Phylogenetic ANOVA: The Expression Variance and
... bioRxiv preprint first posted online Apr. 21, 2014; doi: http://dx.doi.org/10.1101/004374. The copyright holder for this preprint (which was not peer-reviewed) is the author/funder. It is made available under a CC-BY-NC-ND 4.0 International license. ...
... bioRxiv preprint first posted online Apr. 21, 2014; doi: http://dx.doi.org/10.1101/004374. The copyright holder for this preprint (which was not peer-reviewed) is the author/funder. It is made available under a CC-BY-NC-ND 4.0 International license. ...
CHAPTER 14 MENDEL AND THE GENE IDEA
... When sperm with four classes of alleles and ova with four classes of alleles combine, there are 16 equally probable ways in which the alleles can combine in the F 2 generation. ...
... When sperm with four classes of alleles and ova with four classes of alleles combine, there are 16 equally probable ways in which the alleles can combine in the F 2 generation. ...
How to use helper strains for maintaining and crossing handicapped... and resolving heterokaryons, and for determining heterokaryon compatibility.
... Mutant strains are often handicapped in various ways, manifested as sterility, slow growth, lack of conidia, poor viability, or instability (Barry 1992, Perkins 1986, Perkins 1993). Strains that do not conidiate are difficult to preserve, either on silica gel, by lyophylization, or by freezing. Howe ...
... Mutant strains are often handicapped in various ways, manifested as sterility, slow growth, lack of conidia, poor viability, or instability (Barry 1992, Perkins 1986, Perkins 1993). Strains that do not conidiate are difficult to preserve, either on silica gel, by lyophylization, or by freezing. Howe ...
Gene density and transcription influence the localization of
... 11p15.5 was linked to the imprinted state of genes in this region, as both alleles were found outside of chromosome territories in many nuclei. However, we wished to determine whether other imprinted regions of the human genome were also located outside of chromosome territories. There is a large cl ...
... 11p15.5 was linked to the imprinted state of genes in this region, as both alleles were found outside of chromosome territories in many nuclei. However, we wished to determine whether other imprinted regions of the human genome were also located outside of chromosome territories. There is a large cl ...
Cloning and Functional Studies of a Splice Variant of
... transfecting COS-1 cells with either full length or spliced CYP26B1 expression constructs, a combination of both, or the corresponding empty vector pcDNA3.2/V5-DEST, together with RARE-SEAP and control luciferase vectors. The results show that the CYP26B1 full length version reduced the RARE-regulat ...
... transfecting COS-1 cells with either full length or spliced CYP26B1 expression constructs, a combination of both, or the corresponding empty vector pcDNA3.2/V5-DEST, together with RARE-SEAP and control luciferase vectors. The results show that the CYP26B1 full length version reduced the RARE-regulat ...
chapter 6
... nevoid basal cell carcinoma syndrome {818}. This syndrome is caused by mutations in the tumour suppressor gene PTCH {524,866,1043}. PTCH encodes an inhibitory receptor in the sonic hedgehog signaling pathway, and germline mutations often lead to protein truncation and functional inactivation {2264}. ...
... nevoid basal cell carcinoma syndrome {818}. This syndrome is caused by mutations in the tumour suppressor gene PTCH {524,866,1043}. PTCH encodes an inhibitory receptor in the sonic hedgehog signaling pathway, and germline mutations often lead to protein truncation and functional inactivation {2264}. ...
Peter Kunzmann Metaphors in the Language of Darwinism
... to the Neodarwinians’ Gospel. Dawkins’ more or less figurative variations can almost serve as model metaphors. David Holdcroft and Harry Lewis wrote „It is common in the history of science to try to extend an idea first demonstrated in one domain into others. Sometimes the ex tension is literal, an ...
... to the Neodarwinians’ Gospel. Dawkins’ more or less figurative variations can almost serve as model metaphors. David Holdcroft and Harry Lewis wrote „It is common in the history of science to try to extend an idea first demonstrated in one domain into others. Sometimes the ex tension is literal, an ...
