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Unit 4 – Soil Science
Unit 4 – Soil Science

... _____________________________an important process in meiosis leading to different genetic combinations in sex cells ...
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Biol.30-Unit I-Objectives - Science-with

... replication of DNA, a cell is able to undergo the process of reproduction. In this process one cell divides to form two new cells. Depending on the tissue in which it occurs and the reason for the cell division, the process is either mitosis or meiosis DNA contains genetic information that controls ...
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... recombination. Using chromosomes that had cytologically visible abnormalities, Creighton and McClintock working with maize, and Stern, working with Drosophila, showed that recombination depends upon the physical exchange of equal parts between maternal and paternal chromosomes during meiosis. Both g ...
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The α-globin gene cluster: genetics and disorders

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... through single mutated gene have been characterized Maps of human genomes permitted localization to chromosomal regions of over 400 of disease genes ...
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Molecular_Genetic_Characterization[1]

... The 2005 project had two major objectives to be accomplished under the $2000 award. The first was to identify the orthologs of photoperiod genes in Fragaria. The goal would be met starting with sequence from the model system. Using a series of methods, namely degenerate PCR and colony hybridization ...
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Genes required for B cell development

... were expressed in white blood cells from the patient, the authors interpret their results as indicating that the mutation had a dominant-suppressor effect on B cell development (24). It is interesting to speculate on how this dominant effect might occur and whether there might be other patients with ...
y 1
y 1

... “Mutation” of a gene might be due to changes elsewhere! •ald is Drosophila mps1 homolog; isolated four mutations (all rescued by ald+ transgene) •two ald alleles cause meiotic and mitotic defects (ald sequence changes) •two ald “mutations” cause only meiotic defects (normal ald sequence) •both cont ...
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Site-specific recombinase technology



Nearly every human gene has a counterpart in the mouse (regardless of the fact that a minor set of orthologues had to follow species specific selection routes). This made the mouse the major model for elucidating the ways in which our genetic material encodes information. In the late 1980s gene targeting in murine embryonic stem (ES-)cells enabled the transmission of mutations into the mouse germ line and emerged as a novel option to study the genetic basis of regulatory networks as they exist in the genome. Still, classical gene targeting proved to be limited in several ways as gene functions became irreversibly destroyed by the marker gene that had to be introduced for selecting recombinant ES cells. These early steps led to animals in which the mutation was present in all cells of the body from the beginning leading to complex phenotypes and/or early lethality. There was a clear need for methods to restrict these mutations to specific points in development and specific cell types. This dream became reality when groups in the USA were able to introduce bacteriophage and yeast-derived site-specific recombination (SSR-) systems into mammalian cells as well as into the mouse
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