Identification of eight novel coagulation factor XIII subunit A
... Congenital FXIII deficiency is chiefly caused by mutations in the F13A gene (95% of cases) and, more rarely, by F13B gene defects (5% of cases). The F13A gene, coding for the FXIII A protein subunit, occupies chromosomal position 6p24-25 and comprises 15 exons encoding a 731 amino acid protein [1]. ...
... Congenital FXIII deficiency is chiefly caused by mutations in the F13A gene (95% of cases) and, more rarely, by F13B gene defects (5% of cases). The F13A gene, coding for the FXIII A protein subunit, occupies chromosomal position 6p24-25 and comprises 15 exons encoding a 731 amino acid protein [1]. ...
supporting information
... PLP epitope clusters: We selected the epitope clusters for PLP to reside within amino acids 38-52, 103-150, 177-203, 218-240 and 264-276: The PLP38-52 contains epitopes preferentially recognized by DR2 and D4 MS T-cells [13], one of the H-2d strains, BALB/cPt, is also moderately susceptible to EAE ...
... PLP epitope clusters: We selected the epitope clusters for PLP to reside within amino acids 38-52, 103-150, 177-203, 218-240 and 264-276: The PLP38-52 contains epitopes preferentially recognized by DR2 and D4 MS T-cells [13], one of the H-2d strains, BALB/cPt, is also moderately susceptible to EAE ...
No Slide Title
... depend upon the software being able to find precise information in precise places within a Pathway/Genome DB ...
... depend upon the software being able to find precise information in precise places within a Pathway/Genome DB ...
Identification of a Novel Point Mutation of Mouse Proto
... Accepted for publication August 17, 2004 ABSTRACT Manipulation of the mouse genome has emerged as an important approach for studying gene function and establishing human disease models. In this study, the mouse mutants were generated through N-ethylN-nitrosourea (ENU)-induced mutagenesis in C57BL/6J ...
... Accepted for publication August 17, 2004 ABSTRACT Manipulation of the mouse genome has emerged as an important approach for studying gene function and establishing human disease models. In this study, the mouse mutants were generated through N-ethylN-nitrosourea (ENU)-induced mutagenesis in C57BL/6J ...
Molecular ecology and selection in the drought-
... Moreover, haplotypes with low frequency were more common at Asr2 than at Asr1 (Table 4). A hypothetical haplotype was required to analyze variation in the exon region of Asr1. Furthermore, some patterns suggested by the previous section were revealed by total haplotype frequency for each gene pool d ...
... Moreover, haplotypes with low frequency were more common at Asr2 than at Asr1 (Table 4). A hypothetical haplotype was required to analyze variation in the exon region of Asr1. Furthermore, some patterns suggested by the previous section were revealed by total haplotype frequency for each gene pool d ...
General remarks: A biodesign is a man made, mostly computer
... coming not together by standard methodology or the final two fragments of the assembly process do not go together either by ligation or by recombination. These rules are to be applied provided that the last two fragments of the assembly process are sequence verified and show 100% sequence identity ( ...
... coming not together by standard methodology or the final two fragments of the assembly process do not go together either by ligation or by recombination. These rules are to be applied provided that the last two fragments of the assembly process are sequence verified and show 100% sequence identity ( ...
Mergers and acquisitions: malaria and the great chloroplast heist
... so strange. Molecular phylogenetics had clearly demonstrated that the malaria parasite, along with many other parasites such as Toxoplasma that together make up the phylum Apicomplexa, are the closest relatives of an algal group known as dinoflagellates [4]. And protistologists are becoming accustom ...
... so strange. Molecular phylogenetics had clearly demonstrated that the malaria parasite, along with many other parasites such as Toxoplasma that together make up the phylum Apicomplexa, are the closest relatives of an algal group known as dinoflagellates [4]. And protistologists are becoming accustom ...
Causal Democracy And Causal Contributions In Developmental
... truth or reality, of something essential and deep that stands behind the mere phenotype. That intuition survives one technical correction after another--because it's not about method, but about meaning and being. The homunculoid gene plays mind to environment's matter. It carries a pre-scribed-alrea ...
