mRNA transcr ...
The Definition of Minimal Extrathyroid Extension in Thyroid
... thyroid carcinomas. However, many uncertainties and controversies still remain. Among them, the definition of minimal extrathyroid extension (ETE), which is known as one of the prognostic factors of thyroid carcinoma, must be clarified.1 Embryologically, anatomically, or histologically, there is no ...
... thyroid carcinomas. However, many uncertainties and controversies still remain. Among them, the definition of minimal extrathyroid extension (ETE), which is known as one of the prognostic factors of thyroid carcinoma, must be clarified.1 Embryologically, anatomically, or histologically, there is no ...
Anesthesia for neurosurgery - Neuroanesthesia
... diuretic, mannitol draws water from the brain and other tissues into the intravascular compartment. Mannitol may also lower ICP by decreasing blood viscosity and expanding plasma volume which increase CBF. When autoregulation is intact this prompts vasoconstriction to restore CBF towards normal [37] ...
... diuretic, mannitol draws water from the brain and other tissues into the intravascular compartment. Mannitol may also lower ICP by decreasing blood viscosity and expanding plasma volume which increase CBF. When autoregulation is intact this prompts vasoconstriction to restore CBF towards normal [37] ...
VEGFA in yolk sac endoderm - Development
... absolutely required for proper blood island formation (Miura and Wilt, 1969). This observation was confirmed by a later study that investigated Gata4–/– embryoid bodies that could not form visceral endoderm. In this study, Bielinska et al. demonstrated that formation and organisation of blood island ...
... absolutely required for proper blood island formation (Miura and Wilt, 1969). This observation was confirmed by a later study that investigated Gata4–/– embryoid bodies that could not form visceral endoderm. In this study, Bielinska et al. demonstrated that formation and organisation of blood island ...
Sepsis and pregnancy: do we know how to treat this situation?
... therapy (EGDT) criteria:(39) central venous pressure (CVP) equal to 8 to 12 mmHg, mean arterial pressure (MAP) ≥65mmHg, urine output ≥0.5mL/kg/h, and central venous oxygen saturation (ScvO2) ≥70% or ...
... therapy (EGDT) criteria:(39) central venous pressure (CVP) equal to 8 to 12 mmHg, mean arterial pressure (MAP) ≥65mmHg, urine output ≥0.5mL/kg/h, and central venous oxygen saturation (ScvO2) ≥70% or ...
A perspective on Serum Lactic acid, Lactic Acidosis in a Critical
... resulted from the overproduction of lactate and that the clearance process was similar in all three groups. Excess lactate production could be one of the likely contributors to hyperlactatemia in critically ill patients. Levraut et al. [7] showed that in patients with hemodynamically stable sepsis, ...
... resulted from the overproduction of lactate and that the clearance process was similar in all three groups. Excess lactate production could be one of the likely contributors to hyperlactatemia in critically ill patients. Levraut et al. [7] showed that in patients with hemodynamically stable sepsis, ...
The Effects of Natural Antioxidants from Tomato
... of lycopene; nitrate and blood pressure, assessed after 6 weeks of placebo treatment, compared to the result of 6 weeks tomato extract supplementation for the whole study population. Mean SBP for the combined two groups on placebo was 139.4 ± 11.6 vs. 130 ± 9.6 mmHg on tomato extract (p < 0.001), wh ...
... of lycopene; nitrate and blood pressure, assessed after 6 weeks of placebo treatment, compared to the result of 6 weeks tomato extract supplementation for the whole study population. Mean SBP for the combined two groups on placebo was 139.4 ± 11.6 vs. 130 ± 9.6 mmHg on tomato extract (p < 0.001), wh ...
Clinical Practice Guideline - Emergency Nurses Association
... baroreceptors (Aung, 2013). However, conditions leading to hypovolemia and autonomic failure may result in a sudden drop in blood pressure known as orthostatic hypotension (OH) and result in impaired perfusion to the upper body. The American Autonomic Society and the American Academy of Neurology de ...
... baroreceptors (Aung, 2013). However, conditions leading to hypovolemia and autonomic failure may result in a sudden drop in blood pressure known as orthostatic hypotension (OH) and result in impaired perfusion to the upper body. The American Autonomic Society and the American Academy of Neurology de ...
IOSR Journal of Dental and Medical Sciences (IOSR-JDMS)
... decreased but was still lower than pre-treatment value. The results were in agreement to our study. The side effects observed in their study included ovarian cyst (7.1%), gastric upset (7.1%), vague abdominal pain (4.8%) and headache (4.8%). We observed 6 cases of ovarian cyst (12%) in our study. Ot ...
... decreased but was still lower than pre-treatment value. The results were in agreement to our study. The side effects observed in their study included ovarian cyst (7.1%), gastric upset (7.1%), vague abdominal pain (4.8%) and headache (4.8%). We observed 6 cases of ovarian cyst (12%) in our study. Ot ...
Chromosomal Dichotomy in Blood and Marrow
... was not generally confirmed at other laboratories (1-3, 5-8, 10, 11, 14, 18, 21, 22), where attention was paid not merely to numerical aneuploidy but to structural pseudo-diploidy. The investigations of Ford and his collaborators (6-9), like those of Baikie et al. (2, 3), were based largely on cultu ...
