Costimulatory receptors in jawed vertebrates: Conserved
... (V-LIKE-domain), a connecting region, a transmembrane region and an intracytoplasmic region. A conserved ligand-binding site in the FG loop (CDR3 equivalent) of the V-LIKE-DOMAIN of both molecules suggests that these receptors recognize B7 homologs as found for their mammalian counterparts. The intr ...
... (V-LIKE-domain), a connecting region, a transmembrane region and an intracytoplasmic region. A conserved ligand-binding site in the FG loop (CDR3 equivalent) of the V-LIKE-DOMAIN of both molecules suggests that these receptors recognize B7 homologs as found for their mammalian counterparts. The intr ...
Striking pattern of Purkinje cell loss in cerebellum of an ataxic
... Tottering mouse is an ataxic mutant that carries a mutation in a gene encoding for the α1A subunit of P/Q-type Ca2+ channel (Cav2.1). This study revisited to examine whether a Purkinje cell loss occurred in the cerebellum of tottering mice. In tottering mice, Calbindin D-28k negative gaps were appar ...
... Tottering mouse is an ataxic mutant that carries a mutation in a gene encoding for the α1A subunit of P/Q-type Ca2+ channel (Cav2.1). This study revisited to examine whether a Purkinje cell loss occurred in the cerebellum of tottering mice. In tottering mice, Calbindin D-28k negative gaps were appar ...
genetics - Krishikosh
... -;eneticists who lectured in this series. For each of their lectures I have provided a chapter containing a ist of readings, a set of notes, and questions for discussion. At intervals a number of tests also are in~luded, each covering the material in a group of chapters. While these contents could f ...
... -;eneticists who lectured in this series. For each of their lectures I have provided a chapter containing a ist of readings, a set of notes, and questions for discussion. At intervals a number of tests also are in~luded, each covering the material in a group of chapters. While these contents could f ...
Multiple Endocrine Neoplasia Type 1 and Lipomas
... Another question that various studies have examined is whether genetic chromosomal abnormalities similar to those responsible for MEN 1 cause lipomas and other lipomatous tumors. In a published report from 1995 by the Chromosomes and Morphology Collaborative Study Group (Table 2), Fletcher and colle ...
... Another question that various studies have examined is whether genetic chromosomal abnormalities similar to those responsible for MEN 1 cause lipomas and other lipomatous tumors. In a published report from 1995 by the Chromosomes and Morphology Collaborative Study Group (Table 2), Fletcher and colle ...
document
... Brown midrib (BMR) corn varieties have a natural mutation that results in low lignin in their cell walls, leading to increased digestibility, which is a highly desirable trait for silage maize production. Based on the sequence information from the public database, we designed oligos to amplify the C ...
... Brown midrib (BMR) corn varieties have a natural mutation that results in low lignin in their cell walls, leading to increased digestibility, which is a highly desirable trait for silage maize production. Based on the sequence information from the public database, we designed oligos to amplify the C ...
Concordance trees, concordance factors, and the exploration of
... data for a number of loci for a set of individuals representative of the taxa under study. If we are prepared to make some assumptions about the nature of populations and genetic processes, these data contain information on the history of the populations from which they are drawn. Therefore, the ide ...
... data for a number of loci for a set of individuals representative of the taxa under study. If we are prepared to make some assumptions about the nature of populations and genetic processes, these data contain information on the history of the populations from which they are drawn. Therefore, the ide ...
Systematic and Applied Microbiology - digital
... Results and discussion These sequences of strains BIFI-56 and BIFI-58 showed a 100% identity to the same fragment of the16S rRNA sequence from the E. faecium type strain (ATCC 19434, DSM 20477).Therefore the 16S rRNA sequence revealed that both strains were E. faecium isolates. In order to know if ...
... Results and discussion These sequences of strains BIFI-56 and BIFI-58 showed a 100% identity to the same fragment of the16S rRNA sequence from the E. faecium type strain (ATCC 19434, DSM 20477).Therefore the 16S rRNA sequence revealed that both strains were E. faecium isolates. In order to know if ...
Table of Contents - Scholars` Bank
... composed of smaller molecules, called amino acids, that link together and fold into a certain shape that dictates the protein’s function. The process of protein formation begins with a cell's database, its DNA. DNA stores information concerning how a cell functions and about the proteins needed to c ...
... composed of smaller molecules, called amino acids, that link together and fold into a certain shape that dictates the protein’s function. The process of protein formation begins with a cell's database, its DNA. DNA stores information concerning how a cell functions and about the proteins needed to c ...
