
Recruitment of CRABS CLAW to promote nectary development
... perianth positions in basal taxa to central positions associated with reproductive organs in more derived taxa. In addition, extrafloral nectaries are currently known in 68 angiosperm families (Elias, 1983). Their structures and locations are also diverse across the families, although they occur mos ...
... perianth positions in basal taxa to central positions associated with reproductive organs in more derived taxa. In addition, extrafloral nectaries are currently known in 68 angiosperm families (Elias, 1983). Their structures and locations are also diverse across the families, although they occur mos ...
Characterisation of interstitial duplications and triplications of
... showed that, in all cases, the duplications and triplications involved the PWACR and were not pseudogene expansions. Retrospective cytogenetic analysis in families 7 and 13 did not identify these duplications clearly. The size of the pericentromeric area of 15q varies greatly within the normal popul ...
... showed that, in all cases, the duplications and triplications involved the PWACR and were not pseudogene expansions. Retrospective cytogenetic analysis in families 7 and 13 did not identify these duplications clearly. The size of the pericentromeric area of 15q varies greatly within the normal popul ...
Perspectives in Diabetes Glucokinase Gene Structure
... site between the first and second exons of the hepatic glucokinase transcription unit (12,25). This finding indicated that the hepatic and p-cell glucokinase transcription units utilized different first exons and therefore also utilized different transcription control regions. Figure 1 illustrates t ...
... site between the first and second exons of the hepatic glucokinase transcription unit (12,25). This finding indicated that the hepatic and p-cell glucokinase transcription units utilized different first exons and therefore also utilized different transcription control regions. Figure 1 illustrates t ...
hirota - Genetics
... transmissible Gal+ transductants derived from the rec+ recipient recovered gal+ transfer ability when R,,,~, was introduced. On the other hand, all of those derived from the rec- recipient recovered gal+ transfer ability when infected with RIO,-,. Thus the nontransmissible Gal+ transductants derived ...
... transmissible Gal+ transductants derived from the rec+ recipient recovered gal+ transfer ability when R,,,~, was introduced. On the other hand, all of those derived from the rec- recipient recovered gal+ transfer ability when infected with RIO,-,. Thus the nontransmissible Gal+ transductants derived ...
p53, the Cellular Gatekeeper Review for Growth and Division
... events or signals that flow to p53 are mediated by several stressful situations. Several different types of DNA damage can activate p53, including double-strand breaks in DNA produced by g-irradiation and the presence of DNA repair intermediates after ultraviolet irradiation or chemical damage to DN ...
... events or signals that flow to p53 are mediated by several stressful situations. Several different types of DNA damage can activate p53, including double-strand breaks in DNA produced by g-irradiation and the presence of DNA repair intermediates after ultraviolet irradiation or chemical damage to DN ...
Genetics - York University
... offspring that were not normal variations. The induced mutations were usually harmful, often fatal, but they also could be changes that would be beneficial. Thus mutations provide a possible path for evolution with natural selection. ...
... offspring that were not normal variations. The induced mutations were usually harmful, often fatal, but they also could be changes that would be beneficial. Thus mutations provide a possible path for evolution with natural selection. ...
Arabidopsis
... via root wounds or sites of secondary root emergence (Genin 2010). The bacteria spread toward the xylem vessels and colonize the root cortex and vascular parenchyma (Turner et al. 2009). R. solanacearum secretes copious amounts of extracellular products, resulting in cell damage. The accumulation of ...
... via root wounds or sites of secondary root emergence (Genin 2010). The bacteria spread toward the xylem vessels and colonize the root cortex and vascular parenchyma (Turner et al. 2009). R. solanacearum secretes copious amounts of extracellular products, resulting in cell damage. The accumulation of ...
(..rignt click_Save Target As..)
... crossover events common (eg, the recessive white gene assorts independently from the Pea Comb gene, as no linkage between their loci). For there to be a linkage between loci, they must be on the same homologous chromosome and in close proximity (less than 50 map units). Linked loci crossover less th ...
... crossover events common (eg, the recessive white gene assorts independently from the Pea Comb gene, as no linkage between their loci). For there to be a linkage between loci, they must be on the same homologous chromosome and in close proximity (less than 50 map units). Linked loci crossover less th ...
Table 3 - HAL Descartes
... Type IV Waardenburg syndrome (WS4, MIM_277580), also called ShahWaardenburg syndrome or Waardenburg-Hirschsprung disease, combines pigmentation defects, deafness and Hirschsprung disease 10. Mutations in EDNRB, encoding the endothelin B receptor (a G-protein coupled transmembrane receptor), and EDN3 ...