... was not generally confirmed at other laboratories (1-3, 5-8, 10, 11, 14, 18, 21, 22), where attention was paid not merely to numerical aneuploidy but to structural pseudo-diploidy. The investigations of Ford and his collaborators (6-9), like those of Baikie et al. (2, 3), were based largely on cultu ...
Hemoglobin C Trait - Perinatal Services BC
... levels in your blood are low. They look like a sickle. The sickled red blood cells can become stuck in small blood vessels, block the blood supply and cause pain and damage in that part of the body. They also cause a low blood count that makes the person tired and short of breath. This is called ane ...
... levels in your blood are low. They look like a sickle. The sickled red blood cells can become stuck in small blood vessels, block the blood supply and cause pain and damage in that part of the body. They also cause a low blood count that makes the person tired and short of breath. This is called ane ...
Asymmetric Dimethylarginine
... There are multiple dietary and nutrient-dependent steps involved in the control of ADMA synthesis and clearance. L-Arginine stimulates NO synthesis to overcome the inhibitory effects of high ADMA. Low fat meals help to reduce the synthesis of ADMA by PRMT. Vitamin A induces expression of DDAH, causi ...
... There are multiple dietary and nutrient-dependent steps involved in the control of ADMA synthesis and clearance. L-Arginine stimulates NO synthesis to overcome the inhibitory effects of high ADMA. Low fat meals help to reduce the synthesis of ADMA by PRMT. Vitamin A induces expression of DDAH, causi ...
Control of Regional Blood Flow by Endothelium
... L-NMMA (0.3-30 mg/kg) induced a dosedependent increase in mean blood pressure and a decrease in heart rate that were maximal within 2 minutes and had generally stabilized by 5 minutes. The effects were not significantly different between those rats with renal, mesenteric, and hindquarters probes and ...
... L-NMMA (0.3-30 mg/kg) induced a dosedependent increase in mean blood pressure and a decrease in heart rate that were maximal within 2 minutes and had generally stabilized by 5 minutes. The effects were not significantly different between those rats with renal, mesenteric, and hindquarters probes and ...
Volume 26 - No 23: Nutrionally Deficient Streptococcus
... species as Streptococcus adjacens and Streptococcus defectivus. However, sequence analysis of the 16S rRNA gene revealed that these two species were not related to any species; therefore, a new genus Abiotrophia was created (Kawamura et al, 1995). Interestingly, further studies have converted most o ...
... species as Streptococcus adjacens and Streptococcus defectivus. However, sequence analysis of the 16S rRNA gene revealed that these two species were not related to any species; therefore, a new genus Abiotrophia was created (Kawamura et al, 1995). Interestingly, further studies have converted most o ...
Elevated concentrations of sedoheptulose in bloodspots of patients
... detected by newborn screening will be treated early, thereby preventing early renal glomerular deterioration and other symptoms associated with cystinosis [12]. Before the use in newborn screening programs can be considered, several points require further discussion. First, the assessment of sedohep ...
... detected by newborn screening will be treated early, thereby preventing early renal glomerular deterioration and other symptoms associated with cystinosis [12]. Before the use in newborn screening programs can be considered, several points require further discussion. First, the assessment of sedohep ...
Hemolytic-uremic syndrome
Hemolytic-uremic syndrome (or haemolytic-uraemic syndrome), abbreviated HUS, is a disease characterized by hemolytic anemia (anemia caused by destruction of red blood cells), acute kidney failure (uremia), and a low platelet count (thrombocytopenia). It predominantly, but not exclusively, affects children. Most cases are preceded by an episode of infectious, sometimes bloody, diarrhea acquired as a foodborne illness or from a contaminated water supply and caused by E. coli O157:H7, although Shigella, Campylobacter and a variety of viruses have also been implicated. It is now the most common cause of acquired acute renal failure in childhood. It is a medical emergency and carries a 5–10% mortality; of the remainder, the majority recover without major consequences but a small proportion develop chronic kidney disease and become reliant on renal replacement therapy.The primary target appears to be the vascular endothelial cell. This may explain the pathogenesis of HUS, in which a characteristic renal lesion is capillary microangiopathy.HUS was first defined as a syndrome in 1955. The more common form of the disease, Shiga-like toxin-producing E. coli HUS (STEC-HUS), is triggered by the infectious agent E. coli O157:H7. Certain Shiga toxin secreting strains of Shigella dysenteriae can also cause HUS. Approximately 5% of cases are classified as pneumococcal HUS, which results from infection by Streptococcus pneumoniae, the agent that causes traditional lobar pneumonia. There is also a rare, chronic, and severe form known as atypical hemolytic uremic syndrome (aHUS), which is caused by genetic defects resulting in chronic, uncontrolled complement activation. Both STEC-HUS and aHUS cause endothelial damage, leukocyte activation, platelet activation, and widespread inflammation and multiple thromboses in the small blood vessels, a condition known as systemic thrombotic microangiopathy (TMA), which leads to thrombotic events as well as organ damage/failure and death.