TEXT Definition Chromosomal alterations are variations from the
... chromosome regions may be separated from one another, or may be adjacent. Large duplications of chromosomal material lead to gene imbalances that may be lethal to a zygote or even, in the case of plants, to the pollen or ovules that carry hem. Duplications in which the duplicated copies lie at diffe ...
... chromosome regions may be separated from one another, or may be adjacent. Large duplications of chromosomal material lead to gene imbalances that may be lethal to a zygote or even, in the case of plants, to the pollen or ovules that carry hem. Duplications in which the duplicated copies lie at diffe ...
Cytoplasmic male sterility
... not set any seed under bags. However, female fertility is evidently complete, since routine hand-pollinations with cv. Adorra for backcrosses resulted in a 95.9% seed set in 1078 florets of 50 spikes. In spikes under bags, partial fertility in the F1 hybrid 79BS14-3/Adorra was also found in the 1981 ...
... not set any seed under bags. However, female fertility is evidently complete, since routine hand-pollinations with cv. Adorra for backcrosses resulted in a 95.9% seed set in 1078 florets of 50 spikes. In spikes under bags, partial fertility in the F1 hybrid 79BS14-3/Adorra was also found in the 1981 ...
Structural changes following the reversal of a Y chromosome to an
... bioRxiv preprint first posted online Jun. 11, 2016; doi: http://dx.doi.org/10.1101/058412. The copyright holder for this preprint (which was not peer-reviewed) is the author/funder. It is made available under a CC-BY-NC-ND 4.0 International license. ...
... bioRxiv preprint first posted online Jun. 11, 2016; doi: http://dx.doi.org/10.1101/058412. The copyright holder for this preprint (which was not peer-reviewed) is the author/funder. It is made available under a CC-BY-NC-ND 4.0 International license. ...
Chromosome numbers in female and male gametes: One
... doubling may be compared with those derived from G1, LghA,/gl, lgaal heterozygotes (RHOADESand DEMPSEY 1966) where the Gl-Lg interval is comparable to the centromere-Lg segment in the elongate material. Data from plants with knobless chromosomes 3 gave the following frequencies: no exchange tetrads ...
... doubling may be compared with those derived from G1, LghA,/gl, lgaal heterozygotes (RHOADESand DEMPSEY 1966) where the Gl-Lg interval is comparable to the centromere-Lg segment in the elongate material. Data from plants with knobless chromosomes 3 gave the following frequencies: no exchange tetrads ...
Gekko 4_1 July 29
... information about the mechanism of albinism in other species. There may be some similarity between the tyrosinase positive albinism in leopard geckos, for example, and several human and murine forms of oculocutaneous albinism, an assortment of disorders that result in reduced or no melanin productio ...
... information about the mechanism of albinism in other species. There may be some similarity between the tyrosinase positive albinism in leopard geckos, for example, and several human and murine forms of oculocutaneous albinism, an assortment of disorders that result in reduced or no melanin productio ...
s_Proposal$AD_PDUseCase_05Feb07
... oligomers with dementing activity, with molecular composition of 3-24 monomeric subunits RS: The prominent immunoreactive species in soluble AD brain extracts thus was identified as an Abeta 12mer RS: Properties of ADDL in human ...
... oligomers with dementing activity, with molecular composition of 3-24 monomeric subunits RS: The prominent immunoreactive species in soluble AD brain extracts thus was identified as an Abeta 12mer RS: Properties of ADDL in human ...
Journal of Bacteriology
... PCL1171, was selected for study of the molecular basis of phase variation. In this strain, antagonistic activity, morphology, and expression of secondary metabolites (such as a lipopeptide with antifungal activity), biosurfactant activity, and the exoenzymes chitinase, lipase, and protease are regul ...
... PCL1171, was selected for study of the molecular basis of phase variation. In this strain, antagonistic activity, morphology, and expression of secondary metabolites (such as a lipopeptide with antifungal activity), biosurfactant activity, and the exoenzymes chitinase, lipase, and protease are regul ...
Microsoft Word (Chapter 3) - DORAS
... Figure 3.9: TonB Region III Motif. Black indicates 100% conservation, dark grey indicates 83% conservation and light grey indicates 66% conservation. ...
... Figure 3.9: TonB Region III Motif. Black indicates 100% conservation, dark grey indicates 83% conservation and light grey indicates 66% conservation. ...
Mechanisms and constraints shaping the evolution of body plan
... while in genome-based models transcription factor binding sites and genes encoding transcription factors (TFs) may evolve independently. When network-based models are combined with an initially small number of genes, this introduces a bias towards evolving interactions between genes present early du ...
... while in genome-based models transcription factor binding sites and genes encoding transcription factors (TFs) may evolve independently. When network-based models are combined with an initially small number of genes, this introduces a bias towards evolving interactions between genes present early du ...
