
Identification of Short Motifs for Comparing Biological Sequences
... factors would enhance the quality of the comparison results. DNA sequences are not random in their structures, and it is believed that each fragment/subsequence of the DNA sequence carries a message or a signal. The hypothesis used in this research is that closely related or similar genomes would ca ...
... factors would enhance the quality of the comparison results. DNA sequences are not random in their structures, and it is believed that each fragment/subsequence of the DNA sequence carries a message or a signal. The hypothesis used in this research is that closely related or similar genomes would ca ...
Package ‘GenomicFeatures’ October 14, 2014
... A DNAStringSet object containing one upstream sequence per gene (or per transcript if genes is a GenomicRanges object containing transcript ranges). More precisely, if genes is a GenomicRanges object, the returned object is parallel to it, that is, the i-th element in the returned object is the upst ...
... A DNAStringSet object containing one upstream sequence per gene (or per transcript if genes is a GenomicRanges object containing transcript ranges). More precisely, if genes is a GenomicRanges object, the returned object is parallel to it, that is, the i-th element in the returned object is the upst ...
Meiosis Notes
... chromatids, as it would after mitosis. Because each pair of homologous chromosomes was separated, neither daughter cell has the two complete sets of chromosomes that it would have in a diploid cell. The two cells produced by meiosis I have sets of chromosomes and alleles that are different from each ...
... chromatids, as it would after mitosis. Because each pair of homologous chromosomes was separated, neither daughter cell has the two complete sets of chromosomes that it would have in a diploid cell. The two cells produced by meiosis I have sets of chromosomes and alleles that are different from each ...
Temperature-dependent expression of virulence genes in fish
... 2010; Steinmann and Dersch, 2013). In addition, bacteria also have response mechanisms to drastic changes in temperature. The paradigms of this adaptation are the cold and heat shock response systems under which the bacteria induce a fast response to sudden and extreme temperature shift (Guisbert et ...
... 2010; Steinmann and Dersch, 2013). In addition, bacteria also have response mechanisms to drastic changes in temperature. The paradigms of this adaptation are the cold and heat shock response systems under which the bacteria induce a fast response to sudden and extreme temperature shift (Guisbert et ...
Phylogenetic Network and Physicochemical Properties of
... Theories on molecular evolution predict that phylogenetically recent nonsynonymous mutations should contain more non-neutral amino acid replacements than ancient mutations. We analyzed 840 complete coding-region human mitochondrial DNA (mtDNA) sequences for nonsynonymous mutations and evaluated the ...
... Theories on molecular evolution predict that phylogenetically recent nonsynonymous mutations should contain more non-neutral amino acid replacements than ancient mutations. We analyzed 840 complete coding-region human mitochondrial DNA (mtDNA) sequences for nonsynonymous mutations and evaluated the ...
Genetic linkage studies in the pseudoautosomal
... distance between two genes. If the segments were located very close to each other, they would almost never be separated by a crossover, hence Ө would approximate 0. If at the other extreme, the segments were situated very far apart from each other or at different chromosomes, could recombine random ...
... distance between two genes. If the segments were located very close to each other, they would almost never be separated by a crossover, hence Ө would approximate 0. If at the other extreme, the segments were situated very far apart from each other or at different chromosomes, could recombine random ...
Fungal - CBS-KNAW Fungal Biodiversity Centre
... Rhizopus by Blakeslee (1904); and the Wrst molecular characterization of the mating type idiomorphs was achieved for the yeast Saccharomyces cerevisiae (Astell et al., 1981). Neurospora crassa was the Wrst Wlamentous ascomycete for which the mating type genes (MAT1-1-1 and MAT1-2) were cloned and se ...
... Rhizopus by Blakeslee (1904); and the Wrst molecular characterization of the mating type idiomorphs was achieved for the yeast Saccharomyces cerevisiae (Astell et al., 1981). Neurospora crassa was the Wrst Wlamentous ascomycete for which the mating type genes (MAT1-1-1 and MAT1-2) were cloned and se ...
Unit 19 Handout - Chavis Biology
... IB Assessment Statements and Class Objectives 3.3.NOS: Making careful observations- meiosis was discovered by microscope examination of dividing germ-line cells. Discuss difficulties in microscopic examination of dividing cells. Describe the discovery of meiosis. 3.3.U2: The halving of the chrom ...
... IB Assessment Statements and Class Objectives 3.3.NOS: Making careful observations- meiosis was discovered by microscope examination of dividing germ-line cells. Discuss difficulties in microscopic examination of dividing cells. Describe the discovery of meiosis. 3.3.U2: The halving of the chrom ...
