
Epigenetic Control of Apomixis
... been reported to play a key role in gene expression through RNAdirected DNA methylation (RdDM) of genes as well as by inducing histone modifications. Methylated cytosine (5-mC) has been reported to be involved in many important biological processes, including movement of transposable elements (TEs), ...
... been reported to play a key role in gene expression through RNAdirected DNA methylation (RdDM) of genes as well as by inducing histone modifications. Methylated cytosine (5-mC) has been reported to be involved in many important biological processes, including movement of transposable elements (TEs), ...
WUS and STM in shoot meristem regulation
... Mannheim, Germany); for the sense probe, ML343 was linearized with XbaI and transcribed with T3 RNA polymerase (Promega; Madison, USA). For the KNAT2 antisense riboprobe, plasmid pCKI-30 (kindly provided by J. Traas) which contains the full-length KNAT2 cDNA was linearized with XhoI and transcribed ...
... Mannheim, Germany); for the sense probe, ML343 was linearized with XbaI and transcribed with T3 RNA polymerase (Promega; Madison, USA). For the KNAT2 antisense riboprobe, plasmid pCKI-30 (kindly provided by J. Traas) which contains the full-length KNAT2 cDNA was linearized with XhoI and transcribed ...
Clustering Genes using Heterogeneous Data Sources
... Clustering of gene expression data is a standard exploratory technique used to identify closely related genes. Many other sources of data are also likely to be of great assistance in the analysis of gene expression data. Such sources include proteinprotein interaction data, transcription factor and ...
... Clustering of gene expression data is a standard exploratory technique used to identify closely related genes. Many other sources of data are also likely to be of great assistance in the analysis of gene expression data. Such sources include proteinprotein interaction data, transcription factor and ...
Gene Detection Systems Catalog
... sequencing, cloning, and mutagenesis. Gene Link services include genotyping, sequencing and gene construction. Gene Link offers as well a wide variety of other molecular biology products such as, siRNA, fluorescent probes and nonradioactive gene detection systems for human genetic disorders. Gene Li ...
... sequencing, cloning, and mutagenesis. Gene Link services include genotyping, sequencing and gene construction. Gene Link offers as well a wide variety of other molecular biology products such as, siRNA, fluorescent probes and nonradioactive gene detection systems for human genetic disorders. Gene Li ...
Prader-Willi and Angelman syndromes: Sister imprinted disorders
... to chromosome 15q11-q13. They both have characteristic neurologic, developmental, and behavioral phenotypes plus other structural and functional abnormalities. However, the cognitive and neurologic impairment is more severe in AS, including seizures and ataxia. The behavioral and endocrine disorders ...
... to chromosome 15q11-q13. They both have characteristic neurologic, developmental, and behavioral phenotypes plus other structural and functional abnormalities. However, the cognitive and neurologic impairment is more severe in AS, including seizures and ataxia. The behavioral and endocrine disorders ...
Chromosomal Basis of Inherited Disorders
... of functional challenges and often precludes development. The most common trisomy among viable births is that of chromosome 21, which corresponds to Down Syndrome. Individuals with this inherited disorder are characterized by short stature and stunted digits, facial distinctions that include a broad ...
... of functional challenges and often precludes development. The most common trisomy among viable births is that of chromosome 21, which corresponds to Down Syndrome. Individuals with this inherited disorder are characterized by short stature and stunted digits, facial distinctions that include a broad ...
Transcript
... versa, we’re actually changing more than just that one gene? [DOEBLEY:] That’s right, they can turn other genes on and off. You could think of these genes as something like the conductor of an orchestra. And if you would take the conductor from one orchestra and give that orchestra, say, a new condu ...
... versa, we’re actually changing more than just that one gene? [DOEBLEY:] That’s right, they can turn other genes on and off. You could think of these genes as something like the conductor of an orchestra. And if you would take the conductor from one orchestra and give that orchestra, say, a new condu ...
Slide 1
... • in the previous slide the evolutionarily stable strategy that we found is the one that maximised personal reproduction • but is it ever possible that animals do not strictly maximise their personal reproduction? • William Hamilton: yes, if interactions occur between relatives. In that case we need ...
... • in the previous slide the evolutionarily stable strategy that we found is the one that maximised personal reproduction • but is it ever possible that animals do not strictly maximise their personal reproduction? • William Hamilton: yes, if interactions occur between relatives. In that case we need ...