How imprinting is relevant to human disease - Development
... of chromosomes but both copies of a particular chromosome or chromosome segment have been derived from one or the other parent. At least seven mouse chromosome segments appear to have major differential effects on growth, behaviour and survival depending on whether inheritance is from the mother or ...
... of chromosomes but both copies of a particular chromosome or chromosome segment have been derived from one or the other parent. At least seven mouse chromosome segments appear to have major differential effects on growth, behaviour and survival depending on whether inheritance is from the mother or ...
Chromosome Analysis Suite 3.1 (ChAS 3.1)
... on separations between the normal reference and mutant calls that resulted in 95% sensitivity and 99% specificity (for lower confidence) and 95% sensitivity and 99.9% specificity (for high confidence) in our spike in experiments. The software provides for visualization of mutant probes versus refere ...
... on separations between the normal reference and mutant calls that resulted in 95% sensitivity and 99% specificity (for lower confidence) and 95% sensitivity and 99.9% specificity (for high confidence) in our spike in experiments. The software provides for visualization of mutant probes versus refere ...
The Optimal Discovery Procedure II: Applications to Comparative
... Abstract: As much of the focus of genetics and molecular biology has shifted toward the systems level, it has become increasingly important to accurately extract biologically relevant signal from thousands of related measurements. The common property among these high-dimensional biological studies i ...
... Abstract: As much of the focus of genetics and molecular biology has shifted toward the systems level, it has become increasingly important to accurately extract biologically relevant signal from thousands of related measurements. The common property among these high-dimensional biological studies i ...
The complement C3 protein family in invertebrates
... Hydrozoa, contained only A2M subfamily member (Miller et al., 2007). These results indicate that the creation of the TEP genes and subsequent gene duplication and functional differentiation into C3, A2M and CD109 have occurred in a relatively short evolutionary period after the divergence of sponges ...
... Hydrozoa, contained only A2M subfamily member (Miller et al., 2007). These results indicate that the creation of the TEP genes and subsequent gene duplication and functional differentiation into C3, A2M and CD109 have occurred in a relatively short evolutionary period after the divergence of sponges ...
Effects of cadmium on the regulation of antioxidant enzyme activity
... ABSTRACT. This study examined the antioxidative responses of the marine macroalga Ulva fasciata Delile to cadmium (Cd) stress. Exposure to 0, 5, 10, 20 and 50 µM CdCl2 for 4 days did not affect growth, 2,3,5-tri phenyltetrazolium chloride reduction ability, H2O2 production, or lipid peroxidation. Th ...
... ABSTRACT. This study examined the antioxidative responses of the marine macroalga Ulva fasciata Delile to cadmium (Cd) stress. Exposure to 0, 5, 10, 20 and 50 µM CdCl2 for 4 days did not affect growth, 2,3,5-tri phenyltetrazolium chloride reduction ability, H2O2 production, or lipid peroxidation. Th ...
Glioma heterogeneity and the LAT-1
... Glioma heterogeneity and the L-Amino acid transporter-1 (LAT1): A first step to stratified BPA-based BNCT? ...
... Glioma heterogeneity and the L-Amino acid transporter-1 (LAT1): A first step to stratified BPA-based BNCT? ...
4 Mapping Eukaryotic Chromosomes by
... crossovers at various locations along the chromosome. There are five total crossovers in the A-C region of this chromosome. One crossover occurs in the A-B region, for a frequency of 0.20. Four crossovers (two singles and a threestranded double) occur in the B-C region for a frequency of 0.80. Becau ...
... crossovers at various locations along the chromosome. There are five total crossovers in the A-C region of this chromosome. One crossover occurs in the A-B region, for a frequency of 0.20. Four crossovers (two singles and a threestranded double) occur in the B-C region for a frequency of 0.80. Becau ...
splicing.pdf
... This is just a preview, you will explore some of these different uses in more detail in the activity that follows. • In the example above, alternative splicing was used to include only one of several versions of an exon into a final protein product. This allows many slightly different versions of th ...