... Type IV Waardenburg syndrome (WS4, MIM_277580), also called ShahWaardenburg syndrome or Waardenburg-Hirschsprung disease, combines pigmentation defects, deafness and Hirschsprung disease 10. Mutations in EDNRB, encoding the endothelin B receptor (a G-protein coupled transmembrane receptor), and EDN3 ...
Ethanol exposure affects gene expression in the embryonic
... identified numerous genes active in this embryonic structure. Among the organizer-specific genes are transcription factors, growth factors and secreted proteins. It is known that the interactions between these organizer-specific genes and others expressed around the blastopore will determine many as ...
... identified numerous genes active in this embryonic structure. Among the organizer-specific genes are transcription factors, growth factors and secreted proteins. It is known that the interactions between these organizer-specific genes and others expressed around the blastopore will determine many as ...
Azole antifungals are potent inhibitors of cytochrome
... The CYP121 enzyme was produced in the T7 RNA polymerase lysogen strain HMS174 (DE3) (Novagen). Conditions used for CYP121 production were growth of HMS174 (DE3)(pKM2b) transformants at 30 mC in Terrific Broth (Sambrook et al., 1989) with vigorous agitation (250 r.p.m.) until the midexponential phase ...
... The CYP121 enzyme was produced in the T7 RNA polymerase lysogen strain HMS174 (DE3) (Novagen). Conditions used for CYP121 production were growth of HMS174 (DE3)(pKM2b) transformants at 30 mC in Terrific Broth (Sambrook et al., 1989) with vigorous agitation (250 r.p.m.) until the midexponential phase ...
Close - Journal of Integrated OMICS
... The Iberian lynx is a critically endangered species native of the Iberian Peninsula [5]. This species typically hunts the European wild rabbit (Oryctolagus cuniculus). The decline of prey population along with habitat loss caused a restriction in the Iberian lynx geographical distribution. Total wil ...
... The Iberian lynx is a critically endangered species native of the Iberian Peninsula [5]. This species typically hunts the European wild rabbit (Oryctolagus cuniculus). The decline of prey population along with habitat loss caused a restriction in the Iberian lynx geographical distribution. Total wil ...
Inclusive fitness and the sociobiology of the genome
... conditions ensure that the gene is selfish in the sense described by Dawkins (1976). In particular, Hamilton’s rule implies that the conditions for the evolutionary success of a gene are distinct from the conditions under which the gene enhances the mean fitness of the reproductive population. There ...
... conditions ensure that the gene is selfish in the sense described by Dawkins (1976). In particular, Hamilton’s rule implies that the conditions for the evolutionary success of a gene are distinct from the conditions under which the gene enhances the mean fitness of the reproductive population. There ...
Ribosomal proteins promote leaf adaxial identity
... panel) and 3 (B, upper panel), and AE5 (At2g19730) and AE6 (At3g25520) encode ribosomal proteins RPL28A (A, lower panel) and RPL5A (B, lower panel), respectively. Black and white boxes indicate the protein-coding region and untranslational region (UTR), respectively. (C) RT-PCR shows that AE5 and AE ...
... panel) and 3 (B, upper panel), and AE5 (At2g19730) and AE6 (At3g25520) encode ribosomal proteins RPL28A (A, lower panel) and RPL5A (B, lower panel), respectively. Black and white boxes indicate the protein-coding region and untranslational region (UTR), respectively. (C) RT-PCR shows that AE5 and AE ...
Classification of Centers for Disease Control Group Eugonic
... Dog-bite wound, London, UK Abscess following dog-bite, Montreuil, France Dog-bite wound, Hawaii, USA Dog-bite wound, Paris, France Vagina, Canada ...
... Dog-bite wound, London, UK Abscess following dog-bite, Montreuil, France Dog-bite wound, Hawaii, USA Dog-bite wound, Paris, France Vagina, Canada ...
Role of Hereditary Factors in Weight Loss and Its
... reported more than 600 loci from single-gene mutations in mouse models of obesity, non-syndromic human obesity cases due to single-gene mutations, obesityrelated Mendelian disorders, transgenic and knock-out mice models, QTLs from cross-breeding experiments and genome-wide scans, and genes or marker ...
... reported more than 600 loci from single-gene mutations in mouse models of obesity, non-syndromic human obesity cases due to single-gene mutations, obesityrelated Mendelian disorders, transgenic and knock-out mice models, QTLs from cross-breeding experiments and genome-wide scans, and genes or marker ...
Single-Nucleotide Polymorphism Mapping
... for detecting SNPs by restriction digest, as introduced by Wicks et al. (3), and discuss some alternatives to this approach. When contemplating SNP mapping, three other techniques should be considered. First, mobile DNA elements, or transposons, can be used as mutagens (7). Because insertion of an e ...