Human Genetics - Chapter 5
... • H gene is epistatic to the I gene • H protein places a molecule at the cell surface to which the A or B antigens are attached • hh genotype = no H protein • Without H protein the A or B antigens can not be attached to the surface of the RBC • All hh genotypes have the phenotype of type O, although ...
... • H gene is epistatic to the I gene • H protein places a molecule at the cell surface to which the A or B antigens are attached • hh genotype = no H protein • Without H protein the A or B antigens can not be attached to the surface of the RBC • All hh genotypes have the phenotype of type O, although ...
Phylogeny of elasmobranchs based on LSU and SSU ribosomal
... the last 50 bases of the 5.8S gene from all taxa except Hemiscyllium. These sequences are available in GenBank under Accession No. AY049805-61. Other ...
... the last 50 bases of the 5.8S gene from all taxa except Hemiscyllium. These sequences are available in GenBank under Accession No. AY049805-61. Other ...
Genome-Wide Scan of Obesity in the Old Order Amish*
... Segregation analyses suggest that single genes with relatively large effects as well as polygenes with smaller effects contribute to the development of obesity. Studies in several populations suggest that major genes inherited in a recessive manner may account for 35– 45% of the variation in obesity ...
... Segregation analyses suggest that single genes with relatively large effects as well as polygenes with smaller effects contribute to the development of obesity. Studies in several populations suggest that major genes inherited in a recessive manner may account for 35– 45% of the variation in obesity ...
The Mean Between Meme and Gene Comparison
... between memes and genes inasmuch as both are types of replicating entities; thus, memes fit in with the picture of evolution drawn from biology. Although Dennett recognizes some differences, the connections are weak since the fundamental differences between memes and genes , such as their defining u ...
... between memes and genes inasmuch as both are types of replicating entities; thus, memes fit in with the picture of evolution drawn from biology. Although Dennett recognizes some differences, the connections are weak since the fundamental differences between memes and genes , such as their defining u ...
Lab 3 Procedure
... Meiosis cell division produces cells that are different from the original cell, increasing genetic variation in the population. Each diploid cell undergoing meiosis can produce 2n different chromosomal combinations, where n is the haploid number. In humans, n = 23. Thus humans can produce 223 or ove ...
... Meiosis cell division produces cells that are different from the original cell, increasing genetic variation in the population. Each diploid cell undergoing meiosis can produce 2n different chromosomal combinations, where n is the haploid number. In humans, n = 23. Thus humans can produce 223 or ove ...
Microsynth GmbH
... approximately equal intensity throughout the entire sequence. The fragments can also show a different running behavior, leading to double peaks that are not congruently superposed, but slightly shifted from each other. Sometimes the second primer binding site of the target sequence differs in a few ...
... approximately equal intensity throughout the entire sequence. The fragments can also show a different running behavior, leading to double peaks that are not congruently superposed, but slightly shifted from each other. Sometimes the second primer binding site of the target sequence differs in a few ...
Trouble Shooting Guide
... approximately equal intensity throughout the entire sequence. The fragments can also show a different running behavior, leading to double peaks that are not congruently superposed, but slightly shifted from each other. Sometimes the second primer binding site of the target sequence differs in a few ...
... approximately equal intensity throughout the entire sequence. The fragments can also show a different running behavior, leading to double peaks that are not congruently superposed, but slightly shifted from each other. Sometimes the second primer binding site of the target sequence differs in a few ...
File
... An affected female will pass the trait to all her sons Daughters will be carriers if father is not affected Males cannot be carriers (only have one X so either affected or not) More males than females affected (males inherit affected X from mother) ...
... An affected female will pass the trait to all her sons Daughters will be carriers if father is not affected Males cannot be carriers (only have one X so either affected or not) More males than females affected (males inherit affected X from mother) ...
Molecular Evidence for Vector Implication of Onchocerca lupi in Los
... The nodules are primarily composed of eosinophils, histiocytes, fibroblasts, and newly formed blood vessels (Zarfoss, Dubielzig, Eberhard, & Schmidt, 2005). This is typically associated with exophthalmos and possible third-eyelid protrusion (Komnenou, Egyed, Sréter, & Eberhard, 2003). In almost all ...
... The nodules are primarily composed of eosinophils, histiocytes, fibroblasts, and newly formed blood vessels (Zarfoss, Dubielzig, Eberhard, & Schmidt, 2005). This is typically associated with exophthalmos and possible third-eyelid protrusion (Komnenou, Egyed, Sréter, & Eberhard, 2003). In almost all ...
Requirements for Human Medical Genome
... The National Pathology Accreditation Advisory Council (NPAAC) was established in 1979 to advise the Australian, State and Territory governments on matters relating to the accreditation of pathology laboratories. A key role of NPAAC is to develop and maintain pathology quality standards for accredit ...