Exercise 11 - Understanding the Output for a blastn Search
... relative of the model fruit fly Drosophila melanogaster) contains region(s) with sequence similarity to any known genes. The unknown sequence is an 11,000 base pair (bp) fragment of genomic DNA, and the objective of gene annotation is to find and precisely map the coding regions of any genes in this ...
... relative of the model fruit fly Drosophila melanogaster) contains region(s) with sequence similarity to any known genes. The unknown sequence is an 11,000 base pair (bp) fragment of genomic DNA, and the objective of gene annotation is to find and precisely map the coding regions of any genes in this ...
BMC Bioinformatics
... referred to as linear transformations. In this work, we consider a subset of affine transformations that include all of the above operations except shearing.) registration using these landmarks. Although there are many differences in the details, the methods are similar in spirit. Another very simil ...
... referred to as linear transformations. In this work, we consider a subset of affine transformations that include all of the above operations except shearing.) registration using these landmarks. Although there are many differences in the details, the methods are similar in spirit. Another very simil ...
Disintegrin, hemorrhagic, and proteolytic activities of Mohave
... h. Snake venom fractions were added to the cell suspension at concentrations of 60 Ag/mL, and allowed to incubate at 37-C for 1 h. The fraction that showed disintegrin activity by inhibiting platelet aggregation was tested at various concentrations (134, 67, 33, 17, 8, and 4 Ag/mL). The blocking sol ...
... h. Snake venom fractions were added to the cell suspension at concentrations of 60 Ag/mL, and allowed to incubate at 37-C for 1 h. The fraction that showed disintegrin activity by inhibiting platelet aggregation was tested at various concentrations (134, 67, 33, 17, 8, and 4 Ag/mL). The blocking sol ...
org.Dr.eg.db
... gene identifier more than once but the evidence code can be different. Mappings between Gene Ontology identifiers and Gene Ontology terms and other information are available in a separate data package named GO. Whenever any of these mappings are cast as a data.frame, all the results will be output i ...
... gene identifier more than once but the evidence code can be different. Mappings between Gene Ontology identifiers and Gene Ontology terms and other information are available in a separate data package named GO. Whenever any of these mappings are cast as a data.frame, all the results will be output i ...
Genetic Transformation of Poinsettia (Euphórbia
... In nature, A. tumefaciens will infect dicotyledonous plants to produce crown-gall disease by transferring genes coding for crown-gall into the plant (Hoekema et al. 1983; Stachel & Nester 1986). This is done by a virulence region (vir-region) located in a tumour inducing plasmid (Tiplasmid) in the A ...
... In nature, A. tumefaciens will infect dicotyledonous plants to produce crown-gall disease by transferring genes coding for crown-gall into the plant (Hoekema et al. 1983; Stachel & Nester 1986). This is done by a virulence region (vir-region) located in a tumour inducing plasmid (Tiplasmid) in the A ...
Progress and promise in understanding the genetic
... Susceptibility to common human diseases is influenced by both genetic and environmental factors. The explosive growth of genetic data, and the knowledge that it is generating, are transforming our biological understanding of these diseases. In this review, we describe the technological and analytica ...
... Susceptibility to common human diseases is influenced by both genetic and environmental factors. The explosive growth of genetic data, and the knowledge that it is generating, are transforming our biological understanding of these diseases. In this review, we describe the technological and analytica ...
adapt1
... G. Species Selection - Parthenogenesis arises spontaneously, but extinctions are rapid due to lack of variation and Muller's rachet. Muller's ratchet is the continuous accumulation of mutations in a lineage. In sexual reproduction, since only 1/2 of the genes are passed from each parent, there is a ...
... G. Species Selection - Parthenogenesis arises spontaneously, but extinctions are rapid due to lack of variation and Muller's rachet. Muller's ratchet is the continuous accumulation of mutations in a lineage. In sexual reproduction, since only 1/2 of the genes are passed from each parent, there is a ...
Keratins and skin disorders
... Mutations in K5 or K14 cause epidermolysis bullosa simplex, in which the basal cells are fragile and may fracture if the epidermis is subjected to even quite mild physical trauma such as rubbing or scratching (Figure 3); this intraepidermal cytolysis of the basal keratinocyte cells leads to fluid-fi ...