... truth or reality, of something essential and deep that stands behind the mere phenotype. That intuition survives one technical correction after another--because it's not about method, but about meaning and being. The homunculoid gene plays mind to environment's matter. It carries a pre-scribed-alrea ...
BGS 118, Low number of tillers 1, lnt1
... produce secondary tillers (1). Occasional spike malformations occur in most environments. The spike may have irregular rachis internode lengths and is relatively short. The lower portion of the spike appears more compact than the upper portion (1, 6). Lateral spikelets in two-rowed cultivars are enl ...
... produce secondary tillers (1). Occasional spike malformations occur in most environments. The spike may have irregular rachis internode lengths and is relatively short. The lower portion of the spike appears more compact than the upper portion (1, 6). Lateral spikelets in two-rowed cultivars are enl ...
Supertaster
... understand how these genes work in heredity (passing genes from parent to offspring), see the following Punnett squares that represent various pairings of parents with non-supertaster and supertaster genes: ...
... understand how these genes work in heredity (passing genes from parent to offspring), see the following Punnett squares that represent various pairings of parents with non-supertaster and supertaster genes: ...
Structure and functions of lampbrush chromosomes
... et al., 2009). They can also undergo seasonal changes (Tsvetkov and Parfenov, 1994). This is particularly evident in hibernating amphibians. During the summer, when the animals are the most active, the transcriptional activity of LBCs is the highest, as well. In the autumn, LBCs’ activity abates. Ne ...
... et al., 2009). They can also undergo seasonal changes (Tsvetkov and Parfenov, 1994). This is particularly evident in hibernating amphibians. During the summer, when the animals are the most active, the transcriptional activity of LBCs is the highest, as well. In the autumn, LBCs’ activity abates. Ne ...
Pre-implantation genetic diagnosis
... prevent X-linked disorders have had variable success. The only approach for preconception diagnosis at present, therefore, seems to be genotyping oocytes by biopsing the polar bodies, with subsequent genetic analysis of biopsied material3. The biopsy of the polar body from oocytes provides the possi ...
... prevent X-linked disorders have had variable success. The only approach for preconception diagnosis at present, therefore, seems to be genotyping oocytes by biopsing the polar bodies, with subsequent genetic analysis of biopsied material3. The biopsy of the polar body from oocytes provides the possi ...
v13a1234-lu pgmkr - Molecular Vision
... Abe et al. reported that tyrosinase and TRP1 mRNA could not be detected in established adult human RPE cells in vitro. However, Abe et al. did not study the protein expression of these two enzymes and the expression of TRP2 [18,19]. SmithThomas et al. reported that protein of TRP1 and TRP2 could not ...
... Abe et al. reported that tyrosinase and TRP1 mRNA could not be detected in established adult human RPE cells in vitro. However, Abe et al. did not study the protein expression of these two enzymes and the expression of TRP2 [18,19]. SmithThomas et al. reported that protein of TRP1 and TRP2 could not ...
The hair follicle and its stem cells as drug delivery targets
... therapeutic targets. Hoffman and colleagues have pioneered hair-follicle-specific targeting using liposomes to deliver small and large molecules, including genes. They have also pioneered ex vivo hair-follicle targeting with continued expression of the introduced gene following transplantation. Rece ...
... therapeutic targets. Hoffman and colleagues have pioneered hair-follicle-specific targeting using liposomes to deliver small and large molecules, including genes. They have also pioneered ex vivo hair-follicle targeting with continued expression of the introduced gene following transplantation. Rece ...
Analysis of the first polar body: preconception genetic
... sampling or amniocentesis, respectively, followed by elective termination of affected fetuses. The possibility of diagnosis prior to conception provides an alternative for these high-risk families. In a woman who is a carrier for a single gene mutation such as a-l-AT, the first polar body, in the ab ...
... sampling or amniocentesis, respectively, followed by elective termination of affected fetuses. The possibility of diagnosis prior to conception provides an alternative for these high-risk families. In a woman who is a carrier for a single gene mutation such as a-l-AT, the first polar body, in the ab ...