... The National Pathology Accreditation Advisory Council (NPAAC) was established in 1979 to advise the Australian, State and Territory governments on matters relating to the accreditation of pathology laboratories. A key role of NPAAC is to develop and maintain pathology quality standards for accredit ...
Progress in the Understanding of the Genetic Etiology of Vertebral
... and normal intelligence and cognitive performance are noted. The Role of DLL3 in Notch Signaling DLL3 is a DSL ligand of Notch that was originally isolated following recognition of its expression in the mesoderm and primitive streak during mouse gastrulation.28 Of the three delta-like ligands in mam ...
... and normal intelligence and cognitive performance are noted. The Role of DLL3 in Notch Signaling DLL3 is a DSL ligand of Notch that was originally isolated following recognition of its expression in the mesoderm and primitive streak during mouse gastrulation.28 Of the three delta-like ligands in mam ...
The somatic-visceral subdivision of the embryonic mesoderm is
... protein corresponds to the 2xPE-sna fusion gene (Fig. 2C). The distribution of sna mRNAs was visualized by in situ hybridization using a digoxigenin-labeled sna antisense RNA probe. As predicted from previous analyses of the PE promoter sequence (Jiang et al., 1991; Jiang and Levine, 1993), the synt ...
... protein corresponds to the 2xPE-sna fusion gene (Fig. 2C). The distribution of sna mRNAs was visualized by in situ hybridization using a digoxigenin-labeled sna antisense RNA probe. As predicted from previous analyses of the PE promoter sequence (Jiang et al., 1991; Jiang and Levine, 1993), the synt ...
ppt
... IV. Variation in Quantitative Traits A. Quantitative Effects B. Partitioning Variance C. Selection on Quantitative Traits - Traits affected by many genes have a higher probability of including a pleiotrophic gene – a gene that affects more than one trait. So, we might expect complex, quantitative tr ...
... IV. Variation in Quantitative Traits A. Quantitative Effects B. Partitioning Variance C. Selection on Quantitative Traits - Traits affected by many genes have a higher probability of including a pleiotrophic gene – a gene that affects more than one trait. So, we might expect complex, quantitative tr ...
- SciTech Connect
... Some of the earliest support for RNA-based transgenerational epigenetic inheritance comes from research in several plant systems. In contrast to animals, plants do not sequester the germline early in development; rather, at a specified time during its life, the plant switches from vegetative growth ...
... Some of the earliest support for RNA-based transgenerational epigenetic inheritance comes from research in several plant systems. In contrast to animals, plants do not sequester the germline early in development; rather, at a specified time during its life, the plant switches from vegetative growth ...
thalassemia
... • The severity of the disease depends on the nature of the mutation. Mutations are characterized as either βo or β thalassemia major if they prevent any formation of β chains, the most severe form of β thalassemia. Also, they are characterized as β+ or β thalassemia intermedia if they allow some β c ...
... • The severity of the disease depends on the nature of the mutation. Mutations are characterized as either βo or β thalassemia major if they prevent any formation of β chains, the most severe form of β thalassemia. Also, they are characterized as β+ or β thalassemia intermedia if they allow some β c ...
Ch. 15 Chromosomal Basis of Inheritance
... same chromosome, tend to move together through meiosis and fertilization. • Under normal Mendelian genetic rules, we would not expect linked genes to recombine into assortments of alleles not found in the parents. • If the seed color and seed coat genes were linked, we would expect the F1 offspring ...
... same chromosome, tend to move together through meiosis and fertilization. • Under normal Mendelian genetic rules, we would not expect linked genes to recombine into assortments of alleles not found in the parents. • If the seed color and seed coat genes were linked, we would expect the F1 offspring ...
Site-specific recombinase technology

Nearly every human gene has a counterpart in the mouse (regardless of the fact that a minor set of orthologues had to follow species specific selection routes). This made the mouse the major model for elucidating the ways in which our genetic material encodes information. In the late 1980s gene targeting in murine embryonic stem (ES-)cells enabled the transmission of mutations into the mouse germ line and emerged as a novel option to study the genetic basis of regulatory networks as they exist in the genome. Still, classical gene targeting proved to be limited in several ways as gene functions became irreversibly destroyed by the marker gene that had to be introduced for selecting recombinant ES cells. These early steps led to animals in which the mutation was present in all cells of the body from the beginning leading to complex phenotypes and/or early lethality. There was a clear need for methods to restrict these mutations to specific points in development and specific cell types. This dream became reality when groups in the USA were able to introduce bacteriophage and yeast-derived site-specific recombination (SSR-) systems into mammalian cells as well as into the mouse