... This is just a preview, you will explore some of these different uses in more detail in the activity that follows. • In the example above, alternative splicing was used to include only one of several versions of an exon into a final protein product. This allows many slightly different versions of th ...
Nucleotide sequence and taxonomic value of the
... 'distance' between pairs of species from DNA sequences which are then utilized by the distance matrix programs FITCH and KITSCH. Sequences were first aligned with the multiple alignment program CLUSTAL (Higgins & Sharp, 1988) so that they contained the same number of characters including padding cha ...
... 'distance' between pairs of species from DNA sequences which are then utilized by the distance matrix programs FITCH and KITSCH. Sequences were first aligned with the multiple alignment program CLUSTAL (Higgins & Sharp, 1988) so that they contained the same number of characters including padding cha ...
Activity Name - Science4Inquiry.com
... Something Old, Something New… You are a Molecular Biologist who is studying the process of DNA replication. Your task is to build a model that represents this process. Next you will investigate where DNA replication took place in the human body and explain why it occurred. This activity is divided u ...
... Something Old, Something New… You are a Molecular Biologist who is studying the process of DNA replication. Your task is to build a model that represents this process. Next you will investigate where DNA replication took place in the human body and explain why it occurred. This activity is divided u ...
The Chromosomal Basis of Inheritance
... these imaginary units. Even after chromosomes were first observed, many biologists remained skeptical about Mendel’s laws of segregation and independent assortment until there was sufficient evidence that these principles of heredity had a physical basis in chromosomal behavior. Today, we know that ge ...
... these imaginary units. Even after chromosomes were first observed, many biologists remained skeptical about Mendel’s laws of segregation and independent assortment until there was sufficient evidence that these principles of heredity had a physical basis in chromosomal behavior. Today, we know that ge ...
chapter 14 mendel and the gene idea
... When sperm with four classes of alleles and ova with four classes of alleles combine, there are 16 equally probable ways in which the alleles can combine in the F2 generation. ...
... When sperm with four classes of alleles and ova with four classes of alleles combine, there are 16 equally probable ways in which the alleles can combine in the F2 generation. ...
werribee secondary college vce unit planner ~ 2004
... Thursday: major trends in hominin evolution from the genus Australopithecus to Homo including morphological, structural and cognitive development resulting in cultural evolution and the rise of technologies Friday: contd. And SAC 4 preparation Monday: SAC 4An oral or written report that demonstrated ...
... Thursday: major trends in hominin evolution from the genus Australopithecus to Homo including morphological, structural and cognitive development resulting in cultural evolution and the rise of technologies Friday: contd. And SAC 4 preparation Monday: SAC 4An oral or written report that demonstrated ...
EMBL-EBI Powerpoint Presentation
... pathway that supplies reducing energy to cells by maintaining the level of the co-enzyme nicotinamide adenine dinucleotide phosphate (NADPH). ...
... pathway that supplies reducing energy to cells by maintaining the level of the co-enzyme nicotinamide adenine dinucleotide phosphate (NADPH). ...
Site-specific recombinase technology
Nearly every human gene has a counterpart in the mouse (regardless of the fact that a minor set of orthologues had to follow species specific selection routes). This made the mouse the major model for elucidating the ways in which our genetic material encodes information. In the late 1980s gene targeting in murine embryonic stem (ES-)cells enabled the transmission of mutations into the mouse germ line and emerged as a novel option to study the genetic basis of regulatory networks as they exist in the genome. Still, classical gene targeting proved to be limited in several ways as gene functions became irreversibly destroyed by the marker gene that had to be introduced for selecting recombinant ES cells. These early steps led to animals in which the mutation was present in all cells of the body from the beginning leading to complex phenotypes and/or early lethality. There was a clear need for methods to restrict these mutations to specific points in development and specific cell types. This dream became reality when groups in the USA were able to introduce bacteriophage and yeast-derived site-specific recombination (SSR-) systems into mammalian cells as well as into the mouse