... Mutations in K5 or K14 cause epidermolysis bullosa simplex, in which the basal cells are fragile and may fracture if the epidermis is subjected to even quite mild physical trauma such as rubbing or scratching (Figure 3); this intraepidermal cytolysis of the basal keratinocyte cells leads to fluid-fi ...
fulltext
... and the dehydrated state. It is known that these factors may cause damage to DNA. It has recently been shown that single and double DNA strand breaks occur when tardigrades are maintained for a long time in the anhydrobiotic state. This may suggest that perhaps tardigrades rely on efficient DNA repa ...
... and the dehydrated state. It is known that these factors may cause damage to DNA. It has recently been shown that single and double DNA strand breaks occur when tardigrades are maintained for a long time in the anhydrobiotic state. This may suggest that perhaps tardigrades rely on efficient DNA repa ...
December 2013 Newsletter - Wynnum Redlands Budgerigar Society
... similar composition and share the same locus. As a result, these two recessive expressions, when present in the one individual, combine to produce a composite effect. That composite is typically called a "fullbody-colored Greywing. The fact that the expression is termed a qualified "Greywing" is a m ...
... similar composition and share the same locus. As a result, these two recessive expressions, when present in the one individual, combine to produce a composite effect. That composite is typically called a "fullbody-colored Greywing. The fact that the expression is termed a qualified "Greywing" is a m ...
[Full text/PDF]
... of GPU and program performance optimization begin to be applied. The GMDR-GPU generates the SNP combinations in the CPU to take advantage of its fast sequential execution feature, while at the same time, it distributes the calculation of all the training accuracies for an SNP combination to one of t ...
... of GPU and program performance optimization begin to be applied. The GMDR-GPU generates the SNP combinations in the CPU to take advantage of its fast sequential execution feature, while at the same time, it distributes the calculation of all the training accuracies for an SNP combination to one of t ...
Ancient Structure in Africa Unlikely to Explain Neanderthal and Non
... from the three Vindija bones (SLVi33.16, SLVi33.25, and SLVi33.26) that were aligned to hg18 (Green et al. 2010). The Neanderthal data were downloaded from the UCSC genome browser (http://genome.ucsc.edu/Neandertal/) in May 2011. Following Green et al. (2010), we used only sites with a mapping quali ...
... from the three Vindija bones (SLVi33.16, SLVi33.25, and SLVi33.26) that were aligned to hg18 (Green et al. 2010). The Neanderthal data were downloaded from the UCSC genome browser (http://genome.ucsc.edu/Neandertal/) in May 2011. Following Green et al. (2010), we used only sites with a mapping quali ...
Mitotic recombination counteracts the benefits of
... Agrawal & Otto 2006) and the spread of modifier alleles altering the frequency of sex (Uyenoyama & Bengtsson 1989; Antezana & Hudson 1997b; Dolgin & Otto 2003; Otto 2003). Here, we return to Kirkpatrick & Jenkins’ (1989) original question: how does sex with the attendant segregation of chromosomes a ...
... Agrawal & Otto 2006) and the spread of modifier alleles altering the frequency of sex (Uyenoyama & Bengtsson 1989; Antezana & Hudson 1997b; Dolgin & Otto 2003; Otto 2003). Here, we return to Kirkpatrick & Jenkins’ (1989) original question: how does sex with the attendant segregation of chromosomes a ...
Site-specific recombinase technology

Nearly every human gene has a counterpart in the mouse (regardless of the fact that a minor set of orthologues had to follow species specific selection routes). This made the mouse the major model for elucidating the ways in which our genetic material encodes information. In the late 1980s gene targeting in murine embryonic stem (ES-)cells enabled the transmission of mutations into the mouse germ line and emerged as a novel option to study the genetic basis of regulatory networks as they exist in the genome. Still, classical gene targeting proved to be limited in several ways as gene functions became irreversibly destroyed by the marker gene that had to be introduced for selecting recombinant ES cells. These early steps led to animals in which the mutation was present in all cells of the body from the beginning leading to complex phenotypes and/or early lethality. There was a clear need for methods to restrict these mutations to specific points in development and specific cell types. This dream became reality when groups in the USA were able to introduce bacteriophage and yeast-derived site-specific recombination (SSR-) systems into mammalian cells as well as into the mouse