Prof. Kamakaka`s Lecture 1 Notes (PDF)
... What is the biological significance of the 9:3:3:1 ratio? This ratio is only produced if TWO DIFFERENT GENE PAIRS assort independently of each other during gamete formation. The presence of one gene in a gamete does not influence the probability of another gene being found in that gamete Principle ...
... What is the biological significance of the 9:3:3:1 ratio? This ratio is only produced if TWO DIFFERENT GENE PAIRS assort independently of each other during gamete formation. The presence of one gene in a gamete does not influence the probability of another gene being found in that gamete Principle ...
2.5.6 Genetic Inheritance 2.5.7 Causes of Variation 2.5.8 Evolution
... Q. Human males and females differ in one of their twenty three pairs of chromosomes. What name is given to this pair of chromosomes? Allele only expressed in the homozygous condition ...
... Q. Human males and females differ in one of their twenty three pairs of chromosomes. What name is given to this pair of chromosomes? Allele only expressed in the homozygous condition ...
Mendel`s Experiments
... Mendel thought that there must be something in each plant that controlled its traits. He called these things “factors” but we now call them genes. We also now know that each characteristic (like flower color) is controlled by two genes—one gene is inherited from each parent. The F1 plants have 1 dom ...
... Mendel thought that there must be something in each plant that controlled its traits. He called these things “factors” but we now call them genes. We also now know that each characteristic (like flower color) is controlled by two genes—one gene is inherited from each parent. The F1 plants have 1 dom ...
1 Oviduct-embryo interactions in cattle
... There is clear evidence of a two-way interaction between the uterus and developing conceptus. For example, it has been well demonstrated that circulating progesterone (P4) directly regulates uterine gene expression that, in turn, drives conceptus elongation [2, 3]. Up to the time of maternal recogni ...
... There is clear evidence of a two-way interaction between the uterus and developing conceptus. For example, it has been well demonstrated that circulating progesterone (P4) directly regulates uterine gene expression that, in turn, drives conceptus elongation [2, 3]. Up to the time of maternal recogni ...
BIO301 - National Open University of Nigeria
... set of organisms in which any pair of members can breed together. This implies that all members belong to the same species and live near each other. Population genetics attempts to explain such phenomena as adaptation and speciation leading to evolution of new species.For example, all of the moths ...
... set of organisms in which any pair of members can breed together. This implies that all members belong to the same species and live near each other. Population genetics attempts to explain such phenomena as adaptation and speciation leading to evolution of new species.For example, all of the moths ...
E-Halliburton chapter 9
... A useful understanding of FST is the proportion of the total genetic variance that is due to differences between subpopulations. (The rest of the variance is due to differences between individuals if we consider a simple stucture with only two levels; the total population and the subpopululations). ...
... A useful understanding of FST is the proportion of the total genetic variance that is due to differences between subpopulations. (The rest of the variance is due to differences between individuals if we consider a simple stucture with only two levels; the total population and the subpopululations). ...
Validating Genome-Wide Association Candidates
... Copyright © 2017 American Society of Plant Biologists. All rights reserved. ...
... Copyright © 2017 American Society of Plant Biologists. All rights reserved. ...
Site-specific recombinase technology
Nearly every human gene has a counterpart in the mouse (regardless of the fact that a minor set of orthologues had to follow species specific selection routes). This made the mouse the major model for elucidating the ways in which our genetic material encodes information. In the late 1980s gene targeting in murine embryonic stem (ES-)cells enabled the transmission of mutations into the mouse germ line and emerged as a novel option to study the genetic basis of regulatory networks as they exist in the genome. Still, classical gene targeting proved to be limited in several ways as gene functions became irreversibly destroyed by the marker gene that had to be introduced for selecting recombinant ES cells. These early steps led to animals in which the mutation was present in all cells of the body from the beginning leading to complex phenotypes and/or early lethality. There was a clear need for methods to restrict these mutations to specific points in development and specific cell types. This dream became reality when groups in the USA were able to introduce bacteriophage and yeast-derived site-specific recombination (SSR-) systems into mammalian cells as well as into the mouse