... for detecting SNPs by restriction digest, as introduced by Wicks et al. (3), and discuss some alternatives to this approach. When contemplating SNP mapping, three other techniques should be considered. First, mobile DNA elements, or transposons, can be used as mutagens (7). Because insertion of an e ...
Chapter 13 - Microbial Genetics
... postQ: In wild-type E. coli cells in medium with glucose, and no lactose: A. CAP binds to promoter B. Repressor binds to operator C. Both CAP and Repressor bind to promoter and operator, respectively D. Neither bind ...
... postQ: In wild-type E. coli cells in medium with glucose, and no lactose: A. CAP binds to promoter B. Repressor binds to operator C. Both CAP and Repressor bind to promoter and operator, respectively D. Neither bind ...
VCR 221 - Potato - UC Davis Plant Sciences
... Lightbourn GJ, Jelesko JG, Veilleux RE. 2007. Retrotransposon-based markers from potato monoploids used in somatic hybridization. GENOME 50(5): 492-501. link Leonards-Schippers, C., W. Gieffers, R. Schaferpregl and E. Ritter. 1994. Quantitative resistance to Phytophthora infestans in potato - a case ...
... Lightbourn GJ, Jelesko JG, Veilleux RE. 2007. Retrotransposon-based markers from potato monoploids used in somatic hybridization. GENOME 50(5): 492-501. link Leonards-Schippers, C., W. Gieffers, R. Schaferpregl and E. Ritter. 1994. Quantitative resistance to Phytophthora infestans in potato - a case ...
Genetics of host response in leprosy
... Brazil and India, depending on the city, and specifically the area being studied, a variation of 20 –100% exposure to M. leprae is estimated, as evaluated using PGL-I antibody detection (X. Illarramendi, personal communication). Thus, if blood donors are the best choice to obtain healthy controls, i ...
... Brazil and India, depending on the city, and specifically the area being studied, a variation of 20 –100% exposure to M. leprae is estimated, as evaluated using PGL-I antibody detection (X. Illarramendi, personal communication). Thus, if blood donors are the best choice to obtain healthy controls, i ...
Powerpoint template for scientific posters (Swarthmore College)
... Stony Brook University, Department of Biochemistry and Cell Biology and the Center for Developmental Genetics, Stony Brook University, Stony Brook, NY, 11790 ...
... Stony Brook University, Department of Biochemistry and Cell Biology and the Center for Developmental Genetics, Stony Brook University, Stony Brook, NY, 11790 ...
PDF
... cell-cell interaction on embryo development and cell fate determination. The absence of E-cadherin results in disorganized epithelial polarity and an increase in the number of blastomeres expressing CDX2 (De Vries et al., 2004; Stephenson et al., 2010). However, in these studies, E-cadherin mutant e ...
... cell-cell interaction on embryo development and cell fate determination. The absence of E-cadherin results in disorganized epithelial polarity and an increase in the number of blastomeres expressing CDX2 (De Vries et al., 2004; Stephenson et al., 2010). However, in these studies, E-cadherin mutant e ...
Novel p53 mutants selected in BRCA
... 1997). PIG3 is related to a plant gene TED2, implicated in the apoptotic process associated with the formation of meristems, and the mammalian NADPH-quinone oxidoreductase which is a potent inducer of reactive oxygen species (ROS) which are powerful inducers of apoptosis. The importance of transacti ...
... 1997). PIG3 is related to a plant gene TED2, implicated in the apoptotic process associated with the formation of meristems, and the mammalian NADPH-quinone oxidoreductase which is a potent inducer of reactive oxygen species (ROS) which are powerful inducers of apoptosis. The importance of transacti ...
Site-specific recombinase technology

Nearly every human gene has a counterpart in the mouse (regardless of the fact that a minor set of orthologues had to follow species specific selection routes). This made the mouse the major model for elucidating the ways in which our genetic material encodes information. In the late 1980s gene targeting in murine embryonic stem (ES-)cells enabled the transmission of mutations into the mouse germ line and emerged as a novel option to study the genetic basis of regulatory networks as they exist in the genome. Still, classical gene targeting proved to be limited in several ways as gene functions became irreversibly destroyed by the marker gene that had to be introduced for selecting recombinant ES cells. These early steps led to animals in which the mutation was present in all cells of the body from the beginning leading to complex phenotypes and/or early lethality. There was a clear need for methods to restrict these mutations to specific points in development and specific cell types. This dream became reality when groups in the USA were able to introduce bacteriophage and yeast-derived site-specific recombination (SSR-) systems into mammalian cells as well as into the mouse