• Study Resource
  • Explore Categories
    • Arts & Humanities
    • Business
    • Engineering & Technology
    • Foreign Language
    • History
    • Math
    • Science
    • Social Science

    Top subcategories

    • Advanced Math
    • Algebra
    • Basic Math
    • Calculus
    • Geometry
    • Linear Algebra
    • Pre-Algebra
    • Pre-Calculus
    • Statistics And Probability
    • Trigonometry
    • other →

    Top subcategories

    • Astronomy
    • Astrophysics
    • Biology
    • Chemistry
    • Earth Science
    • Environmental Science
    • Health Science
    • Physics
    • other →

    Top subcategories

    • Anthropology
    • Law
    • Political Science
    • Psychology
    • Sociology
    • other →

    Top subcategories

    • Accounting
    • Economics
    • Finance
    • Management
    • other →

    Top subcategories

    • Aerospace Engineering
    • Bioengineering
    • Chemical Engineering
    • Civil Engineering
    • Computer Science
    • Electrical Engineering
    • Industrial Engineering
    • Mechanical Engineering
    • Web Design
    • other →

    Top subcategories

    • Architecture
    • Communications
    • English
    • Gender Studies
    • Music
    • Performing Arts
    • Philosophy
    • Religious Studies
    • Writing
    • other →

    Top subcategories

    • Ancient History
    • European History
    • US History
    • World History
    • other →

    Top subcategories

    • Croatian
    • Czech
    • Finnish
    • Greek
    • Hindi
    • Japanese
    • Korean
    • Persian
    • Swedish
    • Turkish
    • other →
 
Profile Documents Logout
Upload
U6 snRNA genes of Arabidopsis are transcribed
U6 snRNA genes of Arabidopsis are transcribed

... 5S rRNA genes containing internal A and B (or C) boxes are examples of such genes (2,5,6). In recent years, however, this distinction between pol II and pol in promoters has become much less rigid, (i) It has been found that efficient transcription of some tRNA and 5S rRNA genes (reviewed in ref. 2) ...
BIOL 107 Human Biology # 1 of 10 Units
BIOL 107 Human Biology # 1 of 10 Units

... genome gain and loss in vertebrates, DNA rapidly and tracing of evolutionary relationships with conserved sequences. ...
DNA and Gene Expression (chaps 12-15)
DNA and Gene Expression (chaps 12-15)

... In the experiments of Griffith, the conversion of nonlethal R-strain bacteria to lethal S-strain bacteria: A. was an example of conjugation. B. was the result of genetic mutation. C. was an example of the genetic exchange known as transformation. D. supported the case for proteins as the genetic mat ...
PDF file
PDF file

... thousands of loci (small frequency differences) Autosomal requires Z-Chromosome Mallard ( > 10 million) ...
Induction of the white egg3 mutant phenotype by injection of the
Induction of the white egg3 mutant phenotype by injection of the

... genes to determine whether the RNAi acts in the silkworm because these genes are expressed at the early stage of the embryonic development and the morphological changes can be easily observed. In addition, the function of the Bmwh3 gene is cell-autonomous, and the protein controls the transport of t ...
Nucleic Acids: Revisiting the Central Dogma
Nucleic Acids: Revisiting the Central Dogma

... The molecular hallmarks of lin-4, the founding member of the microRNA family. Sequence complementarity between lin-4 (red) and the 3'-untranslated region (UTR) of lin-14 mRNA (blue). lin-4 is partially complementary to 7 sites in the lin-14 3' UTR; its binding to these sites of complementarity bring ...
PDF
PDF

... shoot apical meristems of zwille mutants, although initiated correctly, do not undergo asymmetric divisions that give rise to repetitive organs along the vertical axis of the plant. Instead, the stem cells in the central zone of the meristem lose their stem cell character and terminally differentiat ...
PGRN-RIKEN Proposal Submission We are encouraging
PGRN-RIKEN Proposal Submission We are encouraging

... investigators who are studying drugs that have not been previously studied using genomewide approaches, or new phenotypes of drug response that have not been studied. Such phenotypes may include hard endpoints, e.g. rather than statin-associated change in LDL-cholesterol, a new phenotype might be ti ...
C2005/F2401 `07 -- Lecture 15 -- Last Edited
C2005/F2401 `07 -- Lecture 15 -- Last Edited

... b. Synthesis of repressor protein is constitutive -- gene is always on. (State of repressor protein varies, not the amount; see below.) Question: Does the gene for repressor protein have a promoter? an operator? C. How induction and repression occur -- Role of Effectors 1. Repressor protein is allos ...
The diagrams below show two different scenarios for a pair of
The diagrams below show two different scenarios for a pair of

... (C) Cell 1 is undergoing normal meiosis, whereas cell 2 is completing meiosis but with too many chromosomes because a pair of homologous chromosomes failed to separate and resulted in a trisomy. Distractor Rationale: This answer suggests the student may understand that meiosis results in production ...
Ramamoorthy, Krithika : Critical Review of Methods available for Microarray Data Analysis
Ramamoorthy, Krithika : Critical Review of Methods available for Microarray Data Analysis