Plant centromeres: structure and control Eric J Richards and R Kelly
... the highly reiterated centromere repeats in non-yeast systems. Are these repeats excess baggage surrounding rare functional centromeric sequence motifs or are the repeats an integral part of the centromere, perhaps the CEN DNA itself? Work in mammals has provided evidence for both points of view. A ...
... the highly reiterated centromere repeats in non-yeast systems. Are these repeats excess baggage surrounding rare functional centromeric sequence motifs or are the repeats an integral part of the centromere, perhaps the CEN DNA itself? Work in mammals has provided evidence for both points of view. A ...
PDF
... complement the homoeotic phenotype of trx1, as well as each others lethality. Genetic analysis suggests that all three alleles abolish most, if not all, of the wildtype function of the trx locus (Ingham, 1981); in addition, there is some evidence that trx3 may have an antimorphic component (unpublis ...
... complement the homoeotic phenotype of trx1, as well as each others lethality. Genetic analysis suggests that all three alleles abolish most, if not all, of the wildtype function of the trx locus (Ingham, 1981); in addition, there is some evidence that trx3 may have an antimorphic component (unpublis ...
cimmyt - Syngenta Foundation
... longer term approach for Striga control. Mutator-containing families with Striga-free phenotypes have been identified and verified through stringent genetic and lab-based assays. CIMMYT is presently investigating further the potential value of those resistant alleles, both at the phenotypic and mole ...
... longer term approach for Striga control. Mutator-containing families with Striga-free phenotypes have been identified and verified through stringent genetic and lab-based assays. CIMMYT is presently investigating further the potential value of those resistant alleles, both at the phenotypic and mole ...
alignable - gobics.de: Department of Bioinformatics
... For each position x and each sequence Si exist an upper bound ub(x,i) and a lower bound lb(x,i) for residues y in Si that are alignable with x ...
... For each position x and each sequence Si exist an upper bound ub(x,i) and a lower bound lb(x,i) for residues y in Si that are alignable with x ...
Clustering Genes using Heterogeneous Data Sources
... Clustering of gene expression data is a standard exploratory technique used to identify closely related genes. Many other sources of data are also likely to be of great assistance in the analysis of gene expression data. Such sources include proteinprotein interaction data, transcription factor and ...
... Clustering of gene expression data is a standard exploratory technique used to identify closely related genes. Many other sources of data are also likely to be of great assistance in the analysis of gene expression data. Such sources include proteinprotein interaction data, transcription factor and ...
Epigenetic Control of Apomixis
... been reported to play a key role in gene expression through RNAdirected DNA methylation (RdDM) of genes as well as by inducing histone modifications. Methylated cytosine (5-mC) has been reported to be involved in many important biological processes, including movement of transposable elements (TEs), ...
... been reported to play a key role in gene expression through RNAdirected DNA methylation (RdDM) of genes as well as by inducing histone modifications. Methylated cytosine (5-mC) has been reported to be involved in many important biological processes, including movement of transposable elements (TEs), ...
WUS and STM in shoot meristem regulation
... Mannheim, Germany); for the sense probe, ML343 was linearized with XbaI and transcribed with T3 RNA polymerase (Promega; Madison, USA). For the KNAT2 antisense riboprobe, plasmid pCKI-30 (kindly provided by J. Traas) which contains the full-length KNAT2 cDNA was linearized with XhoI and transcribed ...
... Mannheim, Germany); for the sense probe, ML343 was linearized with XbaI and transcribed with T3 RNA polymerase (Promega; Madison, USA). For the KNAT2 antisense riboprobe, plasmid pCKI-30 (kindly provided by J. Traas) which contains the full-length KNAT2 cDNA was linearized with XhoI and transcribed ...
Site-specific recombinase technology
Nearly every human gene has a counterpart in the mouse (regardless of the fact that a minor set of orthologues had to follow species specific selection routes). This made the mouse the major model for elucidating the ways in which our genetic material encodes information. In the late 1980s gene targeting in murine embryonic stem (ES-)cells enabled the transmission of mutations into the mouse germ line and emerged as a novel option to study the genetic basis of regulatory networks as they exist in the genome. Still, classical gene targeting proved to be limited in several ways as gene functions became irreversibly destroyed by the marker gene that had to be introduced for selecting recombinant ES cells. These early steps led to animals in which the mutation was present in all cells of the body from the beginning leading to complex phenotypes and/or early lethality. There was a clear need for methods to restrict these mutations to specific points in development and specific cell types. This dream became reality when groups in the USA were able to introduce bacteriophage and yeast-derived site-specific recombination (SSR-) systems into mammalian cells as well as into the mouse