... regression modeling. Nonparametric tests include Bayesian frameworks, mixed modeling approaches and simpler tests such as the Wilcoxon’s test, Mann-Whitney U test etc. These methods will not be reviewed in detailed here and are available elsewhere (5, 9-11). Supervised and unsupervised methods Super ...
RNA Processing
RNA Processing

... – Is determined in part by sequences in the leader and trailer regions ...
Methods of screening for bioactive agents using cells transformed
Methods of screening for bioactive agents using cells transformed

... for each cell type being analyZed due to inherent differences ...
Familial Lung Cancer Gene Located
Familial Lung Cancer Gene Located

Methemoglobinemia: What really is in the drinking water in
Methemoglobinemia: What really is in the drinking water in

... blue child contain some NADH diaphorase activity but not much. ...
Expanding Yeast Knowledge Online.
Expanding Yeast Knowledge Online.

... briefly summarize in tables. None of these descriptions is meant to be exhaustive. Instead, we highlight the general features and mention particularly useful or unique tools at each site, keeping in mind that these databases are constantly evolving. All URLs mentioned in this review can be obtained ...
ArrayExpress and Expression Atlas
ArrayExpress and Expression Atlas

... What is functional genomics (FG)? • The aim of FG is to understand the function of genes and other parts of the genome ...
Meiosis The main reason we have meiosis is for sexual reproduction
Meiosis The main reason we have meiosis is for sexual reproduction

... A chromosome may have a locus (“location”) that has a gene that codes for eye color. The homologous chromosome will also have a gene at the same locus that codes for eye color. BUT, the gene on one chromosome may say “blue eyes”, while the gene on the other chromosome may say “yellow eyes” (This is ...
Andreas Mock Cancer Research UK Cambridge Institute, University
Andreas Mock Cancer Research UK Cambridge Institute, University

... than a ‘hard’ threshold ττ. However, this hard threshold does not reflect the underlying continuous co-expression measure and leads to a significant loss of information. As a consequence, Horvath and colleagues introduced a new framework for weighted gene co-expression analysis (WGCNA)5. At its core ...
Contemporary, yeast-based approaches to
Contemporary, yeast-based approaches to

... mutations in a set of common orthologous genes. By taking advantage of phenologs, experimenters can derive nonobvious models for complex human disease in organisms like yeast. For example, a systematic hunt for orthologous human disease phenotypes in model organisms suggested a yeast model for angio ...
meiosis lab - EDHSGreenSea.net
meiosis lab - EDHSGreenSea.net

... In this example, crossing over has occurred in the region between the gene for spore color and the centromere. The homologous chromosomes separate during meiosis I. This time, the Meiosis I results in two cells, each containing both genes (1 tan, 1 wild-type); therefore, the genes for spore color ha ...
Workbook - The Campion School
Workbook - The Campion School

... An inhibitor is a substance which reduces the rate of an enzyme-catalysed reaction. Some inhibitors have a shape which is similar to the substrate and can fit into the active site, so blocking access for the substrate. The inhibitor may then leave the active site, so that the substrate is able to at ...
A Survey of Intron Research in Genetics
A Survey of Intron Research in Genetics

... The existence of the intron-exon structure has been particularly intriguing. Introns are only found in eukaryotic genomes and make up a large portion of the DNA in eukaryotic genomes. In humans, for example, approximately 30% of the human genome is made up of introns [1]. Only about 3% consists of c ...
Argonaute2 Is Essential for Mammalian
Argonaute2 Is Essential for Mammalian

... demonstrated that both transforming growth factor a and FGF signaling are required to initiate T expression as gastrulation commences [18,29,30]. In mice, mutational analysis of the known FGF genes established that only Fgf4 and Fgf8 are required during gastrulation [31,32]. Fgf4 and Fgf8 are coexpr ...
The silence of genes
The silence of genes

... seed that provides nutrients for the developing embryo. Once the seed germinates, the endosperm is discarded and imprinting has no effect on the growing plant. In Arabidopsis, for example, the paternal MEDEA gene, which suppresses endosperm growth, is imprinted in the endosperm but not in the embryo ...
< 1 ... 333 334 335 336 337 338 339 340 341 ... 1288 >

Site-specific recombinase technology



Nearly every human gene has a counterpart in the mouse (regardless of the fact that a minor set of orthologues had to follow species specific selection routes). This made the mouse the major model for elucidating the ways in which our genetic material encodes information. In the late 1980s gene targeting in murine embryonic stem (ES-)cells enabled the transmission of mutations into the mouse germ line and emerged as a novel option to study the genetic basis of regulatory networks as they exist in the genome. Still, classical gene targeting proved to be limited in several ways as gene functions became irreversibly destroyed by the marker gene that had to be introduced for selecting recombinant ES cells. These early steps led to animals in which the mutation was present in all cells of the body from the beginning leading to complex phenotypes and/or early lethality. There was a clear need for methods to restrict these mutations to specific points in development and specific cell types. This dream became reality when groups in the USA were able to introduce bacteriophage and yeast-derived site-specific recombination (SSR-) systems into mammalian cells as well as into the mouse
  • studyres.com © 2026
  • DMCA
  • Privacy
  • Terms
  • Report